Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| CRT0066101 | CRT0066101 is a potent and orally active PKD inhibitor with IC 50 values of 1 nM, 2.5 nM and 2 nM for PKD1 , PKD2 , and PKD3 , respectively [1]. CRT0066101 is also a potent PIM2 inhibitor with an IC 50 of ~135.7?nM. CRT0066101 exhibits anti-inflammatory activity in mice LPS (HY-D1056)-induced lung injury models, and has anticancer effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 956123-34-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-15698. |  |
| CRT0066101 | CRT0066101 is a small-molecule protein kinase D (PKD) inhibitor that suppresses PDK1, PDK2 and PDK3 (PDK1: IC50 = 1 nM; PDK2: IC50 = 2.5 nM; PDK3: IC50 = 2 nM). Studies in vivo showed that CRT0066101 inhibited pancreatic cancer growth. Synonyms: Phenol, 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-, hydrochloride (1:2); (R)-2-(4-((2-Aminobutyl)amino)pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride; 2-(4-{[(2R)-2-Aminobutyl]amino}pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol dihydrochloride; CRT 0066101; CRT-0066101; CRT0066101 dihydrochloride. Grades: ≥95%. CAS No. 1883545-60-5. Molecular formula: C18H22N6O.2HCl. Mole weight: 411.33. |  |
| CRT0066101 dihydrochloride | CRT0066101 dihydrochloride is a potent and orally active PKD inhibitor with IC 50 values of 1 nM, 2.5 nM and 2 nM for PKD1 , PKD2 , and PKD3 , respectively [1]. CRT0066101 dihydrochloride is also a potent PIM2 inhibitor with an IC 50 of ~135.7?nM. CRT0066101 dihydrochloride exhibits anti-inflammatory activity in mice LPS (HY-D1056)-induced lung injury models, and has anticancer effects [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1883545-60-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-15698A. | |
| CRT0066101 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| CRT0066101 hydrochloride | CRT0066101 is an inhibitor of all three PKD isoforms (IC50s = 1, 2.5, and 2 nM for PKD1, PKD2, and PKD3, respectively). It exhibits selectivity for PKD against a panel of >90 protein kinases, including PKCα, PKBα, MEK, ERK, c-Raf, c-Src, and c-Abl. Synonyms: Phenol, 2-[4-[[(2R)-2-aminobutyl]amino]-2-pyrimidinyl]-4-(1-methyl-1H-pyrazol-4-yl)-, hydrochloride (1:3); (R)-2-(4-((2-Aminobutyl)amino)pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol trihydrochloride; 2-(4-{[(2R)-2-Aminobutyl]amino}pyrimidin-2-yl)-4-(1-methyl-1H-pyrazol-4-yl)phenol trihydrochloride. Grades: ≥95%. CAS No. 1781742-22-0. Molecular formula: C18H22N6O.3HCl. Mole weight: 447.79. | |
Our database is helping our users find suppliers everyday.
