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Dibenz[a,h]anthracene (DBA) is a polycyclic aromatic hydrocarbon (PAH) of considerable tumorigenicity. Dibenz[a,h]anthracene results in DNA adduct formation leading to the activation of a DNA damage response. Dibenz[a,h]anthracene induces cell cycle arrest and apoptosis via both Tp53-dependent and Tp53-independent mechanisms [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DBA; 1,2,5,6-Dibenzanthracene; Benzo[k]tetraphene. CAS No. 53-70-3. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-W013053.
Dibenz[a,h]anthracene
Dibenz[a,h]anthracene is a polycyclic aromatic hydrocarbon (PAH) and a known carcinogen. Dibenz[a,h]anthracene has produced positive results in bacterial DNA damage and mutagenicity assays and in mammalian cell DNA damage, mutagenicity and cell transformation assays. Group: Biochemicals. Alternative Names: 1,2:5,6-Benzanthracene; 1,2:5,6-Dibenz[a]anthracene; 1,2:5,6-Dibenzanthracen; 1,2:5,6-Dibenzanthracene; 1,2:5,6-Dibenzoanthracene; DBA; Dibenzo[a, h]anthracene; NSC 22433. Grades: Highly Purified. CAS No. 53-70-3. Pack Sizes: 100mg. US Biological Life Sciences.
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Dibenz[a,h]anthracene-d14
Labeled analogue of Dibenz[a,h]anthracene, a polycyclic aromatic hydrocarbon (PAH) and a known carcinogen. Dibenz[a,h]anthracene has produced positive results in bacterial DNA damage and mutagenicity assays and in mammalian cell DNA damage, mutagenicity and cell transformation assays. Group: Biochemicals. Alternative Names: 1,2:5,6-Benzanthracene-d14; 1,2:5,6-Dibenz[a]anthracene-d14; 1,2:5,6-Dibenzanthracen-d14; 1,2:5,6-Dibenzanthracene-d14; 1,2:5,6-Dibenzoanthracene-d14; DBA; Dibenzo[a,h]anthracene-d14; NSC 22433-d14. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
A heterocyclic aromatic compound with potent mutagenic and carcinogenic properties. Group: Biochemicals. Alternative Names: 1,2,7,8-Dibenzacridine, 7-Azadibenz[a, j]anthracene, Dibenz[a,f]acridine. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Dibenz[de, kl]anthracene
Dibenz[de, kl]anthracene. Group: Biochemicals. Alternative Names: Perylene; Peri-Dinaphthalene. Grades: Highly Purified. CAS No. 198-55-0. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences.
Worldwide
Dibenzo[a,c]anthracene
Dibenzo[a, c]anthracene. Group: Biochemicals. Alternative Names: Benzo[b]triphenylene; 1,2:3,4-Dibenzanthracene; 1,2:3,4-Dibenzoanthracene; 2,3-Benzotriphenylene; Dibenz[a,c]anthracene. Grades: Highly Purified. CAS No. 215-58-7. Pack Sizes: 50mg. Molecular Formula: C22H14, Molecular Weight: 278.35. US Biological Life Sciences.
Worldwide
Dibenzo[a,c]anthracene-13C6
Dibenzo[a,c]anthracene-13C6. Group: Biochemicals. Alternative Names: Benzo[b]triphenylene; 1,2:3,4-Dibenzanthracene; 1,2:3,4-Dibenzoanthracene; 2,3-Benzotriphenylene; Dibenz[a,c]anthracene. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C1613C6H14, Molecular Weight: 284.3. US Biological Life Sciences.
Benz[j]aceanthrylene-13C2,d2 and Benz[e]aceanthrylene-13C2,d2
Labeled Benz[j]aceanthrylene. Polycyclic aromatic hydrocarbons (PAHs) and their PAH-DNA adducts in lung tissues, and their ability to mutate the Ki-ras oncogene in PAH-induced tumors. Seven PAHs were studied: cyclopenta[cd]pyrene (CPP), benzo[a]pyrene (B[a]P), benzo[b]fluoranthene (B[b]F), dibenz[a,h]anthracene (DBA), 5-methylchrysene (5MC), benz[j]aceanthrylene (B[j]A), and dibenzo[a,l]pyrene (DB[a,l]P). Group: Biochemicals. Alternative Names: Benz[7,8]aceanthrylene-13C2,d2 and Benz[4,5]aceanthrylene-13C2,d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Benz[j]aceanthrylene and Benz[e]aceanthrylene (70:30 Mixture)
Polycyclic aromatic hydrocarbons (PAHs) and their PAH-DNA adducts in lung tissues, and their ability to mutate the Ki-ras oncogene in PAH-induced tumors. Seven PAHs were studied: cyclopenta[cd]pyrene (CPP), benzo[a]pyrene (B[a]P), benzo[b]fluoranthene (B[b]F), dibenz[a,h]anthracene (DBA), 5-methylchrysene (5MC), benz[j]aceanthrylene (B[j]A), and dibenzo[a,l]pyrene (DB[a,l]P). Group: Biochemicals. Alternative Names: Benz[7,8]aceanthrylene and Benz[4, 5]aceanthrylene. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Dibenz[a,h]acridine
Dibenz[a,h]acridine. Group: Biochemicals. Alternative Names: 1,2,5,6-Dibenzacridine; 1,2:5,6-Dibenzacridine; 7-Azadibenz[a, h]anthracene. Grades: Highly Purified. CAS No. 226-36-8. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H13N. US Biological Life Sciences.
Worldwide
Dibenz[a,h]acridine-d6 (Major)
Labeled Dibenz[a,h]acridine. A urinary metabolite from inhalation and dermal exposure to polycyclic aromatics hydrocarbons in hot mix asphalt paving workers. A heterocyclic aromatic compound with potent mutagenic and carcinogenic properties. Group: Biochemicals. Alternative Names: 1,2,5,6-Dibenzacridine-d6; 1,2:5,6-Dibenzacridine-d6; 7-Azadibenz[a, h]anthracene-d6; Dibenz[a,d]acridine-d6. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
Dibenz[a,j]acridine
Dibenz[a,j]acridine. Group: Biochemicals. Alternative Names: 1,2:7,8-Dibenzacridine; 7-Azadibenz[a, j]anthracene; Dibenz[a,f]acridine. Grades: Highly Purified. CAS No. 224-42-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C21H13N. US Biological Life Sciences.
Worldwide
Ethonafide
Ethonafide is an anthracene-containing derivative of amonafide that belongs to the azonafide series of anticancer agents. The lack of cross-resistance in multidrug-resistant cancer cell lines and the absence of a quinone and hydroquinone moiety make ethonafide a potentially less cardiotoxic replacement for existing anthracene-containing anticancer agents. Ethonafide was cytotoxic against three human prostate cancer cell lines at nanomolar concentrations. Ethonafide was found to be better tolerated and more effective at inhibiting tumor growth compared with mitoxantrone in a human xenograft tumor regression mouse model. Mechanistically, we found that ethonafide inhibited topoisomerase II activity by stabilizing the enzyme-DNA complex, involving both topoisomerase IIalpha and -beta. In addition, ethonafide induced a potent G(2) cell cycle arrest in the DU 145 human prostate cancer cell line. By creating stable cell lines with decreased expression of topoisomerase IIalpha or -beta, we found that a decrease in topoisomerase IIalpha protein expression renders the cell line resistant to ethonafide. The decrease in sensitivity to ethonafide was associated with a decrease in DNA damage and an increase in DNA repair as measured by the neutral comet assay. These data demonstrate that ethonafide is a topoisomerase II poison and that it is topoisomerase IIalpha-specific in the DU 145 human prostate cancer cell line. Uses: Topoisomerase ii inhibitors. Synonyms: AMP-53; AMP 53; AMP53; 2-(2'-(Dimethylamino)ethyl)-1,2-dihydro-7-ethoxydibenz(de, H)isoquinoline-1,3-dione; 2-[2-(Dimethylamino)ethyl]-7-ethoxy-1H-dibenz[de,h]isoquinoline-1,3(2H)-dione. CAS No. 175293-23-9. Molecular formula: C22H22N2O3. Mole weight: 362.43.
Pentacene is a polycyclic aromatic compound found in wastewater treatment facility units. Group: Biochemicals. Alternative Names: 2,3:6,7-Dibenzanthracene; Benzo[b]naphthacene; Dibenz[b,i]anthracene; NSC 90784; lin-Dibenzanthracene; lin-Naphthoanthracene. Grades: Highly Purified. CAS No. 135-48-8. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Pentacene-d14
Pentacene-d14. Group: Biochemicals. Alternative Names: 2,3:6,7-Dibenzanthracene-d14; Benzo[b]naphthacene-d14; Dibenz[b,i]anthracene-d14; NSC 90784-d14; lin-Dibenzanthracene-d14; lin-Naphthoanthracene-d14. Grades: Highly Purified. CAS No. 63912-16-3. Pack Sizes: 2.5mg. Molecular Formula: C22D14, Molecular Weight: 292.43. US Biological Life Sciences.
Worldwide
Perylene (purified by sublimation)
Perylene (purified by sublimation). Group: other material building blockscarbon nano materials molecular conductorsorganic light-emitting diode (oled) materials. Alternative Names: Dibenz[de,kl]anthracene (purified by sublimation) Peri-dinaphthalene (purified by sublimation). CAS No. 198-55-0. Product ID: perylene. Molecular formula: 252.32. Mole weight: C20H12. C1=CC2=C3C (=C1)C4=CC=CC5=C4C (=CC=C5)C3=CC=C2. InChI=1S / C20H12 / c1-5-13-6-2-11-17-18-12-4-8-14-7-3-10 -16 (20 (14) 18) 15 (9-1) 19 (13) 17 / h1-12H. CSHWQDPOILHKBI-UHFFFAOYSA-N. >99.0%(GC).
4,4'-Dibenzamido-1,1'-iminodianthraquinone
Heterocyclic Organic Compound. Alternative Names: 4,4'-dibenzamido-1,1'-iminodianthraquinone;N-[4-(4-benzoylimino-9,10-dioxo-anthracen-1-ylidene)amino-9,10-dihydroxy-anthracen-1-yl]benzamide;4,4''-DIBENZAMIDO-1,1''-DIANTHRIMIDE;C.I. VAT Black 28;C.I.65010;C.I.Vat Black 28;Mikethrene Grey K;Olive AR Anth. CAS No. 128-79-0. Molecular formula: C42H25N3O6. Mole weight: 667.6644. Catalog: ACM128790.