Cyclooxygenase Suppliers USA
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Product | Description | |
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COX 2 Downstream Primer, 724bp amplimer (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2) Quick inquiry Where to buy Suppliers range | COX 2 Downstream Primer, 724bp amplimer (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2). Group: Molecular Biology. Pack Sizes: 50uM. US Biological Life Sciences. | Worldwide |
COX 2 Upstream Primer, 724bp amplimer (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2) Quick inquiry Where to buy Suppliers range | COX 2 Upstream Primer, 724bp amplimer (Cyclooxygenase 2, PGHS 2, Prostaglandin Endoperoxide Synthase 2, PHS 2). Group: Molecular Biology. Pack Sizes: 50uM. US Biological Life Sciences. | Worldwide |
1,1-Bis(p-isobutylphenyl)ethane Quick inquiry Where to buy Suppliers range | 1,1-Bis(p-isobutylphenyl)ethane (Ibuprofen EP Impurity R) is an impurity in the synthesis of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 102120-87-6. Pack Sizes: 100mg, 1g. Molecular Formula: C22H30. US Biological Life Sciences. | Worldwide |
1,2,4-Triazol-4-amine Quick inquiry Where to buy Suppliers range | 1,2,4-Triazol-4-amine is an intermediate used to prepare potent, selective, and orally active cyclooxygenase-?2 inhibitors. It is also used to synthesize hydroxyphenacyl azoles and related azolium derivatives as antifungal agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 584-13-4. Pack Sizes: 1g, 10 g. Molecular Formula: C2H4N4. US Biological Life Sciences. | Worldwide |
1-(2,6-Dichloro-4-hydroxphenyl)-1,3-dihydroindol-2-one-13C6 Quick inquiry Where to buy Suppliers range | 1-(2,6-Dichloro-4-hydroxphenyl)-1,3-dihydroindol-2-one-13C6 is an intermediate in synthesizing 4-Hydroxy Diclofenac-13C6, a labelled metabolite of Diclofenac, which is a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C813C6H9Cl2NO2. US Biological Life Sciences. | Worldwide |
1-(2-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 1-(2-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester is an intermediate used to prepare 4-Dechloro-2-chloroindomethacin (D226240), an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). Group: Biochemicals. Grades: Highly Purified. CAS No. 1568-35-0. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H18ClNO4. US Biological Life Sciences. | Worldwide |
1-(2-Methylpropyl)-4-[(3RS)-3-[4(-2-methylpropyl)-phenyl]butyl]benzene Quick inquiry Where to buy Suppliers range | 1-(2-Methylpropyl)-4-[(3RS)-3-[4(-2-methylpropyl)-phenyl]butyl]benzene is an impurity in the synthesis of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C24H34, Molecular Weight: 322.529999999999. US Biological Life Sciences. | Worldwide |
12(S)-HHTrE Quick inquiry Where to buy Suppliers range | 12(S)-HHTrE is a product of the cyclooxygenase (COX) pathway and one of the primary arachidonic acid metabolites of human platelets. It is biosynthesized by thromboxane (TXA2) synthase from prostaglandin H2 (PGH2) concurrently with TXA2. Synonyms: 12(S)-HHT; 12-hydroxyheptadecatrienoic acid. Grades: ≥95%. CAS No. 54397-84-1. Molecular formula: C17H28O3. Mole weight: 280.4. | |
1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 1-(3,4-Dichlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester is an intermediate used to prepare 3-Chloroindomethacin (C367395), an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). Group: Biochemicals. Grades: Highly Purified. CAS No. 942431-82-5. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H17Cl2NO4, Molecular Weight: 406.26. US Biological Life Sciences. | Worldwide |
1-(3-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 1-(3-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid Methyl Ester is an intermediate used to prepare 4-Dechloro-3-chloroindomethacin (D226245), an impurity of Indomethacin (I641000) which inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). Group: Biochemicals. Grades: Highly Purified. CAS No. 1568-36-1. Pack Sizes: 10mg, 100mg. Molecular Formula: C20H18ClNO4. US Biological Life Sciences. | Worldwide |
1-(4-sec-Butylphenyl)ethanone Quick inquiry Where to buy Suppliers range | 1-(4-sec-Butylphenyl)ethanone is a useful synthetic intermediate in the synthesis of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 7645-81-0. Pack Sizes: 1g, 10g. Molecular Formula: C12H16O, Molecular Weight: 176.25. US Biological Life Sciences. | Worldwide |
15-Keto Prostaglandin E2 Quick inquiry Where to buy Suppliers range | 15-Keto Prostaglandin E2 is a lipid compound derived from arachidonic acid by the action of cyclooxygenases. Prostaglandins act locally as messenger molecules in a variety of physiological processes. Group: Biochemicals. Grades: Highly Purified. CAS No. 26441-05-4. Pack Sizes: 10mg, 25mg. Molecular Formula: C20H30O5, Molecular Weight: 350.45. US Biological Life Sciences. | Worldwide |
17-Phenyl-trinor-prostaglandin E2 Quick inquiry Where to buy Suppliers range | 17-Phenyl-trinor-prostaglandin E2 is a synthetic analog of PGE2 and an agonist at the EP1 and EP3 receptor (1). Prostaglandin E2(PGE2) regulates neuroinflammatory responses and is upregulated in brain injury by cyclooxygenase 2 (COX-?2) and membrane-bound PGE synthase. 17-Phenyl-trinor-prostaglandin E2 can be used to investigate inflammatory signaling pathways (2). Group: Biochemicals. Grades: Highly Purified. CAS No. 38315-43-4. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C23H30O5, Molecular Weight: 386.48. US Biological Life Sciences. | Worldwide |
1-?Bromononane Quick inquiry Where to buy Suppliers range | 1-?Bromononane is a useful synthetic intermediate. It is used in the synthesis of cyclooxygenase-2 (COX-2), a new class of selective COX-2 inactivators. It is also used to prepare alkylimidazoles by N-alkylation of imidazoles as antibacterial agents. Group: Biochemicals. Grades: Highly Purified. CAS No. 693-58-3. Pack Sizes: 1g, 5g. Molecular Formula: C9H19Br. US Biological Life Sciences. | Worldwide |
1-Ethyl-1,3,4,9-tetrahydro-8-(1-methylethyl)pyrano[3,4-b]indole-1-ethanol Quick inquiry Where to buy Suppliers range | SDX-309 is a potent indole-pyran analogs of SDX-101 (R-etodolac, E933090) which has anti-tumor activity unrelated to cyclooxygenase-2 inhibition. Group: Biochemicals. Grades: Highly Purified. CAS No. 849630-33-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H25NO2, Molecular Weight: 287.399999999999. US Biological Life Sciences. | Worldwide |
1-Hydroxy-o-carborane Quick inquiry Where to buy Suppliers range | 1-Hydroxy-o-carborane is a reactant used in the synthetic preparation of Asborin, which is the carbaborane analog of Aspirin, proved to be an active cyclooxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 23987-99-7. Pack Sizes: 10mg, 20mg. Molecular Formula: C2H12B10O, Molecular Weight: 160.229999999999. US Biological Life Sciences. | Worldwide |
1-Isopropyl Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 8-Ethyl-1,3,4,9-tetrahydro-1-(1-methylethyl)-Pyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 849630-65-5. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
1-Propyl Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1-Ethyl-1,3,4,9-tetrahydro-8-(1-methylethyl)-Pyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 57816-83-8. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid Quick inquiry Where to buy Suppliers range | 20-Hydroxy-(5Z,8Z,11Z,14Z)-eicosatetraenoic acid is a potent vasoconstrictor produced in vascular smooth muscle cells. Its EC50 value is < 10 nM. It is a cytochrome P450 metabolite. It induces diuresis by inhibiting Na+-K+-ATPase in proximal tubules and Na+/K+/Cl+ cotransporter in the thick ascending limb of Henle's loop in kidney. It is involved in the regulation of sodium, potassium, and chloride transport in the renal tubules. It is a vasoconstrictor that mediates pressure-induced autoregulatory vasoconstriction in rat cerebral microvessels. It is excreted mainly as the glucuronide conjugate. It can be further metabolized by cyclooxygenase to 20-hydroxy PGG2 and 20-hydroxy PGH2. It regulates blood pressure in a complex way. It sensitizes smooth muscle cells to the constrictor stimuli and promotes the proliferation of endothelial cells. It has the ability to induce proinflammatory changes. It blocked the 70 pS K+ channel localized in the apical membrane in TALH cells. It was found to be a potent vasoconstrictor through activating the kinase pathways that contribute to the vascular tone regulation including MAPK, PKC, rho kinase and src-type tyrosine kinase. It may similarly regulate blood pressure and contribute to the development of stroke and heart attacks. Synonyms: 20-Hydroxyeicosatetraeonic acid; 20 Hydroxyeicosatetraeonic acid; 20Hydroxyeicosatetraeonic acid; 20HETE; 20 HETE; 20-HETE;(5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid;20-Hydroxyeicosatetraenoic acid;20-hydroxy-5,8,11,14-eicosatetraenoic acid. Grades: >98%. CAS No. 79551-86-3. Molecular formula: C20H32O3. Mole weight: 320.47. | |
2-[2- (2, 6-Dichloro-4-hydroxphenylamino) phenyl-d4]-N, N-dimethylacetamide Quick inquiry Where to buy Suppliers range | 2-[2- (2, 6-Dichloro-4-hydroxphenylamino) phenyl-d4]-N, N-dimethylacetamide is an intermediate in the synthesis of 4-Hydroxy Diclofenac-d4 (H825227), is an isotope labeled metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1382084-40-3. Pack Sizes: 500ug, 5mg. Molecular Formula: C16H12D4Cl2N2O2, Molecular Weight: 343.24. US Biological Life Sciences. | Worldwide |
2,?2'-?[(3,?3',?5,?5'-Tetrachloro[1,?1'-?biphenyl]?-?4,?4'-?diyl)?diimino]?bis-benzeneacetic Acid Quick inquiry Where to buy Suppliers range | 2,?2'-?[(3,?3',?5,?5'-Tetrachloro[1,?1'-?biphenyl]?-?4,?4'-?diyl)?diimino]?bis-benzeneacetic Acid is an impurity of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound and a cyclooxygenase (COX) inhibitor (1,2,3). Diclofenac exhibits anti-inflammatory, analgesic, and antipyretic properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 1609187-32-7. Pack Sizes: 1mg, 5mg. Molecular Formula: C28H20Cl4N2O4, Molecular Weight: 590.28. US Biological Life Sciences. | Worldwide |
2-?[(2,?6-Dichloro-?4-?oxo-?2,?5-?cyclohexadien-?1-?ylidene)?amino]?-benzeneacetic Acid Quick inquiry Where to buy Suppliers range | 2-?[(2,?6-Dichloro-?4-?oxo-?2,?5-?cyclohexadien-?1-?ylidene)?amino]?-benzeneacetic Acid is a related compound of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound and a cyclooxygenase (COX) inhibitor (1,2,3). Diclofenac exhibits anti-inflammatory, analgesic, and antipyretic properties. 2-?[(2,?6-Dichloro-?4-?oxo-?2,?5-?cyclohexadien-?1-?ylidene)?amino]?-benzeneacetic Acid can be used to study cytochrome P 450 isoforms involved in the bioactivation of diclofenac to reactive p-benzoquinone imines (4). Group: Biochemicals. Grades: Highly Purified. CAS No. 928343-25-3. Pack Sizes: 500ug, 1mg. Molecular Formula: C14H9Cl2NO3, Molecular Weight: 310.13. US Biological Life Sciences. | Worldwide |
2-(2,6-Dichlorophenoxy)-N-phenylacetamide Quick inquiry Where to buy Suppliers range | 2-(2,6-Dichlorophenoxy)-N-phenylacetamide is a related compound of Diclofenac (D436450), a nonsteroidal anti-inflammatory compound and a cyclooxygenase (COX) inhibitor (1,2,3). Diclofenac exhibits anti-inflammatory, analgesic, and antipyretic properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 146607-19-4. Pack Sizes: 25mg, 50mg. Molecular Formula: C14H11Cl2NO2. US Biological Life Sciences. | Worldwide |
2-[ (2, 6-Dichlorophenyl) amino]benzaldehyde (Diclofenac impurity) Quick inquiry Where to buy Suppliers range | 13C Labeled Diclofenac Sodium Salt is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: N- (2, 6-Dichlorophenyl) anthranilaldehyde; 2- (2, 6-Dichloroanilino) benzaldehyde; o- (2, 6-Dichloroanilino) benzaldehyde; Diclofenac Aldehyde. Grades: Highly Purified. CAS No. 22121-58-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
2-[ (4-Acetylphenyl) methyl]cyclopentan-1-one Quick inquiry Where to buy Suppliers range | 2-[ (4-Acetylphenyl) methyl]cyclopentan-1-one is a possible metabolite of Loxoprofen (L472900, Na salt), a non-selective nonsteroidal anti-inflammatory drug (NSAID) that has been effective in reducing atherosclerosis in mice by reducing inflammation. It becomes active after metabolism in the body and inhibits the activation of cyclooxygenase. Group: Biochemicals. Grades: Highly Purified. CAS No. 96824-28-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C14H16O2, Molecular Weight: 216.28. US Biological Life Sciences. | Worldwide |
2- (4-Isobutylphenyl) propanal Quick inquiry Where to buy Suppliers range | 2- (4-Isobutylphenyl) propanal is an impurity of the drug Ibuprofen (I140000), a selective cyclooxygenase inhibitor that also inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 51407-46-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C13H18O, Molecular Weight: 190.28. US Biological Life Sciences. | Worldwide |
2,5-Dimethyl Celecoxib Quick inquiry Where to buy Suppliers range | A non-cyclooxygenase-2 inhibitor analog of Celecoxib. The celecoxib analog, 2,5-di-Me celecoxib (DMC), lacks COX-2 inhibitory activity but exhibits cytotoxic properties comparable to the COX-2 inhibitor Celecoxib. Group: Biochemicals. Alternative Names: 4-[5-(2,5-Dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; DMC. Grades: Highly Purified. CAS No. 457639-26-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
2-Amino-5-chloronicotinaldehyde Quick inquiry Where to buy Suppliers range | 2-Amino-5-chloronicotinaldehyde is an intermediate used to prepare benzopyrancarboxylates and quinolinecarboxylates as cyclooxygenase-2 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 54856-61-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C6H5ClN2O, Molecular Weight: 156.57. US Biological Life Sciences. | Worldwide |
2-Benzothiazolethiol Quick inquiry Where to buy Suppliers range | 2-Benzothiazolethiol is an intermediate used to synthesize benzothiazole derivatives as cyclooxygenase inhibitors. It is also used to prepare pyridinone derivatives as potent non-nucleoside human immunodeficiency virus type 1 specific reverse transcriptase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 149-30-4. Pack Sizes: 100mg, 5g. Molecular Formula: C7H5NS2. US Biological Life Sciences. | Worldwide |
2-Bromo-1-furan-2-yl-ethanone Quick inquiry Where to buy Suppliers range | 2-Bromo-1-furan-2-yl-ethanone is a reagent that is used in the preparation of diaryldi hydropyrrolizine derivatives and their activity as cyclooxygenase and lipoxygenase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 15109-94-1. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H5BrO2, Molecular Weight: 189.01. US Biological Life Sciences. | Worldwide |
2-Bromoethylcyclopropane Quick inquiry Where to buy Suppliers range | 2-Bromoethylcyclopropane is used as a reagent to synthesize 22-Hydroxycholesterol (H918010) derivatives, compounds that act as serum cholesterol lowering agents. 2-Bromoethylcyclopropane is also used to prepare pyridazinones, compounds that act as cyclooxygenase 2-inhibitors (they possess anti-inflammatory and antiangiogenic effects). Group: Biochemicals. Grades: Highly Purified. CAS No. 36982-56-6. Pack Sizes: 50mg, 100mg. Molecular Formula: C5H9Br. US Biological Life Sciences. | Worldwide |
2-Bromomethyl-6-nitrobenzoic Acid Methyl Ester Quick inquiry Where to buy Suppliers range | 2-Bromomethyl-6-nitrobenzoic Acid Methyl Ester is a potential cyclooxygenase inhibitor derived from thalidomide (T338850), an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma. Group: Biochemicals. Alternative Names: Methyl 2-(2-Bromomethyl)-6-nitrobenzoate; Methyl 2-(Bromomethyl)-6-nitrobenzoate. Grades: Highly Purified. CAS No. 61940-21-4. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
2-Chloro-6- (trifluoromethyl) aniline Quick inquiry Where to buy Suppliers range | 2-Chloro-6- (trifluoromethyl) aniline is a molecular determinant for the selective inhibition of cyclooxygenase-2 by lumiracoxib. Group: Biochemicals. Grades: Highly Purified. CAS No. 433-94-3. Pack Sizes: 1g, 5g. Molecular Formula: C7H5ClF3N, Molecular Weight: 195.57. US Biological Life Sciences. | Worldwide |
2-Cyano-3,3-diphenylacrylic Acid Quick inquiry Where to buy Suppliers range | 2-Cyano-3,3-diphenylacrylic Acid was used to study skin-permeable selective cyclooxygenaswe-2 inhibitor composition, and to study hydrophilic components of cosmetic compositions, such as in sunscreen. Group: Biochemicals. Grades: Highly Purified. CAS No. 10380-41-3. Pack Sizes: 100mg, 500mg. Molecular Formula: C16H11NO2, Molecular Weight: 249.26. US Biological Life Sciences. | Worldwide |
2-Ethoxyphenol Quick inquiry Where to buy Suppliers range | 2-Ethoxyphenol is used in the studies on the inhibition of oral bacteria by phenolic compounds. Studies on the prostagladins cyclooxygenase inhibition by phenolic compounds. Reagent for the stereoselective preparation of (arylthiomethyl) morpholines as selective norepinephrine reuptake inhibitors and dual serotonin / norepinephrine reuptake inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 94-71-3. Pack Sizes: 5g, 25g. Molecular Formula: C8H10O2, Molecular Weight: 138.16. US Biological Life Sciences. | Worldwide |
2-Hydroxyacetophenone Quick inquiry Where to buy Suppliers range | 2-Hydroxyacetophenone is a useful reactant for synthesis of diarylpyrazoles as cyclooxygenase 2 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 582-24-1. Pack Sizes: 5g, 25g. Molecular Formula: C8H8O2, Molecular Weight: 136.15. US Biological Life Sciences. | Worldwide |
2-Iodobenzotrifluoride Quick inquiry Where to buy Suppliers range | 2-Iodobenzotrifluoride acts as a reagent in the preparation, cyclooxygenase-1 inhibitory activity, and docking studies of aminoalkoxyphenyl benzamide s. Prepartion and SAR of tricyclic 4,4-dimethyl-3,4-dihydrochromeno[3,4-d]imidazole derivatives as microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 444-29-1. Pack Sizes: 1g, 5g. Molecular Formula: C7H4F3I, Molecular Weight: 272.01. US Biological Life Sciences. | Worldwide |
2-Methyl-Celecoxib Quick inquiry Where to buy Suppliers range | 2-Methyl-Celecoxib is an analog of the anti-inflammatory drug Celecoxib (C251000). Celecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 170570-09-9. Pack Sizes: 10mg, 25mg. Molecular Formula: C18H16F3N3O2S, Molecular Weight: 395.4. US Biological Life Sciences. | Worldwide |
2-Oleoyl glycerol Quick inquiry Where to buy Suppliers range | 2-Oleoyl glycerol (2-OG) is a natural monoacylglycerol with an 18:1 oleoyl group at the sn-2 position of glycerol. 2-OG, like 2-arachidonoyl glycerol, is metabolized by monoacylglycerol lipase, but, unlike 2-AG, it is not metabolized by cyclooxygenases or lipoxygenases. Synonyms: 2-Monoolein; 2-OG; 2-Monooleoylglycerol; 2-Glyceryl monooleate; Glyceryl 2-oleate; 2-(9Z-octadecenoyl)-sn-glycerol. Grades: >99%. CAS No. 3443-84-3. Molecular formula: C21H40O4. Mole weight: 356.54. | |
2-(p-sec-Butylphenyl)propionic Acid Quick inquiry Where to buy Suppliers range | 2-(p-sec-Butylphenyl)propionic Acid (Ibuprofen EP Impurity O) is an impurity of Ibuprofen (I140000); a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 64451-76-9. Pack Sizes: 250mg, 2.5g. Molecular Formula: C13H18O2, Molecular Weight: 206.28. US Biological Life Sciences. | Worldwide |
2-(p-sec-Butylphenyl)propionic Acid-d3 Quick inquiry Where to buy Suppliers range | 2-(p-sec-Butylphenyl)propionic Acid-d3 is the isotope labelled analog of 2-(p-sec-Butylphenyl)propionic Acid (B692720); an impurity of Ibuprofen (I140000) which is a selective cyclooxygenase inhibitor (IC50=14.9uM) that inhibits PGH synthase-1 and PGH synthase-2 with comparable potency. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C13H15D3O2, Molecular Weight: 209.3. US Biological Life Sciences. | Worldwide |
3-(4-Methylphenyl)-5-(trifluoromethyl)-1H-pyrazole Quick inquiry Where to buy Suppliers range | An impurity of Celecoxib, a cyclooxygenase 2 inhibitor. Synonyms: 3-(4-methylphenyl)-5-(trifluoromethyl)pyrazole; 3-(Trifluoromethyl)-5-p-tolyl-1H-pyrazole; 3-(p-Tolyl)-5-(trifluoromethyl)-1H-pyrazole. Grades: 95 %. CAS No. 219986-64-8. Molecular formula: C11H9F3N2. Mole weight: 226.2. | |
3-(7-Ethyl-3-(2-hydroxyethyl)-1H-indol-2-yl)pent-2-enoic Acid Quick inquiry Where to buy Suppliers range | 3-(7-Ethyl-3-(2-hydroxyethyl)-1H-indol-2-yl)pent-2-enoic Acid is a a double bond isomer of Etodolac Impurity L which is an impurity of Etodolac (racemic, E933100), a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). Etodolac displays anti-inflammatory effects in both adjuvant arthritic and normal rats. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C17H21NO3, Molecular Weight: 287.35. US Biological Life Sciences. | Worldwide |
4-(2-Aminoanilino)pyridine Quick inquiry Where to buy Suppliers range | An intermediate used to prepare Timiperone as well as cyclooxygenase-2 inhibitors and adrenergic agents. Group: Biochemicals. Alternative Names: N1-4-Pyridinyl-1,2-benzenediamine; NSC 155702. Grades: Highly Purified. CAS No. 65053-26-1. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
4-(2-Aminoanilino)pyridine-d4 Quick inquiry Where to buy Suppliers range | An intermediate used to prepare labeled Timiperone as well as cyclooxygenase-2 inhibitors and adrenergic agents. Group: Biochemicals. Alternative Names: N1-4-Pyridinyl-1,2-benzenediamine-d4; NSC 155702-d4. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
4-Desmethyl-3-methyl Celecoxib Quick inquiry Where to buy Suppliers range | A meta positional isomer of Celecoxib with selective inhibitory activity against human cyclooxygenase-2. Group: Biochemicals. Alternative Names: 4-[5-(3-Methylphenyl)-3-trifluoromethyl-1H-pyrazol-1-yl]benzenesulfonamide. Grades: Highly Purified. CAS No. 170570-01-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
4-Hydroxy Diclofenac Quick inquiry Where to buy Suppliers range | A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound an cyclooxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 64118-84-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
4-Hydroxy Diclofenac-13C6 (contain 3% unlabeled) Quick inquiry Where to buy Suppliers range | 13C Labeled Diclofenac Sodium Salt is a known nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor. Group: Biochemicals. Alternative Names: 2-[ (2, 6-Dichloro-4-hydroxyphenyl)amino] (benzene-13C6)acetic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
4-(NITROOXY)BUTYL (2S)-2-(6-METHOXY-2-NAPHTHYL)PROPANOATE Quick inquiry Where to buy Suppliers range | Naproxcinod, a nitro compound, has been found to be a nitric oxide donor as well as a cyclooxygenase inhibitor that was once studied aginast duchenne muscular dystrophy. Uses: Nitric oxide donors. Synonyms: Naproxcinod; Nitronaproxen; HCT 3012; HCT3012; HCT-3012; AZD 3582; AZD3582; AZD-3582; Naproxen-n-butyl nitrate; 4-nitrooxybutyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate. Grades: 98%. CAS No. 163133-43-5. Molecular formula: C18H21NO6. Mole weight: 347.36. | |
5-Hydroxy Diclofenac Quick inquiry Where to buy Suppliers range | A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound an cyclooxygenase (COX) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 69002-84-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
5-Methyl-3,4-diphenyl-4,5-dihydroisoxazol-5-ol Quick inquiry Where to buy Suppliers range | An intermediate for the preparation of Valdecoxib. Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of osteoarthritis, rheumatoid arthritis, etc. Valdecoxib exhibits a selectively inhibitory effect of cyclooxygenase-2. Uses: Intermediate for the preparation of valdecoxib. Synonyms: 4,5-Dihydro-5-methyl-3,4-diphenyl-5-isoxazolol. CAS No. 181696-73-1. Molecular formula: C16H15NO2. Mole weight: 253.30. | |
6-Cyano-2-methylpyridine Quick inquiry Where to buy Suppliers range | Intermediate in the preparation of selective cyclooxygenase-2 inhibitors and calcium antagonists. Group: Biochemicals. Alternative Names: 6-Methyl-2-pyridinecarbonitrile; 2-Methyl-6-cyanopyridine; 6-Cyano-2-methylpyridine; 6-Methyl-2-cyanopyridine; 6-Methyl-2-pyridinecarbonitrile; 6-Methylpicolinonitrile; NSC 26022. Grades: Highly Purified. CAS No. 1620-75-3. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
6-Hydroxy Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1,8-Diethyl-1,3,4,9-tetrahydro-6-hydroxypyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 101901-06-8. Molecular formula: C17H21NO4. Mole weight: 303.36. | |
8-Isopropyl Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1-Ethyl-1,3,4,9-tetrahydro-8-(1-methylethyl)-pyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 57917-63-2. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
8-Propyl Etodolac Quick inquiry Where to buy Suppliers range | A derivative of Etodolac. Etodolac is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2. Synonyms: 1-Ethyl-1,3,4,9-tetrahydro-8-propyl-pyrano[3,4-b]indole-1-acetic Acid. Grades: > 95%. CAS No. 57817-27-3. Molecular formula: C18H23NO3. Mole weight: 301.39. | |
Acetylsalicylic Acid Impurity E Quick inquiry Where to buy Suppliers range | Sasapyrine (salsalate) is a nonsteroidal oral anti-inflammatory agent.Relative to other NSAIDs, salsalate has a weak inhibitory effect on the cyclooxygenase enzyme and decreases the production of several pro inflammatory chemical signals such as interleukin-6, TNF-alpha, and C-reactive protein. Synonyms: NSC-49171. Grades: >98%. CAS No. 552-94-3. Molecular formula: C14H10O5. Mole weight: 258.23. | |
AKR1C3 Inhibitor (3- (4- (Trifluoromethyl) phenylamino) benzoic Acid) Quick inquiry Where to buy Suppliers range | A cell-permeable 3-phenyl-aminobenzoate compound that acts as a potent, competitive, reversible, active-site targeting inhibitor of aldo-keto reductase 1C3 (AKR1C3; type 5 17b-hydroxysteroid dehydrogenase) (IC50 = 60nM) with excellent selectivity over other closely related human AKR isoforms (IC50 = 22.7, 15.4, 62.7, >50, and >50uM for and AKR1C1, AKR1C2, AKR1C4, AKR1B1 and AKR1B10, respectively. Exhibits a weak inhibitory effect on cyclooxygenase 1 and 2 (IC50 = 100uM). Shown to efficiently block the AKR1C3-mediated production of testosterone in LNCaP-AKR1C3 cells (~10uM). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Ampiroxicam Quick inquiry Where to buy Suppliers range | Ampiroxicam is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug. Synonyms: CP 65703; CP65703; CP-65703. Grades: >98%. CAS No. 99464-64-9. Molecular formula: C20H21N3O7S. Mole weight: 447.46. | |
Apricoxib Quick inquiry Where to buy Suppliers range | Apricoxib is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. Synonyms: CS-701; CS 701; CS701; TG01; TG 01; TG-01; R-109339, R 109339; R109339; Benzenesulfonamide, 4-[2-(4-ethoxyphenyl)-4-methyl-1H-pyrrol-1-yl]-. CAS No. 197904-84-0. Molecular formula: C19H20N2O3S. Mole weight: 356.44. | |
Asiaticoside Quick inquiry Where to buy Suppliers range | Antibacterial. Human collagen I synthesis inducer. Anti-wrinkle activity. Shows wound healing activity. Enhances normal human skin cell migration, attachment and growth. Suppresses collagen expression and TGF-beta/Smad signaling by inducing Smad7 and inhibiting TGF-betaRI and TGF-betaRII. Anti-inflammatory. Anti-gastric ulcer. Mitogen-activated protein kinases (MAPKs), nuclear factor-kappaB (NF-kappaB), cyclooxygenase-2 (COX-2) and inducible nitric oxide synthase (iNOS; NOSII) expression, production of serum tumor necrosis factor (TNF-alpha) and interleukin-6 (IL-6) inhibitor. Apoptosis inducer in cancer cells. Enhances antitumor activity of vincristine in cancer cells. Might be useful in cancer chemotherapy. Anxiolytic. Antidepressant-like activity. Hepatoprotective effects. CYP2C19 and CYP3A4 inhibitor. Neuroprotective. Antileishmanial activity. cPLA2 and sPLA2 inhibitor. Group: Biochemicals. Alternative Names: Blastostimulina, Centelase, Emdecassol, Madecassol, Marticassol, FK1080, BRN 0078195, NSC 166062. Grades: Highly Purified. CAS No. 16830-15-2. Pack Sizes: 10mg, 50mg. Molecular Formula: C48H78O19. US Biological Life Sciences. | Worldwide |
Avarol Quick inquiry Where to buy Suppliers range | Antibacterial against selected Gram-positive strains, antifungal. Anticancer compound. Antileukemic. Antimitotic agent. Antiviral compound. Inhibits HIV activity. Anti-inflammatory. Synovial phospholipase A2, cyclooxygenase and lipoxygenase inhibitor. Modulator of superoxide dismutase and glutathione peroxidase. Platelet aggregation inhibitor. Anti-psoriatic, mediated by inhibition of TNF-alpha generation and NF-kappaB activation. Group: Biochemicals. Alternative Names: NSC 306951. Grades: Highly Purified. CAS No. 55303-98-5. Pack Sizes: 1mg. Molecular Formula: C21H30O2. US Biological Life Sciences. | Worldwide |
Berberine Hydrochloride Quick inquiry Where to buy Suppliers range | An isoqinoline alkaloid shown to have a chemopreventive property against colon tumor formation by inhibiting the enzyme cyclooxygenase-2 (cox-2) which is abundantly expressed in colon cancer cells. Also inhibits Activator Protein 1 (AP-1), a transcription factor that plays a critical role in inflammation and carcinogenesis. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs. Group: Biochemicals. Alternative Names: 5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium Chloride; Berberine Chloride; 7, 8, 13, 13a-Tetradehydro-9, 10-dimethoxy-2, 3- (methylenedioxy) berbinium Chloride; Berberine Hydrochloride; NSC 646666. Grades: Highly Purified. CAS No. 633-65-8. Pack Sizes: 25g. US Biological Life Sciences. | Worldwide |
BW 755C Quick inquiry Where to buy Suppliers range | Constitutive cyclooxygenase (COX-1) is present in cells under physiological conditions, whereas COX-2 is induced by some cytokines, mitogens, and endotoxin in pathological conditions, such as inflammation. Since 5-lipoxygenase (5-LO) oxidizes arachidonic acid to 5-hydroperoxyeicosatetraenoic acid. BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways. It inhibits 5-LO with IC50s of 0.75 μM, COX-1 with IC50s of 0.65 μg/ml, and COX-2 with IC50s of 1.2 μg/ml. BW 755C may also inhibit other LO pathways in vivo. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: BW755C; BW-755C; 1H-Pyrazol-3-amine, 4,5-dihydro-1-[3-(trifluoromethyl)phenyl]-; 4,5-Dihydro-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-amine; 1-(3-Trifluoromethylphenyl)-4,5-dihydro-1H-pyrazol-3-amine; 3-Amino-1-[3-(trifluoromethyl)phenyl]-2-pyrazoline; 3-Amino-1-[3-(trifluoromethyl)phenyl]pyrazoline; 3-Amino-1-[m-(trifluoromethyl)phenyl]-2-pyrazoline; Compound BW 755C. Grades: ≥95%. CAS No. 66000-40-6. Molecular formula: C10H10F3N3. Mole weight: 229.20. | |
Celecoxib Quick inquiry Where to buy Suppliers range | Celecoxib is a COX-2 inhibitor and nonsteroidal anti-inflammatory drug (NSAID) used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis. Uses: Cyclooxygenase 2 inhibitors. Synonyms: Celebra; Celebrex; SC 58635; Benzenesulfonamide, 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-; 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; 4-[5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; Celecox; Celocoxib; Eurocox; Medicoxib; Onsenal; Xilebao; YM 177. Grades: ≥95%. CAS No. 169590-42-5. Molecular formula: C17H14F3N3O2S. Mole weight: 381.37. | |
Celecoxib Impurity 2 Quick inquiry Where to buy Suppliers range | An impurity of celecoxib, a cyclooxygenase 2 inhibitor. Synonyms: 1H-Pyrazole, 5-(4-methylphenyl)?-3-(trifluoromethyl)?-; 5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(p-Tolyl)-3-(trifluoromethyl)-1H-pyrazole; 5-(4-Methylphenyl)-3-trifluoromethyl-1H-pyrazole; Celecoxib Impurity H. Grades: > 95%. CAS No. 948293-46-7. Molecular formula: C11H9F3N2. Mole weight: 226.2. | |
Chelerythrine chloride Quick inquiry Where to buy Suppliers range | Cell permeable potent inhibitor of protein kinase C. Does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase or calcium/calmodulin-dependent protein kinase. Antiplatelet, anti-inflammatory, antibacterial and antitumor compound. Apoptosis inducer in cancer cells in vitro and in vivo. Activates MAPK and JUNK signaling pathways. Affects translocation of PKC from cytosol to plasma membrane. Neurite outgrowth stimulator. Inhibits binding of BclXL to Bak (IC50 =1.5uM) or Bad proteins and stimulates apoptosis in several cancer cell lines. Blocks human P2X7 receptor. Induces cell cycle arrest in G1 phase. Specific cyclooxygenase-2 inhibitor. Group: Biochemicals. Alternative Names: NSC 36405, 1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride. Grades: Highly Purified. CAS No. 3895-92-9. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C21H18ClNO4. US Biological Life Sciences. | Worldwide |
Cinnamtannin B-1 (Epicatechin-(4beta?8,2beta?O?7)-epicatechin-(4alpha?8)-epicatechin, Cinnamtannin B1, CB1) Quick inquiry Where to buy Suppliers range | A-Type proanthocyanidine. Selective cytotoxic agent. Potent antioxidant. Lipid peroxidation inhibitor. Antidiabetic, with similar effects to insulin activity in adipogenesis. Free radical scavenger. Antithrombotic. Inhibits platelet aggregation. Apoptosis inhibitor. Reduces intracellular Ca(2+) overload and ROS production. Antibacterial. Cyclooxygenase-2 (COX-2) inhibitor in vitro. LDL oxidation inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 88082-60-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Clematomandshurica saponin B Quick inquiry Where to buy Suppliers range | Clematomandshurica saponin B is a triterpenoid saponin isolated from the roots and rhizomes of Clematis mandshurica with inhibitory effect against cyclooxygenase-2. Synonyms: CLEMATOMANDSHURICA SAPONIN B; 916649-91-7; Clamatomandshurica saponin BHY-N4230; CS-0032478. Grades: >98%. CAS No. 916649-91-7. Molecular formula: C92H142O46. Mole weight: 1984.1. | |
CP 461 Quick inquiry Where to buy Suppliers range | CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP 461; CP-461; CP461; OSI 461; UNII-68OJX9I7DT. N-benzyl-2-[6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide;hydrochloride; CAS: 227619-92-3 (CP-461 free base). Grades: >98%. CAS No. 227619-96-7. Molecular formula: C25H22ClFN2O. Mole weight: 420.91. | |
CP-461 free base Quick inquiry Where to buy Suppliers range | CP 461, belonging to a class of novel proapoptotic drugs with antineoplastic effect, specifically inhibit cyclic GMP phosphodiesterases but not cyclooxygenase-1 or -2. Synonyms: CP-461 free base; CP 461 free base; CP461 free base; N-benzyl-2-[(3Z)-6-fluoro-2-methyl-3-(pyridin-4-ylmethylidene)inden-1-yl]acetamide; UNII-824ZMS3BGL; OSI-461 free base. Grades: >98%. CAS No. 227619-92-3. Molecular formula: C25H21FN2O. Mole weight: 384.45. |