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| Product | Description | |
|---|---|---|
| Cytostatin | Cytostatin is a potent and selective inhibitor of protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), but it doesn't have effect against PP1, PP2B, or PP5. Synonyms: 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-, (5S,6S)-; (5S,6S)-5,6-Dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-2H-pyran-2-one; 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrienyl]-5-methyl-, (5S,6S)-; (+)-Cytostatin; Antibiotic MJ 654NF4; NSC 675266. Grades: ≥75%. CAS No. 682329-63-1. Molecular formula: C21H33O7P. Mole weight: 428.46. |  |
| Cytostatin (5,6-Dihydro-6-(6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrienyl)-5-methyl-2H-pyran-2-one) | Potent and selective protein phosphatase 2A (PP2A) inhibitor. Cell adhesion inhibitor. Inhibits the adhesion of B16 melanoma cells to laminin and collagen type IV in a dose dependent manner but not to fibronectin. Antitumor agent. Antimetastatic. Apoptosis inducer. Group: Biochemicals. Grades: Purified. CAS No. 156856-30-3. Pack Sizes: 250ug. US Biological Life Sciences. |  Worldwide |
| Cytostatin sodium salt | Cytostatin is a potent and selective inhibitor of protein phosphatase 2A (PP2A; IC50 = 29 nM against the catalytic subunit), but it doesn't have effect against PP1, PP2B, or PP5. Synonyms: 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrien-1-yl]-5-methyl-, sodium salt (1:1), (5S,6S)-; 2H-Pyran-2-one, 5,6-dihydro-6-[(1S,4S,5S,6S,7Z,9Z,11E)-6-hydroxy-1,5-dimethyl-4-(phosphonooxy)-7,9,11-tridecatrienyl]-5-methyl-, monosodium salt, (5S,6S)-; (+)-Cytostatin sodium salt; NSC 675266 sodium salt. Grades: ≥75%. CAS No. 457070-06-3. Molecular formula: C21H32NaO7P. Mole weight: 450.44. | |
| Rubratoxin A | Rubratoxin A is a competitive inhibitor of protein phosphatase 2A (PP2A) with anticancer activity. It hardly inhibits any other phosphatases. Rubratoxin A showed higher suppression of tumor metastasis and reduction of the primary tumor volume than cytostatin in mouse experiments. Synonyms: BRN 1633008; HSDB 3532. Grades: ≥95%. CAS No. 22467-31-8. Molecular formula: C26H32O11. Mole weight: 520.5. | |
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