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| Product | Description | |
|---|---|---|
| Danoprevir | Danoprevir. Group: Biochemicals. Alternative Names: 4-Fluoro-1,3-dihydro-2H-isoindole-2-carboxylic Acid (2R, 6S, 13aS, 14aR, 16aS) -14a- [ [ (Cyclopropylsulfonyl) amino]carbonyl]-6- [ [ (1, 1-dimethylethoxy) carbonyl]amino]-1, 2, 3, 5, 6, 7, 8, 9, 10, 11, 13a, 14, 14a, 15, 16, 16a-hexadecahydro-5, 16-dioxocyclopropa [e]pyrrolo [1, 2-a] [1, 4]diazacyclopentadecin-2-yl Ester; EBP 521; ITMN 191; ITMN B; Intermune ITMN-191; R 05190591; R 7227. Grades: Highly Purified. CAS No. 850876-88-9. Pack Sizes: 2.5mg. Molecular Formula: C25H46FN5O9S, Molecular Weight: 731.83. US Biological Life Sciences. |  Worldwide |
| Danoprevir | Danoprevir (ITMN-191) is an orally active NS3/4A protease inhibitor for hepatitis C virus (HCV) with an IC 50 of 0.29 nM and is selective for NS3/4A over a panel of 53 proteases ( IC 50 higher than 10 μM). Danoprevir (ITMN-191) inhibits HCV genotypes 1a, 1b, 4, 5, and 6 ( IC 50 s=0.2-0.4 nM) as well as 2b and 3a ( IC 50 s=1.6, 3.5 nM) [1] [2]. Danoprevir is also a SARS-CoV 3CL pro inhibitor with an IC 50 of 0.05 μM [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ITMN-191; R7227; RO5190591; RG7227. CAS No. 850876-88-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10238. |  |
| Danoprevir | Danoprevir(ITMN-191;R7227; RO5190591;RG7227) is a peptidomimetic inhibitor of the NS3/4A protease of hepatitis C virus (HCV) with IC50 of 0.2-3.5 nM, inhibition effect for HCV genotypes 1A/1B/4/5/6 is ~10-fold higher than 2B/3A. Synonyms: RG7227; RG 7227; RG-7227; ITMN191; ITMN-191; ITMN 191; RO5190591; RO-5190591; RO 5190591. Grades: 0.98. CAS No. 850876-88-9. Molecular formula: C35H46FN5O9S. Mole weight: 731.837. |  |
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