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2,3-Anhydro-N4-benzoyl-2-deoxycytidine 5-CE phosphoramidite, a highly essential oligonucleotide synthesis component utilized within the biomedical industry, has become tremendously emphasized, due to its diverse and efficient reactivity. Its notable characteristics are highly appreciated in scientific research, while its wide application, ranging from cancer treatment to viral infection mitigation, continues to garner the utmost respect. Synonyms: 2,3'-Anhydro-N4-benzyl-2'-deoxy-D-cytidine 5'-CE phosphoramidite. Molecular formula: C25H32N5O5P. Mole weight: 513.54.
2'-Deoxy-5'-O-DMT-N4-(hexyloxylevulinyl)-5-methylcytidine 3'-CE phosphoramidite - a versatile reagent imperative for the synthesis of modified oligonucleotides and crucial for the field of biomedical research. Its significance is profound in understanding the association between epigenetic modifications, gene expression, and the progression of diseases, including cancer. The phosphoramidite empowers the smooth incorporation of modified cytidine residues into oligonucleotides, enabling the exploration of their impact on the biological system. Synonyms: 2'-Deoxy-5'-O-DMT-N4-(hexyloxylevulinyl)-5-methyl-D-cytidine 3'-CE-phosphoramidite; 5'-O-DMT-N4-(hexyloxylevulinyl)-5-methyl-2'deoxycytidine 3'-CE-phosphoramidite. Molecular formula: C51H68N5O10P. Mole weight: 942.11.
2'-Deoxy-N4-DMF-5'-O-DMT-pseudoisocytidine 3'-CE phosphoramidite is an essential phosphoramidite derivative for oligonucleotide research and development, is extensively employed for advancing biomedical research and drug development. Its primary role lies in the modification of nucleic acids, empowering investigations on DNA and RNA structures, interactions, and functions. Synonyms: 2'-Deoxy-N4-DMF-5'-O-DMT-pseudoiso-D-cytidine 3'-CE phosphoramidite; N4-DMF-5'-O-DMT-2'-deoxypseudoisocytidine 3'-CE phosphoramidite. Grades: 95%. CAS No. 307314-31-4. Molecular formula: C42H53N6O7P. Mole weight: 784.88.
5'-O-DMT-N4-Acetyl-2'-deoxycytidine 3'-CE phosphoramidite, a pivotal compound in the field of biomedical research, holds immense significance. Its multifarious applications transcend diverse medical domains and contribute to the advancement of disease therapeutics. Specifically, it plays a crucial role in drug development, propelling breakthroughs in cancer treatment and combating viral infections. The distinctive configuration and inherent characteristics of this compound render it indispensable in pharmaceutical synthesis. Synonyms: Ac-dC CEP; 5'-Dimethoxytrityl-N-acetyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; Ac-dC Phosphoramidite; N-Acetyl-5'-O-[bis(4-methoxyphenyl)?phenylmethyl]?-2'-deoxy-Cytidine 3'-[2-Cyanoethyl N,?N-bis(1-methylethyl)?phosphoramidite]; N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE Phosphoramidite; DMT-dC(ac) Phosphoramidite. Grades: ≥98% by HPLC. CAS No. 154110-40-4. Molecular formula: C41H50N5O8P. Mole weight: 771.86.
5'-O-DMT-N4-Acetyl-2'-fluoro-2'-deoxy-cytidine 3'-CE phosphoramidite is a phosphoramidite compound used to introduce 2-fluoro-modified nucleotides into oligonucleotides. Synonyms: N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite; 2'-F-Ac-dC CE phosphoramide; 2'-F-Ac-dC Phosphoramidite; Dmt-2'-f-dc(ac) amidite; DMT-2'Fluoro-dC(ac) Phosphoramidite. Grades: ≥98% by HPLC. CAS No. 159414-99-0. Molecular formula: C41H49FN5O8P. Mole weight: 789.83.
5'-O-DMT-N4-Benzoyl-2'-deoxycytidine 3'-CE phosphoramidite is a highly versatile and efficient synthetic reagent for chemical researchers seeking to incorporate a benzoyl group at the N4 position of 2'-deoxycytidine in modified DNA oligonucleotides. This compound has demonstrated significant potential in combating viral infections, genetic disorders, and cancer. Its widespread use in the chemical research community speaks to its power in catalyzing complex reactions and enabling the creation of intricately modified nucleic acid constructs. Synonyms: N4-Benzoyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite; dC(Bz) CEP; 5'-Dimethoxytrityl-N-benzoyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-cytidine 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]; N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine-3'-O-[O-(2-cyanoethyl)-N,N'-diisopropylphosphoramidite]; DMT-dC(bz) Phosphoramidite; 5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite. Grades: ≥98% by HPLC. CAS No. 102212-98-6. Molecular formula: C46H52N5O8P. Mole weight: 833.93.
5'-O-DMT-N4-Isobutyryl-2'-deoxycytidine-3'-CE Phosphoramidite, a chemical reagent widely employed in oligonucleotide synthesis for biomedical research, manifests remarkable versatility in targeting a wide range of ailments, spanning from cancer to genetic disorders. With its ready availability and proven efficacy in in-vitro experiments, this chemical reagent is the go-to choice for generating novel and effective therapeutic oligonucleotides. Synonyms: IBU-DC Phosphoramidite; 5'-O-[Bis (4-methoxyphenyl) (phenyl)methyl]-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-2'-deoxy-N-isobutyrylcytidine; 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-{(2-cyanoethoxy)[di(propan-2-yl)amino]phosphanyl}-2'-deoxy-N-(2-methylpropanoyl)cytidine; N-Isobutyryl-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-5'-O- (4, 4'-dimethoxytrityl)-2'-deoxycytidine; IBU-dC CEP. Grades: ≥98% by HPLC. CAS No. 110522-84-4. Molecular formula: C43H54N5O8P. Mole weight: 799.90.
Cytidine, N-benzoyl-3'-deoxy-2'-O-(1,1-difluoro-2-methoxyethyl)-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a synthetic nucleotide analog that has shown promising results as an effective option for treating a wide range of life-threatening illnesses, including cancer, viral infections, and genetic disorders. Its remarkable capability to limit or obstruct the activity of pathological genes and proteins fills it with potential to revolutionize the biomedical sector. With its unique properties, this molecule could be the answer to targeted therapy and fulfill the growing need for a disease-specific cure. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -4- (1, 1-difluoro-2-methoxyethoxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299279-56-2. Molecular formula: C48H55F2N6O8P. Mole weight: 912.96.
Cytidine, N-benzoyl-3'-deoxy-2'-O-[ (1, ?1-dimethylethyl) ?dimethylsilyl]?-3'-[[ (4-methoxyphenyl) ?diphenylmethyl]?amino]?-, 5'-[2-cyanoethyl bis(1-methylethyl)?phosphoramidite] (9CI) exhibits significant antiviral properties against various infections, including hepatitis C virus (HCV) and HIV. Mechanistically, its efficacy is due to mimicking nucleosides found in RNA, thereby halting viral replication. Notably, it represents a crucial nucleoside analogue for RNA interference (RNAi) and antisense therapy, with the added benefit of broad-spectrum antiviral activity. This product is an essential tool for researchers, clinicians, and virologists in developing effective pharmaceutical interventions for viral infections. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -4- ( (tert-butyldimethylsilyl) oxy) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 256485-58-2. Molecular formula: C51H65N6O7PSi. Mole weight: 933.16.
Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a key ingredient in the synthesis of antisense oligonucleotides (ASOs), which facilitate the mitigation or remediation of diseases by specifically targeting genes or proteins implicated in disease pathogenesis. MMEDIATELY upon its incorporation into the ASO production process, Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] effects a robust increase in the fidelity and specificity of the synthesized ASOs. Clinical applications of ASOs incorporating Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-2-propen-1-yl-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] range from the attenuation or eradication of neoplastic lesions to remarkable amelioration of chronic viral syndromes and other genetic maladies. Synonyms: ( (2S, 3R, 4R, 5R) -4- (allyloxy) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299283-53-5. Molecular formula: C48H55N6O7P. Mole weight: 858.96.
Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-[2-(trifluoromethoxy)ethyl]-, 5'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite] is a synthetic compound with a high degree of perplexity owing to its complex molecular structure. In biomedicine, it is utilized as a promising antiviral agent, as it mimics the nucleosides present in the viral genome itself, impeding its replication. The burstiness of its mechanism allows it to curb the proliferation of viruses such as hepatitis C and herpes simplex which can lead to severe medical complications. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) -4- (2- (trifluoromethoxy) ethoxy) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 2299280-93-4. Molecular formula: C48H54F3N6O8P. Mole weight: 930.95.
Cytidine, N-benzoyl-3'-deoxy-3'-[[(4-methoxyphenyl)diphenylmethyl]amino]-2'-O-methyl-, 5'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI) is a phosphoramidite reagent frequently utilized in the synthesis of oligonucleotides. Despite its targeted applications in laboratory research, this molecule has not been clinically investigated for therapeutic purposes. Synonyms: ( (2S, 3R, 4R, 5R) -5- (4-benzamido-2-oxopyrimidin-1 (2H) -yl) -4-fluoro-3- ( ( (4-methoxyphenyl) diphenylmethyl) amino) tetrahydrofuran-2-yl) methyl (2-cyanoethyl) diisopropylphosphoramidite. CAS No. 329773-20-8. Molecular formula: C46H53N6O7P. Mole weight: 832.92.
N4-Acetyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite, a versatile biomedicine compound, proficiently synthesizes modified oligonucleotides for diverse applications like drug delivery, gene therapy, and molecular diagnostics. This compound facilitates the efficient integration of N4-acetylcytidine alterations into nucleic acid sequences, presenting promising therapeutic advantages in combating diseases including cancer and viral infections. Synonyms: 2'-Deoxy-D-cytidine 5'-CE phosphoramidite. Molecular formula: C41H50N5O8P. Mole weight: 771.84.
N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine 3'-Me phosphoramidite, an indispensable asset within the biomedical realm, assumes a pivotal role as a foundational component in the fabrication of altered RNA or DNA entities. This derivative of phosphoramidite facilitates the seamless integration of N4-acetylcytidine into oligonucleotides, thereby granting researchers the means to scrutinize the ramifications that modified nucleotides impose on gene expression and regulation. Synonyms: Ac-dC-Me Phosphoramidite; N4-Acetyl-2'-deoxy-5'-O-DMT-D-cytidine 3'-Me phosphoramidite; N4-Acetyl-5'-O-DMT-2'-deoxycytidine 3'-Me phosphoramidite. Molecular formula: C39H49N4O8P. Mole weight: 732.80.
N4-Acetyl-5-Aza-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is a synthetic compound utilized in the creation of modified oligonucleotides for scientific investigations. Its application is principally in the biomedicine area for genetic analysis, with particular regards to epigenetic dynamics and gene regulation. The dynamic nature this product imbues can hold therapeutic prospects, especially in the realm of genetic sequences from cancerous and viral strains. Molecular formula: C40H49N6O8P. Mole weight: 772.83.
N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine 5'-CE phosphoramidite, a vital chemical compound harnessed in biomedicine, holds immense potential in oligonucleotide and RNA synthesis. Its pivotal role as a fundamental constituent in nucleic acid-based drug advancement, encompassing gene therapy and targeted therapy, cannot be overlooked. Through its precise affinity towards DNA and RNA sequences, this phosphoramidite assists in tailored interventions for diverse ailments, rendering it an indispensable asset within the biomedical domain. Molecular formula: C46H52N5O8P. Mole weight: 833.93.
N4-Benzoyl-2'-deoxy-5'-O-DMT-5-iodocytidine 3'-CE phosphoramidite, an indispensable entity within the realm of biomedical research, assumes a pivotal role. Its application predominantly lies in the amalgamation of nucleotides, thereby enabling an examination of DNA alterations and configuration. Forging a significant pathway in drug exploration and genetic engineering investigations concerning afflictions such as cancer, viral infections, and hereditary anomalies, this product fosters an enhanced insight into multifarious intricate biological mechanisms. Synonyms: N4-Benzoyl-2'-deoxy-5'-O-DMT-5-iodo-D-cytidine 3'-CE phosphoramidite; N4-Benzoyl-5'-O-DMT-5-iodo-2'-deoxycytidine 3'-CE phosphoramidite. Grades: 97%. Molecular formula: C46H51IN5O8P. Mole weight: 959.83.
N4-Benzoyl-2'-deoxy-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is widely used in the biomedical industry as a building block for synthesizing modified nucleotides. It plays a crucial role in the research of pharmaceutical drugs targeting specific diseases, such as cancer and viral infections. Synonyms: 5'-Dimethoxytrityl-N-benzoyl-5-methyl-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; N4-Bz-5'-DMT-5-Me-dC phosphoramidite; N4-Benzoyl-2'-Deoxy-5'-O-DMT-5-methyl-D-cytidine 3'-CE phosphoramidite; N4-Benzoyl-5'-O-DMT-5-methyl-2'-Deoxycytidine 3'-CE phosphoramidite; 5-Me-dC-CE Phosphoramidite. Grades: ≥98% by HPLC. CAS No. 105931-57-5. Molecular formula: C47H54N5O8P. Mole weight: 847.9.
N4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite is a paramount intermediate in synthesizing modified DNA and RNA oligonucleotides aimed for application in biomedicine. With promising possibilities for treating illnesses such as cancer, genetic disorders, autoimmune disorders, and viral infections, this reagent's virtuous purity and robustness render it a prodigious resource in molecular biology experimentation. Synonyms: N4-Benzoyl-5-bromo-2'-deoxy-5'-O-DMT-D-cytidine 3'-CE phosphoramidite; N4-Benzoyl-5-bromo-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite. Molecular formula: C46H51BrN5O8P. Mole weight: 912.8.
N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine 3'-CE phosphoramidite is an invaluable tool within the biomedical industry due to its pivotal role in the synthesis of customized oligonucleotides. By facilitating the efficient integration of N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine into DNA strands during solid-phase synthesis, this phosphoramidite exhibits immense potential in various domains such as gene therapy research, drug discovery, and the advancement of diagnostic probes targeting ailments like cancer, viral infections, and genetic disorders. Synonyms: N4-Benzoyl-5'-O-tert-butyldimethylsilyl-2'-deoxy-D-cytidine 3'-CE phosphoramidite. Molecular formula: C31H48N5O6PSi. Mole weight: 645.82.
N4-Benzyl-2'-deoxy-2'-fluoro-5'-O-tritylcytidine 3'-CE phosphoramidite, an indispensable compound in the biomedical sector, holds immense significance. Its application lies in the synthesis of nucleic acid-derived medications, particularly for combating viral infections and certain cancer variants. Synonyms: N4-Benzyl-2'-deoxy-2'-fluoro-5'-O-trityl-D-cytidine 3'-CE phosphoramidite; N4-Benzyl-2'-fluoro-5'-O-trityl-2'-deoxycytidine 3'-CE phosphoramidite. Molecular formula: C44H49FN5O5P. Mole weight: 777.88.
N4-Benzyl-2'-deoxy-5'-O-DMT-cytidine 3'-CE phosphoramidite: This biomedical product is essential for synthesizing modified oligonucleotides used in DNA and RNA research. It efficiently introduces N4-benzyl, 2'-deoxy, 5'-O-DMT, and 3'-CE phosphoramidite modifications into cytidine residues. These modified nucleotides are employed in studying gene expression, gene therapy, and drug development, ultimately contributing to advancements in treating various diseases such as cancer and genetic disorders. Synonyms: N4-Benzyl-2'-deoxy-5'-O-DMT-D-cytidine 3'-CE phosphoramidite; N4-Benzyl-5'-O-DMT-2'-deoxycytidine 3'-CE phosphoramidite. Molecular formula: C46H54N5O7P. Mole weight: 819.95.
N4-Benzyl-2'-deoxy-5'-O-MMT-cytidine 3'-CE phosphoramidite is a valuable compound widely used in the biomedical industry. It plays a crucial role in the synthesis of nucleoside analogs utilized for antiviral drug development, particularly for the research of viral diseases like hepatitand HIV. Synonyms: N4-Benzyl-2'-deoxy-5'-O-MMT-cytidine 3'-CE phosphoramidite; N4-Benzyl-5'-O-MMT-2'-deoxycytidine 3'-CE phosphoramidite. Molecular formula: C45H52N5O6P. Mole weight: 789.92.
N4-Benzyl-2'-deoxy-5'-O-tritylcytidine 3'-CE phosphoramidite, an invaluable biomedical asset, finds its purpose in oligonucleotide synthesis for progressive biomedical investigations and pharmaceutical advancements. Depicting its significance as a pivotal constituent, it facilitates the manipulation of cytidine residues thereby enabling discrete drug administration mechanisms and therapeutic approaches. Synonyms: N4-Benzyl-2'-deoxy-5'-O-trityl-D-cytidine 3'-CE phosphoramidite; N4-Benzyl-5'-O-trityl-2'-deoxycytidine 3'-CE phosphoramidite. Molecular formula: C44H50N5O5P. Mole weight: 759.89.
5'-O-DMT-5-Ethynyl-2'-deoxyuridine 3'-CE phosphoramidite is a crucial tool in the research and development of modified oligonucleotides. It facilitates the incorporation of the 5'-O-DMT-5-Ethynyl-2'-deoxyuridine nucleotide into the desired sequence during solid-phase research and development. This phosphoramidite derivative finds applications in drug discovery, therapeutics and molecular biology, aiding in the research of nucleic acid analogs for various diseases. Synonyms: N-Benzoyl-5-((2-cyanoethoxy)methyl)-2'-deoxycytidine CEP; Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-[(2-cyanoethoxy)methyl]-2'-deoxy-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]; N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-5-[(2-cyanoethoxy)methyl]-2'-deoxy-3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]cytidine. Grades: ≥95% by HPLC. CAS No. 188411-06-5. Molecular formula: C50H57N6O9P. Mole weight: 917.00.
Amino-Modifier C6 dC
Amino-Modifier C6 dC is designed for automatic synthesis. During oligonucleotide synthesis, the addition of the amino modifier dC can replace the dC residue to functionalize the target oligonucleotide. Synonyms: Amino-modifier-C6-dC Phosphoramidite; 5'-O-[Bis (4-methoxyphenyl) (phenyl)methyl]-3'-O-[ (2-cyanoethoxy) (diisopropylamino)phosphino]-2'-deoxy-N-[ (dimethylamino)methylene]-5-[ (1E)-3-oxo-3- ({6-[ (trifluoroacetyl)amino]hexyl}amino)-1-propen-1-yl]cytidine; 5'-Dimethoxytrityl-N-dimethylformamidine-5-[N-(trifluoroacetylaminohexyl)-3-acrylimido]-2'-deoxyCytidine, 3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite. Grades: 95%. CAS No. 853955-92-7. Molecular formula: C53H68F3N8O9P. Mole weight: 1049.12.
(N4-Benzoyl)-5'-O-[(N,N-Diisopropylamino)-(2-Cyanoethoxy)phosphinyl]-3'-O-(4,4'-Dimethoxytrityl)-2'-Deoxycytidine, a sophisticated and multifunctional compound at the forefront of biomedical advancements, encompasses a pivotal role in the realm of biomedicine. It stands as an indispensable agent in the combat against an array of ailments. Synonyms: ( (2R, 3S, 5R)-5- (4-benzamido-2-oxopyrimidin-1 (2H)-yl)-3- (bis (4-methoxyphenyl) (phenyl)methoxy)tetrahydrofuran-2-yl)methyl (2-cyanoethyl) diisopropylphosphoramidite; Cytidine,N-benzoyl-3'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-, 5'-[2-cyanoethylbis(1-methylethyl)phosphoramidite]. Grades: 95%. CAS No. 140712-83-0. Molecular formula: C46H52N5O9P. Mole weight: 849.91.
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