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Product
CTEP ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
CTEP CTEP is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor (IC50=2.2 nM), showing >1000-fold selectivity over other mGlu receptors. Synonyms: RO4956371; RO-4956371; RO 4956371; CTEP. Grades: >98%. CAS No. 871362-31-1. Molecular formula: C19H13ClF3N3O. Mole weight: 391.77. BOC Sciences 10
CTEP CTEP (RO 4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC 50 of 2.2 nM, and shows > 1000-fold selectivity over other mGlu receptors. CTEP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RO 4956371; mGluR5 inhibitor. CAS No. 871362-31-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15445. MedChemExpress MCE
Basimglurant Basimglurant (RG7090) is a potent, selective and orally available mGlu5 negative allosteric modulator with a K d of 1.1 nM [1]. Basimglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RG7090; CTEP Derivative. CAS No. 802906-73-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15446. MedChemExpress MCE
RG7090 RG7090 is a negative modulator of metabotropic glutamate receptor subtype 5 (mGluR5; GRM5). Synonyms: Basimglurant; CTEP Derivative; RG7090; RG 7090; RG-7090. Grades: >98%. CAS No. 802906-73-6. Molecular formula: C18H13ClFN3. Mole weight: 325.77. BOC Sciences 10
Riociguat Riociguat (BAY 63-2521; BAY 632521) is a novel drug that is currently in clinical development by Bayer. At the moment Phase III clinical trials investigate the use of riociguat as a new approach to treat two forms of pulmonary hypertension (PH): chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). Riociguat constitutes the first drug of a novel class of sGC stimulators. Synonyms: BAY 63-2521; BAY63-2521; BAY632521; Riociguat; Brand name: Adempas. Grades: 0.99. CAS No. 625115-55-1. Molecular formula: C20H19FN8O2. Mole weight: 422.424. BOC Sciences 9

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