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| Product | Description | |
|---|---|---|
| crisaborole | Crisaborole is a novel PDE-4 inhibitor used as a nonsteroidal topical medication for the treatment of mild-to-moderate atopic dermatitis (eczema). Crisaborole selectively inhibits PDE-4B which mainly leads to inflammation. Tumor necrosis factor alpha (TNFα), interleukin-12 (IL-12), IL-23 and other cytokines are also suppressed while crisaborole functioning. Uses: The treatment of mild-to-moderate atopic dermatitis (eczema). Synonyms: AN2728; AN-2728; AN 2728; Crisaborole; Eucrisa; 4-((1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yl)oxy)benzonitrile. Grades: 99%. CAS No. 906673-24-3. Molecular formula: C14H10BNO3. Mole weight: 251.048. |  |
| Crisaborole | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Crisaborole | Crisaborole (AN-2728) is a potent inhibitor of PDE4 and cytokine release; inhibit PDE4 with an IC 50 of 0.49 μM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AN-2728; PF-06930164. CAS No. 906673-24-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10978. |  |
| Crisaborole Impurity 35 | Crisaborole Impurity 35. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,4-dibromo-5-methylphenol. CAS No. 13321-76-1. Molecular formula: C7H6Br2O. Mole weight: 265.93. Catalog: APB13321761. | |
| Crisaborole Impurity 36 | Crisaborole Impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,4-dibromo-3-methylphenol. CAS No. 13321-75-0. Molecular formula: C7H6Br2O. Mole weight: 265.93. Catalog: APB13321750. | |
| Crisaborole M-hydroxybenzaldehyde | Crisaborole M-hydroxybenzaldehyde. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-hydroxybenzaldehyde. CAS No. 100-83-4. Molecular formula: C7H6O2. Mole weight: 122.12. Catalog: APB100834. | |
| Crisaborole (Standard) | Crisaborole (Standard) is the analytical standard of Crisaborole. This product is intended for research and analytical applications. Crisaborole (AN-2728) is a potent inhibitor of PDE4 and cytokine release; inhibit PDE4 with an IC 50 of 0.49 μM. Uses: Scientific research. Group: Signaling pathways. CAS No. 906673-24-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10978R. | |
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