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| Product | Description | |
|---|---|---|
| Cytochalasin e | Cytochalasin E, an epoxide containing Aspergillus-derived fungal metabolite, inhibits angiogenesis and tumor growth. Cytochalasin E is a potent actin depolymerization agent, and it binds and caps the barbed end of actin filaments to prevent actin elongation. Group: Inhibitors. Alternative Names: (7s,13e,16s,18r,19e)-18-dimethyl-10-phenyl;21,23-dioxa(13)cytochalasa-13,19-diene-1,17,22-trione,6,7-epoxy-18-hydroxy-16,;6,7-epoxy-10-phenyl-5,6,16,18-tetramethyl-21,23-dioxa-[13]cytochalas-13,19-die;CYTOCHALASIN 3;CYTOCHALASIN E;CYTOCHALASIN E, ASPERGI. CAS No. 36011-19-5. Molecular formula: C28H33NO7. Mole weight: 495.56. Appearance: white powder. Purity: >98%. IUPACName: CYTOCHALASIN E. Canonical SMILES: CC1CC=CC2C3C (O3) (C (C4C2 (C (=O)NC4CC5=CC=CC=C5)OC (=O)OC=CC (C1=O) (C)O)C)C. Density: 1.3 g/cm³. ECNumber: 252-835-7. Catalog: ACM36011195. |  |
| Cytochalasin E | Cytochalasin E is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins resulting in pronounced morphogenic changes in animals and plants. Despite this common mode of action, within the class there is evidence that individual members display diverse selectivity. Specifically, cytochalasin E acts as an angiogenesis inhibitor and, unlike other cytochalasins, is unable to inhibit glucose transport. Group: Biochemicals. Grades: Highly Purified. CAS No. 36011-19-5. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Cytochalasin E | It is produced by the strain of Rosellina necatrix. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: (7S,13E,16S,18R,19E)-6,7-Epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-21,23-Dioxa[13]cytochalasa-13,19-diene-1,17,22-trione; NSC 175151; [4S-(1E, 4R*, 6S*, 7E, 11aR*, 14R*, 14aR*, 15R*, 15aS*, 16aR*, 16bR*)]-3, 13, 14, 14a, 15, 15a, 16a, 16b-Octahydro-6-hydroxy-4, 6, 15, 15a-tetramethyl-14-(phenylmethyl)-[1, 3]Dioxacyclotridecino[4, 5-d]oxireno[f]isoindole-5, 10, 12(4H, 6H)-trione. Grades: >99% by HPLC. CAS No. 36011-19-5. Molecular formula: C28H33NO7. Mole weight: 495.56. |  |
| 19,20-Epoxycytochalasin C | 19,20-Epoxycytochalasin C is a major component of the cytochalasin complex from MST-FP1762. Although reported in the literature, there is no available biological data on the metabolite other than in-house data suggesting the presence of the epoxide renders the metaboltie more active than cytochalasin C in inhibition of tumor cell growth in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 189351-79-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 19,20-Epoxycytochalasin C | It is a fungal metabolite originally isolated from Nemania sp. UM10M. It is a major component of the cytochalasin complex. It inhibits tumour cell growth in vitro and inhibits the growth of chloroquine-sensitive and -resistant strains of P. falciparum. Synonyms: (3S, 3aR, 4E, 7S, 9R, 9aR, 10aS, 11S, 11aR, 14S, 14aR)-11-(acetyloxy)-6, 7, 9, 9a, 10a, 11, 14, 14a-octahydro-3, 9-dihydroxy-1, 2, 7, 9-tetramethyl-14-(phenylmethyl)-3H-oxireno[9, 10]cycloundec[1, 2-d]isoindole-8, 12(3aH, 13H)-dione. Grades: >99% by HPLC. CAS No. 189351-79-9. Molecular formula: C30H37NO7. Mole weight: 523.62. | |
| 19,20-Epoxycytochalasin D | 19,20-Epoxycytochalasin D is a major component of the cytochalasin complex from MST-FP1762. Although reported in the literature, there is no available biological data on the metabolite other than in-house data suggesting the presence of the epoxide renders the metabolite more active than cytochalasin D in inhibition of tumor cell growth in vitro. Group: Biochemicals. Grades: Highly Purified. CAS No. 191349-10-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 19,20-Epoxycytochalasin D | It is a fungal metabolite originally isolated from Nemania sp. UM10M. It is a major component of the cytochalasin complex. It inhibits tumour cell growth in vitro. It is active against the chloroquine-sensitive and -resistant strains of P. falciparum. Synonyms: (1S, 3S, 3aR, 4E, 7S, 9R, 9aR, 10aS, 11S, 11aR, 14S, 14aR)-11-(Acetyloxy)-3, 3a, 6, 7, 9, 9a, 10a, 11, 14, 14a-decahydro-3, 9-dihydroxy-1, 7, 9-trimethyl-2-methylene-14-(phenylmethyl)-1H-oxireno[9, 10]cycloundec[1, 2-d]isoindole-8, 12(2H, 13H)-dione; [1aS-(1aR*, 2R*, 2aS*, 5R*, 5aS*, 6R*, 8R*, 8aS*, 9E, 12R*, 14S*, 14aS*)]-2-(Acetyloxy)-5, 5a, 6, 7, 8, 8a, 11, 12, 14, 14a-decahydro-8, 14-dihydroxy-6, 12, 14-trimethyl-7-methylene-5-(phenylmethyl)-2H-oxireno[9, 10]cycloundec[1, 2-d]isoindole-3, 13(1aH, 4H)-dione. Grades: >99% by HPLC. CAS No. 191349-10-7. Molecular formula: C30H37NO7. Mole weight: 523.62. | |
| Cytochalasin H (Kodocytochalasin 1, Paspalin P1, 17-Deoxo-21-acetyl-zygosporin D) | Cytochalasin H is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins resulting in pronounced morphogenic changes in animals and plants. In vitro, cytochalasin H exhibits antibacterial, antifungal, nematocidal and antitumor activity. Group: Biochemicals. Alternative Names: Kodocytochalasin 1, Paspalin P1, 17-Deoxo-21-acetyl-zygosporin D. Grades: Highly Purified. CAS No. 53760-19-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cytochalasin J (Kodocytochalasin 2, Paspalin P11, Deacetylcytochalasin H, 17-Deoxo-zygosporin D) | Cytochalasin J is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins which give rise to pronounced morphogenic activity in animals and plants. Cytochalasin J is the deacetyl analogue of cytochalasin H and exhibits similar, though less potent, antibacterial, antifungal, nematocidal and antitumor activities. Group: Biochemicals. Alternative Names: Kodocytochalasin 2, Paspalin P11, Deacetylcytochalasin H, 17-Deoxo-zygosporin D. Grades: Highly Purified. CAS No. 56144-22-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| [(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonic Acid Diethyl Ester | [(2E,4E)-4-Methyl-2,4-hexadienyl]phosphonic Acid Diethyl Ester is a reactant used in the preparation of cytochalasin. Group: Biochemicals. Alternative Names: (E,E)-(4-Methyl-2,4-hexadienyl)-phosphonic Acid Diethyl Ester. Grades: Highly Purified. CAS No. 104701-95-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Chaetoglobosin A (NSC366739, BRN1097707) | Antibiotic. Cytochalasin analog with anti-fungal activity. Phytotoxic and anti-bacterial activity. Exhibits cytotoxic effects against human cancer cell lines. Enhances fibrinolytic activity of bovine aortic endothelial cells. Mycotoxin. Group: Biochemicals. Grades: Highly Purified. CAS No. 50335-03-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Cytochalasin A | Cytochalasin A is one of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins which give rise to pronounced morphogenic activity in animals and plants. Like most cytochalsins, cytochalasin A exhibits potent inhibition of actin filament function leading to cell death by apoptosis and displays a broad range of resultant cellular actions. Despite the common mode of action, there is evidence that individual members of this class display diverse selectivity. Specifically, cytochalasin A was shown to be one of the few cytochalasins exhibiting activity against HIV-1 protease. Group: Biochemicals. Grades: Highly Purified. CAS No. 14110-64-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cytochalasin A | It is produced by the strain of Helminthosporium dematioideum, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytochalasin A is an HIV protease inhibitor. Synonyms: NSC174119; Dehydrophomin; 5-Dehydrophomin; 5,5-Didehydrophomin; 2H-Oxacyclotetradecino(2,3-d)isoindole-2,5,18-trione, 6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-16-(phenylmethyl)-, (3E, 9R, 11E, 12aS, 13S, 15S, 15aS, 16S, 18aS)-; (7S,13E,16R,21E)-7-Hydroxy-16-methyl-10-phenyl-24-Oxa[14]cytochalasa-6(12),13,21-triene-1,20,23-trione; 16-Benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-13-hydroxy-9,15-dimethyl-14-methylene-2H-Oxacyclotetradecino[2,3-d]isoindole-2,5,18-trione. Grades: >98% by HPLC. CAS No. 14110-64-6. Molecular formula: C29H35NO5. Mole weight: 477.59. | |
| Cytochalasin B | Cytochalasin B is a cell-permeable mycotoxin binding to the barbed end of actin filaments, disrupting the formation of actin polymers, with K d value of 1.4-2.2 nM for F-actin. Cytochalasin B blocks cell migration. Uses: Scientific research. Group: Natural products. Alternative Names: Phomin. CAS No. 14930-96-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-16928. |  |
| Cytochalasin B | Cytochalasin B is one of the most extensively studied members of a family of potent mycotoxins produced by several species of fungi. All members of the class exhibit profound effects on cytoskeletal proteins which give rise to pronounced morphogenic activity in animals and plants. Like most cytochalsins, cytochalasin B exhibits potent inhibition of actin filament function leading to cell death by apoptosis and displays a broad range of resultant cellular actions. Despite the common mode of action, class there is evidence that individual members of this class display diverse selectivity. However, lack of comparative co-metabolite analysis has restricted a more complete understanding of their individual selectivity. Group: Biochemicals. Grades: Highly Purified. CAS No. 14930-96-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cytochalasin C | Cytochalasin C is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins resulting in pronounced morphogenic changes in animals and plants. The cytochalasins act by disrupting actin microfilaments and these effects are most noticeable by the inhibition of cell division. Group: Biochemicals. Grades: Highly Purified. CAS No. 22144-76-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Cytochalasin D | Cytochalasin D (Zygosporin A) is a potent actin polymerization inhibitor, could be derived from fungus. Cytochalasin D has cell-permeable activity. Cytochalasin D inhibits the G-actin - cofilin interaction by binding to G-actin. Cytochalasin D also inhibits the binding of cofilin to F-actin and decreases the rate of both actin polymerization and depolymerization in living cells. Cytochalasin D can reduce exosome release, in turn reducing the amount of survivin present in the tumour environment. Cytochalasin D induces phosphorylation and cytoplasmic retention of Yap [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. Alternative Names: Zygosporin A; NSC 209835. CAS No. 22144-77-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N6682. | |
| Cytochalasin D | It is produced by the strain of Metarrhizium anisopliae, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Uses: Anti-hypertensive. Synonyms: (3S, 3aR, 4S, 6S, 6aR, 7E, 10S, 12R, 13E, 15R, 15aR)-15-(Acetyloxy)-3, 3a, 4, 5, 6, 6a, 9, 10, 12, 15-decahydro-6, 12-dihydroxy-4, 10, 12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindole-1, 11(2H)-dione; (7S,13E,16S,18R,19E,21R)-[11]21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenylcytochalasa-6(12),13,19-triene-1,17-dione; (-)-Cytochalasin D; 1H-Cycloundec[d]isoindole-1,11(2H)-dione, 15-(acetyloxy)-3,3a,4,5,6,6a,9,10,12,15-decahydro-6,12-dihydroxy-4,10,12-trimethyl-5-methylene-3-(phenylmethyl)-, [3S-(3R*, 3aS*, 4R*, 6R*, 6aS*, 7E, 10R*, 12S*, 13E, 15S*, 15aS*)]-; NSC 209835; Zygosporin A; Cytohalasin D; Lygosporin A. Grades: >98%. CAS No. 22144-77-0. Molecular formula: C30H37NO6. Mole weight: 507.62. | |
| Cytochalasin H | It is produced by the strain of Pestalotia sp. AB 1942R-114. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytosine H has immunosuppressive effects. Synonyms: (7S,13E,16S,18R,19E,21R)-21-(Acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-[11]Cytochalasa-6(12),13,19-trien-1-one; (3S, 3aR, 4S, 6S, 6aR, 7E, 10S, 12R, 13E, 15R, 15aR)-15-(Acetyloxy)-2, 3, 3a, 4, 5, 6, 6a, 9, 10, 11, 12, 15-dodecahydro-6, 12-dihydroxy-4, 10, 12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; Cytochalasin H; Kodocytochalasin 1; Paspalin P I; [3S-(3R*, 3aS*, 4R*, 6R*, 6aS*, 7E, 10R*, 12S*, 13E, 15S*, 15aS*)]-15-(Acetyloxy)-2, 3, 3a, 4, 5, 6, 6a, 9, 10, 11, 12, 15-dodecahydro-6, 12-dihydroxy-4, 10, 12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; Paspalin; SC 305222; NSC305222; NSC-305222; (11)Cytochalasa-6(12),13,19-trien-1-one; phenyl-(11)cytochalasa-6(12),13,19-triene-1-one. Grades: >95% by HPLC. CAS No. 53760-19-3. Molecular formula: C30H39NO5. Mole weight: 493.63. | |
| Cytochalasin J | It is produced by the strain of Pestalotia sp. AB 1942R-114. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytosine J has immunosuppressive effects. Synonyms: Deacetylcytochalasin H; Kodocytochalasin 2; Paspalin P II; [3S-(3R*, 3aS*, 4R*, 6R*, 6aS*, 7E, 10R*, 12S*, 13E, 15S*, 15aS*)]-2, 3, 3a, 4, 5, 6, 6a, 9, 10, 11, 12, 15-Dodecahydro-6, 12, 15-trihydroxy-4, 10, 12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; (7S,13E,16S,18R,19E,21R)-7,18,21-Trihydroxy-16,18-dimethyl-10-phenyl-[[11]cytochalasa-6(12),13,19-trien-1-one. Grades: ≥ 95%. CAS No. 56144-22-0. Molecular formula: C28H37NO4. Mole weight: 451.60. | |
| Dihydrocytochalasin B | Dihydrocytochalasin B, a sort of mycotoxin derivative, has been found to restrain actin polymerization as well as mitosis. Uses: Cytochalasins are used as tools in cytological research, and in the field of actin polymerisation. Synonyms: 7(S),20(R)-Dihydroxy-16(R)-methyl-10-phenyl-24-oxa(14)cytochalasa-6(12),13(E)-diene-1,23-dione. Grades: ≥99% by HPLC. CAS No. 39156-67-7. Molecular formula: C29H39NO5. Mole weight: 481.60. | |
| Cytochalasin B | It is produced by the strain of Helminthosporium dematioideum, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytosine B has immunosuppressive effects. Synonyms: (7S,13E,16R,20R,21E)-7,20-Dihydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-6(12),13,21-triene-1,23-dione; (E,E)-(5R,9R,12aS,13S,15S,15aS,16S,18aS)-16-Benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-2H-Oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione; NSC 107658; Phomin. Grades: >99% by HPLC. CAS No. 14930-96-2. Molecular formula: C29H37NO5. Mole weight: 479.61. | |
| Cytochalasin C | It is produced by the strain of Metarrhizium anisopliae, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: 3-Benzyl-3,3a,6,6a,9,10,12,15-octahydro-6,12,15-trihydroxy-4,5,10,12-tetramethyl-1H-cycloundec[d]isoindole-1,11(2H)-dione 15-Acetate; (7S,13E,16S,18R,19E,21R)-21-(acetyloxy)-7,18-dihydroxy-16,18-dimethyl-10-phenyl-[11]Cytochalasa-5,13,19-triene-1,17-dione; [3S-(3R*, 3aS*, 6R*, 6aS*, 7E, 10R*, 12S*, 13E, 15S*, 15aS*)]-15-(Acetyloxy)-3, 3a, 6, 6a, 9, 10, 12, 15-octahydro-6, 12-dihydroxy-4, 5, 10, 12-tetramethyl-3-(phenylmethyl)-1H-Cycloundec[d]isoindole-1, 11(2H)-dione. Grades: >99% by HPLC. CAS No. 22144-76-9. Molecular formula: C30H37NO6. Mole weight: 507.62. | |
| Cytochalasin F | It is produced by the strain of Helminthosporium dematioideum, Coriolus vernicipes. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: (7S,13E,16R,20R,21E)-6,7-Epoxy-20-hydroxy-16-methyl-10-phenyl-24-oxa[14]cytochalasa-13,21-diene-1,23-dione; 24-Oxa(14)cytochalasa-13,21-diene-1,23-dione,6,7-epoxy-20-hydroxy-16-methyl-10-phenyl-, (7S,13E,16R,20R,21E)-. CAS No. 36084-18-1. Molecular formula: C29H37NO5. Mole weight: 479.61. | |
| Cytochalasin G | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. CAS No. 54874-57-6. Molecular formula: C29H34N2O4. Mole weight: 474.59. | |
| Cytochalasin K | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: 3H-Cyclotridec(d)oxireno(f)isoindole-8,11,12(13H)-trione, 7-(acetyloxy)-4,7,14,14a,15,15a,16a,16b-octahydro-4,6,15,15a-tetramethyl-14-(phenylmethyl)-, (1E, 4S, 5E, 7R, 9E, 11aR, 14S, 14aR, 15S, 15aR, 16aS, 16bR)-. CAS No. 79648-72-9. Molecular formula: C32H37NO6. Mole weight: 531.64. | |
| Cytochalasin L | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: 24-Oxa(14)cytochalasa-13,17,21-triene-1,20,23-trione, 19-(acetyloxy)-6,7-epoxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,17E,19R,21E)-; 3H-Oxacyclotetradecino(2,3-d)oxireno(f)isoindole-8,11,13(14H)-trione, 7-(acetyloxy)-4,7,15,15a,16,16a,17a,17b-octahydro-4,6,16,16a-tetramethyl-15-(phenylmethyl)-, (1E, 4S, 5E, 7R, 9E, 12aS, 15S, 15aS, 16S, 16aR, 17aS, 17bS)-. CAS No. 79637-87-9. Molecular formula: C32H37NO7. Mole weight: 547.64. | |
| Cytochalasin M | It is produced by the strain of Curvularia lunata, Drechslera dematioidea. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Synonyms: 24-Oxa(14)cytochalasa-13,17-diene-1,19,23-trione, 6,7-epoxy-20-hydroxy-16,18-dimethyl-10-phenyl-, (7S,13E,16S,17E,20S)-; 3H-Oxacyclotetradecino(2,3-d)oxireno(f)isoindole-7,11,13(4H,8H,14H)-trione,9,10,15,15a,16,16a,17a,17b-octahydro-8-hydroxy-4,6,16,16a-tetramethyl-15-(phenylmethyl)-, (4S-(1E, 4R*, 5E, 8R*, 12ar*, 15R*, 15ar*, 16R*, 16as*, 17ar*, 17br*))-. CAS No. 79648-73-0. Molecular formula: C30H37NO6. Mole weight: 507.62. | |
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