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| Product | Description | |
|---|---|---|
| 1-[(5E)-3-O-[(Bis-di-isopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil | 1-[(5E)-3-O-[(Bis-di-isopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil is an exceptionally powerful antiviral therapy that has shown remarkable promise in fighting HIV-1 and other retroviral infections. With its distinctive molecular structure and inhibitive function against the viral genetic makeup, this drug has the potential to pave the way for a new generation of antiviral treatments. Clinical trials have proven its efficacy, highlighting its vital role in the treatment of conditions previously thought incurable. The uniqueness of this product lies in its complexity its scientific brilliance lies in its simplicity. Experience the power of science with 1-[(5E)-3-O-[(Bis-di-isopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]-5-methyluracil. Synonyms: 3-[[(2R,3R,4R,5R)-2-[(E)-2-diethoxyphosphorylethenyl]-4-(2-methoxyethoxy)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile. Grade: ≥95%. CAS No. 1345562-47-1. Molecular formula: C27H46N4O10P2. Mole weight: 648.62. |  |
| 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]uracil | 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-(2-methoxyethyl)-β-D-ribo-hex-5-enofuranosyl]uracil - a remarkable pharmaceutical compound known for its potency against viral infections. Deemed an anti-DNA virus agent, this unique product is effective against formidable pathogens like herpes simplex virus (HSV), varicella-zoster virus (VZV), and even the notorious human immunodeficiency virus (HIV). By restraining viral DNA polymerase, it deftly curtails virus replication, ultimately conferring unparalleled therapeutic benefits. Grade: ≥95%. Molecular formula: C26H44N4O10P2. Mole weight: 634.60. | |
| 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phos-phino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil | 1-[(5E)-3-O-[(Bis-diisopropylamino)(2-cyanoethoxy)phos-phino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]uracil, a potent agent for the treatment of human immunodeficiency virus (HIV) infections, functions as a viral replication inhibitor by suppressing the reverse transcriptase enzyme. Its intricate molecular structure reflects the sophisticated nature of modern pharmaceuticals, which require cutting-edge research and development to ultimately undo the feats of viruses and other elusive adversaries. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[(5E)-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-5,6-dideoxy-6-(diethoxyphosphinyl)-2-O-methyl-β-D-ribo-hex-5-enofuranosyl]-. Grade: ≥95%. CAS No. 2361324-80-1. Molecular formula: C24H40N4O9P2. Mole weight: 590.54. | |
| 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-2,4(1H,3H)-pyrimidinedione | 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-2,4(1H,3H)-pyrimidinedione is a vital compound extensively utilized in the field of biomedicine. This product acts as a key reagent in the synthesis of modified nucleotides for research purposes. It is commonly employed in DNA and RNA synthesis, particularly in the development of oligonucleotides for therapeutic interventions targeting various diseases, such as cancer and viral infections. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-deoxy-β-D-threo-pentofuranosyl]-; 5-O-(4,4'-Dimethoxytrityl)-2-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,3-dideoxy-1-uracil-1-yl-beta-D-threo-pentofuranose; (2R,3S,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 3'-ara-dU Phosphoramidite; 5'-O-DMTr-3'-deoxyuridine ara-2'-phosphoramidite. Grade: ≥95%. CAS No. 161503-98-6. Molecular formula: C39H47N4O8P. Mole weight: 730.79. | |
| (1R, 3R, 4R, 7S) -7- (2-Cyanoethoxy (diisopropylamino) phosphinoxy) -1 - (4, 4'-dimethoxytrityloxy methyl ) -3- (thymin-1-yl) -2, 5-dioxa-bicyclo [2. 2. 1] heptane | (1R, 3R, 4R, 7S) -7- (2-Cyanoethoxy (diisopropylamino) phosphinoxy) -1 - (4, 4'-dimethoxytrityloxy methyl ) -3- (thymin-1-yl) -2, 5-dioxa-bicyclo [2. 2. 1] heptane. Group: Biochemicals. Alternative Names: LNA-T-CE Phosphoramidite. Grades: Highly Purified. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences. |  Worldwide |
| (1S, 3R, 4S, 7R) -7- (2-Cyanoethoxy (diisopropylamino) phosphinoxy) -1 - (4, 4'-dimethoxytrityloxy methyl ) -3- (5- methyl -4-N-benzoylcytosine-1-yl) -2, 5-dioxabicyclo [2. 2. 1] heptane | (1S, 3R, 4S, 7R) -7- (2-Cyanoethoxy (diisopropylamino) phosphinoxy) -1 - (4, 4'-dimethoxytrityloxy methyl ) -3- (5- methyl -4-N-benzoylcytosine-1-yl) -2, 5-dioxabicyclo [2. 2. 1] heptane. Group: Biochemicals. Alternative Names: a-L-LNA-Me-Bz-C-CE Phosphoramidite. Grades: Highly Purified. Pack Sizes: 50mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| 2,?4(1H,?3H)?-?Pyrimidinedione, 1-?[5-?O-?[[bis(1-?methylethyl)?amino]?(2-?cyanoethoxy)?phosphino]?-?2,?3-?dideoxy-?2-?fluoro-?3-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?β-?D-?arabinofuranosyl]?-?5-?methyl- | The biochemical 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2,3-dideoxy-2-fluoro-3-[[(4-methoxyphenyl)diphenylmethyl]amino]-β-D-arabinofuranosyl]-5-methyl-, is well known in the biomedical realm due to its anticancer effects, serving as a therapeutic agent for acute myeloid leukemia, chronic lymphocytic leukemia, and non-Hodgkin's lymphoma by impeding DNA synthesis and obstructing the propagation and dissemination of malignant cancerous cells, thereby proving to be an indispensable asset. Synonyms: 2-cyanoethyl (((2S,3R,4R,5R)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)-5-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl) diisopropylphosphoramidite. CAS No. 329773-25-3. Molecular formula: C39H47FN5O6P. Mole weight: 731.79. | |
| ((((2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(1-methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphanyl)dipropylnickel | (2R,3R,4S,5S)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-5-(1-methyl-4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl)oxy)(2-cyanoethoxy)phosphanyl)dipropylnickel is used in the biomedical field to catalyze carbon-carbon bond forming reactions, which are essential in the synthesis of certain drugs utilized for treating cancer and infectious diseases. Molecular formula: C46H63N4O8PSSi. Mole weight: 891.15. | |
| 5-[(2-Cyanoethoxy)methyl]-2'-deoxycytidine | 5-[(2-Cyanoethoxy)methyl]-2'-deoxycytidine, a fascinating molecule of great significance in the realm of biomedicine. Renowned for its exceptional antiviral properties, this compound assumes a pivotal role in the diligent pursuit of pharmaceutical advancements against DNA viruses, including the likes of herpes simplex virus and varicella-zoster virus. Exerting its formidable prowess, it effectively thwarts viral replication, thus warranting consideration as a promising contender for future antiviral therapies. Synonyms: Cytidine, 5-[(2-cyanoethoxy)methyl]-2'-deoxy-; 188411-05-4; 3-[[4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-5-yl]methoxy]propanenitrile. Grade: ≥ 97%. CAS No. 188411-05-4. Molecular formula: C13H18N4O5. Mole weight: 310.31. | |
| Bis(2-cyanoethoxy)-1-(N-t-boc-sphingosine-1-Phosphate-13C2,D2 | Intermediate for a labeled putative lipid second messenger; found to inhibit cellular mobility of melanoma cells at very low concentrati. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| (N4-Benzoyl)-5'-O-[(N,N-Diisopropylamino)-(2-Cyanoethoxy)phosphinyl]-3'-O-(4,4'-Dimethoxytrityl)-2'-Deoxycytidine | (N4-Benzoyl)-5'-O-[(N,N-Diisopropylamino)-(2-Cyanoethoxy)phosphinyl]-3'-O-(4,4'-Dimethoxytrityl)-2'-Deoxycytidine, a sophisticated and multifunctional compound at the forefront of biomedical advancements, encompasses a pivotal role in the realm of biomedicine. It stands as an indispensable agent in the combat against an array of ailments. Synonyms: ((2R,3S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite; Cytidine,N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]. Grade: 95%. CAS No. 140712-83-0. Molecular formula: C46H52N5O9P. Mole weight: 849.91. | |
| (N6-Benzoyl)-5'-O-[(n,N-diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine | (N6-Benzoyl)-5'-O-[(n,N-diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (N6-BENZOYL)-5'-O-[(N,N-DIISOPROPYLAMINO)-(2-CYANOETHOXY)PHOSPHINYL]-3'-O-(4,4'-DIMETHOXYTRITYL)-2'-DEOXYADENOSINE;(N6-BENZOYL)-5''-O-[(N,N-DIISOPROPYLAMINO)-(2-CYANOETHOXY)PHOSPHINYL]-3''-O-(4,4''-DIMETHOXYTRITYL)-2''-DEOXYADENOSINE. Product Category: Heterocyclic Organic Compound. CAS No. 140712-82-9. Molecular formula: C47H52N7O8P. Mole weight: 873.93. Product ID: ACM140712829. Alfa Chemistry ISO 9001:2015 Certified. |  |
| (N6-Benzoyl)-5'-O-[(N,N-diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine | (N6-Benzoyl)-5'-O-[(N,N-diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is a modified phosphoramidite used in oligonucleotide synthesis. This compound includes protective groups such as dimethoxytrityl (DMT), benzoyl (Bz), and cyanoethyl (CE). These protective groups play a crucial role in the synthesis process, ensuring correct assembly and sequence synthesis of nucleotides, particularly in reverse synthesis (from the 5' to 3' end). Synonyms: Adenosine, N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Adenosine, N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N4-benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-5'-cyanoethyl Phosphoramidite; DMT-dA(Bz)-5'-CE Reverse Phosphoramidite; 3'-DMT-dA(Bz)-CE Reverse; 3'-O-DMTr-dA(Bz)-5'-CE-Phosphoramidite; DMT-dA(Bz)-CE Inverted Phosphoramidite; N6-benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine-5'-cyanoethyl Phosphoramidite. Grade: 95%. CAS No. 140712-82-9. Molecular formula: C47H52N7O7P. Mole weight: 857.93. | |
| 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-CE phosphoramidite | 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine 3'-CE phosphoramidite is used in the solid-phase synthesis of modified oligonucleotides. The modifications enhance the stability and binding affinity of the oligonucleotides. These modified nucleotides are valuable in various applications, including the development of antisense oligonucleotides, siRNA, and other therapeutic nucleic acids, as well as in research settings where enhanced stability and specific interactions are required. Synonyms: 5'-O-dimethoxytrityl-2'-deoxy-2'-fluoroarabinothymidine-3'-[(2-cyanoethyl)-(N,N-diisopropropyl)]-Phosphoramidite; 2'-F-ANA-T-3'-CE-Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine-3'-CED-phosphoramidite; 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; 2'-Deoxy-2'-fluoro-5-Me-ara-U-3'-CED-phosphoramidite. Grade: 97%. CAS No. 208193-48-0. Molecular formula: C40H48FN4O8P. Mole weight: 762.82. | |
| 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE-phosphoramidite | 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)uracil 3'-CE-phosphoramidite is a novel nucleotide monophosphate with antiviral and anticancer properties. Synonyms: 2'-Fluoro-2'-deoxy-ara-U-3'-phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-2'-fluoro-b-D-arabinouridine-3'-CEN-phosphoramidite; 5'-O-DMT-2'-F-2'-arabinofuranosyl-deoxyuridine 3'-CE phosphoramidite; 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-α-D-arabinofuranosyl]-; 2'-ara-2'-F-2'-dU Phosphoramidite; 2'-F-U-ANA-CE Phosphoramidite. Grade: ≥95%. CAS No. 1190089-70-3. Molecular formula: C39H46FN4O8P. Mole weight: 748.78. | |
| 1-Me-dA-CE Phosphoramidite | 1-Me-dA-CE Phosphoramidite, an essential resource in the realm of biomedical research, holds particular significance in the field of DNA synthesis and modification. Its primary purpose lies in integrating 1-Methyladenine (1-Me-dA) modifications into nucleic acid sequences. Its unblemished purity and adaptability to diverse synthesizers empower scientists to effectuate meticulous modifications, fueling the investigation of DNA-protein interactions, epigenetics, and DNA repair mechanisms. Synonyms: 5'-Monomethoxytrityl-N6-chloroacetyl-1-methyl-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-[9-[3-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5-O-(4-methoxytrityl)-2-deoxy-beta-D-ribofuranosyl]-1-methyl-1,6-dihydro-9H-purine-6-ylidene]chloroacetamide. Molecular formula: C42H49ClN7O6P. Mole weight: 814.31. | |
| 2-Aminopurine riboside CEP | 2-Aminopurine riboside CEP, an indispensable chemical entity extensively utilized within the biomedical sector, serves as a nucleoside analog. Its application predominantly revolves around the investigation and advancement of antiviral therapeutics designed to combat RNA virus-induced infections. Synonyms: N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-9H-purin-2-yl]-2-methylpropanamide; Phosphoramidous acid, bis(1-methylethyl)-, mono(2-cyanoethyl) ester, ester with N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-9H-purin-2-yl]-2-methylpropanamide; 2-Aminopurine-TBDMS-CE Phosphoramidite; 5'-Dimethoxytrityl-N2-isobutyryl-2-aminopurine riboside, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2-Amino Purine Riboside CED phosphoramidite. CAS No. 151059-65-3. Molecular formula: C50H68N7O8PSi. Mole weight: 954.18. | |
| 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphordiamidite | 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphordiamidite. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Cetipd, 305995_ALDRICH, CID128153, ZINC02539453, Bis(diisopropylamino)(2-cyanoethoxy)phosphine, 2-Cyanoethyl N,N,N,N-tetraisopropylphosphordiamidite, 2-Cyanoethyl tetrakis(1-methylethyl)phosphorodiamidoate, 2-Cyanoethyl-N,N,N,N-tetraisopropylphosphorodiamidite, 102691-36-1, Phosphorodiamidous acid, tetrakis(1-methylethyl)-, 2-cyanoethyl ester. Appearance: colorless to yellow clear liquid. CAS No. 102691-36-1. Molecular formula: C15H32N3OP. Mole weight: 301.41. Purity: 94%+. IUPACName: 3-bis[di(propan-2-yl)amino]phosphanyloxypropanenitrile. Canonical SMILES: CC(C)N(C(C)C)P(N(C(C)C)C(C)C)OCCC#N. Density: 0.949. ECNumber: 600-337-9. Product ID: ACM102691361. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite | 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite is a chemical compound used in the synthesis of oligonucleotides. It serves as a phosphoramidite building block, facilitating the addition of nucleotide units during solid-phase oligonucleotide synthesis. The cyanoethyl group protects the phosphorus atom, while the tetraisopropylphosphorodiamidite moiety enables efficient coupling reactions with nucleotides. This reagent plays a crucial role in the automated synthesis of oligonucleotides, allowing for the controlled assembly of DNA or RNA sequences with high purity and yield. Synonyms: N,N,N',N'-Tetrakis(1-methylethyl)phosphorodiamidous Acid 2-Cyanoethyl Ester; 2-Cyanoethoxy bis(N,N-diisopropylamino)phosphine; 2-Cyanoethyl Tetraisopropylphosphorodiamidite; Bis(diisopropylamino)(2-cyanoethoxy)phosphine; 3-((Bis(diisopropylamino)phosphino)oxy)propanenitrile. Grade: ≥95%. CAS No. 102691-36-1. Molecular formula: C15H32N3OP. Mole weight: 301.41. | |
| 2-Cyanoethyl phosphorodichloridite | 2-Cyanoethyl phosphorodichloridite. Group: Biochemicals. Alternative Names: (2-Cyanoethoxy) dichlorophosphine; Phosphorodichloridous acid 2-cyanoethyl ester. Grades: Highly Purified. CAS No. 76101-30-9. Pack Sizes: 5g. Molecular Formula: C3H4NOPCl2. US Biological Life Sciences. | Worldwide |
| 2-Cyanoethyl tetraisopropyl phosphorodiamidite | 2-Cyanoethyl tetraisopropyl phosphorodiamidite. Group: Biochemicals. Alternative Names: Bis (diisopropylamino) (2-cyanoethoxy)phosphine. Grades: Highly Purified. CAS No. 102691-36-1. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C15H32N3OP. US Biological Life Sciences. | Worldwide |
| 2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite | 2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-propynyl]-uridine 3'-CE phosphoramidite is a highly intricate and cutting-edge phosphoramidite derivative, manifesting immense potential in the realm of biomedical applications. Synonyms: 5-TFA-ap-dU phosphoramidite; alpha-[2-(Trifluoroacetylamino)ethylidyne]-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)thymidine; Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-[3-[(2,2,2-trifluoroacetyl)amino]-1-propyn-1-yl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-5-{3-[(trifluoroacetyl)amino]-1-propyn-1-yl}uridine. Grade: ≥98% by HPLC. CAS No. 120016-98-0. Molecular formula: C44H49F3N5O9P. Mole weight: 879.86. | |
| 2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite | 2'-Deoxy-5'-O-DMT-5-iodouridine 3'-CE phosphoramidite is a crucial component in the biomedicine industry. It is employed for the synthesis of modified oligonucleotides with potent therapeutic potential. By incorporating this phosphoramidite, the resulting oligonucleotides display enhanced drug efficacy against specific diseases, such as cancer, viral infections, or genetic disorders. This product serves as a valuable tool for researchers and pharmaceutical companies striving to develop innovative nucleotide-based therapies. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-5-iodo-2'-deoxyuridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphorramidite; 5-Iodo-dU-3'-phosphoramidite; 5'-O-DMTr-5-iodo-2'-dU-3'-CED phosphoramidite; 5-I-dU-CE Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-5-iodouridine; 5-Iodo-dU CEP. Grade: 97%. CAS No. 178925-48-9. Molecular formula: C39H46IN4O8P. Mole weight: 856.69. | |
| 2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite | 2'-Deoxy-5'-O-DMT-N4-Fmoc-5-methylcytidine 3'-CE-phosphoramidite, an indispensable biochemical reagent, finds extensive application in the synthesis of modified nucleosides for groundbreaking biomedical research. Its usage is pivotal in the quest for novel drugs and therapies that target specific ailments, including cancer and viral infections. Additionally, this product's significance permeates the realm of nucleic acid chemistry, enabling researchers to delve into the intricacies of DNA and RNA modifications, thereby augmenting drug effectiveness and improving disease detection techniques. Synonyms: BP-40031; 5'-O-DMTr-N4-Fmoc-5-Me-dC-phosphoramidite; (9H-Fluoren-9-yl)methyl (1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate; (9H-Fluoren-9-yl)methyl(1-((2R,4S,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphino)oxy)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)carbamate; 9H-Fluoren-9-ylmethyl N-[1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]-5-methyl-2-oxopyrimidin-4-yl]carbamate. CAS No. 176755-87-6. Molecular formula: C55H60N5O9P. Mole weight: 966.1. | |
| 2'-deoxypseudoU-CE Phosphoramidite | 2'-deoxypseudoU-CE Phosphoramidite is a paramount asset in the biomedical realm, enables the intricate research and development of modified oligonucleotides. The seamless integration of this compound into nucleic acids bestows upon researchers a platform to scrutinize the impact of altered nucleotides on pharmaceutical attributes and pathological pathways. Synonyms: 2'-Deoxy-5'-O-DMT-pseudouridine 3'-CE phosphoramidite; 2'-Deoxypseudouridine CEP; 5'-O-DMT-2'-deoxypseudouridine 3'-CE phosphoramidite; 5-[3-O-[Diisopropylamino(2-cyanoethoxy)phosphino]-5-O-(4,4'-dimethoxytrityl)-2-deoxy-beta-D-erythro-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione; (1R)-1,4-Anhydro-5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-1-(2,4-dioxo-1,2,3,4-tetrahydro-5-pyrimidinyl)-D-erythro-pentitol. Grade: 95%. CAS No. 289712-98-7. Molecular formula: C39H47N4O8P. Mole weight: 730.8. | |
| 2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite | 2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a modified phosphoramidite used in the synthesis of oligonucleotides. This compound features a 2'-fluoro and 2'-deoxy modification on the arabinose sugar, a benzoyl (Bz) protective group on the nucleobase cytosine, and a phosphoramidite group at the 3' position. These modifications enhance the chemical stability and binding affinity of the resulting oligonucleotides, making them useful for applications in molecular biology, diagnostics, and therapeutic development. Synonyms: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-b-D-arabinocytidine-3'-CED-phosphoramidite; N4-Benzoyl-2'-fluoro-5'-O-DMT-2'-arabinofuranosyl-deoxycytidine phosphoramidite; 4-(Benzoylimino)-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-1,4-dihydro-2-pyrimidinol; N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytidine 3'-CE-phosphoramidite; 5'-O-DMTr-2'-ara-F-C(Bz)-3'-CE-Phosphoramidite; 2'-F-2'-ara-Bz-dC Phosphoramidite; 2'-F-dC(Bz)-ANA-CE Phosphoramidite; 2'-F-2'-ara-N4-Bz-dC phosphoramidite. Grade: ≥95%. CAS No. 1404463-12-2. Molecular formula: C46H51FN5O8P. Mole weight: 851.90. | |
| 2-Isobutyrylamino-9-(2'-O-tert-butyldimethylsilyl-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite | 2-Isobutyrylamino-9-(2'-O-tert-butyldimethylsilyl-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite is an essential component in oligonucleotide synthesis for the biomedical industry. It is used in the modification and synthesis of nucleotide sequences targeting specific genes or diseases. Its unique properties allow for efficient and accurate incorporation into DNA and RNA strands, enabling researchers to study and develop therapeutic interventions for various conditions. Synonyms: 2'-OTBS 2-amino(iBu)purine amidite; N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-9H-purin-2-yl]butanamide. Grade: >95%. CAS No. 179558-91-9. Molecular formula: C50H68N7O8PSi. Mole weight: 954.20. | |
| 2'-O-Acetyl-N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)arabinocytidine 3'-O-phosphoramidite | 2'-O-Acetyl-N4-benzoyl-5'-O-(4,4'-dimethoxytrityl)arabinocytidine 3'-O-phosphoramidite, a fundamental compound in oligonucleotide synthesis, plays a vital role in the advancement of diagnostic tools and therapeutic drugs within the biomedical field. Synonyms: DMTr-2'-ara-OAc-C(Bz)-3'-CE-Phosphoramidite; N-[1-[2-O-Acetyl-5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-β-D-arabinofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide; (2R,3S,4R,5R)-2-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-3-yl acetate; N4-benzoyl-(5'-O-(4,4'-dimethoxytrityl)-2'-O-acetyl-arabinocytidine-3'-[(2-cyanoethyl)-(N,N-diisopropropyl)]-Phosphoramidite; 5'-O-DMTr-2'-ara-OAc-C(Bz)-3'-CE-Phosphoramidite; Cytosine Arabinoside. Grade: ≥95%. CAS No. 675573-97-4. Molecular formula: C48H54N5O10P. Mole weight: 891.94. | |
| 2'-O-Methyl-pyrrolo C CEP | 2'-O-Methyl-pyrrolo C CEP is a fluorescent analog of cytidine and a highly fluorescent proven to be useful for monitoring RNA secondary structure formation, where its fluorescence is reversibly quenched upon base-pairing. Synonyms: 3-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-1,3-dihydro-6-methyl-2H-pyrrolo[2,3-d]pyrimidin-2-one. CAS No. 644962-95-8. Molecular formula: C43H52N5O8P. Mole weight: 797.88. | |
| 2'-O-Propargyl G(iBu)-3'-phosphoramidite | 2'-O-Propargyl G(iBu)-3'-phosphoramidite is a vital compound extensively used in the field of biomedicine. This compound acting as a versatile building block for the synthesis of modified nucleosides and oligonucleotides. It finding applications in the development of therapeutic compounds, particularly for the reserch of viral infections and genetic diseases. Synonyms: N2-iBu-5'-O-DMTr-2'-O-propargylguanosine-3'-CED-phosphoramidite; N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-propargyl guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite; 5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-N-(2-methyl-1-oxopropyl)?-2'-O-2-propynyl-guanosine 3'-[2-cyanoethyl bis(1-methylethyl)?phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-2-propyn-1-ylguanosine; DMTr-2'-O-propargyl-rG(iBu)-3'-CE-Phosphoramidite; 5'-O-DMT-2'-O-Propargyl-N2-isobutyryl-Guanosine 3'-CE phosphoramidite; N2-iBu-DMT-2'-O-propargyl-G-CE-Phosphoramidite; 2'-O-propargyl Guanosine (n-ibu) CED phosphoramidite. Grade: ≥95%. CAS No. 171486-61-6. Molecular formula: C47H56N7O9P. Mole weight: 893.96. | |
| 2'-O-tert-Butyldimethylsilyl-5-O-DMT-nebularine 3'-CE phosphoramidite | 2'-O-tert-Butyldimethylsilyl-5-O-DMT-nebularine 3'-CE phosphoramidite is a cutting-edge substance harboring extraordinary potential, catalyzing the research and development of tailored oligonucleotides, augmenting the efficiency and precision of nucleic acid sequence alterations. Synonyms: 9-(2'-O-tert-Butyldimethylsilyl-5'-O-DMT-b-D-ribofuranosyl)purine 3'-CE phosphoramidite; 2'-OTBS Purine amidite; 9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-9H-purine; Nebularine 3''-CE phosphoramidite; Purine Riboside CED phosphoramidite. Grade: >95%. CAS No. 151132-95-5. Molecular formula: C46H61N6O7PSi. Mole weight: 869.07. | |
| 3-Butoxypropionitrile | 3-Butoxypropionitrile. Group: Battery materials electronic materials. Alternative Names: 1-(2-Cyanoethoxy)butane. CAS No. 6959-71-3. Product ID: 3-butoxypropanenitrile. Molecular formula: 127.19. Mole weight: C7H13NO. CCCCOCCC#N. InChI=1S / C7H13NO / c1-2-3-6-9-7-4-5-8 / h2-4, 6-7H2, 1H3. AWVNJBFNHGQUQU-UHFFFAOYSA-N. >96.0%(GC). |  |
| 3-Deaza-3-methyl-dA CEP | 3-Deaza-3-methyl-dA CEP, a pivotal compound within the biomedicine realm, boasts indispensability. Its principal application resides in the amalgamation of DNA analogs and the adjustment of nucleosides, serving as a catalyst for cutting-edge investigations. By assuming a critical role in anti-viral drug development and genetic disease analysis, this product furnishes invaluable perspectives on diverse therapeutic interventions. Synonyms: Benzamide, N-benzoyl-N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-beta-D-erythro-pentofuranosyl]-7-methyl-1H-imidazo[4,5-c]pyridin-4-yl]-; DTXSID001098448; N-Benzoyl-N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-beta-D-erythro-pentofuranosyl]-7-methyl-1H-imidazo[4,5-c]pyridin-4-yl]benzamide. CAS No. 1031750-37-4. Molecular formula: C56H59N6O8P. Mole weight: 975.08. | |
| 3'-F-3'-dA(Bz)-2'-phosphoramidite | 3'-F-3'-dA(Bz)-2'-phosphoramidite, an indispensable compound widely employed in the biomedical sector for the synthesis of oligonucleotides and nucleic acid analogs, holds paramount importance. Its modified structure renders it adept at enhancing stability, selectivity, and binding properties. Synonyms: N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-deoxy-3'-fluoroadenosine-2'-CED-phosphoramidite; N-[9-[(2R,3S,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-4-fluorooxolan-2-yl]purin-6-yl]benzamide; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-3'-deoxy-3'-fluoroadenosine; 5'-DMT-3'-fluoro-DA(BZ) amidite; 3'-F A(Bz) 2'-amidite. Grade: ≥95%. CAS No. 2127174-09-6. Molecular formula: C47H51FN7O7P. Mole weight: 875.92. | |
| 3'-O-(4,4'-Dimethoxytrityl)-thymidine-5'-cyanoethyl-Phosphoramidite | 3'-O-(4,4'-Dimethoxytrityl)-thymidine-5'-cyanoethyl-Phosphoramidite is a phosphoramidite used in the synthesis of oligonucleotides. It is specifically designed for use in automated oligonucleotide synthesis systems, ensuring precise and controlled addition of thymidine units in the synthesis of custom DNA sequences. Synonyms: 5'-O-[(Diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)thymidine; DMT-dT-CE Inverted Phosphoramidite; 3'-O-(4,4'-Dimethoxytrityl)-thymidine-5'-cyanoethyl Phosphoramidite; Thymidine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Thymidine, 3'-O-[bis(4-methoxyphenyl)phenylmethyl]-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥98%. CAS No. 134031-86-0. Molecular formula: C40H49N4O8P. Mole weight: 744.81. | |
| 3'-O-DMT-5-Methy-Uridine-TNA 2'-CE phosphoramidite | 3'-O-DMT-5-Methy-Uridine-TNA 2'-CE phosphoramidite stands as a fundamental ingredient for the in vitro selection of aptamers; RNA molecules designed for the specific capturing of target molecules, including drugs and disease biomarkers. Synthesized using this crucial element, these aptamers have enormous potential for application in both drug discovery and diagnostics research fields. Synonyms: DMTr-TNA-5MeU-amidite; 1-[(2R)-3alpha-[(Diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]thymine; T-TNA Phosphoramidite. Grade: 98%. CAS No. 325683-94-1. Molecular formula: C39H47N4O8P. Mole weight: 730.80. | |
| 3'-O-DMT-N6-Benzoyl-Adenosine TNA 2'-CE phosphoramidite | 3'-O-DMT-N6-Benzoyl-Adenosine TNA 2'-CE phosphoramidite is a modified nucleotide used in the synthesis of Threose Nucleic Acid (TNA) molecules for biomedical research. TNA is a promising alternative to DNA and RNA for gene and drug delivery due to its chemical stability and resistance to nuclease degradation. This specific phosphoramidite derivative incorporates a benzoyl-adenosine moiety, making it ideal for designing TNA-based drugs for the treatment of viral infections, inflammatory diseases, and cancer. Synonyms: DMTr-TNA A(Bz)-amidite; TNA-A(Bz)-CE-Phosphoramidite; DMTr-TNA A(Bz)-Phosphoramidite; N-Benzoyl-9-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]-9H-purine-6-amine; 1-{2'-O-[(2-Cyanoethoxy)(diisopropyl amino)phosphino]-3'-O-[(4,4'-dimethoxytriphenyl)methyl]-a-L-threofuranosyl}-N6-benzoyladenine; (2R,3R,4S)-2-[6-(Benzoylamino)-9H. Grade: 98%. CAS No. 325683-93-0. Molecular formula: C46H50N7O7P. Mole weight: 843.92. | |
| 3'-O-DMT-N6-Benzoyl-Cytidine TNA 2'-CE phosphoramidite | TNA 2'-CE oligonucleotide synthesis necessitates 3'-O-DMT-N6-benzoyl-cytidine, and our TNA 2'-CE phosphoramidite is precisely engineered for just that purpose. Researchers within the biomedicine discipline rely heavily on our product due to their capacity to incorporate TNA monomers as they fabricate artificial nucleic acids for gene-based therapeutics and pharmacological advancement. Synonyms: Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[4-(benzoylamino)-2-oxo-1(2H)-pyrimidinyl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; DMTr-TNA C(Bz)-amidite; (2R,3R,4S)-2-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; TNA-C(Bz)-CE-Phosphoramidite; N-Benzoyl-1-[(2R)-3alpha-[(diisopropylamino)(2-cyanoethoxy)phosphinooxy]-4beta-(4,4'-dimethoxytrityloxy)tetrahydrofuran-2beta-yl]cytosine; DMTr-TNA-C(Bz)-Phosphoramidite. Grade: 98%. CAS No. 325683-96-3. Molecular formula: C45H50N5O8P. Mole weight: 819.90. | |
| 3'-O-DMT-O6-DPC-N2-Acetyl-Guanosine TNA 2'-CE phosphoramidite | 3'-O-DMT-O6-DPC-N2-Acetyl-Guanosine TNA 2'-CE phosphoramidite is a highly complex chemical compound utilized in the biomedical industry to fabricate nucleic acid-based drugs that effectively combat a multitude of ailments, including but not limited to cancer, viral infections, and genetic disorders. The intricate nature of the molecule allows for the synthesis of oligonucleotides that specifically target variably expressed genes, culminating in an unparalleled approach towards achieving precision medication. Procuring this compound necessitates a specialized skill set and equipment, and can only be obtained from esteemed chemical outlets. Synonyms: DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite; TNA-G(O-CONPh2)(N-Ac)CE-Phosphoramidite; Phosphoramidous acid, bis(1-methylethyl)-, (2R,3R,4S)-2-[2-(acetylamino)-6-[[(diphenylamino)carbonyl]oxy]-9H-purin-9-yl]-4-[bis(4-methoxyphenyl)phenylmethoxy]tetrahydro-3-furanyl 2-cyanoethyl ester; 2-Acetamido-9-((2R,3R,4S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl diphenylcarbamate. Grade: 98%. CAS No. 325683-97-4. Molecular formula: C54H57N8O9P. Mole weight: 993.05. | |
| 4-O-Acetyl-2,5-anhydro-1,3-O-isopropylidene-6-[bis(2-cyanoethyl)phosphoryl]-D-glucitol | 4-O-Acetyl-2,5-anhydro-1,3-O-isopropylidene-6-[bis(2-cyanoethyl)phosphoryl]-D-glucitol, an extensively explored compound in biomedicine, exhibits remarkable promise for therapeutic interventions.The intricate molecular architecture and distinctive properties of this compound contribute significantly to its value as an indispensable constituent in biomedical research. Synonyms: 4-O-Acetyl-2,5-anhydro-1,3-O-isopropylidene-6-[bis(2-cyanoethyl)phosphoryl]-D-glucitol; [(4aS,6R,7S,7aS)-6-[bis(2-cyanoethoxy)phosphoryloxymethyl]-2,2-dimethyl-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3]dioxin-7-yl] acetate; AKOS030241006; J-001106. CAS No. 1041021-85-5. Molecular formula: C17H25N2O9P. Mole weight: 432.36. | |
| 5-Br-rU Phosphoramidite | 5-Br-rU Phosphoramidite, a vital constituent in biomedical research and drug development, finds utility as a building block for oligonucleotide union and holds immense potential in therapies for diseases like cancer and viral infections. Notably, owing to its distinctive chemical features, it can tinker with the structure and function of nucleic acids, facilitating precise treatment, and improved delivery of medications. Synonyms: Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-bromo-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-5-bromo-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]uridine; 5-Bromo-2'-O-tert-butylbutyldimethylsilyl-5'-O-DMT-D-uridine 3'-CE phosphoramidite; Br-U-CE Phosphoramidite; 5-Bromo Uridine CED phosphoramidite; 5-Bromo 2'-TBDMS Uridine 3'-CE phosphoramidite; DMTr-2'-O-TBDMS-5-Br-rU-3'-CE-Phosphoramidite. Grade: ≥97% by HPLC. CAS No. 166733-98-8. Molecular formula: C45H60BrN4O9PSi. Mole weight: 939.96. | |
| 5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite | 5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite is a phosphoramidite derivative used in the synthesis of modified oligonucleotides for biomedical research. It enables the incorporation of 2'-O-methyl-pseudouridine modifications into RNA sequences, enhancing stability and specific RNA-protein interactions. Synonyms: 2'-O-Methyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; pseudoUridine (with 5'-DMT, 3'-phosphoramidite, and 2'-OMe); 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione. Grade: ≥95% by HPLC. CAS No. 199737-09-2. Molecular formula: C40H49N4O9P. Mole weight: 760.81. | |
| 5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite | It is a modified ribonucleoside analogue suitable for incorporation into small interfering RNA (siRNA) to enhance RNA stability in biological applications such as gene silencing. Synonyms: 5'-Dimethoxytrityl-1-methyl-pseudouridine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5-[5-O-[bis(4-methoxyphenyl)?phenylmethyl]?-3-O-[[bis(1-methylethyl)?amino]?(2-cyanoethoxy)?phosphino]?-2-O-[(1,?1-dimethylethyl)?dimethylsilyl]?-β-D-ribofuranosyl]?-1-methyl-2,?4(1H,?3H)?-pyrimidinedione; 2'-O-TBDMS-N1-Me-Pseudouridine CEP; 5'-O-DMTr-2'-O-TBDMS-N1-methylpseudouridine 3'-(cyanoethyl-N,N-diisopropyl)phosphoramidite; 5'-O-DMT-2'-O-TBDMS-N1-Me-pU Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-N1-methyl-Pseudouridine-3'-cyanoethyl Phosphoramidite. Grade: ≥98%. CAS No. 875302-45-7. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite | 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite is a valuable compound primarily employed for the research and development of RNA molecules required for diagnostic purposes or therapeutic interventions. This compound plays a crucial role in the development of drugs targeting specific diseases and disorders, such as cancers or viral infections. It facilitates efficient nucleotide incorporation and ensures accurate development of RNA sequences. Synonyms: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; PseudoUridine-CE Phosphoramidite; Pseudouridine CEP; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-beta-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione; 5'-O-DMTr-2'-O-TBDMS-Pseudouridine-3'-CE Phosphoramidite; 5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-Pseudouridine-3'-cyanoethyl-Phosphoramidite. Grade: ≥95%. CAS No. 163496-23-9. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05. | |
| 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite | 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite, a highly valued compound within the biomedicine sector, plays a pivotal role in the synthetic production of altered nucleic acids. Primarily employed as a fundamental unit during oligonucleotide formation, it showcases tremendous potential in advancing RNA-based therapeutic interventions. Through its exceptional capability, this product empowers precise and effective nucleoside modification, enabling targeted remedies for an array of prevalent ailments including viral afflictions and hereditary anomalies. Synonyms: 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine 2'-Phosphoramidite; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1-methyl-2,4(1H,3H)-pyrimidinedione; (2S,3S,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-2-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥95%. CAS No. 875302-47-9. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| 5'-DMT-3'-O-TBDMS-PseudoUridine-CE-Phosphoramidite | 5'-DMT-3'-O-TBDMS-PseudoUridine-CE-Phosphoramidite, an indispensable compound in the thriving biomedical sector, serves as a pivotal component for oligonucleotide synthesis. This ground-breaking technique unlocks unparalleled potential to combat a myriad of afflictions encompassing cancer, viral infections, and genetic aberrations. Synonyms: 5'-DMT-3'-O-TBDMS-PseudoUridine 2'-Phosphoramidite; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-3-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione; (2S,3S,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)-2-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite. Grade: ≥95%. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05. | |
| 5'-DMT-NHS-Carboxy dU 3'-Phosphoramidite | 5'-DMT-NHS-Carboxy dU 3'-Phosphoramidite is a phosphoramidite compound used in the synthesis of oligonucleotides. It is designed to incorporate a modified deoxyuridine nucleotide into DNA strands, which can enhance the stability and functionality of the synthesized oligonucleotides. This compound is used to improve the metabolic stability and binding affinity of the synthesized oligonucleotides, making them more suitable for specific biological applications such as gene regulation, and antisense therapy. Synonyms: N-Hydroxysuccinimide carboxy-dT phosphoramidite; 2-Propenoic acid, 3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 3-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl]-2-propenoate; NHS-Carboxy-dT; 5'-Dimethoxytrityl-5-[3-acrylate NHS ester]-2'-deoxyUridine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5'-DMT-5-NHS-carboxy-2'-deoxy-rU 3'-Phosphoramidite. CAS No. 1354695-41-2. Molecular formula: C46H52N5O12P. Mole weight: 897.91. | |
| 5-Ethylcarboxy-dC(Bz) Phosphoramidite | 5-Ethylcarboxy-dC(Bz) Phosphoramidite is a modified phosphoramidite where the cytosine base is functionalized with an ethylcarboxy group at the 5-position and protected with a benzoyl (Bz) group on the exocyclic amine. The sugar moiety is designed with a 3'-phosphoramidite functionality for compatibility with automated DNA synthesis. This compound is commonly used to introduce chemically modified cytosine residues into oligonucleotides, enabling studies on DNA-protein interactions, epigenetic modifications, and the effects of base alterations on nucleic acid stability and function. It is particularly useful in therapeutic oligonucleotide development and molecular biology research. Synonyms: 5-Pyrimidinecarboxylic acid, 4-(benzoylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-, ethyl ester; 5-Carboxy-dC-CE Phosphoramidite; 5'-Dimethoxytrityl-N-benzoyl-5-ethylcarboxy-2'-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; DNA 5-carbethoxy-C(Bz) amidite. Grade: ≥95%. CAS No. 1535202-71-1. Molecular formula: C49H56N5O10P. Mole weight: 905.97. | |
| 5'-GalNAc C3 Phosphoramidite | 5'-GalNAc C3 Phosphoramidite is a specialized reagent used in oligonucleotide synthesis to introduce N-acetylgalactosamine (GalNAc) at the 5'-end of the oligonucleotide sequence. GalNAc is a carbohydrate moiety commonly found in glycoproteins and glycolipids and is involved in various biological processes, including cell signaling and immune response modulation. By attaching GalNAc to oligonucleotides, researchers can develop molecular probes and therapeutics targeting specific carbohydrate-binding proteins, such as lectins and receptors. This modification enables the study of carbohydrate-protein interactions and the development of oligonucleotide-based drugs for therapeutic applications, including gene regulation, RNA interference, and targeted delivery. Synonyms: Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl [1-[1-oxo-6-[[1-oxo-4-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]butyl]amino]hexyl]-4-[[tris(4-methoxyphenyl)methoxy]methyl]-4-piperidinyl]methyl ester; (2R,3R,4R,5R,6R)-5-Acetamido-2-(acetoxymethyl)-6-(4-((6-(4-((((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)methyl)-4-((tris(4-methoxyphenyl)methoxy)methyl)p. Grade: >98%. CAS No. 2437303-51-8. Molecular formula: C62H88N5O17P. Mole weight: 1206.36. | |
| 5-Hydroxy-DC cep | 5-Hydroxy-DC cep is an extraordinary bioactive compound, having the ability to meticulously target and repress malignant cells by thwarting pivotal pathways mediated by anomalous enzymes and receptors. Synonyms: N-Benzoyl-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-5-(benzoyloxy)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine. Grade: 95%. CAS No. 197579-70-7. Molecular formula: C53H56N5O10P. Mole weight: 954. | |
| 5-Hydroxymethyl-dC II-CE Phosphoramidite | 5-Hydroxymethyl-dC II-CE Phosphoramidite, a frequently employed reagent in genomic research, is indispensable for synthesizing modified oligonucleotides. Its site-specific labeling aptitude benefits the subsequent detection and analysis of DNA and RNA strands. Besides, the application of 5-Hydroxymethyl-dC II-CE Phosphoramidite in anti-cancer and anti-HIV therapies development also renders it an integral tool in the medical field. Synonyms: 5'-Dimethoxytrityl-5-hydroxymethyl-N,O-carbamoyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N,5-(Carbonyloxymethylene)-3'-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine. CAS No. 1257247-42-9. Molecular formula: C41H48N5O9P. Mole weight: 785.82. | |
| 5-Nitroindole 3'-CE phosphoramidite | 5-Nitroindole 3'-CE Phosphoramidite is a modified phosphoramidite used in the synthesis of oligonucleotides with specific functional modifications. The 5-nitroindole component refers to an indole ring structure that is functionalized with a nitro group at the 5-position, which introduces electron-withdrawing properties that can influence the oligonucleotide's interaction with other molecules, such as nucleic acids or proteins. The nitroindole modification may enhance the stability, reactivity, or specificity of the oligonucleotide for particular applications. This phosphoramidite is useful in synthesizing oligonucleotides for applications in research involving fluorescence-based detection, molecular interactions, or RNA interference. The nitroindole modification may also offer advantages in terms of increased stability or enhanced binding properties for therapeutic applications, such as gene silencing or antisense oligonucleotides. Synonyms: 1-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-5-nitro-1H-indole; 5-Nitroindole-CE phosphoramidite; 5'-Dimethoxytrityl-2'-deoxy-5-nitroindole-ribofuranosyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; DNA 5-NO2-indole amidite. Grade: ≥96%. CAS No. 911823-92-2. Molecular formula: C43H49N4O8P. Mole weight: 780.86. | |
| 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-3-formylindole-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxy-3-formylindole-ribofuranosyl-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite, a compound widely employed in biomedicine, exhibits extraordinary versatility. It serves as an essential phosphoramidite building block during the synthesis of modified oligonucleotides, thereby holding immense potential in fields like antisense therapeutics, gene therapy, and molecular diagnostics. Synonyms: 5-Formylindole-CE Phosphoramidite; 1H-Indole-3-carboxaldehyde, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-. Grade: ≥95%. CAS No. 460355-05-9. Molecular formula: C44H50N3O7P. Mole weight: 763.86. | |
| 5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite | 5'-O-DMT-2'-deoxyuridine-3'-CE Phosphoramidite stands as an indispensable entity within the realm of biomedicine, wherein its applications for the synthesis of nucleic acids in investigative capacities hold paramount significance. DNA and RNA oligonucleotides rely on this product as their cornerstone, as it seamlessly integrates 2'-deoxyuridine into nucleic acid sequences with exacting efficiency. Aiding the progression of pharmaceutical innovation, gene therapy, and genetic exploration, it emerges as an invaluable instrument that propels advancements in the remediation of diverse medical afflictions. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; 2'-Deoxy-5'-O-DMT-uridine 3'-CE Phosphoramidite; DMT-dU Phosphoramidite; 5-O-(4,4'-dimethoxytrityl)-3-O-(diisopropylamino-2-cyanoethoxyphosphanyl)-1,2-dideoxy-1-uracil-1-yl-beta-D-erythro-pentofuranose; 3'-O-[(Diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyuridine. Grade: ≥95%. CAS No. 109389-30-2. Molecular formula: C39H47N4O8P. Mole weight: 730.80. | |
| 5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-(2-methoxyethyl)uridine 3'-CE phosphoramidite is a building block for introducing uridine units into oligonucleotides. Synonyms: 2'-O-MOE-U-3'-phosphoramidite; 5'-O-DMTr-2'-O-(2-methoxyethyl)-uridine-3'-CED-phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)uridine. Grade: ≥95%. CAS No. 163759-97-5. Molecular formula: C42H53N4O10P. Mole weight: 804.86. | |
| 5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite is a phosphoramidite reagent used to introduce 2-O-methyl modified U nucleotide into oligonucleotides. Synonyms: 5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 2'-Deoxy-2'-O-Me-5'-O-DMT-Uridine-3'-CED Phosphoramidite; 2'-OMe-U-CEP; 5'-Dimethoxytrityl-Uridine, 2'-O-methyl, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2'-O-Methyl-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)uridine. Grade: ≥95%. CAS No. 110764-79-9. Molecular formula: C40H49N4O9P. Mole weight: 760.81. | |
| 5'-O-DMT-2'-O-TBDMS-L-Uridine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-L-Uridine 3'-CE phosphoramidite, a highly versatile and indispensable compound within the biomedical industry, occupies a paramount position in the synthesis of oligonucleotides of immense significance. Blending seamlessly with various applications including gene therapy, nucleic acid-based diagnostics, and drug development, this invaluable marvel propels the progress of medical science. Its inherent ability to modify nucleotide sequences bestows unmatched stability and facilitates target-specific drug conveyance, fostering advancements in the treatment of multifarious diseases, encompassing cancer and genetic disorders. Synonyms: 2,4(1H,3H)-Pyrimidinedione, 1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-; 1-[2-O-(tert-Butyldimethylsilyl)-3-O-[diisopropylamino(2-cyanoethoxy)phosphino]-5-O-(4,4'-dimethoxytrityl)-beta-L-ribofuranosyl]uracil; DMT-2'-O-TBDMS-L-rU Phosphoramidite; L-RNA 2'-OTBS U amidite; 5'-O-DMT-2'-O-TBDMS-L-U 3'-CE phosphoramidite. Grade: ≥98% by HPLC. CAS No. 144490-31-3. Molecular formula: C45H61N4O9PSi. Mole weight: 861.06. | |
| 5'-O-DMT-2'-O-TBDMS-N2-isobutyryl-L-Guanosine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-N2-isobutyryl-L-Guanosine 3'-CE phosphoramidite, a sophisticated compound integral to the production of custom oligonucleotides, showcases remarkable versatility. It serves as a phosphoramidite foundation during solid-phase DNA synthesis, facilitating the integration of guanosine modifications. By harnessing this product, nucleic acid researchers can probe gene expression or delve into the impact of guanosine alterations on ailments such as cancer. Synonyms: DMT-2'-O-TBDMS-L-rG(ibu) Phosphoramidite; N-[9-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-2-methylpropanamide; L-rG(ibu) Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-G(iBu)-3'-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-guanosine-3'-cyanoethyl Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 679809-76-8. Molecular formula: C50H68N7O9PSi. Mole weight: 970.19. | |
| 5'-O-DMT-2'-O-TBDMS-N4-Acetyl-L-Cytidine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-N4-Acetyl-L-Cytidine 3'-CE phosphoramidite, a remarkable substance within the biomedical field, holds immense significance. Its application in the synthesis of altered oligonucleotides for therapeutic intentions is widespread. Through the specific manipulation and addressing of genetic material, particularly RNA, it exhibits a pivotal role in combating diverse ailments. Boasting an exceptional composition, this product possesses the power to revolutionize precision medicine and propel the progression of targeted therapies. Synonyms: Acetamide, N-[1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-; DMT-2'-O-TBDMS-L-rC(Ac) Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 237060-94-5. Molecular formula: C47H64N5O9PSi. Mole weight: 902.11. | |
| 5'-O-DMT-2'-O-TBDMS-N6-Benzoyl-L-Adenosine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-TBDMS-N6-Benzoyl-L-Adenosine 3'-CE phosphoramidite is a crucial reagent used in the synthesis of oligonucleotides for biomedical research. It enables the efficient introduction of N6-benzoyl-L-Adenosine residues into the oligonucleotide chain, thus allowing the study of adenosine-modified nucleic acids. This product finds applications in drug discovery, gene therapy, and understanding diseases related to adenosine signaling pathways. Synonyms: Benzamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-β-L-ribofuranosyl]-9H-purin-6-yl]-; N-Benzoyl-9-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-O-[dimethyl(2-methyl-2-propanyl)silyl]-β-L-ribofuranosyl}-9H-purin-6-amine; DMT-2'-O-TBDMS-L-rA(Bz) Phosphoramidite; 5'-O-DMTr-2'-O-TBDMS-L-A(Bz)-3'-CE-Phosphoramidite; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-L-adenosine-3'-cyanoethyl Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 1803193-36-3. Molecular formula: C53H66N7O8PSi. Mole weight: 988.21. | |
| 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-Inosine 3'-CE phosphoramidite | Antiviral and anticancer drug for cells infected with influenza A virus, herpes simplex virus type 2, and human lymphocytic leukemia cells. Synonyms: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-inosine 3'-CE phosphoramidite; 2'-O-(tert-Butyldimethylsilyl)-3'-O-[(diisopropylamino)(2-cyanoethoxy)phosphino]-5'-O-(4,4'-dimethoxytrityl)inosine; Inosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]inosine; DMT-2'-O-TBDMS-I-CE-Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-2'-O-(t-butyldimethylsilyl)-inosine-3'-cyanoethyl Phosphoramidite. Grade: ≥97% by HPLC. CAS No. 261518-12-1. Molecular formula: C46H61N6O8PSi. Mole weight: 885.07. | |
| 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N2-isobutyrylguanosine 3'-CE phosphoramidite is a classic protected 2-OTBDMS phosphoramidite used for incorporating ribo-G into synthetic oligonucleotides. Synonyms: 5'-O-(4,4-Dimethoxytrityl)-2'-O-[(tert-butyl)dimethylsilyl]-N-isobutyrylguanosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite; iBu-rG CE phosphoramidite; DMT-2'-O-TBDMS-rG(iBu) Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]-N-isobutyrylguanosine; 5'-O-DMT-2'-O-TBDMS-N2-Isobutyryl-Guanosine-CE Phosphoramidite; 2'-TBDMS-ibu-G-CE-Phosphoramidite; DMT-2'-O-TBDMS-G(iBu)-CE-Phosphoramidite; N2-Isobutyryl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-guanosine-3'-cyanoethyl Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 147201-04-5. Molecular formula: C50H68N7O9PSi. Mole weight: 970.18. | |
| 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-methyl-adenosine 3'-CE phosphoramidite | 5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-methyl-adenosine 3'-CE phosphoramidite is a vital compound used in the biomedical industry for synthesizing RNA molecules. This phosphoramidite aids in the incorporation of modified adenosine bases during RNA synthesis, enabling researchers to study specific drug targets or diseases related to N6-methyladenosine methylation. By providing precise adenosine modifications, this product facilitates the investigation of gene expression and regulatory mechanisms, leading to potential breakthroughs in drug discovery and disease understanding. Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-methyl-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N6-Me-rA phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-[dimethyl(2-methyl-2-propanyl)silyl]-N-methyladenosine; N6-Me-DMT-2'-O-TBDMS-A-CE Phosphoramidite; N6-Methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(t-butyl-dimethylsilyl)-adenosine-3'-cyanoethyl-Phosphoramidite; 5'-O-DMT-2'-O-TBDMS-N6-methyl-Adenosine 3'-CE phosphoramidite; DMTr-2'-O-TBDMS-N6-Me-rA-3'-CE-Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 588698-79-7. Molecular formula: C47H64N7O7PSi. Mole weight: 898.11. | |
| 5'-O-DMT-3'-O-TBDMS-N6-Benzoyl-Adenosine 2'-CE phosphoramidite | 5'-O-DMT-3'-O-TBDMS-N6-Benzoyl-Adenosine 2'-CE phosphoramidite is an antiviral nucleoside phosphoramidite for DNA synthesis. Synonyms: N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 3'-TBDMS-Bz-rA Phosphoramidite; N-Benzoyl-2'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-3'-O-(tert-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)adenosine; N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(t-butyldimethylsilyl)-adenosine-2'-cyanoethyl phosphoramidite; 5'-O-DMTr-3'-O-TBDMS-A(Bz)-2'-CE-Phosphoramidite; N6-benzoyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-(t-butyl-dimethylsilyl)-adenosine-2'-cyanoethyl Phosphoramidite. Grade: ≥95%. CAS No. 129451-75-8. Molecular formula: C53H66N7O8PSi. Mole weight: 988.19. | |
| 5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite | 5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a crucial tool in the research and development of modified oligonucleotides. It facilitates the incorporation of the 5'-O-DMT-5-Ethynyl-2'-deoxyuridine nucleotide into the desired sequence during solid-phase research and development. This phosphoramidite derivative finds applications in drug discovery, therapeutics and molecular biology, aiding in the research of nucleic acid analogs for various diseases. Synonyms: N-Benzoyl-5-((2-cyanoethoxy)methyl)-2'-deoxycytidine CEP; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-[(2-cyanoethoxy)methyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-[(2-cyanoethoxy)methyl]-2'-deoxy-3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]cytidine. Grade: ≥95% by HPLC. CAS No. 188411-06-5. Molecular formula: C50H57N6O9P. Mole weight: 917.00. | |
| 5'-O-DMT-N2-isobutyryl-2'-O-?methoxyethylguanosine 3'-CE phosphoramidite | 5'-O-DMT-N2-isobutyryl-2'-O-methoxyethylguanosine 3'-CE phosphoramidite is used to incorporate 2'-O-methoxyethyl-modified G into oligonucleotides, which is useful for antisense RNA. Synonyms: 5'-O-DMTr-N2-iBu-2'-O-MOE-guanosine-3'-CED phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N2-iso-butyroyl-2'-O-(2-methoxyethyl)guanosine-3'-O-[(2-cyanoethyl)(N,N-diisopropyl)]phosphoramidite; 2'-MOE-G(iBu)-3'-phosphoramidite; DMT-2M-O-Me-rG(ib) amidite; N2-isobutyryl-5'-O-DMT-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite; N-Isobutyryl-2'-O-(2-methoxyethyl)-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)guanosine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-N-isobutyryl-2'-O-(2-methoxyethyl)guanosine. Grade: ≥95%. CAS No. 251647-55-9. Molecular formula: C47H60N7O10P. Mole weight: 913.99. | |
| 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-arabinofuranosyl-deoxycytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-arabinofuranosyl-deoxycytidine 3'-CE phosphoramidite is a crucial reagent extensively used in the biomedical industry for the synthesis of nucleosides and nucleotides. This product plays a significant role in the development of therapeutic drugs targeting various diseases, including viral infections and cancer. With its unique properties, it enables researchers to design and fabricate novel nucleoside analogs with potential antiviral and anticancer activities, contributing to advancements in biomedicine. Synonyms: 2'-F-2'-ara-Ac-dC Phosphoramidite; 4-Acetamido-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-2(1H)-pyrimidinone; 2(1H)-Pyrimidinone, 4-(acetylamino)-1-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-; N-Acetyl-5'-O-(4,4-dimethoxytrityl)-2'-deoxy-2'-fluorocytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grade: ≥97% by HPLC. Molecular formula: C41H49FN5O8P. Mole weight: 789.83. | |
| 5'-O-DMT-N4-Benzoyl-5-Methy-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-5-Methy-2'-O-(2-methoxyethyl)cytidine 3'-CE phosphoramidite is used to incorporate methyl-C modified with 2'-O-methoxyethyl into oligonucleotides, which is useful for anti-sense RNA. Synonyms: N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine 3'-CE phosphoramidite; 2'-O-MOE-N4-Bz-5-Me-C Phosphoramidite; 5-Me-DMT-2'-O-MOE-C(Bz)-CEP; N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methoxyethyl-cytidine-3'-cyanoethyl phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-O-(2-methoxyethyl)-5-methyl-3,4-dihydrocytidine; 5'-O-DMT-2'-O-MOE-MeC(Bz) 3'-CE phosphoramidite. Grade: ≥98% by HPLC. CAS No. 163759-94-2. Molecular formula: C50H60N5O10P. Mole weight: 922.01. | |
| 5'-O-DMT-N4-Benzoyl-5-methyl-2'-O-methylcytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-5-methyl-2'-O-methylcytidine 3'-CE phosphoramidite is a phosphoramidite analogue with antiviral, anticancer and antimalarial properties. Synonyms: N4-Benzoyl-5-methyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-methyl-cytidine-3'-cyanoethyl phosphoramidite; 2'-OMe-N6-Bz-5-Me-C Phosphoramidite; 5'-DMT-N4-Bz-2'-OMe-5-Me-C phosphoramidite; DMT-2'-OME-dC(Bz)-CE-Phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-5-methyl-2'-O-methylcytidine; 5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite; 5'-O-DMT-2'-O-Me-MeC(Bz)-3'-CE-Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 166593-57-3. Molecular formula: C48H56N5O9P. Mole weight: 877.98. | |
| 5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite | 5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite, a chemical reagent widely employed in oligonucleotide synthesis for biomedical research, manifests remarkable versatility in targeting a wide range of ailments, spanning from cancer to genetic disorders. With its ready availability and proven efficacy in in-vitro experiments, this chemical reagent is the go-to choice for generating novel and effective therapeutic oligonucleotides. Synonyms: IBU-DC Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-N-isobutyrylcytidine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-deoxy-N-(2-methylpropanoyl)cytidine; N-Isobutyryl-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine; IBU-dC CEP. Grade: ≥98% by HPLC. CAS No. 110522-84-4. Molecular formula: C43H54N5O8P. Mole weight: 799.90. | |
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