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| Product | Description | |
|---|---|---|
| 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase | This multiunctional enzyme catalyses both the removal of nicotinamide from NADP+, forming 2'-phospho-cyclic ADP-ribose, and the addition of nicotinate to the cyclic product, forming NAADP+, a calcium messenger that can mobilize intracellular Ca2+ stores and activate Ca2+ influx to regulate a wide range of physiological processes. In addition, the enzyme also catalyses EC 3.2.2.6, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase. Group: Enzymes. Synonyms: diphosphopyridine nucleosidase (ambiguous); CD38 (gene name); BST1 (gene name). Enzyme Commission Number: EC 2.4.99.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2705; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; EC 2.4.99.20; diphosphopyridine nucleosidase (ambiguous); CD38 (gene name); BST1 (gene name). Cat No: EXWM-2705. |  |
| 5'-oxoaverantin cyclase | Isolated from the aflatoxin-producing mold Aspergillus parasiticus. The enzyme also catalyses the conversion of versiconal to versicolorin B (EC 4.2.1.143, versicolorin B synthase). Involved in aflatoxin biosynthesis. Group: Enzymes. Synonyms: OAVN cyclase; 5'-oxoaverantin hydro-lyase [(2'S,5'S)-averufin forming]. Enzyme Commission Number: EC 4.2.1.142. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4983; 5'-oxoaverantin cyclase; EC 4.2.1.142; OAVN cyclase; 5'-oxoaverantin hydro-lyase [(2'S,5'S)-averufin forming]. Cat No: EXWM-4983. | |
| adenylate cyclase | Also acts on dATP to form 3',5'-cyclic dAMP. Requires pyruvate. Activated by NAD+ in the presence of EC 2.4.2.31 NAD(P)+-arginine ADP-ribosyltransferase. Group: Enzymes. Synonyms: adenylylcyclase; adenyl cyclase; 3',5'-cyclic AMP synthetase; ATP diphosphate-lyase (cyclizing). Enzyme Commission Number: EC 4.6.1.1. CAS No. 9012-42-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5348; adenylate cyclase; EC 4.6.1.1; 9012-42-4; adenylylcyclase; adenyl cyclase; 3',5'-cyclic AMP synthetase; ATP diphosphate-lyase (cyclizing). Cat No: EXWM-5348. | |
| ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase | This multiunctional enzyme catalyses both the synthesis and hydrolysis of cyclic ADP-ribose, a calcium messenger that can mobilize intracellular Ca2+ stores and activate Ca2+ influx to regulate a wide range of physiological processes. In addition, the enzyme also catalyses EC 2.4.99.20, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase. cf. EC 3.2.2.5, NAD+ glycohydrolase. Group: Enzymes. Synonyms: NAD+ nucleosidase; NADase (ambiguous); DPNase (ambiguous); DPN hydrolase (ambiguous); NAD hydrolase (ambiguous); nicotinamide adenine dinucleotide nucleosidase (ambiguous); NAD glycohydrolase (misleading); NAD nucleosidase (ambiguous); nicotinamide adenine dinucleotide glycohydrolase (misleading); CD38 (. Enzyme Commission Number: EC 3.2.2.6. CAS No. 9032-65-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3988; ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase; EC 3.2.2.6; 9032-65-9; NAD+ nucleosidase; NADase (ambiguous); DPNase (ambiguous); DPN hydrolase (ambiguous); NAD hydrolase (ambiguous); nicotinamide adenine dinucleotide nucleosidase (ambiguous); NAD glycohydrolase (misleading); NAD nucleosidase (ambiguous); nicotinamide adenine dinucleotide glycohydrolase (misleading); CD38 (gene name); BST1 (gene name). Cat No: EXWM-3988. | |
| aklanonic acid methyl ester cyclase | The enzyme is involved in the biosynthesis of aklaviketone, an intermediate in the biosynthetic pathways leading to formation of several anthracycline antibiotics, including aclacinomycin, daunorubicin and doxorubicin. Group: Enzymes. Synonyms: dauD (gene name); aknH (gene name); dnrD (gene name); methyl aklanonate cyclase; methyl aklanonate-aklaviketone isomerase (cyclizing); aklaviketone lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5624; aklanonic acid methyl ester cyclase; EC 5.5.1.23; dauD (gene name); aknH (gene name); dnrD (gene name); methyl aklanonate cyclase; methyl aklanonate-aklaviketone isomerase (cyclizing); aklaviketone lyase (decyclizing). Cat No: EXWM-5624. | |
| allene-oxide cyclase | Allene oxides formed by the action of EC 4.2.1.92 hydroperoxide dehydratase, are converted into cyclopentenone derivatives. Group: Enzymes. Enzyme Commission Number: EC 5.3.99.6. CAS No. 118390-59-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5514; allene-oxide cyclase; EC 5.3.99.6; 118390-59-3. Cat No: EXWM-5514. | |
| β-selinene cyclase | Initial cyclization gives (+)-germacrene A in an enzyme bound form which is not released to the medium. Group: Enzymes. Enzyme Commission Number: EC 4.2.3.66. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5227; β-selinene cyclase; EC 4.2.3.66. Cat No: EXWM-5227. | |
| carboxy-cis,cis-muconate cyclase | This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. This enzyme participates in benzoate degradation via hydroxylation. Group: Enzymes. Synonyms: 3-carboxymuconate cyclase; 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.5. CAS No. 37318-55-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5631; carboxy-cis,cis-muconate cyclase; EC 5.5.1.5; 37318-55-1; 3-carboxymuconate cyclase; 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate lyase (decyclizing). Cat No: EXWM-5631. | |
| cytidylate cyclase | This enzyme belongs to the family of lyases, specifically the class of phosphorus-oxygen lyases. Group: Enzymes. Synonyms: 3',5'-cyclic-CMP synthase; cytidylyl cyclase; cytidyl cyclase; CTP diphosphate-lyase (cyclizing). Enzyme Commission Number: EC 4.6.1.6. CAS No. 65357-82-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5356; cytidylate cyclase; EC 4.6.1.6; 65357-82-6; 3',5'-cyclic-CMP synthase; cytidylyl cyclase; cytidyl cyclase; CTP diphosphate-lyase (cyclizing). Cat No: EXWM-5356. | |
| D-glutamate cyclase | Also acts on various derivatives of D-glutamate. Group: Enzymes. Synonyms: D-glutamate hydro-lyase (cyclizing). Enzyme Commission Number: EC 4.2.1.48. CAS No. 37290-80-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5037; D-glutamate cyclase; EC 4.2.1.48; 37290-80-5; D-glutamate hydro-lyase (cyclizing). Cat No: EXWM-5037. | |
| diadenylate cyclase | Cyclic di-3',5'-adenylate is a bioactive molecule produced by some bacteria and archaea, which may function as a secondary signalling molecule.The intracellular bacterial pathogen Listeria monocytogenes secretes it into the host's cytosol, where it triggers a cytosolic pathway of innate immunity. Group: Enzymes. Synonyms: cyclic-di-AMP synthase; dacA (gene name); disA (gene name). Enzyme Commission Number: EC 2.7.7.85. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3298; diadenylate cyclase; EC 2.7.7.85; cyclic-di-AMP synthase; dacA (gene name); disA (gene name). Cat No: EXWM-3298. | |
| diguanylate cyclase | A GGDEF-domain-containing protein that requires Mg2+ or Mn2+ for activity. The enzyme can be activated by BeF3, a phosphoryl mimic, which results in dimerization. Dimerization is required but is not sufficient for diguanylate-cyclase activity. Cyclic di-3',5'-guanylate is an intracellular signalling molecule that controls motility and adhesion in bacterial cells. It was first identified as having a positive allosteric effect on EC 2.4.1.12, cellulose synthase (UDP-forming). Group: Enzymes. Synonyms: DGC; PleD. Enzyme Commission Number: EC 2.7.7.65. CAS No. 146316-82-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3276; diguanylate cyclase; EC 2.7.7.65; 146316-82-7; DGC; PleD. Cat No: EXWM-3276. | |
| Diguanylate Cyclase from Agrobacterium vitis, recombinant | The diguanylate cyclase from Agrobacterium vitis has been engineered to remove phosphodiesterase activity, allowing for production of cyclic-diGMP from guanosine triphosphate (GTP) without the production of 5'-phosphoguanylyl-(3',5')-guanosine (pGpG). Applications: Useful for producing cyclic-digmp from gtp without production of pgpgcompletely lacks unwanted phosphodiesterase activityno product inhibition even at high concentrations of gtpremains active while immobilized to solid resin and retain enzymatic activity after several months of storagecan be used to synthesize radiolabeled cyclic digmp from radiolabeled gtp. Group: Enzymes. Synonyms: DGC; PleD; EC 2.7.7.65; 146316-82-7; Engineered Diguanylate Cyclase. Enzyme Commission Number: EC 2.7.7.65. CAS No. 146316-82-7. Purity: >99% based on SDS-PAGE analysis with coomassie blue. Mole weight: 56 kDa. Activity: 7.5 nmol min-1. Storage: at -80 °C; Multiple freeze/thaw cycles are not recommended. Form: Liquid. Source: E. coli. Species: Agrobacterium vitis. Diguanylate cyclase; DGC; PleD; EC 2.7.7.65; 146316-82-7; Engineered Diguanylate Cyclase. Cat No: NATE-1692. | |
| drimenol cyclase | Drimenol cyclase (EC 3.1.7.7, farnesyl pyrophosphate:drimenol cyclase) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphohydrolase (drimenol-forming). Group: Enzymes. Synonyms: farnesyl pyrophosphate:drimenol cyclase. Enzyme Commission Number: EC 3.1.7.7. CAS No. 146838-17-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3767; drimenol cyclase; EC 3.1.7.7; 146838-17-7; farnesyl pyrophosphate:drimenol cyclase. Cat No: EXWM-3767. | |
| GTP 3',8-cyclase | The enzyme catalyses an early step in the biosynthesis of the molybdenum cofactor (MoCo). In bacteria and plants the reaction is catalysed by MoaA and Cnx2, respectively. In mammals it is catalysed by the MOCS1A domain of the bifunctional MOCS1 protein, which also catalyses EC 4.6.1.17, cyclic pyranopterin monophosphate synthase. The enzyme belongs to the superfamily of radical S-adenosyl-L-methionine (radical SAM) enzymes, and contains two oxygen-sensitive FeS clusters. Group: Enzymes. Synonyms: MOCS1A (gene name); moaA (gene name); cnx2 (gene name). Enzyme Commission Number: EC 4.1.99.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4935; GTP 3',8-cyclase; EC 4.1.99.22; MOCS1A (gene name); moaA (gene name); cnx2 (gene name). Cat No: EXWM-4935. | |
| guanylate cyclase | Also acts on ITP and dGTP. Group: Enzymes. Synonyms: guanylyl cyclase; guanyl cyclase; GTP diphosphate-lyase (cyclizing). Enzyme Commission Number: EC 4.6.1.2. CAS No. 9054-75-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5355; guanylate cyclase; EC 4.6.1.2; 9054-75-5; guanylyl cyclase; guanyl cyclase; GTP diphosphate-lyase (cyclizing). Cat No: EXWM-5355. | |
| Guanylate cyclase-IN-1 | Guanylate cyclase-IN-1 (Example 46) is a guanylate cyclase inhibitor that can be used for cardiovascular diseases research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1361569-23-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W021162. |  |
| lycopene β-cyclase | The enzyme is a non-redox flavoprotein, containing FADH2 that is used for stabilization of a transition state. Lycopene has a ψ-end group at both ends. When acting on one end, the enzyme forms γ-carotene. When acting on both ends it forms β-carotene. It also acts on neurosporene to give β-zeacarotene. Group: Enzymes. Synonyms: CrtL; CrtL-b; CrtY; LCYb; carotenoid β-end group lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.19. CAS No. 220801-82-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5620; lycopene β-cyclase; EC 5.5.1.19; 220801-82-1; CrtL; CrtL-b; CrtY; LCYb; carotenoid β-end group lyase (decyclizing). Cat No: EXWM-5620. | |
| lycopene ε-cyclase | The carotenoid lycopene has the ψ-end group at both ends. When acting on one end, this enzyme forms Δ-carotene. When acting on both ends, it forms ε-carotene. Group: Enzymes. Synonyms: CrtL-e; LCYe; carotenoid ψ-end group lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.18. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5619; lycopene ε-cyclase; EC 5.5.1.18; CrtL-e; LCYe; carotenoid ψ-end group lyase (decyclizing). Cat No: EXWM-5619. | |
| magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase | Requires Fe(II) for activity. The cyclase activity in Chlamydomonas reinhardtii is associated exclusively with the membranes, whereas that from cucumber cotyledons requires both membrane and soluble fractions for activity. Group: Enzymes. Synonyms: Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase. Enzyme Commission Number: EC 1.14.13.81. CAS No. 92353-62-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0889; magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase; EC 1.14.13.81; 92353-62-3; Mg-protoporphyrin IX monomethyl ester (oxidative) cyclase. Cat No: EXWM-0889. | |
| nogalonic acid methyl ester cyclase | The enzyme, characterized from the bacterium Streptomyces nogalater, is involved in the biosynthesis of the aromatic polyketide nogalamycin. Group: Enzymes. Synonyms: methyl nogalonate cyclase; SnoaL (gene name); methyl nogalonate lyase (cyclizing). Enzyme Commission Number: EC 5.5.1.26. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5627; nogalonic acid methyl ester cyclase; EC 5.5.1.26; methyl nogalonate cyclase; SnoaL (gene name); methyl nogalonate lyase (cyclizing). Cat No: EXWM-5627. | |
| olivetolic acid cyclase | Part of the cannabinoids biosynthetic pathway in the plant Cannabis sativa. Group: Enzymes. Synonyms: OAC. Enzyme Commission Number: EC 4.4.1.26. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5328; olivetolic acid cyclase; EC 4.4.1.26; OAC. Cat No: EXWM-5328. | |
| PACAP-27, Amide, Sheep (Pituitary Adenylate Cyclase Activating Polypeptide, HSDGIFTDSYSRYRKQMAVKKy l AAVL-NH2) | Increases cAMP levels in a dose-dependent manner (EC50=4.7nM). Increases tyrosine hydroxylase expression in chromaffin cells.CAS No:127317-03-7. Group: Biochemicals. Grades: Highly Purified. CAS No. 127317-03-7. Pack Sizes: 0.5mg. Molecular Formula: C???H???N??O??S, Molecular Weight: 3147.7. US Biological Life Sciences. |  Worldwide |
| purine imidazole-ring cyclase | Also acts on 2,6-diamino-5-formamido-3,4-dihydro-4-oxopyrimidine residues. Brings about the reclosure of the imidazole rings of purine residues damaged by γ-rays. Group: Enzymes. Synonyms: DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing); DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing; DNA-adenine-forming). Enzyme Commission Number: EC 4.3.2.4. CAS No. 95990-28-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5299; purine imidazole-ring cyclase; EC 4.3.2.4; 95990-28-6; DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing); DNA-4,6-diamino-5-formamidopyrimidine 8-C,9-N-lyase (cyclizing; DNA-adenine-forming). Cat No: EXWM-5299. | |
| RNA 3'-terminal-phosphate cyclase (ATP) | Adenosine 5'-(γ-thio)triphosphate can act instead of ATP. cf. EC 6.5.1.5, RNA-3'-phosphate cyclase (GTP). Group: Enzymes. Synonyms: RNA cyclase (ambiguous); RNA-3'-phosphate cyclase (ambiguous). Enzyme Commission Number: EC 6.5.1.4. CAS No. 85638-41-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5823; RNA 3'-terminal-phosphate cyclase (ATP); EC 6.5.1.4; 85638-41-1; RNA cyclase (ambiguous); RNA-3'-phosphate cyclase (ambiguous). Cat No: EXWM-5823. | |
| RNA 3'-terminal-phosphate cyclase (GTP) | The enzyme from the archaeon Pyrococcus furiosus is activated by Mg2+. cf. EC 6.5.1.4, RNA-3'-phosphate cyclase (ATP). Group: Enzymes. Synonyms: Pf-Rtc; RNA-3'-phosphate cyclase (GTP). Enzyme Commission Number: EC 6.5.1.5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5824; RNA 3'-terminal-phosphate cyclase (GTP); EC 6.5.1.5; Pf-Rtc; RNA-3'-phosphate cyclase (GTP). Cat No: EXWM-5824. | |
| squalene-hopanol cyclase | The enzyme produces the cyclization products hopene (cf. EC 5.4.99.17) and hopanol from squalene at a constant ratio of 5:1. Group: Enzymes. Synonyms: squalene-hopene cyclase (ambiguous). Enzyme Commission Number: EC 4.2.1.129. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4970; squalene-hopanol cyclase; EC 4.2.1.129; squalene-hopene cyclase (ambiguous). Cat No: EXWM-4970. | |
| squalene-hopene cyclase | The enzyme also produces the cyclization product hopan-22-ol by addition of water (cf. EC 4.2.1.129, squalene hopanol cyclase). Hopene and hopanol are formed at a constant ratio of 5:1. Group: Enzymes. Enzyme Commission Number: EC 5.4.99.17. CAS No. 76600-69-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5556; squalene-hopene cyclase; EC 5.4.99.17; 76600-69-6. Cat No: EXWM-5556. | |
| tetracenomycin F2 cyclase | The enzyme is involved in biosynthesis of the anthracycline antibiotic tetracenomycin C by the bacterium Streptomyces glaucescens. Group: Enzymes. Synonyms: tcmI (gene name). Enzyme Commission Number: EC 4.2.1.154. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4995; tetracenomycin F2 cyclase; EC 4.2.1.154; tcmI (gene name). Cat No: EXWM-4995. | |
| tocopherol cyclase | The enzyme has been described from plants and cyanobacteria. It has similar activity with all four listed benzoquinol substrates. Involved in the biosynthesis of vitamin E (tocopherols and tocotrienols). Group: Enzymes. Synonyms: VTE1 (gene name); SXD1 (gene name); Δ/γ-tocopherol lyase (decyclizing). Enzyme Commission Number: EC 5.5.1.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5625; tocopherol cyclase; EC 5.5.1.24; VTE1 (gene name); SXD1 (gene name); Δ/γ-tocopherol lyase (decyclizing). Cat No: EXWM-5625. | |
| 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile | 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile is used in various studies of stimulators of soluble guanylate cyclase. Group: Biochemicals. Grades: Highly Purified. CAS No. 256376-65-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H9FN4. US Biological Life Sciences. | Worldwide |
| 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride | 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboximidamide Hydrochloride is a key intermediate in the synthesis of Riociguat, a potent, oral stimulator of soluble guanylate cyclase for the treatment of pulmonary hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 256499-19-1. Pack Sizes: 250mg, 500mg. Molecular Formula: C14H13ClFN5. US Biological Life Sciences. | Worldwide |
| 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid Ethyl Ester | 1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxylic Acid Ethyl Ester is used in various studies of stimulators of soluble guanylate cyclase. Group: Biochemicals. Grades: Highly Purified. CAS No. 256376-59-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C16H14FN3O2. US Biological Life Sciences. | Worldwide |
| 1-?[ (3-Fluorophenyl) ?methyl]?-1H-?pyrazolo[3, ?4-?b]?pyridine-?3-?carboximidamide | 1-?[ (3-Fluorophenyl) ?methyl]?-1H-?pyrazolo[3, ?4-?b]?pyridine-?3-?carboximidamide is a useful reactant in preparation of pyrrolopyrimidinone derivatives as soluble guanylate cyclase activators. Group: Biochemicals. Grades: Highly Purified. CAS No. 2101651-50-5. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C14H12FN5, Molecular Weight: 269.279999999999. US Biological Life Sciences. | Worldwide |
| 1,8-cineole synthase | Requires Mn2+ or Zn2+. Mg2+ is less effective than either. 1,8-Cineole is the main product from the enzyme with just traces of other monoterpenoids. The oxygen atom is derived from water. The reaction proceeds via linalyl diphosphate and α-terpineol, the stereochemistry of both depends on the organism. However neither intermediate can substitute for geranyl diphosphate. The reaction in Salvia officinalis (sage) proceeds via (-)-(3R)-linalyl diphosphate while that in Arabidopsis (rock cress) proceeds via (+)-(3S)-linalyl diphosphate. Group: Enzymes. Synonyms: 1,8-cineole cyclase; geranyl pyrophoshate:1,8-cineole cyclase; 1,8-cineole synthetase. Enzyme Commission Number: EC 4.2.3.108. CAS No. 110637-19-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5119; 1,8-cineole synthase; EC 4.2.3.108; 110637-19-9; 1,8-cineole cyclase; geranyl pyrophoshate:1,8-cineole cyclase; 1,8-cineole synthetase. Cat No: EXWM-5119. | |
| 1,9-Dideoxyforskolin | 1,9-Dideoxyforkskolin does not activate adenylyl cyclase and is an inactive analog of Forskolin, a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP. Group: Biochemicals. Grades: Highly Purified. CAS No. 64657-18-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C22H34O5, Molecular Weight: 378.5. US Biological Life Sciences. | Worldwide |
| 1-Deoxyforskolin | 1-Deoxyforskolin is active against HIVNL4-3. It also activates mammalian membranous adenylyl cyclase (AC) isoforms I-VIII. Group: Biochemicals. Grades: Highly Purified. CAS No. 72963-77-0. Pack Sizes: 500ug, 1mg. Molecular Formula: C22H34O6. US Biological Life Sciences. | Worldwide |
| 1H-[1,2,4]Oxadiazolo[4,3-a]quinoxalin-1-one | 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one inhibits neurite outgrowth and causes neurite retraction in PC12 cells independently of soluble guanylyl cyclase. Group: Biochemicals. Alternative Names: ODQ. Grades: Highly Purified. CAS No. 41443-28-1. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 2- (1- (2-Fluorobenzyl) -1H-pyrazolo[3, 4-b]pyridin-3-yl) -5- (phenyldiazenyl) pyrimidine-4, 6-diamine | 2- (1- (2-Fluorobenzyl) -1H-pyrazolo[3, 4-b]pyridin-3-yl) -5- (phenyldiazenyl) pyrimidine-4, 6-diamine is a metabolite of stimulators of soluble guanylate cyclase for the treatment of pulmonary hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 428854-23-3. Pack Sizes: 1g, 2.5g. Molecular Formula: C23H18FN9, Molecular Weight: 439.45. US Biological Life Sciences. | Worldwide |
| 2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine | 2-[1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidine-4,5,6-triamine is a metabolite of stimulators of soluble guanylate cyclase for the treatment of pulmonary hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 428854-24-4. Pack Sizes: 50mg, 100mg. Molecular Formula: C17H15FN8. US Biological Life Sciences. | Worldwide |
| 2',5'-Dideoxy adenosine | 2',5'-Dideoxy adenosine is a nucleoside analog that is one of the first identified cell-permeable, P-site inhibitors of adenylate cyclase. It inhibits forskolin-induced activation of a cAMP-dependent reporter gene in HEK293 cells with an IC50 value of 33 μM. Synonyms: 2?,5?-dd-Ado; (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-methyloxolan-3-ol. Grades: ≥98%. CAS No. 6698-26-6. Molecular formula: C10H13N5O2. Mole weight: 235.2. |  |
| 2-Cl-ATP | 2-Cl-ATP is an agonist of P2Y purinoceptor that inhibits soluble guanylate cyclase. Synonyms: 2- Chloroadenosine- 5'- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 49564-60-5. Molecular formula: C10H15ClN5O13P3 (free acid). Mole weight: 541.6 (free acid). | |
| 2-Cyclopropylcarbonyl-3-dimethylaminoacrylic Acid Methyl Ester | 2-Cyclopropylcarbonyl-3-dimethylaminoacrylic Acid Methyl Ester is an intermediate in the preparation of soluble guanylyl cyclase activators. Group: Biochemicals. Alternative Names: α -[ (Dimethylamino) methylene]- β-oxo-cyclopropanepropanoic Acid Methyl Ester;Methyl 2- (Cyclopropylcarbonyl) -3- (dimethylamino) acrylate; Methyl 2-(Cyclopropylcarbonyl)-3-(dimethylamino)prop-2-enoate. Grades: Highly Purified. CAS No. 340774-26-7. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| 2'-?MeCCPA | 2'-?MeCCPA is an inhibitor of forskolin-stimulated adenylyl cyclase. It is also a selective A1 adenosine receptor agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 205171-12-6. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H22ClN5O4, Molecular Weight: 383.83. US Biological Life Sciences. | Worldwide |
| 2-MeS-5'-AMP | 2-MeS-5'-AMP is a potent antagonist of adenylate cyclase-coupled platelet ADP P2Y purinoceptor. Synonyms: 2- Methylthioadenosine- 5'- O- monophosphate, sodium salt. Grades: ≥ 97% by HPLC. CAS No. 22140-20-1. Molecular formula: C11H16N5O7PS (free acid). Mole weight: 393.3 (free acid). | |
| 2-MeS-ATP | 2-MeS-ATP is an agonist of P2Y purinoceptors that inhibits soluble guanylate cyclase. Uses: Purinergic agonists. Synonyms: 2- Methylthioadenosine- 5'- O- triphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 43170-89-4. Molecular formula: C11H18N5O13P3S (free acid). Mole weight: 553.3 (free acid). | |
| 2-methylisoborneol synthase | The product, 2-methylisoborneol, is a characteristc odiferous compound with a musty smell produced by soil microorganisms. Group: Enzymes. Synonyms: sco7700; 2-MIB cyclase; MIB synthase; MIBS. Enzyme Commission Number: EC 4.2.3.118. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5130; 2-methylisoborneol synthase; EC 4.2.3.118; sco7700; 2-MIB cyclase; MIB synthase; MIBS. Cat No: EXWM-5130. | |
| 2-Palmitoylglycerol | 2-Palmitoylglycerol is an endogenous fatty acid glycerol ester that enhances activity of 2-arachidonylglycerol. It is an endogenous agonist of the CB1 and CB2 cannabinoid receptors. 2-Palmitoylglycerol does not bind directly to cannabinoid receptors, nor inhibit adenylyl cyclase, but rather potentiates the activity of 2-AG (and other endocannabinoids) to bind to CB1 and CB2 and inhibit adenylyl cyclase. Synonyms: 2-Hydroxy-1-(hydroxymethyl)ethyl hexadecanoic acid ester; 2-Monohexadecanoylglycerol; 2-Monopalmitin; 2-Monopalmitoyl-sn-glycerol; 2-Monopalmitoylglycerol; 2-Palmitoylglycerol; Glycerol-β-palmitate; Palmitic Acid β-monoglyceride; β-Monopalmitin. CAS No. 23470-00-0. Molecular formula: C19H38O4. Mole weight: 330.51. | |
| 3,5,7-trioxododecanoyl-CoA synthase | A polyketide synthase catalysing the first committed step in the cannabinoids biosynthetic pathway of the plant Cannabis sativa. The enzyme was previously thought to also function as a cyclase, but the cyclization is now known to be catalysed by EC 4.4.1.26, olivetolic acid cyclase. Group: Enzymes. Synonyms: TKS (ambiguous); olivetol synthase (incorrect). Enzyme Commission Number: EC 2.3.1.206. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2151; 3,5,7-trioxododecanoyl-CoA synthase; EC 2.3.1.206; TKS (ambiguous); olivetol synthase (incorrect). Cat No: EXWM-2151. | |
| 3-Cyano-2-oxo-propionic Acid Ethyl Ester Sodium Salt | 3-Cyano-2-oxo-propionic Acid Ethyl Ester Sodium Salt is used in the preparation of stimulators of soluble guanylate cyclase. Group: Biochemicals. Grades: Highly Purified. CAS No. 53544-13-1. Pack Sizes: 500mg, 1g. Molecular Formula: C6H6NNaO3, Molecular Weight: 163.11. US Biological Life Sciences. | Worldwide |
| 4-(Benzyloxy)benzaldehyde | Ibuprofen Related Compound is a position isomer of the adenylyl cyclase activator 2-Benzyloxybenzaldehyde. It also has much less potent anticancer activity against HL-60 cells that its isomeric counterpart. Synonyms: 4-phenylmethoxybenzaldehyde. Grades: > 95 %. CAS No. 4397-53-9. Molecular formula: C14H12O2. Mole weight: 212.24. | |
| 4-Phenyl-3-furoxancarbonitrile (Furoxan, RVC-589) | Able to activate the soluble guanylate cyclase by releasing Nitric Oxide under the action of thiol cofactors. Also inhibits platelet aggregation. Group: Biochemicals. Alternative Names: Furoxan, RVC-589. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| (4S)-limonene synthase | A recombinant enzyme (also known as a monoterpene synthase or cyclase) from the grand fir (Abies grandis) requires Mn2+ and K+ for activity. Mg2+ is essentially ineffective as the divalent metal ion cofactor. Group: Enzymes. Synonyms: (-)-(4S)-limonene synthase; 4S-(-)-limonene synthase; geranyldiphosphate diphosphate lyase (limonene forming); geranyldiphosphate diphosphate lyase [cyclizing, (4S)-limonene-forming]; geranyl-diphosphate diphosphate-lyase [cyclizing; (-)-(4S)-limonene-forming]. Enzyme Commission Number: EC 4.2.3.16. CAS No. 110639-20-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5172; (4S)-limonene synthase; EC 4.2.3.16; 110639-20-8; (-)-(4S)-limonene synthase; 4S-(-)-limonene synthase; geranyldiphosphate diphosphate lyase (limonene forming); geranyldiphosphate diphosphate lyase [cyclizing, (4S)-limonene-forming]; geranyl-diphosphate diphosphate-lyase [cyclizing; (-)-(4S)-limonene-forming]. Cat No: EXWM-5172. | |
| 4-Thio-i-propyl-UTP | 4-Thio-i-propyl-UTP, a biochemical compound used in biomedical research, is known for its efficacy in the evaluation of P2Y receptor function. Scientists heavily rely on it to look at signaling pathways implicated in diseases affecting multiple organ systems such as cancer, diabetes, and neurodegenerative disorders. This substrate has the power to activate adenylate cyclase through P2Y receptor-mediated processes. Studying these receptors using this compound has been shown to shed light on pathogenic mechanisms. Its use is well-established across the scientific community, both in vitro and in vivo. Synonyms: 4-Thio-iso-propyl-uridine-5'-triphosphate, Sodium salt. Grades: ≥ 95% by HPLC. Molecular formula: C12H21N2O14P3S (free acid). Mole weight: 542.27 (free acid). | |
| 5-epiaristolochene synthase | Initial cyclization gives (+)-germacrene A in an enzyme bound form which is not released to the medium. Group: Enzymes. Synonyms: 5-epi-aristolochene synthase; tobacco epiaristolochene synthase; farnesyl pyrophosphate cyclase (ambiguous); EAS; TEAS. Enzyme Commission Number: EC 4.2.3.61. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5222; 5-epiaristolochene synthase; EC 4.2.3.61; 5-epi-aristolochene synthase; tobacco epiaristolochene synthase; farnesyl pyrophosphate cyclase (ambiguous); EAS; TEAS. Cat No: EXWM-5222. | |
| 5'-hydroxyaverantin dehydrogenase | Isolated from the aflatoxin-producing mold Aspergillus parasiticus. Involved in aflatoxin biosynthesis. 5'-Oxoaverantin will spontaneously form averufin by intramolecular ketalisation. cf. EC 4.2.1.142, 5'-oxoaverantin cyclase. Group: Enzymes. Synonyms: HAVN dehydrogenase; adhA (gene name). Enzyme Commission Number: EC 1.1.1.352. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0268; 5'-hydroxyaverantin dehydrogenase; EC 1.1.1.352; HAVN dehydrogenase; adhA (gene name). Cat No: EXWM-0268. | |
| 5-Nonyloxytryptamine oxalate | 5-Nonyloxytryptamine oxalate is a potent agonist of the serotonin (5-HT) receptor 5-HT1Dβ with an EC50 value of 68 nM for adenylate cyclase activity in CHOKM6 cells transfected with the human 5-HT1Dβ receptor. It is several times more potent than sumatriptan and inactive as a 5-HT1A agonist (Ki at 5-HT1B = 1 nM, selectivity over 5-HT1A > 300-fold). Synonyms: 5-(Nonyloxy)-1H-Indole-3-ethanamine ethanedioate; 5-(Nonyloxy)tryptamine oxalate; 5-Nonyloxytryptamine oxalate. Grades: ≥99% by HPLC. CAS No. 157798-13-5. Molecular formula: C19H30N2O.C2H2O4. Mole weight: 392.49. | |
| 6-Anilino-5,8-quinolinedione (LY 83583) | Inhibits nitric-oxide-induced activation of soluble guanylate cyclase (IC50=2µM) in a dose-dependent and reversible manner. It blocks acetylcholine induced vasorelaxation. Also an inhibitor of antigen-induced leukotriene release. Group: Biochemicals. Alternative Names: LY 83583. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 6-Chloro-5-(2,3-dichlorophenoxy)-2-methylthio-benzimidazole (Triclabendazole) | Triclabendazole is a member of the benzimidazole family of anthelmintics. It is effective against F. hepatica helminths that cause fascioliasis, reducing secreted protease enzyme activities that are critical for the invasion, migration, nutrition, and survival of the parasite.1 In yeast and mammalian cells, triclabendazole was shown to inhibit adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A nutrient-sensing pathway and to prevent apoptosis induced by the Parkinsons disease-related protein α-synuclein, demonstrating a protective role during various cellular stresses.2,3. Group: Biochemicals. Alternative Names: 5-Chloro-6- (2, 3-dichlorophenoxy) -2- methyl thiobenzimidazole; CGA-89317, egaten; Fasinex; Triclabendazole. Grades: Highly Purified. CAS No. 68786-66-3. Pack Sizes: 25g, 50g, 100g. Molecular Formula: C14H9Cl3N2OS, Molecular Weight: 359.66. US Biological Life Sciences. | Worldwide |
| 6-Chloropurine Riboside 5'-Triphosphate Triethylamine Salt | 6-Chloropurine Riboside 5'-Triphosphate Triethylamine Salt is a structural analog of Adenosine Triphosphate (ATP) and can irreversibly inhibit adenylate cyclase from rat brains. Synonyms: 6-Chloro-9-[5-O-[hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-9H-purine Triethylamine Salt. Molecular formula: C10H14ClN4O13P3(free acid). Mole weight: 526.61. | |
| 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - Cy3 | 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - Cy3 is a fluorescently labeled nucleotide analog that is utilized for the purpose of monitoring adenylate cyclase activity and intracellular signaling pathways. This unique compound boasts a wide range of applications, such as studying the activation of the Gs protein-coupled receptor, which then activates its downstream effectors PKA and CREB. Not only is this product useful in understanding these critical signaling pathways, but also in drug development procedures that aim to target GPCR signaling pathways. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate, labeled with Cy3, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C47H65N9O17P2S2 (free acid). Mole weight: 1154.15 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate - DY-480XL | DY-480XL, a biomedicine product specialized in biochemical studies, offers an intricate solution to understanding the dynamics of enzymatic interactions and signaling pathways. As a fluorescent analog of 2',5'-ADP, this product boasts the capability to study complex enzyme activities such as adenylate cyclase and cyclic nucleotide phosphodiesterase. Furthermore, it can delve into the intricate signaling pathways activated by extracellular receptors, which induce G protein-coupled pathways. The product's versatility renders it invaluable in the oncology research sphere, with its potential applications ranging from breast, ovarian to colon cancer. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-2',5'-bisphosphate, labeled with DY 480XL, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C42H57N9O16P2S (free acid). Mole weight: 1037.97 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate - 6-FAM | 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate - 6-FAM is a fluorescently-labeled derivative of adenosine-3',5'-bisphosphate, a signaling molecule and second messenger within cells. This product is used in biomedical research to study the regulation of intracellular signaling pathways involving adenylate cyclase and phosphodiesterases. It can also be used to investigate nucleotide metabolism and the role of adenylyl cyclases in diseases such as cardiac and neurological disorders. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-bisphosphate, labeled with 6 FAM, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H39N7O16P2 (free acid). Mole weight: 899.70 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - 6-JOE | 8-[(6-Amino)hexyl]-amino-cAMP - 6-JOE, a fluorescent analog of cyclic AMP, presents immense academic value as a research tool for investigating cellular signaling pathways through adenylyl cyclase and phosphodiesterase activity, as well as cAMP receptor binding. Its diverse potential applications to the regulation of cellular signaling in diseases such as diabetes and heart disease, underscores its profound scientific relevance. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with 6-JOE, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C39H38Cl2N7O14P (free acid). Mole weight: 929.16 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-495 | 8-[(6-Amino)hexyl]-amino-cAMP - ATTO-495, a fluorescent probe with highly-specific binding properties to the regulatory subunit of PKA, is a powerful tool that can monitor the activity of adenylate cyclase in living cells. Its utility extends beyond just studying PKA activity, as it can also aid in the identification of targets for cancer treatment by investigating the role of cAMP in cancer cells. With its vast array of research applications, this product is a must-have for any serious researcher. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with ATTO 495, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C37H49N10O7P (free acid). Mole weight: 776.82 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cAMP - DY-751 | 8-[(6-Amino)hexyl]-amino-cAMP - DY-751 is an intricate and sophisticated synthetic compound, serving as an exceptional and exclusive cyclic adenosine monophosphate (cAMP) analogue that possesses a structurally modified framework. Demonstrating remarkable potency, DY-751 acting as an efficacious agonist, displaying selectivity towards specific subcategories of adenylyl cyclase. Synonyms: 8-[(6-Amino)hexyl]-amino-adenosine-3',5'-cyclic monophosphate, labeled with DY 751, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C58H76N9O14PS2 (free acid). Mole weight: 1217.47 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-390 | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-390, a luminescent marker, offers researchers a viable tool to evaluate cyclic nucleotide signaling pathways. It furnishes a mechanism to assay guanylyl cyclase action, as well as drug responsiveness. Moreover, its application has the potential for wider clinical utilization including drug delivery and cancer diagnosis. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 390, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C36H49N8O10P (free acid). Mole weight: 784.80 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-612Q | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-612Q, a fluorescent probe, designed to assist biomedical research in investigating guanylyl cyclase enzyme activity and cGMP-related signaling pathways, as well as studying the pathogenesis of cardiovascular diseases and cancer. The intricacies of this product are profound whilst remaining highly practical, offering a truly unique insight into its potential. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 612Q, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H24N7O7P - ATTO 612Q (free acid). Mole weight: 1131.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-647N | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-647N is a fluorescent probe used for imaging guanylyl cyclase and monitoring cGMP signaling pathways in biological systems. This product can also be utilized in the diagnosis and treatment of disorders related to the activation or inhibition of guanylyl cyclase and cGMP. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 647N, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 647N (free acid). Mole weight: 1086.39 (free acid). | |
| 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-740 | 8-[(6-Amino)hexyl]-amino-cGMP - ATTO-740, a fluorescent probe, is a valuable tool in biomedical research for investigating the function of guanylyl cyclases and soluble guanylate cyclases. Notably, this versatile probe can be used to study the mechanisms underlying cardiovascular diseases and neuronal disorders, thereby offering the potential for significant scientific breakthroughs and medical advancements. Its reliability and efficacy make it a highly sought-after compound for researchers across diverse fields. Synonyms: 8-[(6-Amino)hexyl]-amino-guanosine-3',5'-cyclic monophosphate, labeled with ATTO 740, Triethylammonium salt. Grades: ≥ 95% by HPLC. Molecular formula: C16H26N7O7P - ATTO 740 (free acid). Mole weight: 908.39 (free acid). | |
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