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2,5-Dibromo-3-cyclohexylthiophene is a reagent in the synthesis of new donor/acceptor thiophene coploymer. Group: Biochemicals. Grades: Highly Purified. CAS No. 302912-44-3. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H12Br2S, Molecular Weight: 324.08. US Biological Life Sciences.
Worldwide
SAG Analog (cis-isomer) (Compound 10b, 3, 4-Dichloro-N- (cis-4- (methylamino) cyclohexyl) -N- (3-pyridin-4-ylbenzyl) benzo[b]thiophene-2-carboxamide)
A cell-permeable, highly active, Sonic hedgehog (Shh) signaling agonist. Smoothened (Smo) agonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 1mg. US Biological Life Sciences.
Worldwide
SAG Analog (highly active) (Compound 10b, 3, 4-Dichloro-N- (cis-4- (methylamino) cyclohexyl) -N- (3-pyridin-4-ylbenzyl) benzo[b]thiophene-2-carboxamide)
Cell permeable highly active Sonic hedgehog (Shh) agonist. Group: Biochemicals. Alternative Names: Compound 10b, 3, 4-Dichloro-N- (cis-4- (methylamino) cyclohexyl) -N- (3-pyridin-4-ylbenzyl) benzo[b]thiophene-2-carboxamide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
SAG Analog (trans-isomer) (Compound 10c, 3, 4-Dichloro-N- (trans-4- (methylamino) cyclohexyl) -N- (3-pyridin-4-ylbenzyl) benzo[b]thiophene-2-carboxamide)
A cell-permeable, low toxicity, Sonic hedgehog (Shh) signaling agonist. Smoothened (Smo) agonist. Also acts as a potent activator of VEGF expression in vitro. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug , 1mg. US Biological Life Sciences.
Worldwide
PD-117302
PD-117302, a new nonpeptide opioid compound, is a selective kappa-opioid agonist. It has been evaluated in vivo for antinociceptive activity and other effects characteristic of kappa-receptor activation. It also causes naloxone-reversible locomotor impairment and diuresis. It is used as an Anticonvulsants, an Anti-Arrhythmia agent, a Central Nervous System agent and a Cardiovascular agent. Uses: Pd-117302 is used as an anticonvulsants, an anti-arrhythmia agent, a central nervous system agent and a cardiovascular agent. Synonyms: PD117302; PD-117302; PD 117302; Trans-N-Methyl-N-(2-(1-pyrrolidinyl)cyclohexyl-)benzo-(b)-thiophene-4-acetamide;Benzo(b)thiophene-4-acetamide, N-methyl-N-(2-(1-pyrrolidinyl)cyclohexyl)-, trans-(+-)-;2-(1-Benzothiophen-4-yl)-N-methyl-N-[(1R,2R)-2-pyrrolidin-1-ylcyclohexyl]acetamide;PD117302. Grades: >98%. CAS No. 111728-01-9. Molecular formula: C21H28N2OS. Mole weight: 356.52.
Radalbuvir
Radalbuvir is a Hepatitis C virus NS 5 protein inhibitor for the treatment of hepatitis C virus (HCV) infection developed by Gilead Sciences. In 2014, Gilead completed a phase II trial for Hepatitis C in USA. Uses: Hepatitis c. Synonyms: GS-9669; GS 9669; GS9669; Radalbuvir;5-(3,3-dimethyl-1-butyn-1-yl)-3-((cis-4-hydroxy-4-((((3S)-tetrahydro-3-furanyl)oxy)methyl)cyclohexyl)(((1R)-4-methyl-3-cyclohexen-1-yl)carbonyl)amino)- 2-Thiophenecarboxylic acid. Grades: 98%. CAS No. 1314795-11-3. Molecular formula: C30H41NO6S. Mole weight: 543.72.
SAG 21k
SAG 21k is a potent, brain penetrating and orally available activator of Hedgehog signaling (EC50 = 0.4 nM). Synonyms: 3-Chloro-4, 7-difluoro-N-[[2-methoxy-5- (4-pyridinyl) phenyl]methyl]-N-trans-4- (methylamino) cyclohexyl]benzo[b]thiophene-2-carboxamide. Grades: ≥98% by HPLC. CAS No. 946002-48-8. Molecular formula: C29H28ClF2N3O2S. Mole weight: 556.07.
SAG dihydrochloride
SAG is a potent and cell-permeable Smoothened (Smo) receptor agonist that regulates hedgehog signaling. SAG inhibits hedgehog signaling at high concentrations. Synonyms: 3-Chloro-N-[trans-4- (methylamino) cyclohexyl]-N-[[3- (4-pyridinyl) phenyl]methyl]benzo[b]thiophene-2-carboxamide dihydrochloride. Grades: ≥99% by HPLC. Molecular formula: C28H28ClN3OS.2HCl. Mole weight: 562.98.
2-(4-Fluorophenyl)propan-2-amine Hydrochloride
2-(4-Fluorophenyl)propan-2-amine Hydrochloride acts as a reagent in the discovery of a selective TRPM8 antagonist with clinical efficacy in cold-related pain. Preparation and SAR of piperazinyl -amino-thiophenyl cyclohexyl methanone derivatives as antagonists of the G protein-coupled receptor NPBWR1. Group: Biochemicals. Grades: Highly Purified. CAS No. 1216563-60-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H12FN; HCl, Molecular Weight: 153.203645999999. US Biological Life Sciences.
Worldwide
Avatrombopag Impurity 71
Avatrombopag Impurity 71. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-(4-(4-cyclohexylpiperazin-1-yl)thiophen-2-yl)thiazol-2-amine. Molecular Formula: C17H24N4S2. Mole Weight: 348.53. Catalog: APB02905.
Avatrombopag Impurity 73
Avatrombopag Impurity 73. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 1-(5-(2-amino-5-(4-cyclohexylpiperazin-1-yl)thiazol-4-yl)thiophen-3-yl)piperidine-4-carboxylate. Molecular Formula: C25H37N5O2S2. Mole Weight: 503.72. Catalog: APB03315.
Avatrombopag Impurity 80
Avatrombopag Impurity 80. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(3-chloro-5-((5-(4-cyclohexylpiperazin-1-yl)-4-(thiophen-2-yl)thiazol-2-yl)carbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid. Molecular Formula: C29H35ClN6O3S2. Mole Weight: 615.21. Catalog: APB03314.
Avatrombopag Impurity 94
Avatrombopag Impurity 94. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(4-cyclohexylpiperazin-1-yl)-4-(thiophen-2-yl)thiazol-2-amine. Molecular Formula: C17H24N4S2. Mole Weight: 348.53. Catalog: APB03309.
Boc-β-(3-thienyl)-L-alanine dicyclohexylammonium salt