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| Product | Description | |
|---|---|---|
| Delamanid | 25mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C25H25F3N4O5. CAS No. 681492-22-8. Prepack ID 90026659-25mg. Molecular Weight 534.48. See USA prepack pricing. |  |
| Delamanid | Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OPC-67683. CAS No. 681492-22-8. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10846. |  |
| Delamanid | Delamanid is used for the treatment of multi-drug-resistant tuberculosis. It functions by blocking the synthesis of mycolic acids in Mycobacterium tuberculosis, the organism which causes tuberculosis, thus destabilising its cell wall. Uses: The treatment of multi-drug-resistant tuberculosis. Synonyms: OPC-67683; OPC 67683; OPC67683; Deltyba; (2R)-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]piperidin-1-yl]phenoxy]methyl]-3H-imidazo[2,1-b][1,3]oxazole. Grades: ≥98%. CAS No. 681492-22-8. Molecular formula: C25H25F3N4O6. Mole weight: 534.492. |  |
| 1-[4-[ (Tetrahydro-2H-pyran-2-yl) oxy]phenyl]-4-[4- (trifluoromethoxy) phenoxy]piperidine | 1-[4-[ (Tetrahydro-2H-pyran-2-yl) oxy]phenyl]-4-[4- (trifluoromethoxy) phenoxy]piperidine is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 681482-80-4. Pack Sizes: 5mg, 25mg. Molecular Formula: C23H26F3NO4. US Biological Life Sciences. |  Worldwide |
| 2-Chloro-1-[[(2R)-2-methyloxiranyl]methyl]-4-nitro-1H-imidazole | 2-Chloro-1-[[(2R)-2-methyloxiranyl]methyl]-4-nitro-1H-imidazole is an intermediate in the synthesis of Delamanid, a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 681490-93-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C7H8ClN3O3. US Biological Life Sciences. | Worldwide |
| (2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol | (2R)-3-(2-Chloro-4-nitro-1H-imidazol-1-yl)-2-methyl-1,2-propanediol is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis. Group: Biochemicals. Grades: Highly Purified. CAS No. 681490-91-5. Pack Sizes: 10mg, 25mg. Molecular Formula: C7H10ClN3O4. US Biological Life Sciences. | Worldwide |
| TBA-354 | TBA-354 is narrow spectrum and bactericidal in vitro against replicating and nonreplicating Mycobacterium tuberculosis, with potency similar to that of delamanid and greater than that of PA-824. TBA-354 maintains activity against Mycobacterium tuberculosis H37Rv isogenic monoresistant strains and clinical drug-sensitive and drug-resistant isolates. TBA-354 is 5 to 10 times more potent than PA-824, but selected mutants are cross-resistant to PA-824 and delamanid. TBA-354 is 2 to 4 times more potent than PA-824 when combined with bedaquiline, and when administered at a dose equivalent to that of PA-824, TBA-354 demonstrated superior sterilizing efficacy. TBA-354 has high bioavailability and a long elimination half-life. In vitro studies suggest a low risk of drug-drug interactions. Low-dose aerosol infection models of acute and chronic murine tuberculosis reveal time- and dose-dependent in vivo bactericidal activity that is at least as potent as that of delamanid and more potent than that of PA-824. Synonyms: TBA-354, TBA 354, TBA354, SN31354, SN-31354, SN 31354. Grades: >98%. CAS No. 1257426-19-9. Molecular formula: C19H15F3N4O5. Mole weight: 436.34. | |
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