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It is produced by the strain of Pestalotia sp. AB 1942R-114. It has many biological activities, such as inhibiting cytokinesis reversibly, inhibiting megasophil endocytosis and exocytosis. Cytosine J has immunosuppressive effects. Synonyms: Deacetylcytochalasin H; Kodocytochalasin 2; Paspalin P II; [3S-(3R*, 3aS*, 4R*, 6R*, 6aS*, 7E, 10R*, 12S*, 13E, 15S*, 15aS*)]-2, 3, 3a, 4, 5, 6, 6a, 9, 10, 11, 12, 15-Dodecahydro-6, 12, 15-trihydroxy-4, 10, 12-trimethyl-5-methylene-3-(phenylmethyl)-1H-cycloundec[d]isoindol-1-one; (7S,13E,16S,18R,19E,21R)-7,18,21-Trihydroxy-16,18-dimethyl-10-phenyl-[[11]cytochalasa-6(12),13,19-trien-1-one. Grades: ≥ 95%. CAS No. 56144-22-0. Molecular formula: C28H37NO4. Mole weight: 451.60.
Cytochalasin J is one of a family of potent mycotoxins produced by a range of fungi. All members of the class exhibit profound effects on cytoskeletal proteins which give rise to pronounced morphogenic activity in animals and plants. Cytochalasin J is the deacetyl analogue of cytochalasin H and exhibits similar, though less potent, antibacterial, antifungal, nematocidal and antitumor activities. Group: Biochemicals. Alternative Names: Kodocytochalasin 2, Paspalin P11, Deacetylcytochalasin H, 17-Deoxo-zygosporin D. Grades: Highly Purified. CAS No. 56144-22-0. Pack Sizes: 1mg. US Biological Life Sciences.
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