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Cadaverine is a polyamine produced by the decarboxylation of L-lysine, and is also produced by E. coli cells when grown in acidic pH. Cadaverine is known to inhibit porin-mediated outer membrane permeability in E. coli.Cadaverine is a diamine that can be used in hetarylation with halopyridines (2-bromo, 2-iodo, and 3-iodo-pyridines) to synthesize N,N?-dipyridinyl diamine derivatives in the presence of CuI-2-isobutyryl cyclohexanone as a catalyst. It can also be used to synthesize a poly-imidazolium polymer with high thermal stability by reacting with acetic acid, pyruvaldehyde and formaldehyde by modified Debus-Radziszewski reaction. Group: Biochemicals. Alternative Names: 1,5-Pentanediamine; Cadavarine. Grades: Highly Purified. CAS No. 462-94-2. Pack Sizes: 5g, 25g. Molecular Formula: C5H14N2, Molecular Weight: 102.18. US Biological Life Sciences.
Worldwide
(Acetylacetonato)(1,5-cyclooctadiene)iridium(I)
(Acetylacetonato)(1,5-cyclooctadiene)iridium(I). Uses: Convenient precursor to a variety of iridium complexes and catalysts. Group: Metal gauzessolution deposition precursors. Alternative Names: 1, 5-CYCLOOCTADIENE (ACETYLACETONATO)IRIDIUM (I); (ACETYLACETONATO)(1,5-CYCLOOCTADIENE)IRIDIUM(I); IRIDIUM I PENTANEDIONATE-CYCLO-OCTADIENE COMPLEX; ((1,2,5,6-eta)-1,5-cyclooctadiene)(2,4-pentanedionato-o,o')-iridiu; (1,5-cyclooctadiene)(2,4-pentanedionato)irid. CAS No. 12154-84-6. Product ID: cyclooctane; (Z)-4-hydroxypent-3-en-2-one; iridium. Molecular formula: 399.51. Mole weight: C13H19IrO2. C[C-]=CC(=O)C. C1C[CH][CH]CC[CH][CH]1. [Ir]. RBTXDZDKTGRPBP-LWFKIUJUSA-N. 0.98.
(Acetylacetonato)(1,5-cyclooctadiene)iridium(I)
Convenient precursor to a variety of Iridium complexes and catalysts. Group: Micro/nanoelectronics. Alternative Names: 1, 5-CYCLOOCTADIENE (ACETYLACETONATO)IRIDIUM (I);(ACETYLACETONATO)(1,5-CYCLOOCTADIENE)IRIDIUM(I);IRIDIUM I PENTANEDIONATE-CYCLO-OCTADIENE COMPLEX;((1,2,5,6-eta)-1,5-cyclooctadiene)(2,4-pentanedionato-o,o')-iridiu;(1,5-cyclooctadiene)(2,4-pentanedionato)irid. CAS No. 12154-84-6. Molecular formula: C13H19IrO2. Mole weight: 399.51. Appearance: yellow powder. Purity: 0.98. IUPACName: cyclooctane; (Z)-4-hydroxypent-3-en-2-one; iridium. Canonical SMILES: C[C-]=CC(=O)C. C1C[CH][CH]CC[CH][CH]1. [Ir]. Catalog: ACM12154846.
Acetylacetonatobis (cyclooctene)rhodium (I), min. 97%
Rhodium source used in combination with phosphine ligands to catalyze the 1,4-addition of arylboronic acids to α,β-unsaturated carbonyl compounds. Rhodium source for the catalytic addition of arylboronic acids to N-tert-butanesulfinyl imino esters. Group: Rhodium series of catalysts. Alternative Names: ACETYLACETONATOBIS (CYCLOOCTENE)RHODIUM (I); 34767-55-0; MFCD06658137; SC10118; ACETYLACETONATOBIS (CYCLOOCTENE)RHODIUM (I);BIS(CYCLOOCTENE)(2,4-PENTANEDIONATO)RHODIUM. CAS No. 34767-55-0. Molecular formula: C21H36O2Rh. Mole weight: 423.422g/mol. IUPACName: cyclooctane;(Z)-4-hydroxypent-3-en-2-one;rhodium. Canonical SMILES: CC(=CC(=O)C)O. C1CCC[CH][CH]CC1. C1CCC[CH][CH]CC1. [Rh]. Catalog: ACM34767550.
BGC-945
BGC 945 is a cyclopenta[g]quinazoline-based, thymidylate synthase inhibitor specifically transported into α-folate receptor (α-FR)-overexpressing tumors. BGC 945 has low affinity for the widely expressed reduced-folate carrier (RFC). BGC 945 selectively inhibits thymidylate synthase in α-FR-overexpressing tumors and should cause minimal toxicity to humans at therapeutic doses. Synonyms: Idetrexed; ONX-0801; N-[4-[2-Propynyl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-1H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; N-[4-[2-Propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-L-γ-glutamyl-D-glutamic acid; (R) -2- ( (S) -4-carboxy-4- (4- ( ( (S) -2- (hydroxymethyl) -4-oxo-4, 6, 7, 8-tetrahydro-3H-cyclopenta[g]quinazolin-6-yl) (prop-2-yn-1-yl) amino) benzamido) butanamido) pentanedioic acid. Grades: ≥95%. CAS No. 501332-69-0. Molecular formula: C32H33N5O10. Mole weight: 647.63.
Irbesartan impurity
An impurity of Irbesartan. Synonyms: N-((2'-cyanobiphenyl-4-yl)methyl)-1-pentanamido cyclopentane carboxamide. Grades: > 95%. CAS No. 141745-71-3. Molecular formula: C25H29N3O2. Mole weight: 403.53.
Irbesartan Related Compound A
A metabolite of Irbesartan, an angiotensin II receptor blocker used for the treatment of high blood pressure, heart failure, and diabetic kidney disease. Synonyms: 1-pentanoylamino-cyclopentanecarboxylic acid [2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amide. Grades: > 95%. CAS No. 748812-53-5. Molecular formula: C25H30N6O2. Mole weight: 446.56.
KB-0742 HCl
KB-0742 is an orally bioavailable, selective CDK9 inhibitor with potent anti-tumor activity in CRPC models. In 22Rv1 cells, KB-0742 rapidly downregulates nascent transcription, preferentially depleting short half-life transcripts and AR-driven oncogenic programs. In vivo, oral administration of KB-0742 significantly reduced tumor growth in CRPC, supporting CDK9 inhibition as a promising therapeutic strategy to target AR dependence in CRPC. Group: Inhibitors. Alternative Names: KB-0742; KB0742; KB 0742 2HCl; KB 0742 dihydrochloride; KB 0742 hydrochloride. CAS No. 2416874-75-2. Molecular formula: C16H27Cl2N5. Mole weight: 360.33. Appearance: Solid powder. Purity: >98%. IUPACName: (1S,3S)-N1-(5-(pentan-3-yl)pyrazolo[1,5-a]pyrimidin-7-yl)cyclopentane-1,3-diamine dihydrochloride. Canonical SMILES: CCC (CC)C1=NC2=CC=NN2C (N[C@@H]3C[C@@H] (N)CC3)=C1. Cl. Cl. Catalog: ACM2416874752.
15-cyclohexyl pentanor PGF2α is an analog of PGF2α with resistance to 15-hydroxy PGDH metabolism. Synonyms: 15-cyclohexyl pentanor PGF2α; (Z)-7-[(1R,2R,3R,5S)-2-[(E,3S)-3-cyclohexyl-3-hydroxyprop-1-enyl]-3,5-dihydroxycyclopentyl]hept-5-enoic acid. Grades: ≥96%. CAS No. 58611-97-5. Molecular formula: C21H34O5. Mole weight: 366.5.
16(R)-AFP 07
16(R)-AFP 07 is an epimer of AFP 07, a selective and highly potent agonist for the IP receptor (Ki = 0.561 nM). Synonyms: (5E)-5-[(3aR,4R,5R,6aS)-3,3-difluoro-5-hydroxy-4-[(E,3S,4R)-3-hydroxy-4-methylnon-1-en-6-ynyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[b]furan-2-ylidene]pentanoic acid. Grades: ≥98%. CAS No. 773825-80-2. Molecular formula: C22H30F2O5. Mole weight: 412.5.
(1R,5S,6R)-ethyl 5-(pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate is an impurity of Oseltamivir, which is an acetamido cyclohexene that is a structural homolog of sialic acid and inhibits neuraminidase. Synonyms: (1R,5S,6R)-5-(1-Ethylpropoxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylic Acid Ethyl Ester. CAS No. 2413185-89-2. Molecular formula: C14H22O4. Mole weight: 254.32.
(1R,5S,6R)-Ethyl 5-(Pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate is the enantiomer of Ethyl (3R,4S,5S)-4,5-Epoxy-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylate (E917820), an intermediate of Oseltamivir. Group: Biochemicals. Grades: Highly Purified. CAS No. 347378-74-9. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C14H22O4. US Biological Life Sciences.
(1R,5S,6R)-Ethyl 5-(Pentan-3-yloxy-d5)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate is the labeled analogue of (1R,5S,6R)-Ethyl 5-(Pentan-3-yloxy)-7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate (E917990), the enantiomer of Ethyl (3R,4S,5S)-4,5-Epoxy-3-(1-ethylpropoxy)cyclohex-1-ene-1-carboxylate (E917820), an intermediate of Oseltamivir. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C14H17D5O4, Molecular Weight: 259.35. US Biological Life Sciences.
2-Debenzoyl Paclitaxel 2-Pentanoate is an impurity of Paclitaxel, which is a mitotic inhibitor used in cancer chemotherapy. Synonyms: Benzenepropanoic acid, β-(benzoylamino)-α-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-12-[(1-oxopentyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (αR,βS)-; (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-12-[(1-oxopentyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl (αR,βS)-β-(benzoylamino)-α-hydroxybenzenepropanoate; (αR,βS)-β-(Benzoylamino)-α-hydroxy-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-12-[(1-oxopentyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester. Grades: ≥95%. CAS No. 213767-22-7. Molecular formula: C45H55NO14. Mole weight: 833.94.
(4R,5S)-Methyl 4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate is an impurity of Oseltamivir, which can be used in COVID19-related research. Synonyms: ZINC 036451498. Molecular formula: C15H26N2O4. Mole weight: 298.38.
(3R,4S,5R)-Ethyl 5-Acetoxy-3-hydroxy-4-(pentan-3-yloxy)cyclohex-1-enecarboxylate is an intermediate in the synthesis of Oseltamivir, which is an antiviral drug used to treat and prevent influenza A and B viruses. Synonyms: ethyl (3R,4S,5R)-5-acetoxy-3-hydroxy-4-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate; Ethyl (3R,4S,5R)-5-acetoxy-3-hydroxy-4-(3-pentanyloxy)-1-cyclohexene-1-carboxylate; 1-Cyclohexene-1-carboxylic acid, 5-(acetyloxy)-4-(1-ethylpropoxy)-3-hydroxy-, ethyl ester, (3R,4S,5R)-. Molecular formula: C16H26O6. Mole weight: 314.37.
(3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt
(3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-7,8-dihydro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid Sodium Salt. Molecular formula: C25H23FNNaO4. Mole weight: 443.44.
(3R)-Ethyl 5-azido-4-((methylsulfonyl)oxy)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate is an intermediate in the synthesis of Oseltamivir, which is an antiviral drug used to treat and prevent influenza A and B viruses. Synonyms: Ethyl (3R)-5-azido-4-[(methylsulfonyl)oxy]-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate; 1-Cyclohexene-1-carboxylic acid, 5-azido-3-(1-ethylpropoxy)-4-[(methylsulfonyl)oxy]-, ethyl ester, (3R)-. CAS No. 1216260-26-2. Molecular formula: C15H25N3O6S. Mole weight: 375.44.
(3S,4S,5R)-Ethyl 5-Acetoxy-4-hydroxy-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate is an intermediate in the synthesis of Oseltamivir, which is an antiviral drug used to treat and prevent influenza A and B viruses. Synonyms: Ethyl (3S,4S,5R)-5-acetoxy-4-hydroxy-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate; 1-Cyclohexene-1-carboxylic acid, 5-(acetyloxy)-3-(1-ethylpropoxy)-4-hydroxy-, ethyl ester, (3S,4S,5R)-. CAS No. 347378-70-5. Molecular formula: C16H26O6. Mole weight: 314.37.
(3S,4S,5R)-Ethyl 5-Acetoxy-4-((methylsulfonyl)oxy)-3-(pentan-3-yloxy)cyclohex-1-enecarboxylate is an intermediate of enantiomeric derivatives of Oseltamivir, which can be used in COVID19-related research. Synonyms: Ethyl (3S,4S,5R)-5-acetoxy-4-[(methylsulfonyl)oxy]-3-(3-pentanyloxy)-1-cyclohexene-1-carboxylate; 1-Cyclohexene-1-carboxylic acid, 5-(acetyloxy)-3-(1-ethylpropoxy)-4-[(methylsulfonyl)oxy]-, ethyl ester, (3S,4S,5R)-. CAS No. 347378-72-7. Molecular formula: C17H28O8S. Mole weight: 392.46.
4-[2-(3-Benzyloxycarbonylamino-4-cyclohexyl-1-hydroxy-2-OXO-butylamino)-5-guanidino-pentanoylamino]-4-(1-carboxy-2-cyclohexyl-ethylcarbamoyl)-butyric acid is a formidable biomedical compound exhibiting remarkable potential in studying specific malignancies. Through the inhibition of cancer cell growth and the promotion of apoptosis, it has displayed efficacious results in studying breast, lung and colon cancer. Synonyms: (4S) -5-[[ (1S) -1-carboxy-2-cyclohexylethyl]amino]-4-[[ (2S) -2-[[ (3R) -4-cyclohexyl-2-oxo-3- (phenylmethoxycarbonylamino) butanoyl]amino]-5- (diaminomethylideneamino) pentanoyl]amino]-5-oxopentanoic acid. Molecular formula: C38H57N7O10. Mole weight: 771.9.
7-O-(Triethylsilyl)-2'-O-tert-butyl(dimethyl)silyl 2-Debenzoyl Paclitaxel 2-Pentanoate is a derivative of Paclitaxel, which is a chemotherapy medication used to treat a number of types of cancer. Synonyms: (αR,βS)-β-(Benzoylamino)-α-tert-butyl(dimethyl)silyloxy-benzenepropanoic Acid (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-Bis(acetyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4-triethylsilyloxy-11-hydroxy-4a,8,13,13-tetramethyl-5-oxo-12-[(1-oxopentyl)oxy]-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester; (2α, 5β, 7β, 10β, 13α)-4, 10-Diacetoxy-13-{[(2R, 3S)-3-(benzoylamino)-2-{[dimethyl(2-methyl-2-propanyl)silyl]oxy}-3-phenylpropanoyl]oxy}-1-hydroxy-9-oxo-7-[(triethylsilyl)oxy]-5, 20-epoxytax-11-en-2-yl valerate. Grades: 98%. CAS No. 1055033-93-6. Molecular formula: C57H83NO14Si2. Mole weight: 1062.43.
AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor. Synonyms: (5Z)-5-[(3aR,4R,5R,6aS)-3,3-difluoro-5-hydroxy-4-[(E,3S,4S)-3-hydroxy-4-methylnon-1-en-6-ynyl]-4,5,6,6a-tetrahydro-3aH-cyclopenta[b]furan-2-ylidene]pentanoic acid. Grades: ≥98%. CAS No. 788799-13-3. Molecular formula: C22H30F2O5. Mole weight: 412.5.
Alloisolithocholic acid
Alloisolithocholic acid is a steroid compound used for treatment of inflammatory or autoimmune disorders. Synonyms: 5α-cholanic acid-3β-ol; (3β,5α)-3-Hydroxycholan-24-oic Acid; 3β-Hydroxy-5α-cholanic Acid; 3beta-Hydroxy-5alpha-cholan-24-oic Acid; NSC 18169; (R)-4-((3S,5S,8R,9S,10S,13R,14S,17R)-3-Hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic Acid; Isoallolithocholic acid. Grades: >99%. CAS No. 2276-93-9. Molecular formula: C24H40O3. Mole weight: 376.57.
Betamethasone Acetate EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate. CAS No. 33755-46-3. Molecular Formula: C27H37FO6. Mole Weight: 476.58. Catalog: APB33755463.
Betamethasone valerate EP Impurity C
Betamethasone valerate EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Betamethasone valerate EP Impurity C; (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate. Molecular Formula: C27H37FO6. Mole Weight: 476.58. Catalog: APB03706.
Betamethasone valerate EP Impurity D
Betamethasone valerate EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8S,9R,10S,11S,13S,14S,16S,17R)-9-bromo-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate. Molecular Formula: C27H37BrO6. Mole Weight: 537.48. Catalog: APB03703.
Betamethasone valerate EP Impurity E
Betamethasone valerate EP Impurity E. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2-((8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl pentanoate. Molecular Formula: C27H37FO6. Mole Weight: 476.58. Catalog: APB03704.
Betamethasone valerate EP Impurity F
Betamethasone valerate EP Impurity F. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8S,10S,13S,14S,16S,17R)-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,10,12,13,14,15,16,17-decahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate. Molecular Formula: C27H36O5. Mole Weight: 440.57. Catalog: APB03700.
Betamethasone valerate EP Impurity G
Betamethasone valerate EP Impurity G. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (6S,8S,9R,10S,11S,13S,14S,16S,17R)-6-bromo-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate. Molecular Formula: C27H36BrFO6. Mole Weight: 555.47. Catalog: APB03702.
Betamethasone valerate EP Impurity H
Betamethasone valerate EP Impurity H. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate. Molecular Formula: C27H37ClO6. Mole Weight: 493.03. Catalog: APB03701.
Betamethasone valerate EP Impurity I
Betamethasone valerate EP Impurity I. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Betamethasone valerate EP Impurity I; (8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl pentanoate. Molecular Formula: C27H37FO6. Mole Weight: 476.58. Catalog: APB03699.
BIIE 0246
BIIE 0246 is a potent, selective and non-peptide antagonist which binds to the neuropeptide Y Y2 receptor (IC50 = 15 nM) with > 650-fold selectivity over Y1, Y4 and Y5 receptors. Synonyms: (2S) -5- (diaminomethylideneamino) -N- [2- (3, 5-dioxo-1, 2-diphenyl-1, 2, 4-triazolidin-4-yl) ethyl] -2- [ [2- [1- [2-oxo-2- [4- (6-oxo-5, 11-dihydrobenzo [c] [1] benzazepin-11-yl) piperazin-1-yl] ethyl] cyclopentyl] acetyl] amino] pentanamide; BIIE-0246; BIIE 0246; BIIE-0246; CHEMBL540989; GTPL1547; CTK8E9439; BIIE0246. Grades: >98 %. CAS No. 246146-55-4. Molecular formula: C49H57N11O6. Mole weight: 896.05.
Biotin-Azide(≥97% )
Biotin azide reacts with the terminal alkynes via a copper-catalyzed click reaction, including biomolecules containing alkyne groups through azide-alkyne cycloaddition. Biotin and biotin derivatives can be readily conjugated to various biomolecules through the well-known click chemistry and subsequently detected with streptavidin, avidin or NeutrAvidin biotin-binding protein. Biotin azide can be used to prepare various biotinylated conjugates via Click Chemistry. Click chemistry contains a class of chemical reactions that use bio-orthogonal or biologically unique moieties to label and detect the molecule in mild and aqueous conditions. This reagent allows labeling of various alkynylated molecules, such as DNA, oligonucleotides, and proteins with biotin. Biotin binding to avidin or streptavidin could be used in downstream affinity applications for the isolation of biotinylated molecules or their binding with streptavidin conjugates [1]. Uses: Useful for biotinylation of reagents. Group: Biotinylation reagents. Alternative Names: Biotin-Azide. CAS No. 1006592-62-6. Molecular formula: C27H49N7O7S. Mole weight: 615.79 g/mol. Appearance: To be determined. Purity: ≥97%. IUPACName: N-(6-azidohexyl)-1-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)-3,6,9,12-tetraoxapentadecan-15-amide. Canonical SMILES: [H][C@@]1 (N2)[C@] ([C@H] (CCCCC (NCCOCCOCCOCCOCCC (NCCCCCCN=[N+]=[N-])=O)=O)SC1) ([H])NC2=
CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 μM, respectively). CAP 3 increases the fluidity of model Gram-negative bacterial membranes and binds to LPS in vitro. It reduces the biomass and number of colony-forming units in E. coli biofilms in a concentration-dependent manner. CAP 3 inhibits E. coli biofilm formation on catheters implanted in mice infected with E. coli at the incision site when applied as a coating on the catheters. CAP 3 (40 mg/kg) also reduces bacterial load in E. coli-infected wounds in mice. It is cytotoxic to A459 cells (IC50 = 56.4 μM) and has hemolytic activity against human red blood cells with a 50% lysis (HC50) value of 48 μM. Synonyms: CAP 3; CHEMBL5173640; benzyl (4R)-4-[(3R, 5S, 7R, 8R, 9S, 10S, 12S, 13R, 14S, 17R)-3, 7, 12-tris[[2-[(2-amino-3-methylbutanoyl)amino]acetyl]oxy]-10, 13-dimethyl-2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 14, 15, 16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoate. Grades: ≥98%. Molecular formula: C52H82N6O11. Mole weight: 967.3.
Carfilzomib Impurity 45
Carfilzomib Impurity 45. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-2-((S)-4-cyclohexyl-2-(2-morpholinoacetamido)butanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide. Molecular Formula: C40H63N5O7. Mole Weight: 725.96. Catalog: APB04730.
Deoxycholic acid (DCA) is a bile acid that plays an important role in the digestion and absorption of dietary fats and fat-soluble vitamins. Uses: It is a natural component of the human body and is produced in the liver from cholesterol. it is also used in laboratory experiments to study the effects of bile acids on cell physiology, metabolism, and gene expression. Group: Heterocyclic organic compound. Alternative Names: Choleic acid. CAS No. 83-44-3. Molecular formula: C24H40O4. Mole weight: 392.58. Appearance: White to off-white solid. Purity: 0.98. IUPACName: (4R)-4-[(3R, 5R, 8R, 9S, 10S, 12S, 13R, 14S, 17R)-3, 12-Dihydroxy-10, 13-dimethyl-2, 3, 4, 5, 6, 7, 8, 9, 11, 12, 14, 15, 16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid. Canonical SMILES: CC (CCC (=O)O)C1CCC2C1 (C (CC3C2CCC4C3 (CCC (C4)O)C)O)C. Density: 1.1±0.1 g/mL. ECNumber: 201-478-5. Catalog: ACM83443-1.
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