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| Product | Description | |
|---|---|---|
| 2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite | 2,3-Anhydro-N4-benzoyl-2-deoxycytidine 5-CE phosphoramidite, a highly essential oligonucleotide synthesis component utilized within the biomedical industry, has become tremendously emphasized, due to its diverse and efficient reactivity. Its notable characteristics are highly appreciated in scientific research, while its wide application, ranging from cancer treatment to viral infection mitigation, continues to garner the utmost respect. Synonyms: 2,3'-Anhydro-N4-benzyl-2'-deoxy-D-cytidine 5'-CE phosphoramidite. Molecular formula: C25H32N5O5P. Mole weight: 513.54. |  |
| 2'-Deoxy-5'-O-DMT-N4-(hexyloxylevulinyl)-5-methylcytidine 3'-CE phosphoramidite | 2'-Deoxy-5'-O-DMT-N4-(hexyloxylevulinyl)-5-methylcytidine 3'-CE phosphoramidite - a versatile reagent imperative for the synthesis of modified oligonucleotides and crucial for the field of biomedical research. Its significance is profound in understanding the association between epigenetic modifications, gene expression, and the progression of diseases, including cancer. The phosphoramidite empowers the smooth incorporation of modified cytidine residues into oligonucleotides, enabling the exploration of their impact on the biological system. Synonyms: 2'-Deoxy-5'-O-DMT-N4-(hexyloxylevulinyl)-5-methyl-D-cytidine 3'-CE-phosphoramidite; 5'-O-DMT-N4-(hexyloxylevulinyl)-5-methyl-2'deoxycytidine 3'-CE-phosphoramidite. Molecular formula: C51H68N5O10P. Mole weight: 942.11. | |
| 2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite | 2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite. Group: Biochemicals. Alternative Names: 2'-Deoxy-N4-DMF-5'-O-DMT-pseudoiso-D-cytidine 3'-CE phosphoramidite; N4-DMF-5'-O-DMT-2'-deoxypseudoisocytidine 3'-CE phosphoramidite. Grades: Highly Purified. CAS No. 307314-31-4. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C42H53N6O7P, Molecular Weight: 784.88. US Biological Life Sciences. |  Worldwide |
| 2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite | 2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite is an essential phosphoramidite derivative for oligonucleotide research and development, is extensively employed for advancing biomedical research and drug development. Its primary role lies in the modification of nucleic acids, empowering investigations on DNA and RNA structures, interactions, and functions. Synonyms: 2'-Deoxy-N4-DMF-5'-O-DMT-pseudoiso-D-cytidine 3'-CE phosphoramidite; N4-DMF-5'-O-DMT-2'-deoxypseudoisocytidine 3'-CE phosphoramidite. Grade: 95%. CAS No. 307314-31-4. Molecular formula: C42H53N6O7P. Mole weight: 784.88. | |
| 5'-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-(methyl-N,N-diisopropyl)phosphoramidite | 5'-Dimethoxytrityl-N4-benzoyl-2'-deoxycytidine-3'-(methyl-N,N-diisopropyl)phosphoramidite is a protected phosphoramidite derivative used in oligonucleotide synthesis. The cytosine base is protected at the N4 position with a benzoyl (Bz) group to prevent side reactions during chemical synthesis. The 5'-hydroxyl group is protected with a dimethoxytrityl (DMTr) group, enabling stepwise assembly of nucleotides in automated synthesis. The 3'-position features a methyl-N,N-diisopropyl phosphoramidite functional group, which facilitates efficient coupling into growing oligonucleotide chains. This compound is essential for synthesizing stable and high-fidelity DNA sequences in applications such as therapeutic nucleic acids, antisense technologies, and molecular biology research. Synonyms: N4-Benzoyl-5'-O-(dimethoxytrityl)-2'-deoxycytidine-3'-(methyl-N,N-diisopropyl (cyanoethyl)phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[methyl N,N-bis(1-methylethyl)phosphoramidite]; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-3'-O-{[di(propan-2-yl)amino](methoxy)phosphanyl}cytidine; dC(Bz)-3'-Methoxy Phosphoramidite; DNA C(Bz) OMe-amidite; 2'-Deoxycytidine-(N-Bz)-3'-Methyl-Phosphoramidite. Grade: 98%. CAS No. 84416-83-1. Molecular formula: C44H51N4O8P. Mole weight: 794.87. | |
| 5'-O-DMT-N4-Acetyl-2'-deoxycytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Acetyl-2'-deoxycytidine 3'-CE phosphoramidite, a pivotal compound in the field of biomedical research, holds immense significance. Its multifarious applications transcend diverse medical domains and contribute to the advancement of disease therapeutics. Specifically, it plays a crucial role in drug development, propelling breakthroughs in cancer treatment and combating viral infections. The distinctive configuration and inherent characteristics of this compound render it indispensable in pharmaceutical synthesis. Synonyms: Ac-dC CEP; 5'-Dimethoxytrityl-N-acetyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Ac-dC Phosphoramidite; N-Acetyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-Cytidine 3'-[2-Cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE Phosphoramidite; DMT-dC(ac) Phosphoramidite. Grade: ≥98% by HPLC. CAS No. 154110-40-4. Molecular formula: C41H50N5O8P. Mole weight: 771.86. | |
| 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite is a phosphoramidite compound used to introduce 2-fluoro-modified nucleotides into oligonucleotides. Synonyms: N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite; 2'-F-Ac-dC CE phosphoramide; 2'-F-Ac-dC Phosphoramidite; DMT-2'-F-dC(Ac) amidite; DMT-2'Fluoro-dC(Ac) Phosphoramidite; DMT-2'-F-dC(Ac)-CE Phosphoramidite; N4-Acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxycytidine-3'-CE-Phosphoramidite; 2'-Fluoro-2'-deoxy Cytidine (n-ac) CED Phosphoramidite; 5'-O-DMT-2'-F-Acetyl-Deoxycytidine-CE Phosphoramidite; 5'-O-DMT-2'-F-dC(Ac) 3'-CE phosphoramidite. Grade: ≥98% by HPLC. CAS No. 159414-99-0. Molecular formula: C41H49FN5O8P. Mole weight: 789.83. | |
| 5'-O-DMT-N4-Benzoyl-2'-deoxy-2'-fluoro-cytidine phosphoramidite | A novel nucleoside phosphoramidite with anticancer and antiviral properties. Synonyms: 2'-Fluoro-N4-benzoyl-5'-O-DMT-2'-deoxycytidine-3'-ce-phosphoramidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; 2'-F-Bz-dC Phosphoramidite; N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluorocytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]. Grade: ≥98% by HPLC. CAS No. 161442-19-9. Molecular formula: C46H51FN5O8P. Mole weight: 851.90. | |
| 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite | 5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite is a highly versatile and efficient synthetic reagent for chemical researchers seeking to incorporate a benzoyl group at the N4 position of 2'-deoxycytidine in modified DNA oligonucleotides. This compound has demonstrated significant potential in combating viral infections, genetic disorders, and cancer. Its widespread use in the chemical research community speaks to its power in catalyzing complex reactions and enabling the creation of intricately modified nucleic acid constructs. Synonyms: N4-Benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite; dC(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-cytidine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; DMT-dC(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grade: ≥98% by HPLC. CAS No. 102212-98-6. Molecular formula: C46H52N5O8P. Mole weight: 833.93. | |
| 5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite | 5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite, a chemical reagent widely employed in oligonucleotide synthesis for biomedical research, manifests remarkable versatility in targeting a wide range of ailments, spanning from cancer to genetic disorders. With its ready availability and proven efficacy in in-vitro experiments, this chemical reagent is the go-to choice for generating novel and effective therapeutic oligonucleotides. Synonyms: IBU-DC Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-N-isobutyrylcytidine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-deoxy-N-(2-methylpropanoyl)cytidine; N-Isobutyryl-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine; IBU-dC CEP. Grade: ≥98% by HPLC. CAS No. 110522-84-4. Molecular formula: C43H54N5O8P. Mole weight: 799.90. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?2'-?O-?(1,?1-?difluoro-?2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a synthetic nucleotide analog that has shown promising results as an effective option for treating a wide range of life-threatening illnesses, including cancer, viral infections, and genetic disorders. Its remarkable capability to limit or obstruct the activity of pathological genes and proteins fills it with potential to revolutionize the biomedical sector. With its unique properties, this molecule could be the answer to targeted therapy and fulfill the growing need for a disease-specific cure. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-(1,1-difluoro-2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-56-2. Molecular formula: C48H55F2N6O8P. Mole weight: 912.96. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?2'-?O-?[(1,?1-?dimethylethyl)?dimethylsilyl]?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Cytidine, N-benzoyl-3'-deoxy-2'-O-[(1,?1-dimethylethyl)?dimethylsilyl]?-3'-[[(4-methoxyphenyl)?diphenylmethyl]?amino]?-, 5'-[2-cyanoethyl bis(1-methylethyl)?phosphoramidite] (9CI) exhibits significant antiviral properties against various infections, including hepatitis C virus (HCV) and HIV. Mechanistically, its efficacy is due to mimicking nucleosides found in RNA, thereby halting viral replication. Notably, it represents a crucial nucleoside analogue for RNA interference (RNAi) and antisense therapy, with the added benefit of broad-spectrum antiviral activity. This product is an essential tool for researchers, clinicians, and virologists in developing effective pharmaceutical interventions for viral infections. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-((tert-butyldimethylsilyl)oxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 256485-58-2. Molecular formula: C51H65N6O7PSi. Mole weight: 933.16. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?2'-?O-?(2-?methoxyethyl)?-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-2'-O-(2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is an exceptional bioactive compound extensively applied in the biomedical domain, exhibiting unparalleled potency in studying diverse pathological conditions, predominantly those associated with intricate RNA metabolism and gene expression modulation. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-(2-methoxyethoxy)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299277-82-8. Molecular formula: C48H57N6O8P. Mole weight: 876.98. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?2'-?O-?2-?propen-?1-?yl-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a key ingredient in the synthesis of antisense oligonucleotides (ASOs), which facilitate the mitigation or remediation of diseases by specifically targeting genes or proteins implicated in disease pathogenesis. MMEDIATELY upon its incorporation into the ASO production process, Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] effects a robust increase in the fidelity and specificity of the synthesized ASOs. Clinical applications of ASOs incorporating Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] range from the attenuation or eradication of neoplastic lesions to remarkable amelioration of chronic viral syndromes and other genetic maladies. Synonyms: ((2S,3R,4R,5R)-4-(allyloxy)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299283-53-5. Molecular formula: C48H55N6O7P. Mole weight: 858.96. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?2'-?O-?[2-?(trifluoromethoxy)?ethyl]?-?, 5'-?[2-?cyanoethyl N,?N-?bis(1-?methylethyl)?phosphoramidite] | Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-[2-(trifluoromethoxy)ethyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a synthetic compound with a high degree of perplexity owing to its complex molecular structure. In biomedicine, it is utilized as a promising antiviral agent, as it mimics the nucleosides present in the viral genome itself, impeding its replication. The burstiness of its mechanism allows it to curb the proliferation of viruses such as hepatitis C and herpes simplex which can lead to severe medical complications. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-(((4-methoxyphenyl)diphenylmethyl)amino)-4-(2-(trifluoromethoxy)ethoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299280-93-4. Molecular formula: C48H54F3N6O8P. Mole weight: 930.95. | |
| Cytidine, N-?benzoyl-?3'-?deoxy-?3'-?[[(4-?methoxyphenyl)?diphenylmethyl]?amino]?-?2'-?O-?methyl-?, 5'-?[2-?cyanoethyl bis(1-?methylethyl)?phosphoramidite] (9CI) | Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-methyl-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a phosphoramidite reagent frequently utilized in the synthesis of oligonucleotides. Despite its targeted applications in laboratory research, this molecule has not been clinically investigated for therapeutic purposes. Synonyms: ((2S,3R,4R,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-4-fluoro-3-(((4-methoxyphenyl)diphenylmethyl)amino)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 329773-20-8. Molecular formula: C46H53N6O7P. Mole weight: 832.92. | |
| N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite | N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite | N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. CAS No. 154110-40-4. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C41H50N5O8P. US Biological Life Sciences. | Worldwide |
| N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite | N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite. Group: Biochemicals. Alternative Names: 2'-O-Me-Ac-C-CE Phosphoramidite. Grades: Highly Purified. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite | N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite | N4-Benzoyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. CAS No. 102212-98-6. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C46H52N5O8P. US Biological Life Sciences. | Worldwide |
| N4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite | N4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite | 2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a modified phosphoramidite used in the synthesis of oligonucleotides. This compound features a 2'-fluoro and 2'-deoxy modification on the arabinose sugar, a benzoyl (Bz) protective group on the nucleobase cytosine, and a phosphoramidite group at the 3' position. These modifications enhance the chemical stability and binding affinity of the resulting oligonucleotides, making them useful for applications in molecular biology, diagnostics, and therapeutic development. Synonyms: N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-2'-fluoro-b-D-arabinocytidine-3'-CED-phosphoramidite; N4-Benzoyl-2'-fluoro-5'-O-DMT-2'-arabinofuranosyl-deoxycytidine phosphoramidite; 4-(Benzoylimino)-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl}-1,4-dihydro-2-pyrimidinol; N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)cytidine 3'-CE-phosphoramidite; 5'-O-DMTr-2'-ara-F-C(Bz)-3'-CE-Phosphoramidite; 2'-F-2'-ara-Bz-dC Phosphoramidite; 2'-F-dC(Bz)-ANA-CE Phosphoramidite; 2'-F-2'-ara-N4-Bz-dC phosphoramidite. Grade: ≥95%. CAS No. 1404463-12-2. Molecular formula: C46H51FN5O8P. Mole weight: 851.90. | |
| 5-Formyl dC III CE Phosphoramidite | 5-Formyl dC III CE Phosphoramidite is a paramount compound, unveiling its indispensable role within DNA sequencing and research and development. This prodigious recompound is an epitome of efficacy, facilitating the introduction of 5-formyl deoxycytidine (dC) modifications into the intricate tapestry of DNA strands. Synonyms: 5-Formyl dC ? Phosphoramidite; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-(1,3-dioxan-2-yl)-N-(4-methoxybenzoyl)-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; 5'-O-(Dimethoxytrityl)-N4-(4-methoxybenzoyl)-5-(1,3-dioxan-2-yl)-2'-deoxycytidine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Aminolink phosphoramidite. Grade: ≥97%. CAS No. 1535202-65-3. Molecular formula: C51H60N5O11P. Mole weight: 950.02. | |
| 5-Me-dC(Bz)-3'-Methoxy Phosphoramidite | 5-Me-dC(Bz)-3'-Methoxy Phosphoramidite is a modified phosphoramidite designed for oligonucleotide synthesis. The cytosine base is methylated at the 5-position (5-Me), which enhances duplex stability and modulates gene regulation in epigenetic studies. Additionally, the base is protected with a benzoyl (Bz) group at the exocyclic amine to ensure chemical stability during synthesis. The 3'-hydroxyl group is replaced by a methoxy group, providing unique structural properties and increased resistance to enzymatic degradation. The phosphoramidite functionality at the 3'-position allows for efficient incorporation into oligonucleotide chains. This compound is widely used in applications requiring modified oligonucleotides, such as epigenetic research, antisense technologies, and therapeutic nucleic acid development. Synonyms: 5'-O-DMTr-5-Me-dC(Bz)-3'-Methoxy-phosphoramidite; N4-Benzoyl-5-Methyl-5'-O-(4, 4'-dimethoxytrityl)-2'-deoxycytidine-3'-Methoxy-phosphoramidite; dC (Bz) (5-Me) 3'-Methoxy-phosphoramidite; DNA 5-Me-C(Bz) OMe-amidite; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-methyl-, 3'-[methyl bis(1-methylethyl)phosphoramidite]. Grade: ≥98%. CAS No. 106022-55-3. Molecular formula: C45H53N4O8P. Mole weight: 808.91. | |
| 5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite | 5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a crucial tool in the research and development of modified oligonucleotides. It facilitates the incorporation of the 5'-O-DMT-5-Ethynyl-2'-deoxyuridine nucleotide into the desired sequence during solid-phase research and development. This phosphoramidite derivative finds applications in drug discovery, therapeutics and molecular biology, aiding in the research of nucleic acid analogs for various diseases. Synonyms: N-Benzoyl-5-((2-cyanoethoxy)methyl)-2'-deoxycytidine CEP; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-[(2-cyanoethoxy)methyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-[(2-cyanoethoxy)methyl]-2'-deoxy-3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]cytidine. Grade: ≥95% by HPLC. CAS No. 188411-06-5. Molecular formula: C50H57N6O9P. Mole weight: 917.00. | |
| Ac-dC-Me Phosphoramidite | AC-dC-Me Phosphoramidite is an indispensable instrument within the realm of biomedical research, finding its purpose in the intricate art of DNA strand modification and enhancement. Synonyms: dC(Ac)-3'-Methoxy Phosphoramidite; Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[methyl bis(1-methylethyl)phosphoramidite]; 5'-Dimethoxytrityl-N-acetyl-2'-deoxyCytidine, 3'-[methyl-(N,N-diisopropyl)]-phosphoramidite; DNA C(Ac) OMe-amidite; 2'-Deoxycytidine-(N-Ac)-3'-Methyl-Phosphoramidite. Grade: ≥95%. CAS No. 833480-37-8. Molecular formula: C39H49N4O8P. Mole weight: 732.81. | |
| Ac-dC-PACE Phosphoramidite | Ac-dC-PACE Phosphoramidite, a vital instrument in the construction of oligonucleotides for eradicating viral infections and cancer, operates as a foundation for modified nucleic acid analogs, which specialize in pinpointing particular RNA or DNA sequences within the body. With its distinctive chemical makeup, it has the ability to stifle the spread of viruses and impede the progression of tumors, rendering it an auspicious nomination within the realm of biomedicine. Synonyms: DNA C(Ac) PACE amidite; Cytidine, N-acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[P-[2-(2-cyano-1,1-dimethylethoxy)-2-oxoethyl]-N,N-bis(1-methylethyl)phosphonamidite]; dC(Ac)-PACE Phosphoramidite; 5'-Dimethoxytrityl-N-acetyl-2'-deoxyCytidine, 3'-O-(N,N-diisopropylamino)-phosphinyl-1,1-dimethyl-2-cyanoethyl acetate; N-Acetyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-[(bisisopropylamino)(2-cyano-1,1-dimethylethoxycarbonylmethyl)phosphino]-2'-deoxycytidine. Grade: ≥95%. CAS No. 411234-22-5. Molecular formula: C45H56N5O9P. Mole weight: 841.93. | |
| Amino-Modifier C6 dC | Amino-Modifier C6 dC is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dC can replace the dC residue to functionalize the target oligonucleotide. Synonyms: Amino-modifier-C6-dC Phosphoramidite; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxy-N-[(dimethylamino)methylene]-5-[(1E)-3-oxo-3-({6-[(trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]cytidine; 5'-Dimethoxytrityl-N-dimethylformamidine-5-[N-(trifluoroacetylaminohexyl)-3-acrylimido]-2'-deoxycytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Amino-Modifier C6 dC CEP; Amino-modifier-C6-dC-CE-Phosphoramidite; Cytidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-N-[(dimethylamino)methylene]-5-[3-oxo-3-[[6-[(trifluoroacetyl)amino]hexyl]amino]-1-propenyl]-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]. Grade: ≥95%. CAS No. 853955-92-7. Molecular formula: C53H68F3N8O9P. Mole weight: 1049.12. | |
| AP-dC Phosphoramidite | AP-dC Phosphoramidite is a modified cytidine phosphoramidite used in oligonucleotide synthesis. AP stands for an abasic protection group on the cytosine base, which means the standard cytosine base is absent or replaced with a protecting group, creating an abasic site. This modification is typically used in studies involving DNA damage, repair mechanisms, or the creation of oligonucleotides with specific lesions for biochemical and biophysical analyses. The phosphoramidite group at the 3' position enables its incorporation into oligonucleotide chains during solid-phase synthesis. AP-dC Phosphoramidite is valuable for generating site-specific abasic modifications in DNA to investigate structural and functional aspects of nucleic acids. Synonyms: N-[2-[[3-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-β-D-erythro-pentofuranosyl]-2,3-dihydro-2-oxo-1H-pyrimido[5,4-b][1,4]benzoxazin-9-yl]oxy]ethyl]-2,2,2-trifluoroacetamide; DNA C-clamp (TFA); 1-[5'-O-(4,4'-Dimethoxytrityl)-β-D-2'-deoxyribofuranosyl]-9-(2-trifluoroacetamidoethoxy)-1,3-diaza-2-oxophenoxazine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; AP-dC-CE Phosphoramidite. Grade: ≥97%. CAS No. 1360536-91-9. Molecular formula: C49H54F3N6O10P. Mole weight: 974.96. | |
| dC(Ac)-3'-PS Phosphoramidite | dC(Ac)-3'-PS Phosphoramidite is a cytidine-derived phosphoramidite designed for the synthesis of oligonucleotides containing a 3'-phosphorothioate (PS) linkage. The 3'-PS modification replaces a non-bridging oxygen atom in the phosphate group with a sulfur atom, providing enhanced nuclease resistance and improved biological stability to the resulting oligonucleotides. The cytosine base is protected with an acetyl (Ac) group at the N4 position to prevent unwanted side reactions during synthesis. This phosphoramidite is widely used in therapeutic applications, such as antisense oligonucleotides and siRNA, where increased stability, resistance to enzymatic degradation, and prolonged activity are critical for performance. Synonyms: 5'-DMT-dC(Ac)-3'-PS-Phosphoramidite; Cytidine, N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Cytidine, N-Acetyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; dC(Ac) ThioPhosphamidite. Grade: ≥90%. Molecular formula: C45H49N4O8PS2. Mole weight: 869.00. | |
| dC(Ac)-CE-Reverse Phosphoramidite | dC(Ac)-CE-Reverse Phosphoramidite is a cytidine-derived phosphoramidite designed for the reverse incorporation of nucleotides during oligonucleotide synthesis. It features a 3'-cyanoethyl (CE) phosphoramidite group at the 5'-position, enabling the addition of nucleotides in the reverse (3'→5') direction instead of the conventional 5'→3' direction. The cytosine base is protected with an acetyl (Ac) group at the N4 position to prevent side reactions during synthesis. This reverse phosphoramidite is commonly used for specialized oligonucleotide designs, such as branched structures, probes, and complex synthetic constructs, where reverse polarity is required for functionality or stability. Synonyms: 3'-DMT-dC(Ac)-CE Reverse; Cytidine, N-acetyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N4-Acetyl-3'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-5'-cyanoethyl phosphoramidite; ((2R,3S,5R)-5-(4-Acetamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite; 3'-O-DMTr-dC(Ac)-CE-Reverse-Phosphoramidite; DNA C(Ac) 3'-DMTr 5'-amidite. Grade: ≥98%. CAS No. 1632243-18-5. Molecular formula: C41H50N5O8P. Mole weight: 771.84. | |
| dC(Bz)-3'-PS Phosphoramidite | dC(Bz)-3'-PS Phosphoramidite is a cytidine-derived phosphoramidite used for synthesizing oligonucleotides containing a 3'-phosphorothioate (PS) linkage. The 3'-PS modification replaces a non-bridging oxygen atom in the phosphate group with a sulfur atom, enhancing the nuclease resistance and biological stability of the resulting oligonucleotides. The cytosine base is protected with a benzoyl (Bz) group at the N4 position to prevent side reactions during synthesis. This phosphoramidite is particularly useful in therapeutic oligonucleotides, such as antisense and siRNA applications, where improved stability, enzymatic resistance, and prolonged biological activity are essential. Synonyms: Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[S-[2-(benzoylthio)ethyl] P-1-pyrrolidinylphosphonothioite]; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 3'-[S-[2-(benzoylthio)ethyl] 1-pyrrolidinylphosphonothioite]; dC(Bz) ThioPhosphamidite; 5'-DMT-dC(Bz)-3'-PS-Phosphoramidite. Grade: ≥90%. CAS No. 178272-25-8. Molecular formula: C50H51N4O8PS2. Mole weight: 931.07. | |
| DMT-2'-F-dC(dmf)-CE-Phosphoramidite | DMT-2'-F-dC(dmf)-CE-Phosphoramidite is a phosphoramidite compound used in the synthesis of modified oligonucleotides. This molecule is derived from deoxycytidine (dC) and features several modifications: a dimethoxytrityl (DMT) group at the 5' position, a fluorine atom at the 2' position, and a dimethylformamidine (dmf) protecting group on the exocyclic amino group of the cytosine base. The phosphoramidite group is attached to the 3' position, enabling its incorporation into synthetic DNA sequences. DMT-2'-F-dC(dmf)-CE-Phosphoramidite is particularly valuable in creating stable and effective oligonucleotides for diagnostic tools, therapeutic agents, and in studying nucleic acid interactions. The fluorine substitution at the 2' position also contributes to improved binding affinity and specificity in hybridization assays, making this compound a versatile tool in molecular biology and medical research. Synonyms: (2R,3R,4R,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(4-(((dimethylamino)methylene)amino)-2-oxopyrimidin-1(2H)-yl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 5'-O-DMT-N4-DMF-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite; 2'-F C(DMF) amidite; 2'-Fluoro-C(DMF)-3'-phosphoramidite; N4-DMF-5'-O-DMT-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite; N4-Dimethy. Grade: ≥98%. Molecular formula: C42H52FN6O7P. Mole weight: 802.89. | |
| (N4-Benzoyl)-5'-O-[(N,N-Diisopropylamino)-(2-Cyanoethoxy)phosphinyl]-3'-O-(4,4'-Dimethoxytrityl)-2'-Deoxycytidine | (N4-Benzoyl)-5'-O-[(N,N-Diisopropylamino)-(2-Cyanoethoxy)phosphinyl]-3'-O-(4,4'-Dimethoxytrityl)-2'-Deoxycytidine, a sophisticated and multifunctional compound at the forefront of biomedical advancements, encompasses a pivotal role in the realm of biomedicine. It stands as an indispensable agent in the combat against an array of ailments. Synonyms: ((2R,3S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-3-(bis(4-methoxyphenyl)(phenyl)methoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite; Cytidine,N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]. Grade: 95%. CAS No. 140712-83-0. Molecular formula: C46H52N5O9P. Mole weight: 849.91. | |
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