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| Product | Description | |
|---|---|---|
| Decernotinib | Decernotinib is a potent and selective JAK3 inhibitor. It has been shown to dose-dependently reduce proinflammatory responses in a rat collagen-induced arthritis model and a mouse model of oxazolone-induced delayed-type hypersensitivity. Synonyms: Adelatinib; VX-509; VRT-831509; (2R)-2-methyl-2-[[2-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-N-(2,2,2-trifluoroethyl)butanamide. Grade: >98%. CAS No. 944842-54-0. Molecular formula: C18H19F3N6O. Mole weight: 392.286. |  |
| Decernotinib | Decernotinib is a potent, orally active JAK3 inhibitor, with K i s of 2.5, 11, 13 and 11 nM for JAK3 , JAK1, JAK2, and TYK2, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VX-509; VRT-831509. CAS No. 944842-54-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12469. |  |
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