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| Product | Description | |
|---|---|---|
| Defactinib hydrochloride | Defactinib HCl is a potent FAK phosphorylation inhibitor, overcoming YB-1-mediated paclitaxel resistance by an AKT-dependent pathway. Synonyms: N-Methyl-4-((4-(((3-(methyl(methylsulfonyl)amino)pyrazin-2-yl)methyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide monohydrochloride; Defactinib hydrochloride; Defactinib HCl; VS6063; VS 6063; VS-6063; PF04554878; PF-04554878; PF 04554878; PF4554878; PF-4554878; PF4554878. Grades: >98%. CAS No. 1073160-26-5. Molecular formula: C20H22ClF3N8O3S. Mole weight: 546.95. |  |
| Defactinib hydrochloride | Defactinib hydrochloride (VS-6063 hydrochloride; PF 04554878 hydrochloride) is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VS-6063 hydrochloride; PF 04554878 hydrochloride. CAS No. 1073160-26-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12289A. |  |
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