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| Product | Description | |
|---|---|---|
| 2,4-Diaminopyrimidine | 2,4-Diaminopyrimidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 156-81-0. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C4H6N4. US Biological Life Sciences. |  Worldwide |
| 2,4-Diaminopyrimidine | 2,4-Diaminopyrimidine. Uses: Designed for use in research and industrial production. Product Category: Pyrimidines. Appearance: White to Yellow Powder or Crystal or Chunk(s). CAS No. 156-81-0. Molecular formula: C4H6N4. Mole weight: 110.12. Purity: 0.98. Product ID: ACM156810. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2,4-Diaminopyrimidine 3-N-Oxide | 2,4-Diaminopyrimidine 3-N-Oxide is a useful organic synthetic reagent for the preparation of pyrimidines and in the making of hair loss and skin care compositions. Group: Biochemicals. Grades: Highly Purified. CAS No. 74638-76-9. Pack Sizes: 250mg, 1g. Molecular Formula: C4H6N4O, Molecular Weight: 126.12. US Biological Life Sciences. | Worldwide |
| 2,4-diaminopyrimidine 3-oxide | 2,4-diaminopyrimidine 3-oxide. Uses: Designed for use in research and industrial production. CAS No. 74638-76-9. Molecular formula: C4H6N4O. Mole weight: 126.12. Purity: 0.99. Product ID: ACM74638769. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2,4-Diaminopyrimidine-5-carbaldehyde ≥95% | 2,4-Diaminopyrimidine-5-carbaldehyde ≥95%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| 2,4-Diaminopyrimidine-5-carbonitrile | Intermediate for the preparation of medicines and agrochemicals. Group: Biochemicals. Alternative Names: 2,4-Diamino-5-cyanopyrimidine; 2, 4-Diamino-5-pyrimidinecarbonitri le; NSC 135235. Grades: Highly Purified. CAS No. 16462-27-4. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2,4-Diaminopyrimidine-5-carbonitrile ≥95% | 2,4-Diaminopyrimidine-5-carbonitrile ≥95%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| 2,4-Diaminopyrimidine-5-carboxaldehyde | Intermediate for the preparation of medicines and agrochemicals. Group: Biochemicals. Alternative Names: 2, 4-Diamino-5-pyrimidinecarboxalde hyde; 2, 6-Diamino-5-pyrimidinecarboxalde hyde; NSC 211353. Grades: Highly Purified. CAS No. 20781-06-0. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 2,5-Diaminopyrimidine (2-aminopyrimidin-5-yl)amine) | 2,5-Diaminopyrimidine (2-aminopyrimidin-5-yl)amine). CAS No: 22715-27-1 |  Sarchem Laboratories New Jersey NJ |
| 2-Chloro-4,5-diaminopyrimidine | 2-Chloro-4,5-diaminopyrimidine. CAS No: 14631-08-4 | Sarchem Laboratories New Jersey NJ |
| 2-Chloro-4,5-diaminopyrimidine | 2-Chloro-4,5-diaminopyrimidine. Group: Biochemicals. Grades: Highly Purified. CAS No. 14631-08-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C4H5ClN4. US Biological Life Sciences. | Worldwide |
| 4,5-Diaminopyrimidine | 4,5-Diaminopyrimidine. CAS No: 13754-19-3 | Sarchem Laboratories New Jersey NJ |
| 4,5-Diaminopyrimidine | 4,5-Diaminopyrimidine is an intermediate in the synthesis of Nisin, a compound that was first introduced as a good preservative and was later on discovered to have antibacterial activity against gram positive bacteria. 4,5-Diaminopyrimidine is also used as a reagent to synthesize uracil-based 2-aminoanilide derivatives, compounds that act as histone deacetylase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 13754-19-3. Pack Sizes: 1g, 5g. Molecular Formula: C4H6N4, Molecular Weight: 110.12. US Biological Life Sciences. | Worldwide |
| 4,5-Diaminopyrimidine | 4,5-Diaminopyrimidine. Uses: Designed for use in research and industrial production. Product Category: Pyrimidines. Appearance: White to Yellow to Tan Powder. CAS No. 13754-19-3. Molecular formula: C4H6N4. Mole weight: 110.12. Purity: 0.95. Product ID: ACM13754193. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4,6-Diaminopyrimidine | 4,6-Diaminopyrimidine. Group: Biochemicals. Alternative Names: 4,6-Pyrimidinediamine; NSC 211429. Grades: Highly Purified. CAS No. 2434-56-2. Pack Sizes: 2.5g. Molecular Formula: C4H6N4, Molecular Weight: 110.12. US Biological Life Sciences. | Worldwide |
| 4,6-Diaminopyrimidine hemisulfate 1-hydrate | 4,6-Diaminopyrimidine hemisulfate 1-hydrate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,6-DIAMINOPYRIMIDINE HEMISULFATE, MONOHYDRATE, 98;pyrimidine-4,6-diammonium hydrogen sulphate (1:2);4,6-DIAMINOPYRIMIDINE HEMISULFATE MONO- HYDRATE 98%;4,6-Pyrimidinediamine hemisulfate. Product Category: Heterocyclic Organic Compound. CAS No. 77709-02-5. Molecular formula: C4H8N4O. Mole weight: 336.331. Product ID: ACM77709025. Alfa Chemistry ISO 9001:2015 Certified. Categories: 207226-28-6. | |
| 4-Chloro-2,6-diaminopyrimidine | 4-Chloro-2,6-diaminopyrimidine. Group: Biochemicals. Alternative Names: 6-chloro-2,4-diamino-pyrimidine. Grades: Highly Purified. CAS No. 156-83-2. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C4H5ClN4. US Biological Life Sciences. | Worldwide |
| 4-Chloro-2,6-diaminopyrimidine 99+% (HPLC) | 4-Chloro-2,6-diaminopyrimidine 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5g, 25g, 100g, 250g, 1Kg. US Biological Life Sciences. | Worldwide |
| 6-Chloro-pyrimidine-2,4-diamine (6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine) | 6-Chloro-pyrimidine-2,4-diamine (6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine). Group: Biochemicals. Alternative Names: 6-Chloro-pyrimidine-2,4-diyldiamine, 4-Chloro-2,6-diaminopyrimidine. Grades: Highly Purified. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 1-Methanesulfonyl-2-morpholino-4-nitrobenzene | 1-Methanesulfonyl-2-morpholino-4-nitrobenzene acts as a reagent for the preparation of diaminopyrimidinecarbo xamide derivatives as SYK kinase inhibitors useful in treatment and prevention of SYK kinase-mediated diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 1194974-72-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C11H14N2O5S, Molecular Weight: 286.3. US Biological Life Sciences. | Worldwide |
| 1-Methyl-4-(4-nitrophenyl)piperazine | 1-methyl-4-(4-nitrophenyl)piperazine was a reagent in the preparation of diaminopyrimidines as reversible and irreversible inhibitors of mutant EGFR tyrosine kinases for treatment of non-small-cell lung cancer. It was also used in the prepn. of disubstituted pyrimidine compds. as EGFR or/and ALK inhibitors useful in the treatment of diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 16155-03-6. Pack Sizes: 500mg, 1g. Molecular Formula: C11H15N3O2, Molecular Weight: 221.26. US Biological Life Sciences. | Worldwide |
| 2, 4-Bis (benzylamino) pyrimidine | 2, 4-Bis (benzylamino) pyrimidine is an intermediate in the synthesis of pro-apoptotic agents based on 2,4-diaminoquinazoline, 2,4-diaminopyrido[2,3-d]pyrimidine and 2,4-diaminopyrimidine derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 65448-40-0. Pack Sizes: 250mg, 500mg. Molecular Formula: C18H18N4. US Biological Life Sciences. | Worldwide |
| 2,4-Diamino-6-hydroxypyrimidine | 2,4-Diamino-6-hydroxypyrimidine has been found to be a GCH1 inhibitor and could suppress the activity of NO synthase through preventing the synthesis of BH4. Uses: Enzyme inhibitors. Synonyms: 2,6-Diamino-4(1H)-pyrimidinone; 2,6-Diaminopyrimidin-4-one; 6-Aminoisocytosine; NSC 44914; NSC 680818; NSC 9302; 4(3H)-Pyrimidinone, 2,6-diamino-; 2,6-Diamino-4(3H)-pyrimidinone; 4(1H)-Pyrimidinone, 2,6-diamino-; 2,4-Diamino-6-pyrimidinone; 2,6-Diamino-1,4-dihydropyrimidin-4-one; 2,6-Diamino-1H-pyrimidin-4-one; 2,6-Diamino-3,4-dihydropyrimidin-4-one; 2,6-Diamino-3H-pyrimidin-4-one; 2,6-Diamino-4-pyrimidinol; 4-Hydroxypyrimidine-2,6-diamine; 6-Hydroxy-2,4-diaminopyrimidine; 6-Hydroxy-2,4-pyrimidinediamine. Grade: ≥95%. CAS No. 56-06-4. Molecular formula: C4H6N4O. Mole weight: 126.12. |  |
| 2, 4-Dichloro-6-trifluoro methyl pyrimidine | 2, 4-Dichloro-6-trifluoro methyl pyrimidine is a useful synthetic intermediate. It can be used to synthesize 2,4-diaminopyrimidines derivatives that show antiplasmodial activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 16097-64-6. Pack Sizes: 1g, 2.5g. Molecular Formula: C5HCl2F3N2, Molecular Weight: 216.98. US Biological Life Sciences. | Worldwide |
| 2,6-Diamino-4-chloropyrimidine | 2,6-Diamino-4-chloropyrimidine. Uses: Designed for use in research and industrial production. Product Category: Pyrimidines. Appearance: White to Tan Powder or Crystals. CAS No. 156-83-2. Molecular formula: C4H5ClN4. Mole weight: 144.56. Purity: 0.98. Product ID: ACM156832. Alfa Chemistry ISO 9001:2015 Certified. Categories: 4-Chloro-2,6-diaminopyrimidine. | |
| 2,6-Diamino-4-chloropyrimidine 1-oxide | 2,6-Diamino-4-chloropyrimidine 1-oxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TIMTEC-BB SBB003960;2,4-PYRIMIDINEDIAMINE, 6-CHLORO-, 3-OXIDE;2,6-DIAMINO-4-CHLOROPYRIMIDINE 1-OXIDE;6-CHLORO-3-OXY-PYRIMIDINE-2,4-DIAMINE;4-Chloro-2,6-Diaminopyrimidine-N-Oxide;6-Chloro-2,4-diaminopyrimidine-N-oxide;2,4-DIAMINO-6-CHLORO PYRIMIDINE 97.0%. Product Category: Polymer/Macromolecule. CAS No. 35139-67-4. Molecular formula: C4H5ClN4O. Mole weight: 160.56. Product ID: ACM35139674. Alfa Chemistry ISO 9001:2015 Certified. Categories: 34960-71-9. | |
| 2,6-Diamino-4-pyrimidinyl p-Toluenesulfonate 3-Oxide | 2,6-Diamino-4-pyrimidinyl p-Toluenesulfonate 3-Oxide. Group: Biochemicals. Alternative Names: 2,6-Diamino-4-pyrimidinol 4- (4-Methyl Benzene sulfonate) 1-Oxide; 6-Tosyloxy-2,4-diaminopyrimidine 3-Oxide. Grades: Highly Purified. CAS No. 75105-16-7. Pack Sizes: 100mg. Molecular Formula: C11H12N4O4S, Molecular Weight: 296.3. US Biological Life Sciences. | Worldwide |
| 2-Iodoanisole | 2-Iodoanisole is a useful synthetic intermediate. It can be used in the synthesis of piperidinyl diaminopyrimidines as cyclin-dependent kinase inhibitors with antitumor activity and polysubstituted benzofuran derivatives as novel inhibitors of parasitic growth. Group: Biochemicals. Grades: Highly Purified. CAS No. 529-28-2. Pack Sizes: 10g, 25g. Molecular Formula: C7H7IO, Molecular Weight: 234.03. US Biological Life Sciences. | Worldwide |
| 2-?Nitrophenethylamine Hydrochloride | 2-?Nitrophenethylamine Hydrochloride is used in preparation of diaminopyrimidines as MTH-1 inhibitors for treament of cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 861337-74-8. Pack Sizes: 500mg, 1g. Molecular Formula: C8H10N2O2; HCl, Molecular Weight: 166.183646. US Biological Life Sciences. | Worldwide |
| 4,6-Diamino-2-mercaptopyrimidine | 4,6-Diamino-2-mercaptopyrimidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Mercapto-4,6-diaminopyrimidine, 4,6-Diamino-2-thiopyrimidine, 4,6-Diamino-2-mercaptopyrimidine, 2(1H)-Pyrimidinethione, 4,6-diamino-, 4,6-Diaminopyrimidine-2-thiol, NSC1586, NSC680831, AIDS023077, AIDS-023077, NSC 1586, EINECS 213-721-2, SBB004143, SBB007564, ZINC00967453, ZINC04284766, 4,6-diaminopyrimidine-2(3H)-thione, NSC 680831, AI3-52092, AG-670/32486009, 1004-39-3. Product Category: Heterocyclic Organic Compound. Appearance: Brown-Grey Solid. CAS No. 1004-39-3. Molecular formula: C4H6N4S. Mole weight: 142.18. Purity: N/A. IUPACName: 4,6-diamino-1H-pyrimidine-2-thione. Canonical SMILES: C1=C(NC(=S)N=C1N)N. Density: 1.78 g/cm³. ECNumber: 213-721-2. Product ID: ACM1004393. Alfa Chemistry ISO 9001:2015 Certified. | |
| 4-Desmethoxy-4-bromo Trimethoprim | An impurity of Trimethoprim with inhibitory effects on the enzyme dihydrofolate reductase. Group: Biochemicals. Alternative Names: 5-[ (3-Bromo-4, 5-dimethoxyphenyl) methyl]-2, 4-diaminopyrimidine; 2, 4-Diamino-5- (5-bromoveratryl) pyrimidine; 2, 4-Diamino-5- (3, 4-dimethoxy-5-bromobenzyl) pyrimidine; 2, 4-Diamino-5- (3-bromo-4, 5-dimethoxybenzyl) pyrimidine; 5-(3'-Bromo-4',5'-dimethoxybenzyl)-2,4-diaminopyrimidine. Grades: Highly Purified. CAS No. 16285-82-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 5,6-Diaminouracil | 5,6-Diaminouracil (CAS# 3240-72-0) is a useful research chemical. Synonyms: 5,6-Diamino-2,4-dihydroxypyrimidine; 4,5-Diaminouracil; 5,6-diamino-1H-pyrimidine-2,4-dione; 2,4(1H,3H)-Pyrimidinedione, 5,6-diamino-, monohydrochloride; 5,6-DIAMINOURACIL MONOHYDROCHLORIDE; 5,6-diaminopyrimidine-2,4(1H,3H)-dione; 4,5-DIAMINOURACIL,HYDROCHLORIDE SALT. Grade: ≥ 95 %. CAS No. 3240-72-0. Molecular formula: C4H7ClN4O2. Mole weight: 178.58. | |
| 6-Aminoquinoline | 6-Aminoquinoline is used in the preparation of diaminopyrimidine derivatives as 5-HT4 receptor agonists. Group: Biochemicals. Alternative Names: (Quinolin-6-yl)amine; 6-Quinolylamine; NSC 58388. Grades: Highly Purified. CAS No. 580-15-4. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| 6-Ethyl-5-(4-nitrophenyl)-2,4-pyrimidinediamine | A diaminopyrimidine derivative with antimalarial and antibacterial properties. Group: Biochemicals. Alternative Names: 2,4-Diamino-6-ethyl-5-(p-nitrophenyl)-pyrimidine; NSC 372954. Grades: Highly Purified. CAS No. 71552-34-6. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| α-(1-Methoxypropylidene)-4-nitro-benzeneacetonitrile | Used in the preparation of 2,4-diaminopyrimidine growth hormone secretagogue receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 885428-60-4. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| AR709 | AR709 is a novel diaminopyrimidine antibiotic. It is currently in development for treatment of community-acquired upper and lower respiratory tract infections. It showed excellent activity against both drug-susceptible and multidrug-resistant pneumococci. Uses: Ar709 is currently in development for treatment of community-acquired upper and lower respiratory tract infections. Synonyms: AR-709; AR 709; 1H-Indole-2-carboxamide, 5-chloro-3-((4-((2,4-diamino-5-pyrimidinyl)methyl)-6,7-dimethoxy-2-benzofuranyl)methyl)-N,N-dimethyl-. Grade: 98%. CAS No. 663214-64-0. Molecular formula: C27H27ClN6O4. Mole weight: 535.00. | |
| Aumitin | Aumitin is a diaminopyrimidine-based autophagy inhibitor which inhibits mitochondrial respiration by targeting complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC 50 s of 0.12 μM and 0.24 μM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 946293-78-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124726. |  |
| DAP-81 | DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in ongoing preclinical evaluations. Synonyms: DAP81; DAP 81; DAP-81. N-(4-((4-((2-benzoylphenyl)amino)-5-nitropyrimidin-2-yl)amino)phenyl)acetamide. Grade: 98%. CAS No. 794466-17-4. Molecular formula: C25H20N6O4. Mole weight: 468.464. | |
| Iclaprim | Iclaprim is a diaminopyrimidine and acts as a dihydrofolate reductase (DHFR) inhibitor active against gram-positive organisms being developed for the treatment of complicated skin and soft tissue infections caused by antibiotic-resistant bacteria. Synonyms: AR-100; 5-[(2-cyclopropyl-7,8-dimethoxy-2h-chromen-5-yl)methyl]pyrimidine-2,4-diamine; RO-48-2622. CAS No. 192314-93-5. Molecular formula: C19H22N4O3. Mole weight: 354.41. | |
| LRRK2 Inhibitor II, CZC-25146 (N- (2- (5-Fluoro-2- (2-methoxy-4-morpholinophenylamino) pyrimidin-4-ylamino) phenyl) methanesulfonamide, HCl, N- (2- (2- (2-Methoxy-4-morpholinophenylamino) -5-fluoropyrimidin-4-ylamino) phenyl) methanesulfonamide, HCl) | An orally bioavailable fluoro-diaminopyrimidine compound that acts as a potent, reversible and ATP-competitive inhibitor of LRRK2 activity (IC50=4.76 and 6.87nM for hr-wt-LRRK2 and G2019S-LRRK2 mutant, respectively) with selectivity over PLK4, GAK, TNK1, CAMKK2, and PIP4K2C (IC50 <300nM) in a 185-kinase panel. Does neither exert cytotoxicity nor block neuronal development of human or rat cortical neurons at 1uM. Shown to prevent GS-LRRK2-induced neuronal injury (EC50 ~4nM) and G2019S- or R1441C-LRRK2-mediated neuronal death in both rat and human cortical neurons (EC50 ~100nM). Even though exhibits favorable pharmacokinetic profile and metabolic stability, and yet suffers from limited blood brain barrier penetration (~4%). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Metoprine | A 2,4-Diaminopyrimidine derivative as antimalarial agent. Group: Biochemicals. Alternative Names: 5-(3,4-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine; 2,4-Diamino-5-(3,4-dichlorophenyl)-6-methylpyrimidine; 2,4-Diamino-5-(3',4'-dichlorophenyl)-6-methylpyrimidine; BW 197U; BW 50197; DDMP; Methodichlorophen; NSC 19494; NSC 7364; SK 5265; U 197. Grades: Highly Purified. CAS No. 7761-45-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Metoprine | Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT [1] [2]. Metoprine is an antifolate and antitumor agent [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BW 197U. CAS No. 7761-45-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-129441. | |
| Metoprine | Metoprine (BW 197U) is a potent histamine N-methyltransferase (HMT) inhibitor. Metoprine, a diaminopyrimidine derivative, can cross the blood-brain barrier and increase brain histamine levels by inhibiting HMT. Metoprine is an antifolate and antitumor agent. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-(3,4-Dichlorophenyl)-6-methyl-2,4-pyrimidinediamine; 2,4-Diamino-5-(3,4- dichlorophenyl)-6-methylpyrimidine; 2,4-Diamino-5-(3',4'-dichlorophenyl)- 6-methylpyrimidine; BW 197U; BW 50197; DDMP; Methodichlorophen; NSC 19494; NSC 7364; SK 5265; U 197. Product Category: Inhibitors. Appearance: Solid. CAS No. 7761-45-7. Molecular formula: C11H10Cl2N4. Mole weight: 269.13. Purity: 0.96. IUPACName: 5-(3,4-dichlorophenyl)-6-methylpyrimidine-2,4-diamine. Canonical SMILES: CC1=C(C(=NC(=N1)N)N)C2=CC(=C(C=C2)Cl)Cl. Density: 1.447g/cm³. Product ID: ACM7761457. Alfa Chemistry ISO 9001:2015 Certified. | |
| Pyrimethamine | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardspesticides & metabolitespharma & vet compounds & metabolitespesticides & metabolitespharma & vet compounds & metabolitesapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)pharmaceutical toxicologypharmacopoeial standards. Alternative Names: WR 2978, Chloridine,Pyrimethamine, Chloridin, 5-(4-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine, BW 50-63, 2,4-Diamino-5-p-chlorophenyl-6-ethylpyrimidine, Pirimetamin, 5-(P-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine, Diaminopyritamin, Tindurin, Darachlor, Khloridin, Pirimecidan, Malacid, RP 4753, Daraprim, Pyrimethamin, Tinduring, 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine, 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine, Erbaprelina, Daraprime, Malocide, Malocid, Pyrimethamine, NSC 3061, 4753 R.P., Darapram. |  |
| 2-[4-[(2,4-Diaminopyrimidin-5-yl)methyl]-2,6-dimethoxyphenyl]propan-2-ol | 2-[4-[(2,4-Diaminopyrimidin-5-yl)methyl]-2,6-dimethoxyphenyl]propan-2-ol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DHFR inhibitor, AIDS007520, AIDS-007520, CID41526, BRN 0764351, LS-42801, 5-25-13-00440 (Beilstein Handbook Reference), 2,4-Pyrimidinediamine, 5-(4-(1-hydroxy-1-methylethyl)-3,5-dimethoxybenzyl)-, 2-Propanol, 2-(4-(2,4-diamino-5-pyrimidinylmethyl)-2,6-dimethoxyphenyl)-, Benzyl alcohol, 4-(2,4-diamino-5-pyrimidinylmethyl)-2,6-dimethoxy-alpha,alpha-dimethyl-, 2,4-Diamino-5-[3,5-dimethoxy-4-(2-hydroxyprop-2-yl)benzyl]pyrimidine, 55687-91-7. Product Category: Heterocyclic Organic Compound. CAS No. 55687-91-7. Molecular formula: C16H22N4O3. Mole weight: 318.371 g/mol. Purity: 0.96. IUPACName: 2-[4-[(2,4-diaminopyrimidin-5-yl)methyl]-2,6-dimethoxyphenyl]propan-2-ol. Canonical SMILES: CC(C)(C1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC)O. Density: 1.245g/cm³. Product ID: ACM55687917. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2,4-Diamino-6-hydroxypyrimidine | 2,4-Diamino-6-hydroxypyrimidine. Group: Biochemicals. Alternative Names: 2,6-Diamino-4(1H)-pyrimidinone; 2,6-Diaminopyrimidin-4-one; 6-Aminoisocytosine; NSC 44914; NSC 680818; NSC 9302. Grades: Highly Purified. CAS No. 56-06-4. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| 2-Amino-6-bromo-3-fluoro-benzoic Acid | 2-Amino-6-bromo-3-fluoro-benzoic Acid is an intermediate used to prepare 2, 4-diaminopyrimidinyl aminoethyl quinazolin-4 (3H) -one derivatives as phosphatidylinositol 3-kinase inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1153974-98-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C7H5BrFNO2, Molecular Weight: 234.02. US Biological Life Sciences. | Worldwide |
| ACP-TMP | ACP-TMP is a derivative of Trimethoprim, which inhibits the enzyme dihydrofolate reductase. Synonyms: 3-Chloro-N-(17-(4-((2,4-diaminopyrimidin-5-yl)methyl)-2,6-dimethoxyphenoxy)-15-oxo-4,7,10-trioxa-14-azaheptadecyl)-4-((2-(2-methyl-2-((5-(trifluoromethyl)pyridin-2-yl)sulfonyl)propanamido)ethyl)thio)benzamide; Acp-tmp. Molecular formula: C45H58ClF3N8O11S2. Mole weight: 1043.57. | |
| LRRK2 Inhibitor III, HG-10-102-01 (Leucine-Rich Repeat Kinase 2 Inhibitor III, Mixed-Lineage Kinase 1 Inhibitor I, MLK1 Inhibitor I, MNK Inhibitor III, (4- (5-Chloro-4- (methylamino)pyrimidin-2-ylamino)-3-methoxyphenyl) (morpholino)methanone) | A cell-permeable 2,4-diaminopyrimidinyl compound that acts as a potent, ATP-competitive LRRK2-selective inhibitor (IC5050 = 20.3, 3.2, 153.7 and 95.9nM, respectively,against human wt LRRK2 and G2019S, A2016T, G2019S/A2016T LRRK2 mutant; [ATP] = 100uM), displaying much reduced potency against MNK2 and MLK1 (IC50 = 0.6 and 2.1uM, respectively; [ATP] = 100uM) and little activity toward a panel of 136 other kinases. Although both HG-10-102-01 and LRRK2-In-1 inhibit cellular wt and G20195 LRRK2 phosphorylation (Optimal conc. 1 to 3uM), only HG-10-102-01 is effective against cellular A2016T and G2019S/A2016T LRRK2 phosphorylations (IC50 <3uM). And only HG-10-102-01, but not LRRK2-In-1 or CZC-25146, can cross blood-brain-barrier for LRRK2 phosphorylation inhibition in mice (30mg/kg to 50mg/kg i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?. US Biological Life Sciences. | Worldwide |
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