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100g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C4H7N3O. CAS No. 60-27-5. Prepack ID 22377556-100g. Molecular Weight 113.12. See USA prepack pricing.
Creatinine
Creatinine is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body. Synonyms: Creatinine; NSC 13123; NSC-13123; NSC13123. Grades: >98%. CAS No. 60-27-5. Molecular formula: C4H7N3O. Mole weight: 113.12.
Creatinine
Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles. Uses: Scientific research. Group: Natural products. Alternative Names: NSC13123. CAS No. 60-27-5. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-B0504.
Creatinine, 98.5+% USP
Creatinine is the end product of creatine catabolism. Creatinine is a normal constituent of urine. Also found together with creatine in muscle tissues and blood. Creatinine is found in all soils and in grain seeds and other vegetable matter as well as in certain fish and in crab meat extract. Group: Biochemicals. Alternative Names: 2-Amino-1,5-dihydro-1-methyl-4H-imidazol-4-one; 1-Methylglycocyamidine; 1-Methylhydantoin-2-imide; 2-Amino-1-methyl-1,5-dihydroimidazol-4-one; 2-Amino-1-methylimidazolin-4-one; NSC 13123; TEGO Cosmo C 250. Grades: USP. CAS No. 60-27-5. Pack Sizes: 100g, 250g, 1Kg. Molecular Formula: C?H?N?O, Molecular Weight: 113.12. US Biological Life Sciences.
Worldwide
Creatinine-d3
Creatinine-d 3 is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle [1]. Uses: Scientific research. Group: Natural products. Alternative Names: NSC13123-d3. CAS No. 143827-20-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0504S.
The end product of creatine catabolism. Group: Biochemicals. Alternative Names: 2-Amino-1,5-dihydro-1-methyl-d3-4H-imidazol-4-one; 1-Methylhydantoin-d3-2-imide; 4-Amidinosarcosine-d3; Creatinine-methyl-d3. Grades: Highly Purified. CAS No. 143827-20-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
creatinine deaminase
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is creatinine iminohydrolase. Other names in common use include creatinine hydrolase, and creatinine desiminase. This enzyme participates in arginine and proline metabolism. Group: Enzymes. Synonyms: creatinine hydrolase; creatinine desiminase. Enzyme Commission Number: EC 3.5.4.21. CAS No. 37289-15-9. Creatinine Deiminase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4548; creatinine deaminase; EC 3.5.4.21; 37289-15-9; creatinine hydrolase; creatinine desiminase. Cat No: EXWM-4548.
Creatinine hydrochloride
Creatinine hydrochloride. Group: Biochemicals. Alternative Names: 2-Amino-1-methyl-2-imidazolin-4-one hydrochloride. Grades: Highly Purified. CAS No. 19230-81-0. Pack Sizes: 250g. US Biological Life Sciences.
Worldwide
Creatinine hydrochloride 99.5+%
Creatinine hydrochloride 99.5+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 19230-81-0. Pack Sizes: 25g, 100g, 250g, 1Kg, 2.5Kg. US Biological Life Sciences.
Worldwide
Creatinine (Standard)
Creatinine (Standard) is the analytical standard of Creatinine. This product is intended for research and analytical applications. Creatinine (NSC13123) is a breakdown product of creatine phosphate in muscles. Uses: Scientific research. Group: Natural products. CAS No. 60-27-5. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0504R.
Hydrolase for creatinine determination that catalyzes the conversion of creatinine to N-methylhydantoin and ammonia. Rely on the proven diagnostic quality of this product. Applications: Use creatinine deaminase in diagnostic tests for the determination of creatinine in combination with n-carbamoylsarcosine amidase, n-methylhydantoinase (atp-hydrolysing) and sarcosine oxidase. Group: Enzymes. Synonyms: Creatinine hydrolase; creatinine desiminase. Creatinine Deiminase. Activity: 45.0-90.0 U/mg lyophilizate. Stability: At +2 to +8°C within specification range for 12 months. Store dry. Protect from light. Appearance: Beige lyophilizate. Source: Corynebacterium lilium. Creatinine hydrolase; Creatinine deaminase; EC 3.5.4.21; creatinine desiminase. Cat No: DIA-291.
Native Microbial Creatinine Deiminase
In enzymology, a creatinine deaminase (EC 3.5.4.21) is an enzyme that catalyzes the chemical reaction: creatinine + H2O <-> N-methylhydantoin + NH3. Thus, the two substrates of this enzyme are creatinine and H2O, whereas its two products are N-methylhydantoin and NH3. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is creatinine iminohydrolase. Applications: Creatinine deiminase has been used in a study to assess the application of a creatinine-sensitive biosensor for hemodialysis control. creatinine deiminase has also been used in a study to investigate the bioelectronic tongue for the simultaneous determination of urea, creatinine and alkaline ions in clinical samples. Group: Enzymes. Synonyms: EC 3.5.4.21, creatinine hydrolase; creatinine desiminase; creatinine deaminase; 37289-15-9. Enzyme Commission Number: EC 3.5.4.21. CAS No. 37289-15-9. Creatinine Deiminase. Mole weight: mol wt ~260 kDa. Activity: > 25 units/mg protein. Storage: -20°C. Form: Lyophilized powder containing mannitol as stabilizer. Source: Microbial. EC 3.5.4.21, creatinine hydrolase; creatinine desiminase; creatinine deaminase; 37289-15-9. Cat No: NATE-0164.
Native Microorganism Creatinine Deiminase
In enzymology, a creatinine deaminase (EC 3.5.4.21) is an enzyme that catalyzes the chemical reaction: creatinine + H2O <-> N-methylhydantoin + NH3. Thus, the two substrates of this enzyme are creatinine and H2O, whereas its two products are N-methylhydantoin and NH3. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is creatinine iminohydrolase. Applications: This enzyme is useful for enzymatic determination of creatinine when coupled with glutamate dehydrogenase in clinical analysis. Group: Enzymes. Synonyms: Creatinine hydrolase; Creatinine deaminase; EC 3.5.4.21. Enzyme Commission Number: EC 3.5.4.21. CAS No. 37289-15-9. Creatinine Deiminase. Mole weight: approx. 260 kDa. Activity: Grade? 10U/mg-solid or more (containing approx. 30% of stabilizer). Stability: Stable at-20°C for at least one year. Appearance: White amorphous powder, lyophilized. Form: Freeze dried powder. Source: Microorganism. Creatinine hydrolase; Creatinine deaminase; EC 3.5.4.21. Cat No: DIA-186.
Native Pseudomonas sp. Creatinine amidohydrolase
Creatinine Amidohydrolase catalyzes the hydrolytic reaction converting creatinine to creatine. The enzyme is purified from a microorganism. The molecular size of the enzyme is approximately 175,000. The enzyme is useful for the enzy-matic assay of creatinine when coupled with other related enzymes. Creatinine + H2O ? Creatine. Creatininase from pseudomonas sp. is a homohexameric enzyme with a molecular mass of 28.4 kda per subunit. it is a cyclic amidohydrolase catalysing the reversible conversion of creatinine to creatine. each monomer contains a binuclear zinc centre near the c termini of the β-strands and the n termini of the main α-helices. these zinc ions indicate the location of the active site. Applications: This enzyme is useful for enzymatic determination of creatinine when coupled with creatine amidinohydrolase, sarcosine dehydrogenase or sarcosine oxidase and formaldehyde dehydrogenase in clinical analysis. Group: Enzymes. Synonyms: creatininase; creatinine hydrolase; creatinine . Enzyme Commission Number: EC 3.5.2.10. CAS No. 9025-13-2. Creatininase. Mole weight: 175 kDa. Activity: > 250U/mg protein. Storage: 2-8°C. Form: Lyophilized powder containing sucrose and BSA as stabilizers. Source: Pseudomonas sp. creatininase; creatinine hydrolase; creatinine amidohydrolase; EC 3.5.2.10; 9025-13-2. Cat No: DIA-130.
Serotonin creatinine sulfate monohydrate
Serotonin creatinine sulfate monohydrate. Group: Biochemicals. Grades: Reagent Grade. CAS No. 61-47-2. Pack Sizes: 1g, 5g. US Biological Life Sciences.
Worldwide
2-(4-Benzyloxy-indol-3-yl)ethanamine Hemisulfate Salt
A tryptamine derivative, also an intermediate in the synthesis of the neurotransmitter agonist 4-Hydroxytryptamine Creatinine. Group: Biochemicals. Alternative Names: 2-(4-Benzyloxy-1H-indol-3-yl)ethylamine; 4-(Phenylmethoxy)-1H-indole-3-ethanamine Hemisulfate Salt. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
A tryptamine derivative, also an intermediate in the synthesis of the neurotransmitter agonist 4-Hydroxytryptamine Creatinine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
4-Benzyloxygramine
A A benzyloxyindole derivative, also an intermediate in the synthesis of the neurotransmitter agonist 4-Hydroxytryptamine Creatinine. Group: Biochemicals. Alternative Names: N,N-Dimethyl-4-(phenylmethoxy)-1H-indole-3-methanamine. Grades: Highly Purified. CAS No. 13523-95-0. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
4-Benzyloxyindole-3-acetonitrile
A tryptamine derivative, also an intermediate in the synthesis of the neurotransmitter agonist 4-Hydroxytryptamine Creatinine. Group: Biochemicals. Alternative Names: 4-Benzyloxy-3-indoleacetonitrile; 4-(Phenylmethoxy)-1H-indole-3-acetonitrile. Grades: Highly Purified. CAS No. 1464-11-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
5-Hydroxytryptamine creatine sulfate monohydrate
5-Hydroxytryptamine creatine sulfate monohydrate. Group: Biochemicals. Alternative Names: Serotonin creatinine sulfate. Grades: Highly Purified. CAS No. 61-47-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C14H19N5O2·H2SO4·H2O. US Biological Life Sciences.
Worldwide
α-Lipoic Acid
α-Lipoic Acid is a metabolic antioxidant that regulates NFκB signal transduction and can protect against oxidative injury. The exogenous compound is reduced intracellularly by enzymes. Its reduced form is involved in radical scavenging, recycling of other antioxidants, accelerating GSH synthesis, and regulating transcription factor activity, specifically NFkappaB. It also acts as a conenzyme that is required for the activity of pyruvate dehydrogenase and glycine decarboxylase, among other enzyme complexes. Studies show that it can prevent a decrease in the renal antioxidant defense system and prevent the increase of lipid peroxidation, platinum content and plasma creatinine concentrations. In other studies, lipoic acid decreased the phagocytosis of myelin by macrophages, acting as a non-specific scavenger of reactive oxygen species (ROS). Applications: A metabolic antioxidant that regulates nf-κb signal transduction. Group: Coenzymes. Synonyms: DL-Thioctic Acid; DL-6,8-Dithiooctanoic acid; 1,2-Dithiolane-3-valeric acid. CAS No. 1077-28-7. Purity: ≥95%. Mole weight: 206.32. Form: Solid. DL-Thioctic Acid; DL-6,8-Dithiooctanoic acid; 1,2-Dithiolane-3-valeric acid; α-Lipoic Acid; 1077-28-7. Cat No: COEC-041.
Ankaflavin
A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: 2H-Furo[3,?2-g]?[2]?benzopyran-2,?9(3H)?-dione, 3a,?4,?8,?9a-tetrahydro-9a-methyl-3-(1-oxooctyl)?-6-(1E)?-1-propen-1-yl-, (3S,?3aR,?9aR)?-. Grades: > 95%. CAS No. 50980-32-0. Molecular formula: C23H30O5. Mole weight: 386.49.
Bromocresol green
Bromocresol green is a pH-sensitive triphenylmethane dye commonly used for the determination of protein and albumin in serum. Bromocresol green is a bio-based dye with a yellow-green to blue-green color. Bromocresol green turns yellow (λmax=435 nm, protonated form) when placed in acidic solution (e.g. pH=4.15), and turns blue in basic solution (λmax=615 nm, deprotonated form). Bromocresol green is widely used as a pH indicator in the field of biochemical analysis. In addition, Bromocresol green is also used to detect the concentration of molecules such as creatinine, and to judge the viability of cells [1] [2] [3] [4]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 76-60-8. Pack Sizes: 10 mM * 1 mL; 25 g; 50 g; 100 g. Product ID: HY-W040144.
Chemically modified Cucurbita species Ascorbate Oxidase
Oxidoreductase that oxidizes ascorbic acid to dehydroascorbate. Take advantage of the improved stability in liquid reagents. Rely on the proven diagnostic quality of this product. Applications: Use ascorbate oxidase, chemically modified, in a variety of diagnostic tests to eliminate the interference of ascorbic acid, since ascorbic acid interferes with the trinder reaction that is widely used for the colorimetric determination of analytes. it is useful in liquid as well as dry chemistry test, e.g., for the determination of uric acid, lactate or creatinine. Group: Enzymes. Synonyms: ascorbase; ascorbic acid oxidase; ascorbate oxidase; ascorbic oxidase; ascorbate dehydrogenase; L-ascorbic acid oxidase; AAO; L-ascorbate: O2 oxidoreductase; AA oxidase; L-ascorbate oxidase. AAO. Mole weight: Approximately 140 kD. Activity: >180 U/mg lyophilizate (+37°C, L-ascorbate); Specific activity (+37°C): >1,800 U/mg protein. Stability: At -15 to -25°C within specification range for 12 months. Store dry. Keep tightly sealed. Appearance: Turquoise lyophilizate. Source: Cucurbita species. ascorbase; ascorbic acid oxidase; ascorbate oxidase; ascorbic oxidase; ascorbate dehydrogenase; L-ascorbic acid oxidase; AAO; L-ascorbate: O2 oxidoreductase; AA oxidase; EC 1.10.3.3; 9029-44-1; L-ascorbate oxidase. Cat No: DIA-283.
Creatinase from Pseudomonas sp., Recombinant
In enzymology, a creatinase (EC 3.5.3.3) is an enzyme that catalyzes the chemical reaction:creatine + H2O<-> sarcosine + urea. Thus, the two substrates of this enzyme are creatine and H2O, whereas its two products are sarcosine and urea. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. Creatinase accelerates the conversion reaction of creatine and water molecule to sarcosine and urea. It always acts in homodimer state and is induced by choline chloride. Recombinant, expressed in e. coli, lyophilized powder, 10-15 units/mg protein. Applications: Creatine amidinohydrolase is a clinically important enzyme used in the determination of creatinine in blood and urine. Group: Enzymes. Synonyms: Creatine amidinohydrolase; creatinase; 37340-58-2; EC 3.5.3.3. Enzyme Commission Number: EC 3.5.3.3. CAS No. 37340-58-2. Creatinase. Activity: 10-20 units/mg protein. Stability: 2-8°C. Form: lyophilized powder. Source: E. coli. Species: Pseudomonas sp. Creatine amidinohydrolase; creatinase; 37340-58-2; EC 3.5.3.3. Cat No: NATE-0162.
Creatinase, microorganism
Creatine amidinohydrolase, microorganism is a hydrolytic enzyme that catalyzes the hydrolysis of creatine into creatinine and urea, playing a crucial role in the measurement of creatinine concentration. Creatine amidinohydrolase, microorganism can be used in the development of biosensors for measuring serum creatinine levels [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Creatine amidinohydrolase, microorganism. CAS No. 37340-58-2. Pack Sizes: 1 KU; 5 KU. Product ID: HY-P2893B.
Creatine-[guanidino-13C] monohydrate
Creatine-[guanidino-13C] monohydrate, is the labelled analogue of Creatinine. Creatine is found in vertebrates where it facilitates recycling of adenosine triphosphate (ATP). Creatine can be used as a buffer. Synonyms: 4-Amidinosarcosine-(guanidino-13C) monohydrate; Creatine monohydrate-(guanidino-13C). Grades: 99% atom 13C. CAS No. 335081-01-1. Molecular formula: C3[13C]H11N3O3. Mole weight: 150.14.
Creatine-[methyl-13C] monohydrate
Creatine-[methyl-13C] monohydrate, is the labelled analogue of Creatinine. Creatine is found in vertebrates where it facilitates recycling of adenosine triphosphate (ATP). Creatine can be used as a buffer. Synonyms: 4-Amidinosarcosine-methyl-13C monohydrate; Creatine-(methyl-13C) monohydrate; Creatine monohydrate-(methyl-13C). Grades: 99% atom 13C. Molecular formula: C3[13C]H11N3O3. Mole weight: 150.14.
Creatine-[methyl-d3] monohydrate
Creatine-[methyl-d3] monohydrate, is the labelled analogue of Creatinine. Creatine is found in vertebrates where it facilitates recycling of adenosine triphosphate (ATP). Creatine can be used as a buffer. Synonyms: 4-Amidinosarcosine-methyl-d3 monohydrate; Creatine-(methyl-d3) monohydrate. Grades: 99% by CP; 98% atom D. CAS No. 284664-86-4. Molecular formula: C4H8D3N3O3. Mole weight: 152.17.
creatininase
Creatininase is a member of the urease-related amidohydrolases, the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. The systematic name of this enzyme class is creatinine amidohydrolase. This enzyme is also called creatinine hydrolase. This enzyme participates in arginine and proline metabolism. Group: Enzymes. Synonyms: creatinine hydrolase. Enzyme Commission Number: EC 3.5.2.10. CAS No. 9025-13-2. Creatininase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4493; creatininase; EC 3.5.2.10; 9025-13-2; creatinine hydrolase. Cat No: EXWM-4493.
Creatininase from E. coli, Recombinant
Creatininase from Pseudomonas sp. is a homohexameric enzyme with a molecular mass of 28.4 kDa per subunit. It is a cyclic amidohydrolase catalysing the reversible conversion of creatinine to creatine. Each monomer contains a binuclear zinc centre near the C termini of the β-strands and the N termini of the main α-helices. These zinc ions indicate the location of the active site. Group: Enzymes. Synonyms: EC 3.5.2.10, creatinine hydrolase; Creatininase; 9025-13-2. Enzyme Commission Number: EC 3.5.2.10. Mole weight: ca. 170 kDa. Activity: > 100 U/mg. Appearance: White lyophilizate. Storage: at -20°C. Source: E. coli. Species: E. coli. EC 3.5.2.10, creatinine hydrolase; Creatininase; 9025-13-2. Cat No: NATE-1242.
Creatininase, Microorganism
Creatininase, Microorganism (Creatinine amidohydrolase; CAH), namely creatinine amidohydrolase, from Pseudomonas putida , is a homohexameric enzyme commonly used in biochemical research. Creatininase acts on carbon-nitrogen bonds other than peptide bonds, and can catalyze the hydrolysis of creatinine to creatine, which can then be metabolized by creatinase to urea and sarcosine [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Creatinine amidohydrolase; CAH. CAS No. 9025-13-2. Pack Sizes: 1 KU. Product ID: HY-P2838.
Ketone monoester
Ketone monoester is an orally available ketone monoester that serves as a source of nutritional ketones. Ketone monoester increases plasma beta-hydroxybutyrate, acetoacetate, blood glucose, blood sodium, and blood creatinine levels in mouse models. Ketone monoester has the potential to improve athletic performance and endurance in animals. Ketone monoester partially prevents myasthenia in septic mice. Ketone monoester may also be used to study Parkinson's disease or diabetes [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1208313-97-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-15344.
lysine carboxypeptidase
A zinc enzyme found in plasma. Inactivates bradykinin and anaphylatoxins in blood plasma. In peptidase family M14 (carboxypeptidase A family). Group: Enzymes. Synonyms: carboxypeptidase N; arginine carboxypeptidase; kininase I; anaphylatoxin inactivator; plasma carboxypeptidase B; creatine kinase conversion factor; bradykinase; kininase Ia; hippuryllysine hydrolase; bradykinin-decomposing enzyme; protaminase; CPase N; creatinine kinase convertase; peptidyl-L-lysine(-L-arginine) hydrolase; CPN. Enzyme Commission Number: EC 3.4.17.3. CAS No. 9013-89-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4077; lysine carboxypeptidase; EC 3.4.17.3; 9013-89-2; carboxypeptidase N; arginine carboxypeptidase; kininase I; anaphylatoxin inactivator; plasma carboxypeptidase B; creatine kinase conversion factor; bradykinase; kininase Ia; hippuryllysine hydrolase; bradykinin-decomposing enzyme; protaminase; CPase N; creatinine kinase convertase; peptidyl-L-lysine(-L-arginine) hydrolase; CPN. Cat No: EXWM-4077.
Monascin
Monascin is a pigment that displays more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: Monascoflavin; 2H-Furo[3,?2-g]?[2]?benzopyran-2,?9(3H)?-dione, 3a,?4,?8,?9a-tetrahydro-9a-methyl-3-(1-oxohexyl)?-6-(1E)?-1-propen-1-yl-, (3S,?3aR,?9aR)?-. Grades: >95%. CAS No. 21516-68-7. Molecular formula: C21H26O5. Mole weight: 358.44.
Monascorubramin
A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxooctyl)-6-(1E)-1-propen-1-yl-, (9aR)-; (9aR)-9a-Methyl-3-(1-oxooctyl)-6-(1E)-1-propen-1-ylfuro[3,2-g]isoquinoline-2,9(7H,9aH)-dione; Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxooctyl)-6-(1-propenyl)-, [R-(E)]-; Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxooctyl)-6-(1E)-1-propenyl-, (9aR)-; Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-octanoyl-6-propenyl-; Monascamine; Δ6(2H),α-Isoquinolineacetic acid, 7,8-dihydro-7-hydroxy-7-methyl-α-octanoyl-8-oxo-3-propenyl-, γ-lactone; Monascamin; Monascorubramine. Grades: ≥95%. CAS No. 3627-51-8. Molecular formula: C23H27NO4. Mole weight: 381.48.
Monascorubrin
A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: 2H-Furo[3,?2-g]?[2]?benzopyran-2,?9(9aH)?-dione, 9a-methyl-3-(1-oxooctyl)?-6-(1E)?-1-propen-1-yl-, (9aR)?-. Grades: > 95%. CAS No. 13283-90-4. Molecular formula: C21H26O5. Mole weight: 382.46.
N6-Benzyladenine Hydrochloride (BA)
N-Benzyl-9H-purin-6-amine Hydrochloride can be used as reagent/reactant of N6-substituted adenines and as protonated benzylaminopurine and creatinine salts for synthetic preparation of ruthenium DMSO chloro zwitterionic inner-sphere complexes. BA is a cytokinin which stimulates plant growth and development. Across kingdoms, cytokinins were studied on isolated rat atria, and benzylaminopurine was the most potent at eliciting a positive inotropic effect. Group: Biochemicals. Alternative Names: N-6-Benzyladenine Hydrochloride; 6-Benzylaminopurine Hydrochloride; N-(Phenylmethyl)-1H-purin-6-amine Monohydrochloride; N-(Phenylmethyl)-9H-purin-6-amine Hydrochloride. Grades: Highly Purified. CAS No. 162714-86-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C12H11N5·HCl, Molecular Weight: 261.71. US Biological Life Sciences.
Worldwide
Native Acremonium sp. Ascorbate Oxidase
In enzymology, a L-ascorbate oxidase (EC 1.10.3.3) is an enzyme that catalyzes the chemical reaction:2 L-ascorbate + O2<-> 2 dehydroascorbate + 2 H2O. Thus, the two substRates of this enzyme are L-ascorbate and O2, whereas its two products are dehydroascorbate and H2O. This enzyme belongs to the family of oxidoreductases, specifically those acting on diphenols and related substances as donor with oxygen as acceptor. This enzyme participates in ascorbate metabolism. It employs one cofactor, copper. Applications: This enzyme is useful for avoidance from interference of ascorbic acid on diagnostic assay such as blood, uric acid, tg, tc and creatinine. Group: Enzymes. Synonyms: ascorbase; ascorbic acid oxidase; ascorbate oxidase; ascorbic oxidase; ascorbate dehydrogenase; L-ascorbic acid oxidase; AAO; L-ascorbate:O2 oxidoreductase;. Enzyme Commission Number: EC 1.10.3.3. CAS No. 9029-44-1. AAO. Mole weight: 80 kDa?gel filtration?. Activity: > 200 U/mg. Appearance: Light blue amorphous powder, lyophilized. Storage: Storage at ?20°C in the presence of a desiccant is recommended. Form: Freeze dried powder. Source: Acremonium sp. ascorbase; ascorbic acid oxidase; ascorbate oxidase; ascorbic oxidase; ascorbate dehydrogenase; L-ascorbic acid oxidase; AAO; L-ascorbate:O2 oxidoreductase; AA oxidase; EC 1.10.3.3; L-ascorbate oxidase. Cat No: NATE-0864.
Native Actinobacillus sp. Creatinase
In enzymology, a creatinase (EC 3.5.3.3) is an enzyme that catalyzes the chemical reaction:creatine + H2O? sarcosine + urea. Thus, the two substrates of this enzyme are creatine and H2O, whereas its two products are sarcosine and urea. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. Creatinase accelerates the conversion reaction of creatine and water molecule to sarcosine and urea. It always acts in homodimer state and is induced by choline chloride. Applications: Creatinase mixed with sarcosine oxidase may be used to determine the level of creatine in different ph, temperature, enzyme ratio, and buffer concentration. it may also be used to determine the plasma creatinine level by using a centrifugal analyser. Group: Enzymes. Synonyms: Creatine amidinohydrolase; creatinase; 37340-58-2; EC 3.5.3.3. Enzyme Commission Number: EC 3.5.3.3. CAS No. 37340-58-2. Mole weight: mol wt ~100 kDa. Activity: 6.0 U/mg-solid or more. Storage: -20°C. Form: Lyophilized powder containing sugars and EDTA as stabilizers. Source: Actinobacillus sp. Creatine amidinohydrolase; creatinase; 37340-58-2; EC 3.5.3.3. Cat No: NATE-0160.
Native Bacillus sp. Hexokinase
A hexokinase is an enzyme that phosphorylates hexoses (six-carbon sugars), forming hexose phosphate. In most organisms, glucose is the most important substrate of hexokinases, and glucose-6-phosphate the most important product. Hexokinase can transfer an inorganic phosphate group from ATP to a substrate. Hexokinases should not be confused with glucokinase, which is a specific isoform of hexokinase. While other hexokinases are capable of phosphorylating several hexoses, glucokinase acts with a 50-fold lower substrate affinity and its only hexose substrate is glucose. Applications: This enzyme is useful for enzymatic determination of glucose or creatinine kinase activity when coupled with glucose-6-phosphate dehydrogenase. Group: Enzymes. Synonyms: hexokinase (phosphorylating); ATP-dependent hexokinase; glucose ATP phosphotransferase; hexokinase; ATP:D-hexose 6-phosphotransferase. Enzyme Commission Number: EC 2.7.1.1. CAS No. 9001-51-8. Hexokinase. Mole weight: 68 kDa (gel filtration). Activity: More than 250 U/mg solid. Appearance: White amorphous powder, lyophilized. Storage: Storage at -20°C in the presence of a desiccant is recommended. Form: Freeze dried powder. Source: Bacillus sp. hexokinase (phosphorylating); ATP-dependent hexokinase; glucose ATP phosphotransferase; hexokinase; ATP:D-hexose 6-phosphotransferase; EC 2.7.1.1. Cat No: NATE-1157.
Native Bacillus stearothermophilius NAD Synthetase
In enzymology, a NAD+ synthase (EC 6.3.1.5) is an enzyme that catalyzes the chemical reaction:ATP + deamido-NAD+ + NH3<-> AMP + diphosphate + NAD+. The 3 substrates of this enzyme are ATP, deamido-NAD+, and NH3, whereas its 3 products are AMP, diphosphate, and NAD+. This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds as acid-D-ammonia (or amine) ligases (amide synthases). This enzyme participates in nicotinate and nicotinamide metabolism and nitrogen metabolism. Is an enzyme produced by microorganisms. this product shall be used for a diagnostics reagent. Applications: Useful for enzymatic determination of atp, ammonia, urea or creatinine. it is also suitable for enzymatic cycling method. Group: Enzymes. Synonyms: EC 6.3.1.5; 9032-69-3; NAD+ synthetase; NAD+ synthase; nicotinamide adenine dinucleotide synthetase; diphosp. Enzyme Commission Number: EC 6.3.1.5. CAS No. 9032-69-3. NAD Synthetase. Mole weight: 50 kDa (gel filtration); 25 kDa (SDS-PAGE). Activity: > 1 U/mg. Appearance: White powder. Storage: Storage at-20°C in the presence of a desiccant is recommended. Form: Freeze dried powder. Source: Bacillus stearothermophilius. EC 6.3.1.5; 9032-69-3; NAD+ synthetase; NAD+ synthase; nicotinamide adenine dinucleotide synthetase; diphosphopyridine nucleotide synthetase. Cat No: NATE-0471.
Native E. coli N-Carbamoylsarcosine Amidase
In enzymology, a N-carbamoylsarcosine amidase is an enzyme that catalyzes the chemical reaction: N-carbamoylsarcosine + H2O rightleftharpoons sarcosine + CO2 + NH3. Thus, the two substrates of this enzyme are N-carbamoylsarcosine and H2O, whereas its 3 products are sarcosine, CO2, and NH3. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. This enzyme participates in arginine and proline metabolism. Hydrolase that catalyzes the interconversion of n-carbamoylsarcosine to sarcosine. Applications: Use n-carbamoylsarcosine amidase in diagnostic tests for the determination of creatinine in combination with creatinine deaminase, n-methylhydantoinase (atp-hydrolysing) and sarcosine oxidase. Group: Enzymes. Synonyms: N-carbamoylsarcosine amidase; N-carbamoylsarcosine amidohydrolase; carbamoylsarcosine amidase. CAS No. 92767-52-7. N-Carbamoylsarcosine Amidase. Activity: 0.80-1.30 U/mg. Stability: At -15 to -25°C within specification range for 12 months. Store dry. Protect from light. Appearance: White lyophilizate. Source: E. coli. Species: E. coli. N-carbamoylsarcosine amidase; N-carbamoylsarcosine amidohydrolase; carbamoylsarcosine amidase. Cat No: NATE-0876.
Native E.coli Sarcosine Oxidase
Oxidoreductase that catalyzes the demethylation of sarcosine to glycine. Use Sarcosine Oxidase in your preferred creatinine reagent mix and rely on the proven diagnostic quality of this product. Applications: Use sarcosine oxidase in diagnostic tests for the determination of creatinine. this can be done using one of two methods: (1) in combination with creatinase and creatininase. (2) in combination with creatinine deaminase, n-carbamoylsarcosine amidase and n-methylhydantoinase (atp-hydrolyzing). Group: Enzymes. Synonyms: Sarcosine Oxidase; SAO. CAS No. 9029-22-5. SAO. Mole weight: 40 kD. Activity: 22-40 U/mg lyophilizate; >45 U/mg protein. Stability: At -15 to -25°C within specification range for 12 months. Store dry. Protect from light. Appearance: Yellow lyophilizate. Source: E. coli. Sarcosine Oxidase; EC 1.5.3.1; SAO. Cat No: DIA-290.
Native Microorganism Creatine Amidinohydrolase
Creatine Amidinohydrolase catalyzes the hydrolytic reaction converting creatine to sarcosine and urea. The enzyme is purified from a microorganism. The molecular weight of the enzyme is approximately 67,000. The enzyme is useful for the enzymatic assay of creatine and creatinine when coupled with other related enzymes. creatine + H2O ? sarcosine + urea. Applications: This enzyme is useful for enzymatic determination of creatinine when coupled with creatinine amidohydrolase, sarcosine dehydrogenase or sarcosine oxidase and formaldehyde dehydrogenase in clinical analysis. Group: Enzymes. Synonyms: Creatine Amidinohydrolase; Creatinase; EC 3.5.3.3. Enzyme Commission Number: EC 3.5.3.3. CAS No. 37340-58-2. Creatinase. Mole weight: approx. 67 kDa (by gel filtration). Activity: Grade? 4.0 U/mg-solid or more. Stability: Stable at -20°C for at least one year. Appearance: White amorphous powder, lyophilized. Form: Freeze dried powder. Source: Microorganism. Creatine amidohydrolase; Creatinase; EC 3.5.3.3. Cat No: DIA-185.
Native Microorganism Creatine Amidohydrolase
In enzymology, a creatinase (EC 3.5.3.3) is an enzyme that catalyzes the chemical reaction: creatine + H2O ?sarcosine + urea. Thus, the two substrates of this enzyme are creatine and H2O, whereas its two products are sarcosine and urea. The native enzyme was shown to be made up of two subunit monomers via SDS-polyacrylamide gel electrophoresis. Creatinase has been found to be most active at pH 8 and is most stable between ph 6-8 for 24 hrs. at 37 degrees. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. This enzyme participates in arginine and proline metabolism. Applications: This enzyme is useful for enzymatic determination of creatinine when coupled with creatine amidinohydrolase, sarcosine dehydrogenase or sarcosine oxidase and formaldehyde dehydrogenase in clinical analysis. Group: Enzymes. Synonyms: Creatine amidohydrolase; Creatinase; EC 3.5.3.3. Enzyme Commission Number: EC 3.5.3.3. CAS No. 37340-58-2. Mole weight: approx. 67 kDa (by gel filtration). Activity: 4.0 U/mg-solid or more. Appearance: White amorphous powder, lyophilized. Form: Freeze dried powder. Source: Microorganism. Creatine amidohydrolase; Creatinase; EC 3.5.3.3. Cat No: DIA-185.
Native Microorganism D-lactate dehydrogenase
A lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells (animals, plants, and prokaryotes). LDH catalyzes the conversion of pyruvate to lactate and back, as it converts NADH to NAD+ and back. A dehydrogenase is an enzyme that transfers a hydride from one molecule to another. Applications: This enzyme is useful for enzymatic determination of numerous metabolites, e.g.atp, adp, glucose, creatinine, pyruvate, lactate and glycerol, and of enzyme activities, e.g.gpt, pk and cpk when coupled with the related enzymes. Group: Enzymes. Synonyms: Lactate dehydrogenase; EC 1.1.1.27; LDH; LD. Enzyme Commission Number: EC 1.1.1.27. CAS No. 9001-60-9. Activity: 400U/mg-solid or more. Appearance: White amorphous powder, lyophilized. Storage: Store at -20°C. Form: Freeze dried powder. Source: Microorganism. Lactate dehydrogenase; EC 1.1.1.27; LDH; LD. Cat No: DIA-207.
Native Microorganism Sarcosine Oxidase
Sarcosine oxidase (SAO) is an enzyme that catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, 5, 10-CH2-tetrahydrofolate in a reaction requiring H4-tetrahydrofolate and oxygen. sarcosine + H2O + O2 = glycine + formaldehyde + H2O2. Applications: This enzyme is useful for enzymatic determination of creatinine, creatine, and sarcosine when coupling with creatinine amidohydrolase and creatine amidinohydrolase.-341 is newer type of sarosine oxidase, with improved stability in antimicrobial reagent. Group: Enzymes. Synonyms: Sarcosine Oxidase; EC 1.5.3.1; SAO. Enzyme Commission Number: EC 1.5.3.1. CAS No. 9029-22-5. SAO. Mole weight: approx. 65 kDa (by gel filtration). Activity: Grade? 8.0U/mg-solid or more. Stability: Stable at-20°C for at least one year. Appearance: Yellowish amorphous powder, lyophilized. Form: Freeze dried powder. Source: Microorganism. Sarcosine Oxidase; EC 1.5.3.1; SAO. Cat No: DIA-171.
Native microorganisms Creatininase
Creatininase from Pseudomonas sp. is a homohexameric enzyme with a molecular mass of 28.4 kDa per subunit. It is a cyclic amidohydrolase catalysing the reversible conversion of creatinine to creatine. Each monomer contains a binuclear zinc centre near the C termini of the β-strands and the N termini of the main α-helices. These zinc ions indicate the location of the active site. Protein determined by biuret. Applications: This enzyme is useful for enzymatic determination of creatinine when coupled with creatine amidinohydrolase, sarcosine dehydrogenase or sarcosine oxidase and formaldehyde dehydrogenase in clinical analysis. Group: Enzymes. Synonyms: EC 3.5.2.10, creatinine hydrolase; Creatininase; 9025-13-2. Enzyme Commission Number: EC 3.5.2.10. CAS No. 9025-13-2. Creatininase. Mole weight: mol wt ~175 kDa. Activity: 100-300 units/mg protein. Storage: 2-8°C. Form: Lyophilized powder containing sucrose and BSA as stabilizers. Source: microorganisms. EC 3.5.2.10, creatinine hydrolase; Creatininase; 9025-13-2. Cat No: NATE-0163.
Native Porcine heart Lactate dehydrogenase
A lactate dehydrogenase (LDH or LD) is an enzyme found in nearly all living cells (animals, plants, and prokaryotes). LDH catalyzes the conversion of pyruvate to lactate and back, as it converts NADH to NAD+ and back. A dehydrogenase is an enzyme that transfers a hydride from one molecule to another. Applications: This enzyme is useful for enzymatic determination of numerous metabolites, e.g.atp, adp, glucose, creatinine, pyruvate, lactate and glycerol, and of enzyme activities, e.g.gpt, pk and cpk when coupled with the related enzymes. Group: Enzymes. Synonyms: Lactate dehydrogenase; EC 1.1.1.27; LDH; LD. Enzyme Commission Number: EC 1.1.1.27. CAS No. 9001-60-9. LDH. Mole weight: 115 kDa±6,500. Activity: Grade? 2,000U/ml or more. Stability: Stable at 5°C for at least one year. Appearance: Crystalline suspension in 1.6M ammonium sulfate solution. Source: Porcine heart. Species: Porcine. Lactate dehydrogenase; EC 1.1.1.27; LDH; LD. Cat No: DIA-206.
Native Rhodothermus obamensis Hexokinase
A hexokinase is an enzyme that phosphorylates hexoses (six-carbon sugars), forming hexose phosphate. In most organisms, glucose is the most important substrate of hexokinases, and glucose-6-phosphate the most important product. Hexokinase can transfer an inorganic phosphate group from ATP to a substrate. Hexokinases should not be confused with glucokinase, which is a specific isoform of hexokinase. While other hexokinases are capable of phosphorylating several hexoses, glucokinase acts with a 50-fold lower substrate affinity and its only hexose substrate is glucose. Applications: This enzyme is useful for enzymatic determination of glucose or creatinine kinase activity when coupled with glucose-6-phosphate dehydrogenase. Group: Enzymes. Synonyms: hexokinase (phosphorylating); ATP-dependent hexokinase; glucose ATP phosphotransferase; hexokinase; ATP:D-hexose 6-. Enzyme Commission Number: EC 2.7.1.1. CAS No. 9001-51-8. Hexokinase. Mole weight: 140 kDa (gel filtration). Activity: 100 - 400 U/mg. Appearance: White to light grayish lyophilized powder. Storage: Storage at -20°C in the presence of a desiccant is recommended. Form: Freeze dried powder. Source: Rhodothermus obamensis. hexokinase (phosphorylating); ATP-dependent hexokinase; glucose ATP phosphotransferase; hexokinase; ATP:D-hexose 6-phosphotransferase; EC 2.7.1.1. Cat No: NATE-1156.
N-Methylhydantoin
N-Methylhydantoin is a product of degradation of creatinine by bacteria. Uses: Scientific research. Group: Natural products. Alternative Names: 1-Methylhydantoin. CAS No. 616-04-6. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-113382.
N-methylhydantoinase (ATP-hydrolysing)
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. This enzyme participates in arginine, creatinine, and proline metabolism. Group: Enzymes. Synonyms: N-methylhydantoin amidohydrolase; methylhydantoin amidase; N-methylhydantoin hydrolase; N-methylhydantoinase; N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing). Enzyme Commission Number: EC 3.5.2.14. CAS No. 100785-00-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4497; N-methylhydantoinase (ATP-hydrolysing); EC 3.5.2.14; 100785-00-0; N-methylhydantoin amidohydrolase; methylhydantoin amidase; N-methylhydantoin hydrolase; N-methylhydantoinase; N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing). Cat No: EXWM-4497.
N-Methylhydantoinase (ATP-hydrolyzing) from Arthrobacter sp., Recombinant
In enzymology, a N-methylhydantoinase (ATP-hydrolysing) is an enzyme that catalyzes the chemical reaction: ATP + N-methylimidazolidine-2,4-dione + 2 H2O rightleftharpoons ADP + phosphate + N-carbamoylsarcosine. The 3 substrates of this enzyme are ATP, N-methylimidazolidine-2,4-dione, and H2O, whereas its 3 products are ADP, phosphate, and N-carbamoylsarcosine. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amides. This enzyme participates in arginine, creatinine, and proline metabolism. Hydrolase for creatinine determination that uses atp to catalyze the conversion of...amoylsarcosine amidase and sarcosine oxidase. Group: Enzymes. Synonyms: N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing); N-methylhydantoin amidohydrolase; methylhydantoin amidase; N-methylhydantoin hydrolase; N-methylhydantoinase. N-Methylhydantoinase. Activity: 0.6-1.0 U/ mg. Stability: At -15 to -25°C within specification range for 12 months. Store dry. Protect from light. Appearance: White lyophilizate. Source: E. coli. Species: Arthrobacter sp. N-methylimidazolidine-2,4-dione amidohydrolase (ATP-hydrolysing); N-methylhydantoin amidohydrolase; methylhydantoin amidase; N-methylhydantoin hydrolase; N-methylhydantoinase. Cat No: NATE-0904.
PG490-88
PG490-88 is a semisynthetic derivative of the novel compound PG490 (triptolide) purified from a Chinese herb. It has been shown to prolong acute allograft survival in multiple experimental organ transplant models. However, the effect of PG490-88 on prevention of acute and chronic renal allograft rejection has not been determined. Kidneys of ACI or F344 rats were transplanted into bilaterally nephrectomized LEW recipients as the acute or chronic allograft rejection models, respectively. Treatment of LEW recipients with PG490-88 significantly prolonged ACI kidney graft survival in a dose-dependent manner when compared with the untreated allograft controls. LEW recipients of F344 kidney grafts who received PG490-88 for 90 days with a brief course of low-dose FK506 showed normal serum creatinine levels and markedly reduced histological changes of chronic rejection at day 90 after transplantation. These results suggest that PG490-88 significantly prolongs kidney allograft survival in an acute rejection model and prevents chronic allograft rejection in rats. Synonyms: Omtriptolide; PG490 88; YM 262; YM-262; YM262; 4-{[(3bS, 4aS, 5aR, 6R, 6aS, 7aS, 7bS, 8aS, 8bS)-6a-Isopropyl-8b-methyl-1-oxo-1, 3, 3b, 4, 4a, 6, 6a, 7a, 7b, 8b, 9, 10-dodecahydrotrisoxireno[6, 7:8a, 9:4b, 5]phenanthro[1, 2-c]furan-6-yl]oxy}-4-oxobutanoic acid. Grades: ≥98%. CAS No. 195883-06-8. Molecular formula: C24H28O9. Mole weight: 460.47.
Rubropunctamine
A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxohexyl)-6-(1-propenyl)-, [R-(E)]-; Furo[3,2-g]isoquinoline-2,9(7H,9aH)-dione, 9a-methyl-3-(1-oxohexyl)-6-(1E)-1-propenyl-, (9aR)- (9CI). Grades: > 95%. CAS No. 514-66-9. Molecular formula: C21H23NO4. Mole weight: 353.42.
Rubropunctatin
A pigment hs more anti-atherosclerosis effect and less side effect involving increasing creatinine phosphokinase activity. Synonyms: 2H-Furo[3,?2-g]?[2]?benzopyran-2,?9(9aH)?-dione, 9a-methyl-3-(1-oxohexyl)?-6-(1E)?-1-propen-1-yl-, (9aR)?-. Grades: > 95%. CAS No. 514-67-0. Molecular formula: C21H22O5. Mole weight: 354.41.
SDMA
SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide ( NO ) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing. Uses: Scientific research. Group: Natural products. Alternative Names: Symmetric dimethylarginine; NG,NG'-Dimethyl-L-arginine. CAS No. 30344-00-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101410.
Sibeprenlimab
Sibeprenlimab (VIS649) is a humanized IgG2 monoclonal antibody which inhibits a proliferation-inducing ligand ( APRIL ). Sibeprenlimab suppresses pathogenic immunoglobulins ( IgA and IgM ), while preserving antibody responses to mRNA-based vaccines against SARS-COV-2. Sibeprenlimab reduces urinary protein-to-creatinine ratio (UPCR) and glomerular filtration rate (GFR). Sibeprenlimab is promising for the research of IgA nephropathy (IgAN) [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: VIS649. CAS No. 2382896-07-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99901.
SLV 320
SLV 320 is a potent and selective adenosine A1 receptor antagonist (Ki = 1, 200, 398 and 3981 nM at human A1, A3, A2A and A2B receptors, respectively). SLV320 prevents nephrectomy-dependent rise in plasma levels of creatinine kinase (CK), ALT and AST. SLV 320 inhibits cardiac fibrosis and attenuates albuminuria, without affecting blood pressure in animal models of chronic renal failure. Synonyms: SLV320; SLV-320; SLV 320; Derenofylline; trans-4-[(2-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclohexanol. Grades: ≥99% by HPLC. CAS No. 251945-92-3. Molecular formula: C18H20N4O. Mole weight: 308.38.
Trichlormethiazide
Trichlormethiazide is an orally active thiazide diuretic, with antihypertensive effect. Trichlormethiazide increases urine volume (UV), Na and K excretion and tends to improve the depressed creatinine clearance (CCRE) in acute renal failure rats model [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 133-67-5. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g; 10 g. Product ID: HY-B0235.
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