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| Product | Description | |
|---|---|---|
| Dasatinib monohydrate | Dasatinib (BMS-354825) monohydrate is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib monohydrate inhibits Bcr-Abl and Src with IC 50 s of <1.0 nM and 0.5 nM, respectively [1]. Dasatinib monohydrate also induces apoptosis and autophagy. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BMS-354825 monohydrate. CAS No. 863127-77-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-10181B. |  |
| Dasatinib Monohydrate | A pyrimidine and thiazole derived ANTINEOPLASTIC AGENT and PROTEIN KINASE INHIBITOR of BCR-ABL KINASE. It is used in the treatment of patients with CHRONIC MYELOID LEUKEMIA who are resistant or intolerant to IMATINIB. Alternative Names: Dasatinib monohydrate. Dasatinib hydrate. Dasatinib (monohydrate). BMS 35482503. CAS No. 863127-77-9. Product ID: API863127779. Molecular formula: C22H28ClN7O3S. Mole weight: 506. SMILES: CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO.O. Appearance: White or off-white powder. Category: Anti-Tumor APIs. |  |
| Dasatinib Monohydrate | Dasatinib Monohydrate is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. It is a COVID19-related research product. Group: Biochemicals. Alternative Names: N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide, monohydrate (9CI); BMS 35482503;Dasatinib hydrate. Grades: Highly Purified. CAS No. 863127-77-9. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C??H??ClN?O?S (H?O), Molecular Weight: 506.02. US Biological Life Sciences. |  Worldwide |
| Dasatinib Monohydrate | Dasatinib Monohydrate is a novel, potent and multi-targeted inhibitor that targets Abl, PDGFR, ephrin receptors, Src, c-Kit, and other Src-family kinases (LCK, HCK, FYN, and others). Uses: Antineoplastic agents. Synonyms: BMS-354825 Monohydrate; BMS 354825 Monohydrate; BMS354825 Monohydrate; N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide hydrate. Grade: >98%. CAS No. 863127-77-9. Molecular formula: C22H28ClN7O3S. Mole weight: 506.02. |  |
| Dasatinib | A multi-targeted kinase inhibitor, it is used, particularly as the monohydrate, for the treatment of chronic, accelerated, or myeloid or lymphoid blast phase chronic myeloid leukemia. Alternative Names: Sprycel BMS-354825 Dasatinib anhydrous. CAS No. 302962-49-8. Product ID: API302962498. Molecular formula: C22H26ClN7O2S. Mole weight: 488. EINECS: 801-607-0. SMILES: CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO. Appearance: White to Off-White Solid. Standard: Facility GMP. Category: Anti-Tumor APIs. | |
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