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| Product | Description | |
|---|---|---|
| Dapagliflozin propanediol | Dapagliflozin propanediol is the salt of Dapagliflozin, which is a selective, orally active renal sodium-glucose cotransporter type 2 (SGLT2) inhibitor used for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: Dapagliflozin propanediol anhydrous; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol (1:1); Dapagliflozin S-propylene glycol; (2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol, (2S)-propane-1,2-diol (1:1). Grade: ≥95%. CAS No. 1971128-01-4. Molecular formula: C21H25ClO6.C3H8O2. Mole weight: 484.97. |  |
| Dapagliflozin propanediol hydrate | Dapagliflozin (2S)-1,2-propanediol, hydrate is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the treatment of type 2 diabetes mellitus (T2DM). It inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. Synonyms: Dapagliflozin (2S)-1,2-propanediol, hydrate; Dapagliflozin propylene glycol hydrate; D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol, hydrate (1:1:1); D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, compd. with (2S)-1,2-propanediol (1:1), monohydrate; (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-D-glucitol (S)-propane-1,2-diol (1:1) monohydrate; Dapagliflozin (S)-propylene glycol hydrate; Dapagliflozin propanediol monohydrate; Edistride; Farxiga; Forxiga; (2S,3R,4R,5S,6R)-2-[4-Chloro-3-(4-ethoxybenzyl)phenyl]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (S)-propane-1,2-diol (1:1) monohydrate. Grade: >98%. CAS No. 960404-48-2. Molecular formula: C24H35ClO9. Mole weight: 502.98. | |
| Dapagliflozin ((2S)-1,2-propanediol, hydrate) | Dapagliflozin ((2S)-1,2-propanediol, hydrate) is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin ((2S)-1,2-propanediol, hydrate), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine[1]. Dapagliflozin ((2S)-1,2-propanediol, hydrate) induces HIF1 expression and attenuates renal IR injury[2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-512148 (2S)-1,2-propanediol, hydrate. CAS No. 960404-48-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10450A. |  |
| Dapagliflozin Impurity 3 (S)-(+)-1,2-Propanediol Monohydrate | Dapagliflozin Impurity 3 (S)-(+)-1,2-Propanediol Monohydrate is an impurity of Dapagliflozin. Dapagliflozin is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2) in development for the treatment of type 2 diabetes mellitus (T2DM). Synonyms: 4-Dechloro-4-bromo Dapagliflozin (S)-(+)-1,2-Propanediol Monohydrate; Dapagliflozin 4-bromo Impurity (S)-(+)-1,2-Propanediol Monohydrate. Molecular formula: C21H25BrO6.C3H8O2.H2O. Mole weight: 547.43. | |
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