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| Product | Description | |
|---|---|---|
| CRT0066854 | CRT0066854 is a potent and selective atypical PKC isoenzymes inhibitor. CRT0066854 is against full-length (FL) PKCΙ , PKCζ , and ROCK-II kinases with IC 50 values of 132 nM, 639 nM, and 620 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1438881-19-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-18713. |  |
| CRT0066854 | CRT0066854 is a selective and ATP-competitive inhibitor of the atypical PKC isoenzymes (IC50 values 639 nM and 132 nM for full-length PKCζ, PKCΙ, respectively). CRT0066854 decreases colony formation in HeLa cells, inhibits LLGL2 phosphorylation and polarized epithelial morphogenesis, and impedes directed migration of NRK cells. Synonyms: CRT0066854; CRT 0066854; CRT-0066854; (2S)-3-Phenyl-N1-[5,6,7,8-tetrahydro-2-(4-pyridinyl)[1]benzothieno[2,3-d]pyrimidin-4-yl]-1,2-propanediamine. Grades: 99%. CAS No. 1438881-19-6. Molecular formula: C24H25N5S. Mole weight: 415.55. |  |
| CRT0066854 hydrochloride | CRT0066854 hydrochloride is a potent and selective atypical PKC s inhibitor. CRT0066854 is against full-length (FL) PKCΙ , PKCζ , and ROCK-II kinases with IC 50 values of 132 nM, 639 nM, and 620 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2250019-91-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-18713A. | |
| CRT 0066854 hydrochloride | The hydrochloride salt form of CRT 0066854, which has been found to be a PKC inhibitor. Synonyms: CRT 0066854 hydrochloride; CRT0066854 hydrochloride; CRT-0066854 hydrochloride; (2S)-3-Phenyl-N1-[5,6,7,8-tetrahydro-2-(4-pyridinyl)[1]benzothieno[2,3-d]pyrimidin-4-yl]-1,2-propanediamine dihydrochloride. Grades: ≥98% by HPLC. Molecular formula: C24H25N5S.2HCl. Mole weight: 488.48. | |
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