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| Product | Description | |
|---|---|---|
| 2-Amino-2'-deoxy-N2, N6-bis (diisobutylamino methyl idene) -5'-O-DMT-adenosine 3'-CE phosphoramidite | 2-Amino-2'-deoxy-N2, N6-bis (diisobutylamino methyl idene) -5'-O-DMT-adenosine 3'-CE phosphoramidite. Group: Biochemicals. Alternative Names: 5'- (4, 4'-Dimethoxytrityl) -N2, N6-bis (diisobutylamino methyl idene) - 2,6-diamino-2'-deoxypurine riboside 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. |  Worldwide |
| 2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite | 2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite stands as an indispensable entity in spurring nucleic acid synthesis. As an agent that cultivates the establishment of phosphodiester bonds in solid-phase synthesis of DNA and RNA fragments, it provides fundamental advancements to the probing and treatment of genetic maladies and cancerous conditions. When utilized to its fullest capacity, 2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-adenosine 3'-CE phosphoramidite galvanizes the synthesis of oligonucleotides and probes, profoundly accelerating treatment and diagnosis of ailments. Synonyms: 5'-(4,4'-Dimethoxytrityl)-N2,N6-bis(diisobutylaminomethylidene)-2,6-diamino-2'-deoxypurine riboside 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 2-Amino-2'-deoxy-N2,N6-bis(diisobutylaminomethylidene)-5'-O-DMT-D-adenosine 3'-CE phosphoramidite; 2-Amino-dA-CE phosphoramidite. Molecular formula: C58H83N10O6P. Mole weight: 1047.32. |  |
| 2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite | 2'-Deoxy-5'-O-DMT-N6-Fmoc-adenosine 3'CE-phosphoramidite, a highly coveted resource in the realm of biomedical research, serves as a catalyst for generating customized nucleic acid structures. Delving into unexplored terrains, this versatile entity facilitates the infusion of N6-Fmoc-adenosine adaptations into oligonucleotides, enabling precise exploration of modified nucleic acids and their intricate interplay with designated proteins or enzymes. CAS No. 109420-86-2. | |
| 2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite | 2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine 3'-CE phosphoramidite is a crucial component used in the biomedical industry for synthesizing oligonucleotides. This phosphoramidite derivative aids in the introduction of 2'-Deoxy-5'-O-DMT-N6-methyl-8-oxoadenosine modifications into nucleic acids during solid-phase DNA synthesis. These customized nucleic acid sequences find application in various research fields, including medicinal chemistry, genetic engineering, and drug discovery, enabling the development of targeted therapies for specific diseases. Synonyms: 2'-Deoxy-5'-O-DMT-N6-methyl-8-oxo-D-adenosine 3'-CE phosphoramidite; 5'-O-DMT-N6-methyl-8-oxo-2'-deoxyadenosine 3'-CE phosphoroamidite. Molecular formula: C41H50N7O7P. Mole weight: 767.85. | |
| 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-Me phosphoramidite | 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-Me phosphoramidite, a highly regarded biochemical agent, has garnered considerable attention in the realm of biomedicine research. This extraordinary compound serves as an instrumental tool for facilitating DNA synthesis and modification, offering unprecedented opportunities for investigating intricate cellular mechanisms and disease etiology. By employing its unique modifications, researchers can delve into a myriad of applications, encompassing the development of precision drug delivery systems and the conception of revolutionary gene-based therapies targeting a wide spectrum of ailments, such as cancer and hereditary disorders. Synonyms: Pac-dA-Me Phosphoramidite; 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyl-D-adenosine 3'-Me phosphoramidite; 5'-O-DMT-N6-phenoxyacetyl-2'-deoxyadenosine 3'-Me phosphoramidite. Molecular formula: C46H53N6O8P. Mole weight: 848.94. | |
| 2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite | 2'-Deoxy-N6-DMF-5'-O-MMT-adenosine 3'-CE phosphoramidite: A versatile compound extensively utilized in the biomedical industry for synthesizing modified RNA sequences. It serves as a building block in the development of nucleic acid-based therapeutics targeting various diseases, including cancers. Its unique structure enables precise modification and delivery of therapeutic RNA molecules, enhancing their efficacy and specificity in disease treatment. Synonyms: 2'-Deoxy-N4-DMF-5'-O-MMT-D-adenosine 3'-CE phosphoramidite; N4-DMF-5'-O-MMT-2'-deoxyadenosine 3'-CE phosphoramidite. Molecular formula: C42H51N8O5P. Mole weight: 778.90. | |
| 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(methyl-N,N-diisopropyl)phosphoramidite | dA(Bz)-3'-Methoxy Phosphoramidite is a modified phosphoramidite designed for specialized oligonucleotide synthesis. The adenine base is protected with a benzoyl (Bz) group at the N6 position to prevent side reactions during synthesis. At the 3' position, the methoxy group replaces the standard hydroxyl group, providing unique structural properties and increased chemical stability to the oligonucleotide. The phosphoramidite functionality ensures efficient incorporation into oligonucleotide chains via automated synthesis. This modification is particularly useful in applications requiring oligonucleotides with altered backbone properties, improved hybridization characteristics, or enhanced resistance to enzymatic degradation, such as in therapeutic nucleic acids and molecular biology studies. Synonyms: dA(Bz)-3'-Methoxy Phosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[methyl bis(1-methylethyl)phosphoramidite]; N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-Me phosphonamidite; (2R,3S,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl methyl diisopropylphosphoramidite; 2'-Deoxy Adenosine (n-Bz) methyl phosphoramidite; DNA A(Bz) OMe-amidite; dA(Bz) OMe-amidite. Grade: ≥98%. CAS No. 84416-82-0. Molecular formula: C45H51N6O7P. Mole weight: 818.90. | |
| 5'-O-Benzyl-2'-deoxy-N6-DMF-adenosine 3'-CE phosphoramidite | 5'-O-Benzyl-2'-deoxy-N6-DMF-adenosine 3'-CE phosphoramidite, a pivotal component within the biomedical realm, proves indispensable for the fabrication of altered oligonucleotides. Facilitating the incorporation of the 5'-O-Benzyl-2'-deoxy-N6-DMF-adenosine 3'-CE modification during the synthesis of DNA or RNA, this derivative empowers scientists in their pursuit of investigating and manipulating nucleic acid architectures germane to afflictions encompassing malignancies, hereditary irregularities, and viral onslaughts. Synonyms: 5'-O-Benzyl-2'-deoxy-N6-DMF-D-adenosine 3'-CE phosphoramidite; 5'-O-Benzyl-N6-DMF-2'-deoxyadenosine 3'-CE phosphoramidite. Molecular formula: C29H41N8O4P. Mole weight: 596.68. | |
| 5'-O-DMT-N6-Acetyl-2'-deoxyadenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-Acetyl-2'-deoxyadenosine 3'-CE phosphoramidite is a key component for the synthesis of modified oligonucleotides, which have applications in gene therapy and antiviral drug development. This phosphoramidite can be used to introduce an N6-acetyldeoxyadenosine modification to oligonucleotide strands, which has been shown to enhance their cellular uptake and improve their stability towards nucleases. It is also useful for generating oligonucleotides with 3'-CE modifications, which can improve their binding and selectivity towards complementary RNA targets. Synonyms: Adenosine N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N-Acetyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxyadenosine. Grade: ≥98% by HPLC. CAS No. 1027734-01-5. Molecular formula: C42H50N7O7P. Mole weight: 795.86. | |
| 5'-O-DMT-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-Benzoyl-2'-deoxyadenosine 3'-CE phosphoramidite, an indispensable biomolecular tool, profoundly impacts the dynamic biomedical sphere. Its paramount significance lies in its pivotal role as a reagent for nucleoside or oligonucleotide synthesis, revolutionizing the study of DNA-protein interactions, gene expression, and research in molecular biology. Synonyms: N6-Benzoyl-5'-O-DMT-2'-deoxyadenosine 3'-CE phosphoramidite; dA(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-adenosine 3'-[2-cyanoethyl N,?N-Bis(1-methylethyl)?phosphoramidite]; DMT-dA(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grade: ≥98% by HPLC. CAS No. 98796-53-3. Molecular formula: C47H52N7O7P. Mole weight: 857.93. | |
| 5'-O-DMT-N6-methyl-2'-deoxyadenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-methyl-2'-deoxyadenosine 3'-CE phosphoramidite is a pivotal entity harnessed within the realm of biomedical industry, manifesting its indispensability within nucleic acid research and development. Synonyms: 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-methyl-Adenosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 2'-Deoxy-5'-O-DMT-N6-methyladenosine 3'-CE phosphoramidite; N6-Methyl-dA phosphoramidite. Grade: ≥98% by HPLC. CAS No. 105931-58-6. Molecular formula: C41H50N7O6P. Mole weight: 767.85. | |
| 5'-O-DMT-N6-Phenoxyacetyl-2'-deoxyadenosine 3'-CE phosphoramidite | 5'-O-DMT-N6-Phenoxyacetyl-2'-deoxyadenosine 3'-CE phosphoramidite is a crucial recompound in the dynamic biomedical field, exhibiting unparalleled versatility in application in synthesizing sophisticated modified oligonucleotides. Synonyms: 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-CE phosphoramidite; DMT-dA(tac) Phosphoramidite; N-(Phenoxyacetyl)-3'-O-[2-cyanoethoxy(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine; 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-(phenoxyacetyl)-adenosine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: 95%. CAS No. 110543-74-3. Molecular formula: C48H54N7O8P. Mole weight: 887.98. | |
| 8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite | 8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. CAS No. 211676-21-0. Pack Sizes: 250mg. Molecular Formula: C46H59N10O6P. US Biological Life Sciences. | Worldwide |
| 8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite | 8-Amino-2'-deoxy-N6,N8-di-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is a vital component used in the research and development of oligonucleotides for drug discovery. It offers efficient coupling to ensure accurate incorporation of adenosine nucleotides during the solid-phase research and development process. Synonyms: 5'-Dimethoxytrityl-N6,N8-bis(dimethylaminomethylidine)-8-amino-2'-deoxyAdenosine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 8-Amino-dA-CE Phosphoramidite; 8-Amino-2'-deoxy-D-adenosine 3'-CE phosphoramidite. CAS No. 211676-21-0. Molecular formula: C46H59N10O6P. Mole weight: 879.01. | |
| 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite | 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite | 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-adenosine 3'-CE phosphoramidite is an imperative compound, serving as an indispensable phosphorylation recompound engendering the amalgamation of oligonucleotides. Its pervasive utilization in the research of pharmacological exploration, primarily within the domain of nucleotide-based therapeutics spanning antisense oligonucleotides and siRNA. Synonyms: 8-Bromo-2'-deoxy-N6-DMF-5'-O-DMT-D-adenosine 3'-CE phosphoramidite; 8-Bromo-N6-DMF-5'-O-DMT-2'-deoxyadenosine 3'-CE phosphoramidite. Molecular formula: C43H52BrN8O6P. Mole weight: 887.82. | |
| Adenosine, 3'-?deoxy-?2'-?O-?[(1,?1-?dimethylethyl)?dimethylsilyl]?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?N-?(2-?phenoxyacetyl)?-?2-?[(2-?phenoxyacetyl)?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine, 3'-deoxy-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(2-phenoxyacetyl)-2-[(2-phenoxyacetyl)amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], a chemical compound highly employed as a reagent in oligonucleotide synthesis for biomedical research, as well as in the development of pharmacological interventions aimed at treating several cancers and viral infections, amongst them hepatitis B. Synonyms: Adenosine, 3'-deoxy-2'-O-[(1,1-dimethylethyl)dimethylsilyl]-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-N-(phenoxyacetyl)-2-[(phenoxyacetyl)amino]-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI). CAS No. 256485-55-9. Molecular formula: C61H74N9O9PSi. Mole weight: 1136.35. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?2'-?O-?(1,?1-?difluoro-?2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine N-benzoyl-3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a cutting-edge and highly effective modified nucleoside utilized in advanced biomedical research. With a distinctive and intricate chemical arrangement, it possesses unparalleled potential in gene therapies and drug delivery systems. This nucleoside has shown promising outcomes in the treatment and study of various genetic disorders and diseases, including cancer. Its exceptional stability and efficiency are beneficial in advancing research in these fields. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-(1,1-difluoro-2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-70-0. Molecular formula: C49H55F2N8O7P. Mole weight: 936.98. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?2'-?O-?(2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine, N-benzoyl-3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a potent phosphoramidite recompound widely employed for the research of modified oligonucleotides, particularly in the development of nucleotide-based drugs targeting specific diseases such as cancer, viral infections and genetic disorders. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-(2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299277-93-1. Molecular formula: C49H57N8O7P. Mole weight: 901. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?2'-?O-?ethyl-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine, N-benzoyl-3'-deoxy-2'-O-ethyl-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an imperative compound, finding extensive application for oligonucleotide drugs research. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-ethoxy-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299278-74-1. Molecular formula: C48H55N8O6P. Mole weight: 870.97. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?2'-?O-?2-?propen-?1-?yl-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Adenosine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an exceptional compound used in the research of formidable malignancies, such as lymphoma and leukemia. Its utilization in the pursuit of innovative antiviral therapeutics that specifically target RNA viruses denotes its indispensable role. Synonyms: ((2S,3R,4R,5R)-4-(allyloxy)-5-(6-benzamido-9H-purin-9-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299282-94-1. Molecular formula: C49H55N8O6P. Mole weight: 882.98. | |
| Adenosine, N-?benzoyl-?3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?2'-?O-?methyl-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Adenosine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-methyl-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a complex chemical entity employed in the synthesis of oligonucleotides targeting viral infections and various cancers. The versatility of this remarkable molecule extends beyond biomedical research and treatment; it has the potential to alter genetic sequences, thereby opening new therapeutic avenues for myriad hitherto enigmatic human ailments. Its designation as a universally valuable synthetic building block in both academic and clinical milieus underscores its indispensability in biomedicine. Synonyms: ((2S,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-4-methoxy-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 329773-22-0. Molecular formula: C47H53N8O6P. Mole weight: 856.95. | |
| N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite | N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite. Group: Biochemicals. Alternative Names: Ac-dC-CE Phosphoramidite. Grades: Highly Purified. Pack Sizes: 1g, 2g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine 5'-CE phosphoramidite | N6-Benzoyl-2'-deoxy-3'-O-DMT-adenosine 5'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine 3'-CE phosphoramidite | N6-Benzoyl-2'-deoxy-5'-O-DMT-a-adenosine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. | Worldwide |
| N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite | N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. CAS No. 98796-53-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C47H52N7O7P. US Biological Life Sciences. | Worldwide |
| 4-Amino-2,6-dimethyl-8-(2'-deoxy-β-D-ribofuranosyl)-7(8H)-pteridone | A highly fluorescent adenosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3',5'-phosphodiester linkage using an automated DNA synthesizer. Uses: A highly fluorescent adenosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3',5'-phosphodiester linkage using an automated dna synthesizer. Synonyms: 4-Amino-8-(2-deoxy-β-D-erythro-pentofuranosyl)-2,6-dimethyl-7(8H)pteridinone; DMAP. CAS No. 195442-56-9. Molecular formula: C13H17N5O4. Mole weight: 307.31. | |
| 4-Amino-6-methyl-8-(2-deoxy-β-D-ribofuranosyl)-7(8H)-pteridone | A highly fluorescent adenosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3',5'-phosphodiester linkage using an automated DNA synthesizer. Uses: A highly fluorescent adenosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3',5'-phosphodiester linkage using an automated dna synthesizer. Synonyms: 4-Amino-8-(2-deoxy-β-D-erythro-pentofuranosyl)-6-methyl-7(8H)-pteridinone; 6MAP. Grade: 95%. CAS No. 195442-55-8. Molecular formula: C12H15N5O4. Mole weight: 293.28. | |
| 5'-O-DMT-N1-Methy-N6-Chloroacetyl-2'-dA 3'-CE Phosphoramidite | 5'-O-DMT-N1-Methyl-N6-Chloroacetyl-2'-dA 3'-CE Phosphoramidite is a modified phosphoramidite used in oligonucleotide synthesis. This compound features a 2'-deoxyadenosine (dA) base substituted with an N1-methyl group and an N6-chloroacetyl protecting group, while the 5'-hydroxyl group is protected by a dimethoxytrityl (DMT) group, and the sugar moiety is functionalized with a 3'-cyanoethyl (CE) phosphoramidite group. These modifications enhance the stability and functionality of synthetic oligonucleotides, allowing for precise incorporation into DNA strands during automated synthesis. It is particularly useful in applications requiring site-specific methylation or alkylation for studying DNA-protein interactions or designing therapeutic nucleic acids. Synonyms: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-(chloroacetyl)-1-methyl-2'-deoxy-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; 2'-Deoxy-5'-O-DMT-N1-methy-N6-Chloroacetyladenosine 3'-CE phosphoramidite; N1-Methy-N6-Chloroacetyl-5'-O-DMT-2'-O-deoxyadenosine 3'-CE phosphoramidite. Grade: ≥98%. Molecular formula: C43H51ClN7O7P. Mole weight: 844.35. | |
| 7-TFA-ap-7-Deaza-2'-dA(Bz) Phosphoramidite | 7-TFA-ap-7-Deaza-2'-dA(Bz) Phosphoramidite is a modified phosphoramidite where the adenine base is substituted with a 7-deaza analog, functionalized with a trifluoroacetyl (TFA) protecting group on the 7-position. The exocyclic amine at the 6-position is protected with a benzoyl (Bz) group, while the sugar moiety includes a 3'-cyanoethyl (CE) phosphoramidite group for integration into automated DNA synthesis. This modification reduces base-pairing disruption and enhances chemical stability, making it valuable for synthesizing oligonucleotides used in structural studies, therapeutic applications, or creating DNA with altered recognition properties for studying DNA-protein or DNA-drug interactions. Synonyms: 7-TFA-ap-7-Deaza-N6-Bz-5'-O-DMTr-2'-deoxy-adenosine 3'-CED phosphoramidite; DMTr-7-TFA-ap-7-Deaza-dA(Bz)-3'-CE-Phosphoramidite; 7-TFA-ap-7-Deaza-2'-deoxy-A(Bz) phosphoramidite. Grade: ≥97%. Molecular formula: C53H54F3N6O8P. Mole weight: 991.02. | |
| AdemA-GalNAc Phosphoramidite | AdemA-GalNAc Phosphoramidite is a specialized phosphoramidite reagent used for the synthesis of oligonucleotides with liver-targeting capabilities. It combines adenine and GalNAc (N-Acetylgalactosamine) moieties to facilitate targeted delivery to hepatocytes via the asialoglycoprotein receptor (ASGPR). This reagent enhances the efficiency of oligonucleotide uptake in liver cells. Synonyms: Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-[[2-[2-[[1-oxo-5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]pentyl]amino]ethoxy]ethoxy]methyl]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; (2R,3R,4R,5R,6R)-5-Acetamido-2-(acetoxymethyl)-6-((5-((2-(2-((((2R,3R,4R,5R)-2-(6-benzamido-9H-purin-9-yl)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(((2-cyanoethoxy)(diisopropylamino)phosphaneyl)oxy)tetrahydrofuran-3-yl)oxy)methoxy)ethoxy)ethyl)amino)-5-oxopentyl)oxy)tetrahydro-2H-pyran-3,4-diyl diacetate; GalNAc Similar. Grade: ≥95%. CAS No. 1953147-02-8. Molecular formula: C71H90N9O20P. Mole weight: 1420.50. | |
| Amino-Modifier C6 dA | Amino-Modifier C6 dA is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dA can replace the dA residue to functionalize the target oligonucleotide. Synonyms: 5'-Dimethoxytrityl-N6-benzoyl-N8-[6-(trifluoroacetylamino)-hex-1-yl]-8-amino-2'-deoxyadenosine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-8-[[6-[(2,2,2-trifluoroacetyl)amino]hexyl]amino]-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-DMTr-8-C6-linker-TFA-2'-deoxy-3'-O-CEP-adenosine; Amino Modifier C6-dA CE-Phosphoramidite. Grade: ≥95%. CAS No. 1301170-09-1. Molecular formula: C55H65F3N9O8P. Mole weight: 1068.14. | |
| dA(Bz)-3'-PS Phosphoramidite | dA(Bz)-3'-PS Phosphoramidite is a deoxyadenosine-derived phosphoramidite designed for oligonucleotide synthesis with a 3'-phosphorothioate (PS) linkage. In this modification, a non-bridging oxygen atom in the phosphate backbone is replaced by a sulfur atom, significantly improving nuclease resistance and biological stability of the oligonucleotides. The adenine base is protected with a benzoyl (Bz) group at the N6 position to prevent side reactions during synthesis while maintaining proper base-pairing properties. This phosphoramidite is particularly valuable in therapeutic oligonucleotide development, such as antisense oligonucleotides and siRNA, where enhanced stability, enzymatic resistance, and prolonged biological activity are critical for efficacy. Synonyms: 5'-DMT-dA(Bz)-3'-PS-Phosphoramidite; dA(Bz) ThioPhosphamidite; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; S-(2-(((((2R,3S,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl)oxy)(pyrrolidin-1-yl)phosphaneyl)thio)ethyl) benzothioate. Grade: ≥90%. CAS No. 178272-29-2. Molecular formula: C51H51N6O7PS2. Mole weight: 955.09. | |
| dA(Bz)-PACE Phosphoramidite | dA-PACE Phosphoramidite is a crucial reagent utilized in the development of oligonucleotide therapeutics for treating various genetic disorders such as cystic fibrosis and Huntington's disease. The unique PACE (phosphoramidite conjugated to aminohexylCE) modification improves the pharmacokinetic properties of the resulting oligonucleotide drugs, allowing for enhanced cellular uptake and longer half-life in the body. Synonyms: dA-PACE Phosphoramidite; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyAdenosine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate; Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; DNA A(Bz) PACE amidite. Grade: ≥95%. CAS No. 411234-24-7. Molecular formula: C51H58N7O8P. Mole weight: 928.02. | |
| dA(PAc)-3'-Methoxy Phosphoramidite | dA(PAc)-3'-Methoxy Phosphoramidite is a modified phosphoramidite designed for oligonucleotide synthesis. The adenine base is protected with a phenoxyacetyl (PAc) group at the N6 position, providing stability and preventing undesired side reactions during synthesis. The 3'-hydroxyl group is substituted with a methoxy group, enhancing the chemical stability and altering the structural properties of the resulting oligonucleotides. The phosphoramidite functionality at the 3' position ensures efficient coupling during automated oligonucleotide synthesis. This modification is particularly useful in applications requiring oligonucleotides with increased stability and resistance to enzymatic degradation, such as in therapeutic nucleic acids, antisense technologies, and advanced molecular biology research. Synonyms: DMT-dA(PAc)-3'-Methoxy Phosphoramidite; 5'-O-DMTr-2'-deoxy-A(PAc)-3'-Methoxy-phosphoramidite; N6-Phenoxyacetyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-adenosine-3'-Methoxy-phosphoramidite; dA(PAc) OMe-amidite. Grade: ≥95%. Molecular formula: C46H53N6O8P. Mole weight: 848.94. | |
| (N6-Benzoyl)-5'-O-[(N,N-diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine | (N6-Benzoyl)-5'-O-[(N,N-diisopropylamino)-(2-cyanoethoxy)phosphinyl]-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine is a modified phosphoramidite used in oligonucleotide synthesis. This compound includes protective groups such as dimethoxytrityl (DMT), benzoyl (Bz), and cyanoethyl (CE). These protective groups play a crucial role in the synthesis process, ensuring correct assembly and sequence synthesis of nucleotides, particularly in reverse synthesis (from the 5' to 3' end). Synonyms: Adenosine, N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; Adenosine, N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N4-benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-5'-cyanoethyl Phosphoramidite; DMT-dA(Bz)-5'-CE Reverse Phosphoramidite; 3'-DMT-dA(Bz)-CE Reverse; 3'-O-DMTr-dA(Bz)-5'-CE-Phosphoramidite; DMT-dA(Bz)-CE Inverted Phosphoramidite; N6-benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine-5'-cyanoethyl Phosphoramidite. Grade: 95%. CAS No. 140712-82-9. Molecular formula: C47H52N7O7P. Mole weight: 857.93. | |
| 4-Amino-2,6-dimethyl-8-(2-deoxy-b-D-ribofuranosyl)-7(8H)-pteridone (DMAP) | A highly fluorescent adenosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3,5-phosphodiester linkage using an automated DNA synthesizer. Group: Biochemicals. Alternative Names: DMAP. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 4-Amino-6-methyl-8-(2-deoxy-b-D-ribofuranosyl)-7(8H)-pteridone (6MAP) | A highly fluorescent adenosine analogue, which in a dimethoxytrityl, phosphoramidite protected form, can be site-specifically inserted into oligonucleotides through a 3,5-phosphodiester linkage using an automated DNA synthesizer. Group: Biochemicals. Alternative Names: 6MAP. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
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