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Deferoxamine, also known as desferrioxamine or DFO, is a medication used primarily for the treatment of iron overload in conditions such as thalassemia major and transfusional hemosiderosis. Deferoxamine is an iron-chelating agent, meaning it binds to excess iron in the body and forms a stable complex that is then excreted primarily through urine and feces. It binds to both ferric (Fe3+) and ferrous (Fe2+) ions, but its affinity for ferric iron is stronger. Deferoxamine can up-regulate HIF-1α level and induce apoptosis of cells. Deferoxamine is primarily used for the treatment of chronic iron overload due to repeated blood transfusions, such as in thalassemia major or sickle cell disease. It can also be used in cases of acute iron poisoning to help remove excess iron from the body. Synonyms: N-[5-[[4-[[5-(Acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N-(5-aminopentyl)-N-hydroxybutanediamide; 30-Amino-3,14,25-trihydroxy-3,9,14,20,25-pentaazatriacontane-2,10,13,21,24-pentaone; Deferoxamin; Deferoxamine B; Deferriferrioxamine B; Deferrioxamine; Deferrioxamine B; Desferan; Desferex; Desferin; Desferioxamine B; Desferoxime; Desferrin; Desferrioxamine; Desferrioxamine. Grade: ≥95%. CAS No. 70-51-9. Molecular formula: C25H48N6O8. Mole weight: 560.69.
Deferoxamine
Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19 [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Deferoxamine B; Deferriferrioxamine B; Deferrioxamine. CAS No. 70-51-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-B1625.
Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine mesylate upregulates HIF-1α levels with good antioxidant activity. Deferoxamine mesylate also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine mesylate can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19 [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Desferrioxamine B mesylate; DFOM. CAS No. 138-14-7. Pack Sizes: 20 mg; 100 mg; 500 mg. Product ID: HY-B0988.
Deferoxamine mesylate
Deferoxamine mesylate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: deferoxaminebmesylate;deferoxaminemesilate;deferoxaminemethanesulfonate;desferal;desferalmesylate;desferalmethanesulfonate;desferrioxaminebmesylate;desferrioxaminebmethanesulfonate. Product Category: Heterocyclic Organic Compound. Appearance: powder. CAS No. 138-14-7. Molecular formula: C26H52N6O11S. Mole weight: 656.79. Product ID: ACM138147. Alfa Chemistry ISO 9001:2015 Certified.
Deferoxamine mesylate
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Deferoxamine Mesylate - CAS 138-14-7
Parenteral iron chelating agent. Commonly used in therapy as a chelator of ferric iron in disorders of iron overload. Group: Fluorescence/luminescence spectroscopy.
Deferoxamine Mesylate (NSC 644468)
An iron chelator used for the treatment of acute iron intoxication and of chronic iron overload due to transfusion-dependent anemias. Has been shown to have anti-proliferative effects on vascular smooth muscle cells in vitro and in vivo and to arrest cells in the G1 phase. Induces apoptosis in HL-60 cells by chelating iron. In addition, it has been shown to have antioxidant properties and to protect cells against H?O?-induced damage. Group: Biochemicals. Alternative Names: N1- (5-aminopentyl) -N1-hydroxy-N4- [5- [ [4- [ [5- (acetylhydroxyamino) pentyl] amino] -1, 4-dioxobutyl] hydroxyamino] pentyl] butanediamide Methanesulfonate; N- [5- [3- [ (5-aminopentyl) hydroxycarbamoyl] propionamido] pentyl] -3- [ [5- (N-hydroxyacetamido) pentyl] carbamoyl] propionohydroxamic Acid Methanesulfonate; Ba 33112; DFOM; DFX mesylate; Deferoxamine B mesylate; Deferoxamine methanesulfonate; Deferrioxamine B methanesulfonate; Desferal mesylate; Desferrioxamine B mesylate; Desferrioxamine methanesulfonate; NSC 644468. Grades: Highly Purified. CAS No. 138-14-7. Pack Sizes: 1g, 5g, 10g. Molecular Formula: C??H??N?O?·CH?O?S, Molecular Weight: 656.79. US Biological Life Sciences.
Deferoxamine (mesylate) (Standard) is the analytical standard of Deferoxamine (mesylate). This product is intended for research and analytical applications. Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine mesylate upregulates HIF-1α levels with good antioxidant activity. Deferoxamine mesylate also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine mesylate can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19 [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 138-14-7. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0988R.
Desferioxamine mesylate
Deferoxamine mesylate is an iron chelator used in the treatment of acute iron poisoning and sickle cell diseases. It is also found to have some extent of antioxidant effects. Deferoxamine can up-regulate HIF-1α level and induce apoptosis of cells. Uses: Deferoxamine mesylate is an iron chelator that could be used in the treatment of acute iron poisoning, sickle cell diseases and it is also found to have some extent of antioxidant effects. Synonyms: Butanediamide, N4-[5-[[4-[[5-(acetylhydroxyamino)pentyl]amino]-1,4-dioxobutyl]hydroxyamino]pentyl]-N1-(5-aminopentyl)-N1-hydroxy-, methanesulfonate (1:1); Ba 33112; Deferoxamine B mesylate; Deferoxamine methanesulfonate; Deferrioxamine B methanesulfonate; Deferrioxamine methanesulfonate; Desferal; Desferal mesylate; Desferrioxamine B mesylate; Desferrioxamine B methanesulfonate; Desferrioxamine mesilate; Desferrioxamine mesylate; Desferrioxamine methanesulfonate; DFOM; DFX mesylate; NSC 644468. Grade: 95%. CAS No. 138-14-7. Molecular formula: C26H52N6O11S. Mole weight: 656.79.
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