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Cyclopenin Cyclopenin is one of an unusual family of benzodiazepine metabolites produced by a number of Penicllium species. Often mistakenly referred to as a mycotoxin, cyclopenin shows little toxicity against mammalian cells, bacteria or fungi in vitro. Cyclopenin is an intermediate in the biosynthesis of 3-O-methyl viridicatin, a strong inhibitor of the tumor necrosis factor alpha (TNF)-induced replication of human immunodeficiency virus (HIV). Lack of availability has hitherto restricted a more intensive investigation of this interesting metabolite. Group: Biochemicals. Grades: Highly Purified. CAS No. 19553-26-5. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 1
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Cyclopenin It is produced by the strain of Penicillum cyclopium and Pen. corymbiferum. Cyclopenin can inhibit the growth of plants. Cyclopenin acts as an inhibitor of acetylcholinesterase (AChE). Cyclopenin also has antibacterial activity against E. coli and M. pyogenes. Synonyms: (-)-Cyclopenine; (-)-Cyclopenin; Cyclopenine; (3S,3'R)-4-Methyl-3'-phenylspiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione; Spiro(3H-1,4-benzodiazepine-3,2'-oxirane)-2,5(1H,4H)-dione, 4-methyl-3'-phenyl-, cis-(-)-(9CI)-. Grades: ≥99%. CAS No. 20007-87-8. Molecular formula: C17H14N2O3. Mole weight: 294.30. BOC Sciences 5
(±)-Cyclopenin (±)-Cyclopenin is produced by a benzodiazepine metabolite produced by Penicillium. It is almost non-toxic to mammalian cells, bacteria or fungi in vitro. Synonyms: Spiro[3H-1,4-benzodiazepine-3,2'-oxirane]-2,5(1H,4H)-dione, 4-methyl-3'-phenyl-, (2'R,3'R)-rel-. Grades: >99% by HPLC. CAS No. 19553-26-5. Molecular formula: C17H14N2O3. Mole weight: 294.30. BOC Sciences 5
Viridicatin Viridicatin is a fungal metabolite produced by several species of Penicillium and formed by the rearrangement of the benzodiazepine, cyclopenin. Viridicatin exhibits potent selective activity against Mycobacterium tuberculosis but is inactive against most other bacteria. Group: Biochemicals. Alternative Names: 2,3-dihydroxy-4-phenylquinoline. Grades: Highly Purified. CAS No. 129-24-8. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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