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A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: 2-[[4-[(3-Ethynylphenyl)amino]-7-(2-methoxyethoxy)-6-quinazolinyl]oxy]ethanol. Grades: > 95%. CAS No. 183321-86-0. Molecular formula: C21H21N3O4. Mole weight: 379.42.
Desmethyl Erlotinib
Desmethyl Erlotinib (OSI-420 free base) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor [1]. Desmethyl Erlotinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-420 free base; CP-373420. CAS No. 183321-86-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13256A.
Desmethyl Erlotinib derivative. Group: Biochemicals. Alternative Names: 6-(2-Acetoxy-ethoxy)-4-(3-ethynyl-phenylamino)-7-(2-methoxy-ethoxy)-quinazoline. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Desmethyl erlotinib carboxylate acid
Desmethyl erlotinib carboxylate acid. Group: Biochemicals. Alternative Names: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]. Grades: Highly Purified. CAS No. 882172-60-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C21H19N3O5. US Biological Life Sciences.
Worldwide
Desmethyl erlotinib carboxylate acid
Desmethyl erlotinib carboxylate acid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl]oxy]. Product Category: Heterocyclic Organic Compound. CAS No. 882172-60-3. Molecular formula: C21H19N3O5. Mole weight: 393.39. Product ID: ACM882172603. Alfa Chemistry ISO 9001:2015 Certified.
Desmethyl Erlotinib Carboxylate Acid
Cas No. 1170354-84-3.
Desmethyl Erlotinib, Free Base
A metabolite of Erlotinib, an anti cancer agent. Group: Biochemicals. Alternative Names: 2- [ [4- [ (3-Ethynylphenyl) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol; OSI-420; CP 373420. Grades: Highly Purified. CAS No. 183321-86-0. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Desmethyl Erlotinib hydrochloride
Desmethyl Erlotinib hydrochloride (OSI-420) is an active metabolite of Erlotinib. Erlotinib is a potent EGFR tyrosin kinase inhibitor [1]. Desmethyl Erlotinib (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: OSI-420; CP-373420 hydrochloride. CAS No. 183320-51-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-13256.
Erlotinib O-Desmethyl Metabolite Isomer
A metabolite of Erlotinib. Erlotinib is a tyrosine kinase inhibitor which acts on the epidermal growth factor receptor (EGFR), inhibiting EGFR-associated kinase activity. Synonyms: Erlotinib 7-O-Desmethyl Metabolite; 2-[[4-[(3-Ethynylphenyl)amino]-6-(2-methoxyethoxy)-7-quinazolinyl] oxy]ethanol. Grades: > 95%. CAS No. 183320-29-8. Molecular formula: C21H21N3O4. Mole weight: 379.42.
Erlotinib O-Desmethyl Metabolite Isomer (M14) HCl
OSI-420 (CP-473420) is an active metabolite of erlotinib which is an orally active EGFR tyrosin kinase inhibitor with IC50 of 2 and 20 nM for the inhibition of human EGFR and EGFR autophosphorylation in tumor cells. Uses: For research used only. Synonyms: OSI420; OSI-420; OSI 420; CP473420; CP-473420; CP 473420; Desmethyl Erlotinib. Grades: > 95%. CAS No. 183320-51-6. Molecular formula: C21H22ClN3O4. Mole weight: 415.874.
OSI-420-d4, Free Base (Desmethyl Erlotinib-d4)
A labeled metabolite of Erlotinib , an anti-cancer agent. Group: Biochemicals. Alternative Names: 2- [ [4- [ (3-Ethynylphenyl-d4) amino] -7- (2-methoxyethoxy) -6-quinazolinyl] oxy] ethanol; CP 373420. Grades: Highly Purified. CAS No. 1216420-11-9. Pack Sizes: 1mg. US Biological Life Sciences.
2, 2'- ( (4-Chloroquinazoline-6, 7-diyl)bis (oxy))diethanol is an impurtiy in the synthesis of Desmethyl Erlotinib which is a metabolite of Erlotinib (E625000), an anti cancer agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C12H13ClN2O4. US Biological Life Sciences.
Worldwide
OSI-413
OSI-413 is an impurity of Erlotinib, a selective epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor. Synonyms: OSI 413; OSI413; 7-(2'-Desmethyl) Erlotinib. Grades: >97%. CAS No. 183365-34-6. Molecular formula: C21H22ClN3O4. Mole weight: 415.87.
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