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Heterocyclic Organic Compound. Alternative Names: 4-[ (1E)-1-[4-[2- (methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol. CAS No. 114828-90-9. Molecular formula: C25H27NO2. Mole weight: 373.49. Appearance: White Solid. Purity: 0.96. IUPACName: 4-[ (E)-1-[4-[2- (methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol. Catalog: ACM114828909.
(E)-4-Hydroxy-N-desmethylTamoxifen
A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line. Group: Biochemicals. Alternative Names: 4-[ (1E) -1-[4-[2- (methylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol. Grades: Highly Purified. CAS No. 114828-90-9. Pack Sizes: 1mg. US Biological Life Sciences.
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(E/Z)-4,4-Dihydroxy-N-desmethylTamoxifen
A Tamoxifen analog. Group: Biochemicals. Alternative Names: (E/Z)-4-Hydroxy Endoxifen. Grades: Highly Purified. CAS No. 1217247-19-2. Pack Sizes: 1mg. US Biological Life Sciences.
A metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Alternative Names: E/Z Endoxifen, 4OHNDtam, 4-[1-[4-[2- (methylamino) ethoxy]phenyl]-2-phenyl-1-butenyl]phenol. Grades: Highly Purified. CAS No. 110025-28-0. Pack Sizes: 5mg. US Biological Life Sciences.
A novel active labeled metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Alternative Names: 4-[1-[4-[2- (Methylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenyl-d5 β-D-Glucopyranosiduronic Acid; (E/Z)-Endoxifen Glucuronide. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A labeled metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Alternative Names: E/Z Endoxifen-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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N-Desmethyl-4-hydroxy Tamoxifen (E/Z Mixture)
A metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Alternative Names: 4- [ (1E / Z) -1- [ [4- [2- (Methylamino) ethoxy] phenyl] phenylmethylene] propyl] phenol. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
A labeled metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Alternative Names: N-Demethyltamoxifen-ethyl-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
N-DesmethylTamoxifen HCl
One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Synonyms: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine Hydrochloride; N-Demethyltamoxifen Hydrochloride; N-DesmethylTamoxifen Hydrochloride. Grades: > 95%. CAS No. 15917-65-4. Molecular formula: C25H27NO.HCl. Mole weight: 393.96.
N-Desmethyltamoxifen hydrochloride
N-Desmethyltamoxifen hydrochloride. Group: Biochemicals. Alternative Names: (Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methylethanamine. Grades: Highly Purified. CAS No. 15917-65-4. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C25H28ClNO. US Biological Life Sciences.
Worldwide
N-Desmethyltamoxifen hydrochloride
N-Desmethyltamoxifen hydrochloride is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen hydrochloride is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 15917-65-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129099A.
A metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Alternative Names: N-Demethyltamoxifen, Hydrochloride(Z)-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N-methyl-ethanamine. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
A sulfhydryl reactive metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Alternative Names: Methanesulfonothioic Acid S- [2- [ [2- [4- (1, 2-diphenyl-1-buten-1-yl) phenoxy] ethyl] methylamino] ethyl] ester. Grades: Highly Purified. CAS No. 1025678-19-6. Pack Sizes: 1mg. US Biological Life Sciences.
A sulfhydryl reactive metabolite of the anti-cancer drug Tamoxifen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(Z)-4-Hydroxy-N-desmethyltamoxifen(contains up to 10% e isomer)
(Z)-4-Hydroxy-N-desmethylTamoxifen (contains up to 10% E isomer).
A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line. Group: Biochemicals. Alternative Names: 4-[ (1Z) -1-[4-[2- (Methylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol. Grades: Highly Purified. CAS No. 112093-28-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
(Z)-4-Hydroxy-N-DesmethylTamoxifen (Endoxifen)
Endoxifen, a significant metamolite of Tamoxifen, is a regulator of estrogen receptor and could be effective in the treatment of estrogen-dependent breast cancer. IC50: 1.6 μM. Uses: Endoxifen is a regulator of estrogen receptor and could be effective in the treatment of estrogen-dependent breast cancer. Synonyms: 4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol. Grades: >98 %. CAS No. 112093-28-4. Molecular formula: C25H27NO2. Mole weight: 373.49.
2-[4- (2-Bromo-1, 2-diphenylethenyl) phenoxy]-N-methyl-ethanamine is an intermediate in the synthesis of N-Desmethyl (E)-α-Hydroxy Tamoxifen which is a N-demethylated, α-Hydroxyated metabolite of Tamoxifen (T006000). Group: Biochemicals. Grades: Highly Purified. CAS No. 265321-58-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C23H22BrNO. US Biological Life Sciences.
Worldwide
(E/Z)-Endoxifen
One of the impurities of Tamoxifen, which is an estrogen response modifier as well as protein kinase C inhibitor. Synonyms: 4-Hydroxy-N-DesmethylTamoxifen; N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture); 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol. Grades: > 95%. CAS No. 110025-28-0. Molecular formula: C25H27NO2. Mole weight: 373.50.
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