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| Product | Description | |
|---|---|---|
| Desmosterol | Desmosterol is a cholesterol-like molecule. In the Bloch pathway of cholesterol biosynthesis, Desmosterol is a direct precursor of cholesterol. As an endogenous metabolite, Desmosterol is used to study cholesterol metabolism [1]. Desmosterol is an LXR activator and SREBP inhibitor, which can suppress macrophage inflammasome activation and prevent vascular inflammation and atherosclerosis. A reduction in Desmosterol promotes the production of mitochondrial reactive oxygen species ( ROS ) in macrophages and pyrin domain-dependent inflammasome activation of NLRP3. Desmosterol holds potential for research in inflammation, metabolism, and cardiovascular diseases [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 313-04-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113224. |  |
| Desmosterol-26,26,26,27,27,27-d6 | Steroids2H Labeled Compounds. Alternative Names: 24-dehydrocholesterol(d6); 5,24-cholestadien-3β-ol(d6). CAS No. 1246298-67-8. Molecular formula: C27H38OD6. Mole weight: 390.69. IUPACName: (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-7,7,7-trideuterio-6-(trideuteriomethyl)hept-5-en-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol. Catalog: ACM1246298678. |  |
| Desmosterol-d6 | Desmosterol-d 6 is the deuterium labeled Desmosterol. Desmosterol is a molecule similar to cholesterol. Desmosterol is the immediate precursor of cholesterol in the Bloch pathway of cholesterol biosynthesis. Desmosterol, as an endogenous metabolite, used to study cholesterol metabolism[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1246298-67-8. Pack Sizes: 500 μg; 1 mg. Product ID: HY-113224S. | |
| 3-O-tert-Butyldimethylsilyl 7-Dehydro Desmosterol-d6 | 3-O-tert-Butyldimethylsilyl 7-Dehydro Desmosterol-d6 is an intermediate in the preparation of 7-Dehydro Desmosterol-d6 (D229557). Group: Biochemicals. Alternative Names: (3 β)-3-O-tert-Butyldimethylsilyl-cholesta-5,7,24-trien-3-ol-d6; 3-O-tert-Butyldimethylsilyl-cholesta-5,7,24-trien-3 β-ol-d6; 3-O-tert-Butyldimethylsilyl-7-dehydrodesmosterol-d6; 3-O-tert-Butyldimethylsilyl-cholesta-5,7,24(25)-trien-3 β-ol-d6; 3-O-tert-Butyldimethylsilyl-cholesta-5,7,24-triene-3 β-ol-d6. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
| 7-Dehydro desmosterol | 7-Dehydro desmosterol. Group: Biochemicals. Alternative Names: (3b)-Cholesta-5,7,24-trien-3-ol; Cholesta-5,7,24-trien-3b-ol; 7-Dehydrodesmosterol. Grades: Highly Purified. CAS No. 1715-86-2. Pack Sizes: 5mg, 10mg. Molecular Formula: C27H42O. US Biological Life Sciences. | Worldwide |
| 7-Dehydro Desmosterol | 7-Dehydro Desmosterol is a precursor of Cholesterol. Synonyms: (3β)-Cholesta-5,7,24-trien-3-ol; Cholesta-5,7,24-trien-3β-ol; 7-Dehydrodesmosterol; Cholesta-5,7,24(25)-trien-3β-ol; Cholesta-5,7,24-triene-3β-ol. Grades: > 95%. CAS No. 1715-86-2. Molecular formula: C27H42O. Mole weight: 382.62. |  |
| 2-[(3 β)-Cholesta-5,24-dien-3-yloxy]tetrahydro-2H-pyran | 2-[(3 β)-Cholesta-5,24-dien-3-yloxy]tetrahydro-2H-pyran is an protected intermediate in the synthesis of Desmosterol (D296860), a metabolite of Cholesterol (C432501). Group: Biochemicals. Alternative Names: Cholestane, 2H-Pyran Deriv. Grades: Highly Purified. CAS No. 51231-31-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 27-Hydroxycholesterol | 27-Hydroxycholesterol, a desmosterol metabolite found in the brain , activates LXRα (EC50= 85 nM)and LXRβ (EC50= 71 nM) in vitro. 27-HC is also an estrogen receptor partial agonist. It suppresses β-estradiol-mediated breast cancer cell proliferation in vitro. Synonyms: cholest-(25R)-5-ene-3β,27-diol; (25R)-Cholest-5-ene-3β,26-diol; 27-OHC; 5,25R-Cholesten-3beta,26-diol; (25R)-26-Hydroxycholesterol. Grades: >99%. CAS No. 20380-11-4. Molecular formula: C27H46O2. Mole weight: 402.65. | |
| 3b-Cholesta-5,24-Dien-3-Ol | 3b-Cholesta-5,24-Dien-3-Ol. Group: Biochemicals. Alternative Names: Desmosterol. Grades: Highly Purified. CAS No. 313-04-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C27H44O. US Biological Life Sciences. | Worldwide |
| [[(3 β , 24E) -Cholesta-5, 24-dien-3-yl-26-13C]oxy] (1, 1-dimethylethyl) dimethylsilane-d6 | [[(3 β , 24E) -Cholesta-5, 24-dien-3-yl-26-13C]oxy] (1, 1-dimethylethyl) dimethylsilane is an protected intermediate in the synthesis of Desmosterol (D296860), a metabolite of Cholesterol (C432501). Group: Biochemicals. Alternative Names: Cholestane Silane Derivative-d6. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| (3 β, 5α, 8α)-5, 8-[N, N-(4-Phenylurazole)]-3-O-tert-butyldimethylsilyl-6-dehydro-desmostanol-d6 | (3 β, 5α, 8α)-5, 8-[N, N-(4-Phenylurazole)]-3-O-tert-butyldimethylsilyl-6-dehydro-desmostanol-d3 is an intermediate in the preparation of 7-Dehydro Desmosterol-d6 (D229557). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 5α,8α-[N,N-(4-Phenylurazole)]-3 β-O-tert-butyldimethylsilyloxy-chol-6-en-24-oic Acid Methyl Ester | 5α,8α-[N,N-(4-Phenylurazole)]-3 β-O-tert-butyldimethylsilyloxy-chol-6-en-24-oic Acid Methyl Ester is an intermediate in the preparation of 7-Dehydro Desmosterol-d6 (D229557). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 5α,8α-[N,N-(4-Phenylurazole)]-3-O-tert-butyldimethylsilyl-chol-6-en-24-al-3 β-ol | 5α,8α-[N,N-(4-Phenylurazole)]-3-O-tert-butyldimethylsilyl-chol-6-en-24-al-3 β-ol is an intermediate in the preparation of 7-Dehydro Desmosterol-d6 (D229557). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 5α,8α-[N,N-(4-Phenylurazole)]-3-O-tert-butyldimethylsilyl-chol-6-en-3 β,24-diol | 5α,8α-[N,N-(4-Phenylurazole)]-3-O-tert-butyldimethylsilyl-chol-6-en-3 β,24-diol is an intermediate in the preparation of 7-Dehydro Desmosterol-d6 (D229557). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Δ24-sterol reductase | Acts on a range of steroids with a 24(25)-double bond, including lanosterol, desmosterol and zymosterol. Group: Enzymes. Synonyms: lanosterol Δ24-reductase. Enzyme Commission Number: EC 1.3.1.72. CAS No. 9033-57-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1341; Δ24-sterol reductase; EC 1.3.1.72; 9033-57-2; lanosterol Δ24-reductase. Cat No: EXWM-1341. |  |
| fucosterol-epoxide lyase | The insect enzyme is involved in the conversion of sitosterol into cholesterol. Group: Enzymes. Synonyms: (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase; (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming). Enzyme Commission Number: EC 4.1.2.33. CAS No. 99676-42-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4870; fucosterol-epoxide lyase; EC 4.1.2.33; 99676-42-3; (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase; (24R,24'R)-fucosterol-epoxide acetaldehyde-lyase (desmosterol-forming). Cat No: EXWM-4870. | |
| sterol 24-C-methyltransferase | Requires glutathione. Acts on a range of sterols with a 24(25)-double bond in the sidechain. While zymosterol is the preferred substrate it also acts on desmosterol, 5α-cholesta-7,24-dien-3β-ol, 5α-cholesta-5,7,24-trien-3β-ol, 4α-methylzymosterol and others. S-Adenosyl-L-methionine attacks the Si-face of the 24(25) double bond and the C-24 hydrogen is transferred to C-25 on the Re face of the double bond. Group: Enzymes. Synonyms: Δ24-methyltransferase; Δ24-sterol methyltransferase; zymosterol-24-methyltransferase; S-adenosyl-4-methionine:sterol Δ24-methyltransferase; SMT1; 24-sterol C-methyltransferase; S-adenosyl-L-methionine:Δ24(23)-sterol methyltransferase; phytosterol methyltransferase. Enzyme Commission Number: EC 2.1.1.41. CAS No. 37257-07-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1945; sterol 24-C-methyltransferase; EC 2.1.1.41; 37257-07-1; Δ24-methyltransferase; Δ24-sterol methyltransferase; zymosterol-24-methyltransferase; S-adenosyl-4-methionine:sterol Δ24-methyltransferase; SMT1; 24-sterol C-methyltransferase; S-adenosyl-L-methionine:Δ24(23)-sterol methyltransferase; phytosterol methyltransferase. Cat No: EXWM-1945. | |
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