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Demecolcine is a potent mitotic inhibitor with an IC 50 value of 2.4 μM for inhibition of tubulin polymerization. Colcemid (Demecolcine) can interact with tubulin dimers to induce anti-mitotic action and inhibit microtubule growth. Colcemid (Demecolcine) can be used for inflammatory disorders and cancer research [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 477-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N0282.
Demecolcine-[d3]
Demecolcine-[d3] is the labelled analogue of Demecolcine. Demecolcine is an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. It stimulates the intrinsic GTPase activity of tubulin. It also induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway. Synonyms: Demecolcine D3; (7S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methylamino)-benzo[a]heptalen-9(5H)-one-d3; Deacetylmethylcolchicine-d3; Colchamin-d3; NSC 3096-d3; Omain-d3; Omaine-d3; N-Desacetyl-N-methylcolchicine-d3; Colcemid-d3. Grade: >95%. CAS No. 1217668-72-8. Molecular formula: C21H22D3NO5. Mole weight: 374.45.
An isotopically labeled an. Group: Biochemicals. Alternative Names: N-Desacetyl-N-methylcolchicine-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Demecolcine-[d6]
Demecolcine-[d6] is the labelled analogue of Demecolcine. Demecolcine is an antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. It stimulates the intrinsic GTPase activity of tubulin. It also induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway. Synonyms: Demecolcine D6; (7S)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-(methylamino)-benzo[a]heptalen-9(5H)-one-d6; Deacetylmethylcolchicine-d6; Colchamin-d6; NSC 3096-d6; Omain-d6; Omaine-d6; N-Desacetyl-N-methylcolchicine-d6; Colcemid-d6. Grade: >95%. CAS No. 1217602-04-4. Molecular formula: C21H19D6NO5. Mole weight: 377.46.
An isotopically labeled an. Group: Biochemicals. Alternative Names: N-Desacetyl-N-methylcolchicine-d6. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Demecolcine Hydrogen Bromide Salt (N-Desacetyl-N-methylcolchicine, Hydrogen Bromide Salt)
Demecolcine Hydrogen Bromide Salt (N-Desacetyl-N-methylcolchicine, Hydrogen Bromide Salt). Group: Biochemicals. Alternative Names: N-Desacetyl-N-methylcolchicine, Hydrogen Bromide Salt. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
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Demecolcine (N-Desacetyl-N-methylcolchicine)
Demecolcine (N-Desacetyl-N-methylcolchicine). Group: Biochemicals. Alternative Names: N-Desacetyl-N-methylcolchicine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Demecolcine solution
10 ?g/mL in HBSS, ACF Qualified. Group: Fluorescence/luminescence spectroscopy.
N-(2-Mercaptoethyl) Demecolcine
N-(2-Mercaptoethyl) Demecolcine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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Colcemide
Colcemide. Group: Biochemicals. Alternative Names: N-Deacetyl-N-methylcolchicine ; Demecolcine. Grades: Highly Purified. CAS No. 477-30-5. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C21H25NO5. US Biological Life Sciences.
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Demecolceine
Demecolceine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-DESACETYL-N-METHYLCOLCHICEINE;DEMECOLCEINE. Product Category: Heterocyclic Organic Compound. Appearance: Yellow Solid. CAS No. 518-11-6. Molecular formula: C20H23NO5. Mole weight: 357.4. Purity: 0.96. IUPACName: (7S)-10-hydroxy-1,2,3-trimethoxy-7-(methylamino)-6,7-dihydro-5H-benzo[a]heptalen-9-one. Canonical SMILES: CNC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)O)OC)OC)OC. Density: 1.27g/cm³. Product ID: ACM518116. Alfa Chemistry ISO 9001:2015 Certified. Categories: Demecolcine.
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