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2-tert-Butyldimethylsilyloxy-1,1-dimethylethylamine is an intermediate in the synthesis of Timolol (T443705), an antihypertensive agent. Group: Biochemicals. Alternative Names: 1- [ [tert-Butyldimethylsilyl] oxy] -2-methylpropan-2-amine; 1-[[ (1, 1-Dimethylethyl) dimethylsilyl]oxy]-2-methyl-2-propanamine. Grades: Highly Purified. CAS No. 117460-98-7. Pack Sizes: 1g. US Biological Life Sciences.
3-(4-(2-Butyl-1-(4-(4-chlorophenoxy)phenyl)-1H-imidazol-4-yl)phenoxy)-N,N-diethylpropan-1-amine Hyrochloride acts as a reagent in the preparation of imidazoles for the treatment of RAGE-mediated diseases and pharmacokinetics. Group: Biochemicals. Grades: Highly Purified. CAS No. 1284150-65-7. Pack Sizes: 5mg, 10mg. Molecular Formula: C32H38ClN3O2; 2(HCl), Molecular Weight: 532.122364599999. US Biological Life Sciences.
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3-(Di-t-butylphosphino)propylamine,min. 97%(10 wt% in thf)
A Boc protected bifunctional iron chelating agent that has be. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
9- ( (2R, 4S, 5R) -4- ( (tert-Butyldimethylsilyl) oxy) -5- ( ( (tert-butyldimethylsilyl) oxy) methyl) tetrahydrofuran-2-yl) -9H-purin-6-amine is a complex and multi-faceted compound that has found application in the research of purine metabolism as well as in the development of cancer treatments. Its capacity to impede cancer cell growth and proliferation via the manipulation of specific purine pathways is well documented. Moreover, studies have shown that it possesses immense potential in the treatment of neurodegenerative diseases such as Alzheimer's and Parkinson's. Synonyms: Adenosine, 2'-deoxy-3',5'-bis-O-[(1,1-dimethylethyl)dimethylsilyl]-;3',5'-Bis-O-TBDMS-2'-Deoxyadenosine;3',5'-Bis-O-(tert-butyldimethylsilyl)-deoxyadenosine; 3',5'-Bis-O-(tert-butyldimethylsi lyl)-deoxyadenosine; 3',5'-O-Bis(tert-butyldimethylsilyl)-2'-deoxyadenosine; 3',5'-O-bis(tert-butyldimethylsiyl)-2'-deoxy-adenosine; 9-[ (2R, 4S, 5R)-4-[tert-butyl (dimethyl)silyl]oxy-5-[[tert-butyl (dimethyl)silyl]oxymethyl]oxolan-2-yl]purin-6-amine. Grades: 98%. CAS No. 51549-32-7. Molecular formula: C22H41N5O3Si2. Mole weight: 479.76.
Bis[2-(dibutylamino)ethyl]amine
Heterocyclic Organic Compound. Alternative Names: BIS[2-(DIBUTYLAMINO)ETHYL]AMINE; BIS[2-(DI-N-BUTYLAMINO)ETHYL]AMINE; N, N, N'', N''-TETRA-N-BUTYLDIETHYLENETRIAMINE; N, N, N', N'-TETRA-N-BUTYLDIETHYLENETRIAMINE; N, N, N'', N''-TETRABUTYLDIETHYLENETRIAMINE. CAS No. 100173-92-0. Molecular formula: C20H45N3. Mole weight: 327.59. Purity: 0.96. IUPACName: N,N-dibutyl-N-[2-(dibutylamino)ethyl]ethane-1,2-diamine. Canonical SMILES: CCCCN(CCCC)CCNCCN(CCCC)CCCC. Density: 0.84. Catalog: ACM100173920.
Butyl-(2,4-dimethoxy-phenyl)-amine
Heterocyclic Organic Compound. Alternative Names: BUTYL-(2,4-DIMETHOXY-PHENYL)-AMINE. CAS No. 124006-23-1. Molecular formula: C12H19NO2. Mole weight: 209.28476. Catalog: ACM124006231.
Cyanine 3 Monofunctional Hexanoic Acid Dye n-tert-Butyl oxycarbonyl ethyl ene diamine Amide Potassium Salt
A water soluble fluorescent dye with an accessable amine linker. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
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Dichloro[(4S,5S)-(+)-4,5-bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane][(S)-(-)-2-(i-butyl)methanamine)-1H-benzimidazole]ruthenium(II), min. 95%
Efficient ruthenium catalyst for asymmetric hydrogenation of aryl ketones. Group: Ruthenium catalysts. Alternative Names: MFCD16038132; 1574321-76-8; Dichloro[(4S, 5S)-(+)-4, 5-bis(diphenylphosphinomethyl)-2, 2-dimethyl-1, 3-dioxolane][(S)-(-)-2-(i-butyl)methanamine)-1H-benzimidazole]ruthenium(II). CAS No. 1574321-76-8. Molecular formula: C43H49Cl2N3O2P2Ru. Mole weight: 873.802g/mol. IUPACName: (1S)-1-(1H-benzimidazol-2-yl)-3-methylbutan-1-amine;dichlororuthenium;[(4S,5S)-5-(diphenylphosphanylmethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl-diphenylphosphane. Canonical SMILES: CC (C)CC (C1=NC2=CC=CC=C2N1)N. CC1 (OC (C (O1)CP (C2=CC=CC=C2)C3=CC=CC=C3)CP (C4=CC=CC=C4)C5=CC=CC=C5)C. Cl[Ru]Cl. Catalog: ACM1574321768.
Dichloro[(4S,5S)-(+)-4,5-bis(diphenylphosphinomethyl)-2,2-dimethyl-1,3-dioxolane][(S)-(-)-2-(t-butyl)methanamine)-1H-benzimidazole]ruthenium(II), min. 97%
Efficient ruthenium catalyst for asymmetric hydrogenation of aryl ketones. Group: Ruthenium catalysts. Alternative Names: MFCD16038133; 1443051-98-6; Dichloro[(4S, 5S)-(+)-4, 5-bis(diphenylphosphinomethyl)-2, 2-dimethyl-1, 3-dioxolane][(S)-(-)-2-(t-butyl)methanamine)-1H-benzimidazole]ruthenium(II). CAS No. 1443051-98-6. Molecular formula: C43H49Cl2N3O2P2Ru. Mole weight: 873.802g/mol. IUPACName: (1S)-1-(1H-benzimidazol-2-yl)-2,2-dimethylpropan-1-amine;dichlororuthenium;[(4S,5S)-5-(diphenylphosphanylmethyl)-2,2-dimethyl-1,3-dioxolan-4-yl]methyl-diphenylphosphane. Canonical SMILES: CC1 (OC (C (O1)CP (C2=CC=CC=C2)C3=CC=CC=C3)CP (C4=CC=CC=C4)C5=CC=CC=C5)C. CC (C) (C)C (C1=NC2=CC=CC=C2N1)N. Cl[Ru]Cl. Catalog: ACM1443051986.
Diethylene triaminetriacetic Acid Trifluoroacetamide Tri(tert-butyl Ester). Group: Biochemicals. Alternative Names: Di-tert-butyl 3-[(tert-Butoxycarbonyl)methyl]-6-(trifluoroacetyl)amino-3,6-diazaoctanedionate. Grades: Highly Purified. CAS No. 180152-84-5. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Focal Adhesion Kinase Inhibitor III (FAK Inhibitor III, N-(4-tert-Butylbenzyl)-1,5-dimethyl-1,5-dihydropyrazolo[4,3-c][2,1]benzothiazin-8-amine-4,4-dioxide)
A cell-permeable pyrazolobenzothiazined ioxide compound that targets and locks FAK in its inactive conformation, resulting in preincubation time-dependent inhibition in kinase assays and FAK autophosphorylation in human prostate cancer PC3M-luc cells (IC50 = 7.1uM with 30 min inhibitor preincubation), while exhibiting little activity toward Akt1, Aurora B, HER2, MEK1, p38alpha, Pyk2, or Src even at concentrations as high as 10uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
N-Benzyloxycarbonyl-L-aspartic Acid β-tert-Butyl Ester Dicyclohexylamine Salt
Protected amino acid. Group: Biochemicals. Alternative Names: N-Carbobenzoxy-L-aspartic Acid β-tert-Butyl Ester Dicyclohexylamine Salt. Grades: Highly Purified. CAS No. 23632-70-4. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
N,N'-Di-sec-butyl-p-phenylenediamine
N,n'-di-sec-butyl-p-phenylenediamine appears as amber to red or dark reddish black liquid. (NTP, 1992);Liquid. Group: Amines. Alternative Names: Antioxidant 22. CAS No. 101-96-2. Molecular formula: C14H24N2. Mole weight: 220.35. Purity: 98%+. IUPACName: 1-N,4-N-Di(butan-2-yl)benzene-1,4-diamine. Canonical SMILES: CCC(C)NC1=CC=C(C=C1)NC(C)CC. Density: 0.942 g/mL. ECNumber: 202-992-2. Catalog: ACM101962-1.
N-Nitrosodiisobutylamine-d4
Labeled N-Nitrosodiisobutylamine. N-Nitrosodiisobutylamine is a nitrosoamine compound. Group: Biochemicals. Alternative Names: 2-Methyl-N-(2-methylpropyl)-N-nitroso-1-propanamine-d4; 2,2'-Dimethyl-N-nitrosodipropylamine-d4; Diisobutylnitrosamine-d4; Diisobutylnitrosoamine-d4; N,N-Diisobutylnitrosamine-d4; N-Nitroso-di-iso-butylamine-d4; NSC 134-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
N-Nitroso-di-(N-butyl-d9)amine
Heterocyclic Organic Compound. CAS No. 1219798-82-9. Molecular formula: 176.35. Purity: 98 atom % D. Catalog: ACM1219798829.
PP1 Analog V, 2,3-DMB-PP1 (4-Amino-1-tert-butyl-3- (2, 3-dimethylbenzyl) pyrazolo[3, 4-d]pyrimidine, 1-tert-Butyl-3-(2,3-dimethylbenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Syk ASKA Inhibitor II, PDK1 ASKA Inhibitor)
A cell-permeable 3-MB-PP1 analog that is more effective than 3-MB-PP1 in inhibiting SykM442A S505A ASKA- (analog-sensitive kinase alleles) mediated cellular calcium flux (98% vs. 20% inhibition, respectively, by 1uM 2,3-DMB-PP1 or 3-MB-PP1) in Syk MASA-expressing DT40 cells. Also shown to selectively inhibit L159G ASKA, but not wt, PDK1-dependent GSK3&alpha Ser21 and S6 Ser235/236 phosphorylation upon IGF1 stimulation in mES cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 956026-24-7. Pack Sizes: 10mg. US Biological Life Sciences.
10-DEBC hydrochloride is a selective and reversible Akt/PKB inhibitor suppressing the IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), and inhibiting downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. 10-DEBC hydrochloride inhibits cell growth (IC50 ~ 2-6 μM) and leads to apoptosis in rhabdomyosarcoma cells. Synonyms: 10H-Phenoxazine-10-butanamine, 2-chloro-N,N-diethyl-, hydrochloride (1:1); Akt Inhibitor X; 2-Chloro-N,N-diethyl-10H-phenoxazine-10-butanamine hydrochloride; 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride; 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride. Grades: ≥99% by HPLC. CAS No. 925681-41-0. Molecular formula: C20H25N2OCl.HCl. Mole weight: 381.34.
1,1-Dimethylethyl Nitrite
ert-Butyl nitrite is an intermediate used for diazotization and nitrosation of alcohols, thiols, amines and cycloalkanes. It is also used to prepare aryl azides from aryl amines. Group: Biochemicals. Grades: Highly Purified. CAS No. 540-80-7. Pack Sizes: 1g, 10g. Molecular Formula: C4H9NO2. US Biological Life Sciences.
1,5,8,12-Tetrakis[4,6-bis(N-butyl-N-1,2,2,6,6-pentamethyl-4-piperidylamino)-1,3,5-triazin-2-yl]-1,5,8,12-tetraazadodecane is used as a light/thermal stabilizer in olefin polymers intended for use in contact with food. Group: Biochemicals. Alternative Names: N,N-1,2-ethanediylbis[N-[3-[[4,6-bis[butyl(1,2,2,6,6-pentamethyl-4-piperidinyl)amino]-1,3,5-triazin-2-yl]amino]propyl]-N',N-dibutyl-N',N-bis(1,2,2,6,6-pentamethyl-4-piperidinyl)- 1,3,5-Triazine-2,4,6-triamine; Antioxidant 119; Chimassorb 119; Chimassorb 119FL; Chimassorb NOR 119; HALS 11; Lowilite 19; Tinuvin 119. Grades: Highly Purified. CAS No. 106990-43-6. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
1-Naphthyl PP1 hydrochloride
1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases, including v-Src and c-Fyn, tyrosine kinase c-Abl and CAMK II with IC50 values of 1.0, 0.6, 0.6, 18 and 22 μM for v-Src, c-Fyn, c-Abl, CDK2 and CAMK II respectively. It was considerably more potent and showed distinct substituent effects at the pyrazolopyrimidine core. It was cell-active, and potently blocked prostate cancer cell proliferation by inducing G2/M arrest. Uses: 1-naphthyl pp1 hydrochloride could potently block prostate cancer cell proliferation by inducing g2/m arrest. Synonyms: 1-Tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyriMidin-4-aMine hydrochloride;1-NA-PP 1 hydrochloride. Grades: >98 %. CAS No. 956025-47-1. Molecular formula: C19H20ClN5. Mole weight: 353.85.
2-(Boc-amino)ethanthiol (CAS# 67385-09-5) is used in the synthesis of several organic compounds including a novel, anisamide-targeted cyclodextrin nanoformulation for the delivery of siRNA to prostate cancer cells which is a potential therapeutic option. Also used in the synthesis of bifunctional azobenzene glycoconjugates for cysteine-based photosensitive cross-linking with bioactive peptides. Synonyms: (2-Mercaptoethyl)carbamic Acid 1,1-Dimethylethyl Ester; (2-Mercaptoethyl)carbamic acid tert-butyl ester; 1,1-Dimethylethyl (2-mercaptoethyl)carbamate; 2-(N-tert-Butoxycarbonylamino)ethanethiol; 2-(tert-Butoxycarbonylamino)ethanethiol; 2-(tert-Butoxycarbonylamino)ethylmercaptan; 2-[(tert-Butoxycarbonyl)amino]-1-ethanethiol; 2-tert-Butylcarbamate-ethanethiol; N-Boc-2-aminoethanethiol; N-tert-Butoxycarbonyl-2-aminoethanethiol; N-tert-Butoxycarbonylcysteamine; tert-Butyl (2-mercaptoethyl)carbamate; tert-Butyl (2-sulfanylethyl)carbamate; tert-Butyl-N-(2-mercaptoethyl)carbamate. Grades: 90 %. CAS No. 67385-09-5. Molecular formula: C7H15NO2S. Mole weight: 177.26.
Ligand used in the Pd-catalyzed Suzuki coupling and animation of unactivated aryl chlorides. The reactions generally occur at room temperature and give high yields of product. Ligand used in Pd-catalyzed C-N bond formation. A general synthesis of N6-aryl-2'deoxyadenosine analogues. Ligand used in Pd-catalyzed N-arylation of indoles. Ligand used in Pd-catalyzed synthesis of aryl-tert-butyl ethers. Effective ligand in the Pd-catalyzed arylation of ester enolates. Ligand employed in arylation of ketone enolates using ortho-halo nitrobenezenes. Ligand employed in the amination of aryl nonaflates using Pd catalysts. Ligand used for cascade alkenyl amination/Heck reaction for the synthesis of indoles. Ligand used in Pd-catalyzed Kumada-Corriu cross coupling at low temperatures. Ligand used in Rh-catalyzed intramolecular hydroamination of unactivated terminal and internal alkenes with primary and secondary amines. Ligand used in Au-catalyzed cycloisomerization of allenes. Group: Organic phosphine compounds. Alternative Names: 2-di-cyclohexylphosphino-2'-(N,N-dimethylamino)biphenyl; 118492-EP2272832A1; (2'-dicyclohexylphosphanyl-biphenyl-2-yl)dimethyl-amine; 2-(Dicyclohexylphosphino)-2'-(N,N-diMethylaMino)biphenyl, 98% DavePhos; (2'-dicyclohexylphosphanyl -biphenyl-2-yl)-dimethyl-amine; Buchwald phosphine ligands, davephos phosphine ligand-; 2-dicyclohexylphosphino-2'-(N,N'-dimethylamino)biphe
2-(Di-tert-butylphosphino)biphenyl
Ligand used in the palladium-catalyzed synthesis of aromatic amines from aryl chlorides, bromides and triflates. Ligand employed in a very active and general catalyst for Suzuki coupling reactions using aryl chlorides, bromides and triflates. Ligand used in palladium-catalyzed synthesis of oxindoles from α-chloroacetanilides. Effective ligand used in palladium-catalyzed arylation of thiazoles. Used in the formation of 2-benzylindolines via sequential palladium-catalyzed N-arylation/cyclization/C-arylation. Selective in the palladium-catalyzed arylation of silyl enol ethers formed from copper-catalyzed reduction of enones. Group: Organic phosphine compounds. Alternative Names: (2-Biphenylyl)-Di-Tert-Butylphosphine. CAS No. 224311-51-7. Molecular formula: C20H27P. Mole weight: 298.4. Appearance: Solid. Purity: 0.98. IUPACName: ditert-butyl-(2-phenylphenyl)phosphane. Canonical SMILES: CC (C) (C)P (C1=CC=CC=C1C2=CC=CC=C2)C (C) (C)C. Density: 1 g/cm3. Catalog: ACM224311517-1.
[2- (Di-tert-butylphosphinomethyl) -6- (diethylaminomethyl) pyridine] carbonylchlorohydridoruthenium (II)
Ruthenium catalyst for the direct synthesis of amides from alcohols and primary amines. Ruthenium catalyst for the hydrogenation of esters in high yields under mild pressure and neutral conditions. Ruthenium catalyst for the dehydrogenative coupling of alcohols to form esters in high yields under neutral conditions. Ruthenium catalyst for the synthesis of amides from esters and amines with liberation of hydrogen gas. Ruthenium catalyst for the hydrogenation of 3-methyl-2-oxalidinone. Group: Ruthenium series catalysts. Alternative Names: Carbonylchlorohydrido[6- (di-t-butylphosphinomethyl)-2- (N, N-diethylaminomethyl)pyridine]ruthenium (II); 863971-62-4. CAS No. 863971-62-4. Molecular formula: C20H37ClN2OPRu. Mole weight: 489.023g/mol. IUPACName: chlororuthenium;N-[[6-(ditert-butylphosphanylmethyl)pyridin-2-yl]methyl]-N-ethylethanamine;formaldehyde. Canonical SMILES: CCN (CC)CC1=NC (=CC=C1)CP (C (C) (C)C)C (C) (C)C. C=O. Cl[Ru]. Catalog: ACM863971624.