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Deoxyfuconojirimycin hydrochloride Deoxyfuconojirimycin hydrochloride is a specific competitive inhibitor of human liver α-L-fucosidase. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 210174-73-5. Pack Sizes: 5 mg. Product ID: HY-126306. MedChemExpress MCE
Deoxyfuconojirimycin Hydrochloride It is a potent and specific inhibitor of several alpha-L-fucosidases. Synonyms: (2S,3R,4S,5R)-2-Methyl-3,4,5-piperidinetriol Hydrochloride; 1,5-Dideoxy-1,5-imino-L-fucitol Hydrochloride; 1,2,6-Trideoxy-2,6-imino-D-galactitol Hydrochloride; L-fuco-Deoxynojirimycin Hydrochloride; 1-Deoxyfuconojirimycin Hydrochloride. Grades: 98%. CAS No. 210174-73-5. Molecular formula: C6H14ClNO3. Mole weight: 183.63. BOC Sciences 11
Deoxyfuconojirimycin Hydrochloride (DFJ) A powerful and specific inhibitor of several alpha-L-fucosidases. Deoxyfuconojirimycin (1,5-dideoxy-1,5-imino-L-fucitol) is a potent, specific and competitive inhibitor (Ki 1 x 10(-8) M) of human liver alpha-L-fucosidase (EC 3.2.1.51). Six structural analogues of this compound were synthesized and tested for their ability to inhibit alpha-L-fucosidase and other human liver glycosidases. It is concluded that the minimum structural requirement for inhibition of alpha-L-fucosidase is the correct configuration of the hydroxy groups at the piperidine ring carbon atoms 2, 3 and 4. Different substituents in either configuration at carbon atom 1 (i.e. 1 alpha- and beta-homofuconojirimycins) and at carbon atom 5 may alter the potency but do not destroy the inhibition of alpha-L-fucosidase. The pH-dependency of the inhibition by these amino sugars suggests very strongly that inhibition results from the formation of an ion-pair between the protonated inhibitor and a carboxylate group in the activÂ… Group: Biochemicals. Alternative Names: (2S,3R,4S,5R)-2-Methyl-3,4,5-piperidinetriol; 1,5-Dideoxy-1,5-imino-L-fucitol. Grades: Highly Purified. CAS No. 210174-73-5. Pack Sizes: 5mg, 10mg. Molecular Formula: C6H13NO3 HCl, Molecular Weight: 183.63. US Biological Life Sciences. USBiological 1
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