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| Product | Description | |
|---|---|---|
| 2,4-Diaminopyrimidine | 2,4-Diaminopyrimidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 156-81-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C4H6N4. US Biological Life Sciences. |  Worldwide |
| 2,4-Diaminopyrimidine | 2,4-Diaminopyrimidine. Uses: Designed for use in research and industrial production. Product Category: Pyrimidines. Appearance: White to Yellow Powder or Crystal or Chunk(s). CAS No. 156-81-0. Molecular formula: C4H6N4. Mole weight: 110.12. Purity: 0.98. Product ID: ACM156810. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2,4-Diaminopyrimidine 3-N-Oxide | 2,4-Diaminopyrimidine 3-N-Oxide is a useful organic synthetic reagent for the preparation of pyrimidines and in the making of hair loss and skin care compositions. Group: Biochemicals. Grades: Highly Purified. CAS No. 74638-76-9. Pack Sizes: 250mg, 1g. Molecular Formula: C4H6N4O, Molecular Weight: 126.12. US Biological Life Sciences. | Worldwide |
| 2,4-diaminopyrimidine 3-oxide | 2,4-diaminopyrimidine 3-oxide. Uses: Designed for use in research and industrial production. CAS No. 74638-76-9. Molecular formula: C4H6N4O. Mole weight: 126.12. Purity: 0.99. Product ID: ACM74638769. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2,4-Diaminopyrimidine-5-carbaldehyde ≥95% | 2,4-Diaminopyrimidine-5-carbaldehyde ≥95%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| 2,4-Diaminopyrimidine-5-carbonitrile | Intermediate for the preparation of medicines and agrochemicals. Group: Biochemicals. Alternative Names: 2,4-Diamino-5-cyanopyrimidine; 2, 4-Diamino-5-pyrimidinecarbonitri le; NSC 135235. Grades: Highly Purified. CAS No. 16462-27-4. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2,4-Diaminopyrimidine-5-carbonitrile ≥95% | 2,4-Diaminopyrimidine-5-carbonitrile ≥95%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| 2,4-Diaminopyrimidine-5-carboxaldehyde | Intermediate for the preparation of medicines and agrochemicals. Group: Biochemicals. Alternative Names: 2, 4-Diamino-5-pyrimidinecarboxalde hyde; 2, 6-Diamino-5-pyrimidinecarboxalde hyde; NSC 211353. Grades: Highly Purified. CAS No. 20781-06-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2,5-Diaminopyrimidine (2-aminopyrimidin-5-yl)amine) | 2,5-Diaminopyrimidine (2-aminopyrimidin-5-yl)amine). CAS No: 22715-27-1 |  Sarchem Laboratories New Jersey NJ |
| 2-Chloro-4,5-diaminopyrimidine | 2-Chloro-4,5-diaminopyrimidine. CAS No: 14631-08-4 | Sarchem Laboratories New Jersey NJ |
| 2-Chloro-4,5-diaminopyrimidine | 2-Chloro-4,5-diaminopyrimidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 14631-08-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C4H5ClN4. US Biological Life Sciences. | Worldwide |
| 4,5-Diaminopyrimidine | 4,5-Diaminopyrimidine. CAS No: 13754-19-3 | Sarchem Laboratories New Jersey NJ |
| 4,5-Diaminopyrimidine | 4,5-Diaminopyrimidine is an intermediate in the synthesis of Nisin, a compound that was first introduced as a good preservative and was later on discovered to have antibacterial activity against gram positive bacteria. 4,5-Diaminopyrimidine is also used as a reagent to synthesize uracil-based 2-aminoanilide derivatives, compounds that act as histone deacetylase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 13754-19-3. Pack Sizes: 1g, 5g. Molecular Formula: C4H6N4, Molecular Weight: 110.12. US Biological Life Sciences. | Worldwide |
| 4,5-Diaminopyrimidine | 4,5-Diaminopyrimidine. Uses: Designed for use in research and industrial production. Product Category: Pyrimidines. Appearance: White to Yellow to Tan Powder. CAS No. 13754-19-3. Molecular formula: C4H6N4. Mole weight: 110.12. Purity: 0.95. Product ID: ACM13754193. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4,6-Diaminopyrimidine | 4,6-Diaminopyrimidine. Group: Biochemicals. Alternative Names: 4,6-Pyrimidinediamine; NSC 211429. Grades: Highly Purified. CAS No. 2434-56-2. Pack Sizes: 2.5g. Molecular Formula: C4H6N4, Molecular Weight: 110.12. US Biological Life Sciences. | Worldwide |
| 4,6-Diaminopyrimidine hemisulfate 1-hydrate | 4,6-Diaminopyrimidine hemisulfate 1-hydrate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,6-DIAMINOPYRIMIDINE HEMISULFATE, MONOHYDRATE, 98;pyrimidine-4,6-diammonium hydrogen sulphate (1:2);4,6-DIAMINOPYRIMIDINE HEMISULFATE MONO- HYDRATE 98%;4,6-Pyrimidinediamine hemisulfate. Product Category: Heterocyclic Organic Compound. CAS No. 77709-02-5. Molecular formula: C4H8N4O. Mole weight: 336.331. Product ID: ACM77709025. Alfa Chemistry ISO 9001:2015 Certified. Categories: 207226-28-6. | |
| 4-Chloro-2,6-diaminopyrimidine | 4-Chloro-2,6-diaminopyrimidine. Group: Biochemicals. Alternative Names: 6-chloro-2,4-diamino-pyrimidine. Grades: Highly Purified. CAS No. 156-83-2. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C4H5ClN4. US Biological Life Sciences. | Worldwide |
| 4-Chloro-2,6-diaminopyrimidine 99+% (HPLC) | 4-Chloro-2,6-diaminopyrimidine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| 6-Chloro-pyrimidine-2,4-diamine (6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine) | 6-Chloro-pyrimidine-2,4-diamine (6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine). Group: Biochemicals. Alternative Names: 6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Pyrrolidinyl diaminopyrimidine oxide | Pyrrolidinyl diaminopyrimidine oxide is a profoundly intricate compound that has exhibited excellent potential for drug development to tackle inflammation and cancer. By selectively blocking protein kinases responsible for cell proliferation and survival, it provides a vast scope for treating multiple ailments. Clinically, Pyrrolidinyl diaminopyrimidine oxide delivers remarkable results in suppressing an array of tumors and inflammation-triggering conditions of varying severity. Synonyms: 2,6-diamino-4-(pyrrolidin-1-yl)pyrimidine 1-oxide; Triaminodil. Grades: 97%. CAS No. 55921-65-8. Molecular formula: C8H13N5O. Mole weight: 195.22. |  |
| 1-Methanesulfonyl-2-morpholino-4-nitrobenzene | 1-Methanesulfonyl-2-morpholino-4-nitrobenzene acts as a reagent for the preparation of diaminopyrimidinecarbo xamide derivatives as SYK kinase inhibitors useful in treatment and prevention of SYK kinase-mediated diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1194974-72-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H14N2O5S, Molecular Weight: 286.3. US Biological Life Sciences. | Worldwide |
| 1-Methyl-4-(4-nitrophenyl)piperazine | 1-methyl-4-(4-nitrophenyl)piperazine was a reagent in the preparation of diaminopyrimidines as reversible and irreversible inhibitors of mutant EGFR tyrosine kinases for treatment of non-small-cell lung cancer. It was also used in the prepn. of disubstituted pyrimidine compds. as EGFR or/and ALK inhibitors useful in the treatment of diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 16155-03-6. Pack Sizes: 500mg, 1g. Molecular Formula: C11H15N3O2, Molecular Weight: 221.26. US Biological Life Sciences. | Worldwide |
| 2, 4-Bis (benzylamino) pyrimidine | 2, 4-Bis (benzylamino) pyrimidine is an intermediate in the synthesis of pro-apoptotic agents based on 2,4-diaminoquinazoline, 2,4-diaminopyrido[2,3-d]pyrimidine and 2,4-diaminopyrimidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 65448-40-0. Pack Sizes: 250mg, 500mg. Molecular Formula: C18H18N4. US Biological Life Sciences. | Worldwide |
| 2,4-Diamino-6-hydroxypyrimidine | 2,4-Diamino-6-hydroxypyrimidine has been found to be a GCH1 inhibitor and could suppress the activity of NO synthase through preventing the synthesis of BH4. Uses: Enzyme inhibitors. Synonyms: 2,6-Diamino-4(1H)-pyrimidinone; 2,6-Diaminopyrimidin-4-one; 6-Aminoisocytosine; NSC 44914; NSC 680818; NSC 9302; 4(3H)-Pyrimidinone, 2,6-diamino-; 2,6-Diamino-4(3H)-pyrimidinone; 4(1H)-Pyrimidinone, 2,6-diamino-; 2,4-Diamino-6-pyrimidinone; 2,6-Diamino-1,4-dihydropyrimidin-4-one; 2,6-Diamino-1H-pyrimidin-4-one; 2,6-Diamino-3,4-dihydropyrimidin-4-one; 2,6-Diamino-3H-pyrimidin-4-one; 2,6-Diamino-4-pyrimidinol; 4-Hydroxypyrimidine-2,6-diamine; 6-Hydroxy-2,4-diaminopyrimidine; 6-Hydroxy-2,4-pyrimidinediamine. Grades: ≥95%. CAS No. 56-06-4. Molecular formula: C4H6N4O. Mole weight: 126.12. | |
| 2, 4-Dichloro-6-trifluoro methyl pyrimidine | 2, 4-Dichloro-6-trifluoro methyl pyrimidine is a useful synthetic intermediate. It can be used to synthesize 2,4-diaminopyrimidines derivatives that show antiplasmodial activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 16097-64-6. Pack Sizes: 1g, 2.5g. Molecular Formula: C5HCl2F3N2, Molecular Weight: 216.98. US Biological Life Sciences. | Worldwide |
| 2,6-Diamino-4-chloropyrimidine | 2,6-Diamino-4-chloropyrimidine. Uses: Designed for use in research and industrial production. Product Category: Pyrimidines. Appearance: White to Tan Powder or Crystals. CAS No. 156-83-2. Molecular formula: C4H5ClN4. Mole weight: 144.56. Purity: 0.98. Product ID: ACM156832. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4-Chloro-2,6-diaminopyrimidine. | |
| 2,6-Diamino-4-chloropyrimidine 1-oxide | 2,6-Diamino-4-chloropyrimidine 1-oxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TIMTEC-BB SBB003960;2,4-PYRIMIDINEDIAMINE, 6-CHLORO-, 3-OXIDE;2,6-DIAMINO-4-CHLOROPYRIMIDINE 1-OXIDE;6-CHLORO-3-OXY-PYRIMIDINE-2,4-DIAMINE;4-Chloro-2,6-Diaminopyrimidine-N-Oxide;6-Chloro-2,4-diaminopyrimidine-N-oxide;2,4-DIAMINO-6-CHLORO PYRIMIDINE 97.0%. Product Category: Polymer/Macromolecule. CAS No. 35139-67-4. Molecular formula: C4H5ClN4O. Mole weight: 160.56. Product ID: ACM35139674. Alfa Chemistry ISO 9001:2015 Certified. Categories: 34960-71-9. | |
| 2,6-Diamino-4-pyrimidinyl p-Toluenesulfonate 3-Oxide | 2,6-Diamino-4-pyrimidinyl p-Toluenesulfonate 3-Oxide. Group: Biochemicals. Alternative Names: 2,6-Diamino-4-pyrimidinol 4- (4-Methyl Benzene sulfonate) 1-Oxide; 6-Tosyloxy-2,4-diaminopyrimidine 3-Oxide. Grades: Highly Purified. CAS No. 75105-16-7. Pack Sizes: 100mg. Molecular Formula: C11H12N4O4S, Molecular Weight: 296.3. US Biological Life Sciences. | Worldwide |
| 2-Iodoanisole | 2-Iodoanisole is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 529-28-2. Pack Sizes: 10g, 25g. Molecular Formula: C7H7IO, Molecular Weight: 234.03. US Biological Life Sciences. | Worldwide |
| 2-?Nitrophenethylamine Hydrochloride | 2-?Nitrophenethylamine Hydrochloride is used in preparation of diaminopyrimidines as MTH-1 inhibitors for treament of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 861337-74-8. Pack Sizes: 500mg, 1g. Molecular Formula: C8H10N2O2; HCl, Molecular Weight: 166.183646. US Biological Life Sciences. | Worldwide |
| 4,6-Diamino-2-mercaptopyrimidine | 4,6-Diamino-2-mercaptopyrimidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Mercapto-4,6-diaminopyrimidine, 4,6-Diamino-2-thiopyrimidine, 4,6-Diamino-2-mercaptopyrimidine, 2(1H)-Pyrimidinethione, 4,6-diamino-, 4,6-Diaminopyrimidine-2-thiol, NSC1586, NSC680831, AIDS023077, AIDS-023077, NSC 1586, EINECS 213-721-2, SBB004143, SBB007564, ZINC00967453, ZINC04284766, 4,6-diaminopyrimidine-2(3H)-thione, NSC 680831, AI3-52092, AG-670/32486009, 1004-39-3. Product Category: Heterocyclic Organic Compound. Appearance: Brown-Grey Solid. CAS No. 1004-39-3. Molecular formula: C4H6N4S. Mole weight: 142.18. Purity: N/A. IUPACName: 4,6-diamino-1H-pyrimidine-2-thione. Canonical SMILES: C1=C(NC(=S)N=C1N)N. Density: 1.78 g/cm³. ECNumber: 213-721-2. Product ID: ACM1004393. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-Desmethoxy-4-bromo Trimethoprim | An impurity of Trimethoprim with inhibitory effects on the enzyme dihydrofolate reductase. Group: Biochemicals. Alternative Names: 5-[ (3-Bromo-4, 5-dimethoxyphenyl) methyl]-2, 4-diaminopyrimidine; 2, 4-Diamino-5- (5-bromoveratryl) pyrimidine; 2, 4-Diamino-5- (3, 4-dimethoxy-5-bromobenzyl) pyrimidine; 2, 4-Diamino-5- (3-bromo-4, 5-dimethoxybenzyl) pyrimidine; 5-(3'-Bromo-4',5'-dimethoxybenzyl)-2,4-diaminopyrimidine. Grades: Highly Purified. CAS No. 16285-82-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 5,6-Diaminouracil | 5,6-Diaminouracil (CAS# 3240-72-0) is a useful research chemical. Synonyms: 5,6-Diamino-2,4-dihydroxypyrimidine; 4,5-Diaminouracil; 5,6-diamino-1H-pyrimidine-2,4-dione; 2,4(1H,3H)-Pyrimidinedione, 5,6-diamino-, monohydrochloride; 5,6-DIAMINOURACIL MONOHYDROCHLORIDE; 5,6-diaminopyrimidine-2,4(1H,3H)-dione; 4,5-DIAMINOURACIL,HYDROCHLORIDE SALT. Grades: ≥ 95 %. CAS No. 3240-72-0. Molecular formula: C4H7ClN4O2. Mole weight: 178.58. | |
| 6-Aminoquinoline | 6-Aminoquinoline is used in the preparation of diaminopyrimidine derivatives as 5-HT4 receptor agonists. Group: Biochemicals. Alternative Names: (Quinolin-6-yl)amine; 6-Quinolylamine; NSC 58388. Grades: Highly Purified. CAS No. 580-15-4. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 6-Ethyl-5-(4-nitrophenyl)-2,4-pyrimidinediamine | A diaminopyrimidine derivative with antimalarial and antibacterial properties. Group: Biochemicals. Alternative Names: 2,4-Diamino-6-ethyl-5-(p-nitrophenyl)-pyrimidine; NSC 372954. Grades: Highly Purified. CAS No. 71552-34-6. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| α-(1-Methoxypropylidene)-4-nitro-benzeneacetonitrile | Used in the preparation of 2,4-diaminopyrimidine growth hormone secretagogue receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 885428-60-4. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| AR709 | AR709 is a novel diaminopyrimidine antibiotic. It is currently in development for treatment of community-acquired upper and lower respiratory tract infections. It showed excellent activity against both drug-susceptible and multidrug-resistant pneumococci. Uses: Ar709 is currently in development for treatment of community-acquired upper and lower respiratory tract infections. Synonyms: AR-709; AR 709; 1H-Indole-2-carboxamide, 5-chloro-3-((4-((2,4-diamino-5-pyrimidinyl)methyl)-6,7-dimethoxy-2-benzofuranyl)methyl)-N,N-dimethyl-. Grades: 98%. CAS No. 663214-64-0. Molecular formula: C27H27ClN6O4. Mole weight: 535.00. | |
| Aumitin | Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC 50 s of 0.12 μM and 0.24 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 946293-78-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124726. |  |
| DAP-81 | DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in ongoing preclinical evaluations. Synonyms: DAP81; DAP 81; DAP-81. N-(4-((4-((2-benzoylphenyl)amino)-5-nitropyrimidin-2-yl)amino)phenyl)acetamide. Grades: 98%. CAS No. 794466-17-4. Molecular formula: C25H20N6O4. Mole weight: 468.464. | |
| LRRK2 Inhibitor II, CZC-25146 (N- (2- (5-Fluoro-2- (2-methoxy-4-morpholinophenylamino) pyrimidin-4-ylamino) phenyl) methanesulfonamide, HCl, N- (2- (2- (2-Methoxy-4-morpholinophenylamino) -5-fluoropyrimidin-4-ylamino) phenyl) methanesulfonamide, HCl) | An orally bioavailable fluoro-diaminopyrimidine compound that acts as a potent, reversible and ATP-competitive inhibitor of LRRK2 activity (IC50=4.76 and 6.87nM for hr-wt-LRRK2 and G2019S-LRRK2 mutant, respectively) with selectivity over PLK4, GAK, TNK1, CAMKK2, and PIP4K2C (IC50 <300nM) in a 185-kinase panel. Does neither exert cytotoxicity nor block neuronal development of human or rat cortical neurons at 1uM. Shown to prevent GS-LRRK2-induced neuronal injury (EC50 ~4nM) and G2019S- or R1441C-LRRK2-mediated neuronal death in both rat and human cortical neurons (EC50 ~100nM). Even though exhibits favorable pharmacokinetic profile and metabolic stability, and yet suffers from limited blood brain barrier penetration (~4%). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Metoprine | A 2,4-Diaminopyrimidine derivative as antimalarial agent. Group: Biochemicals. Alternative Names: 5-(3,4-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine; 2,4-Diamino-5-(3,4-dichlorophenyl)-6-methylpyrimidine; 2,4-Diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine; BW 197U; BW 50197; DDMP; Methodichlorophen; NSC 19494; NSC 7364; SK 5265; U 197. Grades: Highly Purified. CAS No. 7761-45-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Metoprine | Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT [1] [2]. Metoprine is an antifolate and antitumor agent [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BW 197U. CAS No. 7761-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129441. | |
| Metoprine | Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT. Metoprine is an antifolate and antitumor agent. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(3,4-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine; 2,4-Diamino-5-(3,4- dichlorophenyl)-6-methylpyrimidine; 2,4-Diamino-5-(3',4'-dichlorophenyl)- 6-methylpyrimidine; BW 197U; BW 50197; DDMP; Methodichlorophen; NSC 19494; NSC 7364; SK 5265; U 197. Product Category: Inhibitors. Appearance: Solid. CAS No. 7761-45-7. Molecular formula: C11H10Cl2N4. Mole weight: 269.13. Purity: 0.96. IUPACName: 5-(3,4-dichlorophenyl)-6-methylpyrimidine-2,4-diamine. Canonical SMILES: CC1=C(C(=NC(=N1)N)N)C2=CC(=C(C=C2)Cl)Cl. Density: 1.447g/cm³. Product ID: ACM7761457. Alfa Chemistry ISO 9001:2015 Certified. | |
| Minoxidil Impurity A | 6-Chloro-pyrimidine-2,4-diamine 3-Oxide is an impurity of the antihypertensive and antialopecia agent Minoxidil. Synonyms: 6-Chloro-pyrimidine-2,4-diamine 3-Oxide; 2,6-Diamino-4-chloropyrimidine 1-Oxide; 2,4-Diamino-6-chloropyrimidine 3-N-Oxide; 2,4-Diamino-6-chloropyrimidine 3-Oxide; 6-Chloro-2,4-diaminopyrimidine 3-Oxide; NSC 137211. Grades: > 95%. CAS No. 35139-67-4. Molecular formula: C4H5ClN4O. Mole weight: 160.56. | |
| Minoxidil Impurity B | Synonyms: 6-Chloro-pyrimidine-2,4-diamine; 6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine; NSC 8818. Grades: > 95%. CAS No. 156-83-2. Molecular formula: C4H5ClN4. Mole weight: 144.56. | |
| Minoxidil Impurity D | 2,6-Diamino-4-pyrimidinyl p-Toluenesulfonate 3-Oxide is used in the preparation of a hypotensive drug. It is an intermediate in the preparation of Minoxidil. Synonyms: 2,6-Diamino-4-pyrimidinyl p-Toluenesulfonate 3-Oxide; 2,6-Diamino-4-pyrimidinol 4-(4-Methylbenzenesulfonate) 1-Oxide; 6-Tosyloxy-2,4-diaminopyrimidine 3-Oxide. Grades: > 95%. CAS No. 75105-16-7. Molecular formula: C11H12N4O4S. Mole weight: 296.3. | |
| Pyrimethamine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspesticides & metabolitespharma & vet compounds & metabolitespesticides & metabolitespharma & vet compounds & metabolitesapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: WR 2978, Chloridine,Pyrimethamine, Chloridin, 5-(4-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine, BW 50-63, 2,4-Diamino-5-p-chlorophenyl-6-ethylpyrimidine, Pirimetamin, 5-(P-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine, Diaminopyritamin, Tindurin, Darachlor, Khloridin, Pirimecidan, Malacid, RP 4753, Daraprim, Pyrimethamin, Tinduring, 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine, 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine, Erbaprelina, Daraprime, Malocide, Malocid, Pyrimethamine, NSC 3061, 4753 R.P., Darapram. |  |
| R547 | R547 is orally bioavailable diaminopyrimidine cyclin-dependent kinase inhibitor (CDKI) with potential antineoplastic activity. CDKI R547 selectively binds to and inhibits CDKs, especially CDK1/cyclin B, CDK2/cyclin E, and CDK4/cyclin D1. The inhibition of CDKs results in cell cycle arrest, inhibition of tumor cell proliferation, and induction of apoptosis. Through CDK inhibition, this agent also reduces phosphorylation of the retinoblastoma (Rb) protein, thus preventing activation of transcription factor E2F and so further suppressing tumor cell proliferation. CDKs are ATP-dependent serine/threonine kinases that are important regulators of cell cycle progression and are frequently overexpressed in tumor cells. Synonyms: RO-4584820; RO4584820; RO 4584820. R 547; R547; R-547. Grades: >98%. CAS No. 741713-40-6. Molecular formula: C18H21F2N5O4S. Mole weight: 441.45. | |
| Trimethoprim Impurity F | 3-Desmethoxy-3-bromo Trimethoprim is an impurity of Trimethoprim that inhibits the enzyme dihydrofolate reductase. Synonyms: 3-Desmethoxy-3-bromo Trimethoprim; 5-[(3-Bromo-4,5-dimethoxyphenyl)methyl]-2,4-diaminopyrimidine; 2,4-Diamino-5-(5-bromoveratryl)pyrimidine; 2,4-Diamino-5-(3,4-dimethoxy-5-bromobenzyl)pyrimidine; 2,4-Diamino-5-(3-bromo-4,5-dimethoxybenzyl)pyrimidine; 5-(3'-Bromo-4',5'-dimethoxybenzyl)-2,4-diaminopyrimidine. CAS No. 16285-82-8. Molecular formula: C13H15BrN4O2. Mole weight: 339.19. | |
| 2-[4-[(2,4-Diaminopyrimidin-5-yl)methyl]-2,6-dimethoxyphenyl]propan-2-ol | 2-[4-[(2,4-Diaminopyrimidin-5-yl)methyl]-2,6-dimethoxyphenyl]propan-2-ol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DHFR inhibitor, AIDS007520, AIDS-007520, CID41526, BRN 0764351, LS-42801, 5-25-13-00440 (Beilstein Handbook Reference), 2,4-Pyrimidinediamine, 5-(4-(1-hydroxy-1-methylethyl)-3,5-dimethoxybenzyl)-, 2-Propanol, 2-(4-(2,4-diamino-5-pyrimidinylmethyl)-2,6-dimethoxyphenyl)-, Benzyl alcohol, 4-(2,4-diamino-5-pyrimidinylmethyl)-2,6-dimethoxy-alpha,alpha-dimethyl-, 2,4-Diamino-5-[3,5-dimethoxy-4-(2-hydroxyprop-2-yl)benzyl]pyrimidine, 55687-91-7. Product Category: Heterocyclic Organic Compound. CAS No. 55687-91-7. Molecular formula: C16H22N4O3. Mole weight: 318.371 g/mol. Purity: 0.96. IUPACName: 2-[4-[(2,4-diaminopyrimidin-5-yl)methyl]-2,6-dimethoxyphenyl]propan-2-ol. Canonical SMILES: CC(C)(C1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC)O. Density: 1.245g/cm³. Product ID: ACM55687917. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2,4-Diamino-6-hydroxypyrimidine | 2,4-Diamino-6-hydroxypyrimidine. Group: Biochemicals. Alternative Names: 2,6-Diamino-4(1H)-pyrimidinone; 2,6-Diaminopyrimidin-4-one; 6-Aminoisocytosine; NSC 44914; NSC 680818; NSC 9302. Grades: Highly Purified. CAS No. 56-06-4. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| 2-Amino-6-bromo-3-fluoro-benzoic Acid | 2-Amino-6-bromo-3-fluoro-benzoic Acid is an intermediate used to prepare 2, 4-diaminopyrimidinyl aminoethyl quinazolin-4 (3H) -one derivatives as phosphatidylinositol 3-kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1153974-98-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C7H5BrFNO2, Molecular Weight: 234.02. US Biological Life Sciences. | Worldwide |
| ACP-TMP | ACP-TMP is a derivative of Trimethoprim, which inhibits the enzyme dihydrofolate reductase. Synonyms: 3-Chloro-N- (17- (4- ( (2, 4-diaminopyrimidin-5-yl) methyl) -2, 6-dimethoxyphenoxy) -15-oxo-4, 7, 10-trioxa-14-azaheptadecyl) -4- ( (2- (2-methyl-2- ( (5- (trifluoromethyl) pyridin-2-yl) sulfonyl) propanamido) ethyl) thio) benzamide; Acp-tmp. Molecular formula: C45H58ClF3N8O11S2. Mole weight: 1043.57. | |
| LRRK2 Inhibitor III, HG-10-102-01 (Leucine-Rich Repeat Kinase 2 Inhibitor III, Mixed-Lineage Kinase 1 Inhibitor I, MLK1 Inhibitor I, MNK Inhibitor III, (4- (5-Chloro-4- (methylamino)pyrimidin-2-ylamino)-3-methoxyphenyl) (morpholino)methanone) | A cell-permeable 2,4-diaminopyrimidinyl compound that acts as a potent, ATP-competitive LRRK2-selective inhibitor (IC5050 = 20.3, 3.2, 153.7 and 95.9nM, respectively,against human wt LRRK2 and G2019S, A2016T, G2019S/A2016T LRRK2 mutant; [ATP] = 100uM), displaying much reduced potency against MNK2 and MLK1 (IC50 = 0.6 and 2.1uM, respectively; [ATP] = 100uM) and little activity toward a panel of 136 other kinases. Although both HG-10-102-01 and LRRK2-In-1 inhibit cellular wt and G20195 LRRK2 phosphorylation (Optimal conc. 1 to 3uM), only HG-10-102-01 is effective against cellular A2016T and G2019S/A2016T LRRK2 phosphorylations (IC50 <3uM). And only HG-10-102-01, but not LRRK2-In-1 or CZC-25146, can cross blood-brain-barrier for LRRK2 phosphorylation inhibition in mice (30mg/kg to 50mg/kg i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?. US Biological Life Sciences. | Worldwide |
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