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| Product | Description | |
|---|---|---|
| Digitonin | 1g Pack Size. Group: Biochemicals, Research Organics & Inorganics. Formula: C56H92O29. CAS No. 11024-24-1. Prepack ID 84387497-1g. Molecular Weight 1229.31. See USA prepack pricing. |  |
| Digitonin | Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding to cholesterol molecules and reduce tumor growth [1]. Digitonin is an natural detergent [2]. Uses: Scientific research. Group: Natural products. CAS No. 11024-24-1. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-N4000. |  |
| Digitonin | Digitonin. Alternative Names: Digitin; NSC 23471; NSC 237417. CAS No. 11024-24-1. Molecular formula: C56H92O29. Mole weight: 1229.3. Appearance: A crystalline solid. Purity: 0.98. IUPACName: (2S, 3R, 4S, 5S, 6R)-2-[(2S, 3R, 4S, 5S, 6R)-2-[(2S, 3R, 4S, 5R, 6R)-2-[(2R, 3R, 4R, 5R, 6R)-6-[(1R, 2S, 3S, 4R, 5'R, 6R, 7S, 8R, 9S, 12S, 13S, 15R, 16R, 18S)-3, 15-dihydroxy-5', 7, 9, 13-tetramethylspiro[5-oxapentacyclo[10.8.0.02, 9.04, 8.013, 18]icosane-6, 2'-oxane]-16-yl]oxy-4, 5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)-4-[(2S, 3R, 4S, 5R)-3, 4, 5-trihydroxyoxan-2-yl]oxyoxan-3-yl]oxy-3, 5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-6-(hydroxymethyl)oxane-3, 4, 5-triol. Canonical SMILES: CC1CCC2 (C (C3C (O2)C (C4C3 (CCC5C4CCC6C5 (CC (C (C6)OC7C (C (C (C (O7)CO)OC8C (C (C (C (O8)CO)O)OC9C (C (C (CO9)O)O)O)OC2C (C (C (C (O2)CO)O)OC2C (C (C (C (O2)CO)O)O)O)O)O)O)O)C)C)O)C)OC1. Density: 1.59 g/cm³. ECNumber: 234-255-6. Catalog: ACM11024241. |  |
| Digitonin | Digitonin is a steroidal saponin (saraponin) obtained from the foxglove plant Digitalis purpurea. It is used as a detergent because it effectively water-solubilizes lipids. Uses: Indicators and reagents. Synonyms: β-D-Galactopyranoside, (2α, 3β, 5α, 15β, 25R)-2, 15-dihydroxyspirostan-3-yl O-β-D-glucopyranosyl-(1?3)-O-β-D-galactopyranosyl-(1?2)-O-[β-D-xylopyranosyl-(1?3)]-O-β-D-glucopyranosyl-(1?4)-; (2α, 3β, 5α, 15β, 25R)-2, 15-Dihydroxyspirostan-3-yl O-β-D-glucopyranosyl-(1?3)-O-β-D-galactopyranosyl-(1?2)-O-[β-D-xylopyranosyl-(1?3)]-O-β-D-glucopyranosyl-(1?4)-β-D-galactopyranoside; Digitogenin, 3-[O-β-D-glucopyranosyl-(1?3)-O-β-D-galactopyranosyl-(1?2)-O-[β-D-xylopyranosyl-(1?3)]-O-β-D-glucopyranosyl-(1?4)-β-D-galactopyranoside]; Digitin; NSC 23471; NSC 237417. Grades: ≥95%. CAS No. 11024-24-1. Molecular formula: C56H92O29. Mole weight: 1229.34. |  |
| β-adrenergic-receptor kinase | Requires G-protein for activation and therefore belongs to the family of G-protein-dependent receptor kinases (GRKs). Acts on the agonist-occupied form of the receptor; also phosphorylates rhodopsin, but more slowly. Does not act on casein or histones. The enzyme is inhibited by Zn2+ and digitonin but is unaffected by cyclic-AMP (cf. EC 2.7.11.14, rhodopsin kinase and EC 2.7.11.16, G-protein-coupled receptor kinase). Group: Enzymes. Synonyms: ATP:β-adrenergic-receptor phosphotransferase; [β-adrenergic-receptor] kinase; β-adrenergic receptor-specific kinase; β-AR kinase; β-ARK; β-ARK 1; β-ARK 2; β. Enzyme Commission Number: EC 2.7.11.15. CAS No. 102925-39-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3134; β-adrenergic-receptor kinase; EC 2.7.11.15; 102925-39-3; ATP:β-adrenergic-receptor phosphotransferase; [β-adrenergic-receptor] kinase; β-adrenergic receptor-specific kinase; β-AR kinase; β-ARK; β-ARK 1; β-ARK 2; β-receptor kinase; GRK2; GRK3; β-adrenergic-receptor kinase (phosphorylating); β2ARK; βARK1; β-adrenoceptor kinase; β-adrenoceptor kinase 1; β-adrenoceptor kinase 2; ADRBK1; BARK1; adrenergic receptor kinase; STK15. Cat No: EXWM-3134. |  |
| Native Bovine Cathepsin B | Cathepsin B has been found to cleave procaspase 1 and procaspase 11 and to induce apoptosis in digitonin-permeabilized cells. Translocation of cathepsin B from the cytoplasm to the nucleus contributes to bile salt induced apoptosis of Rat hepatocytes. Levels of cathepsin B in PC12 cells significantly decrease 12 to 24 hours after apoptosis is induced. Group: Enzymes. Synonyms: CTSB; cathepsin B; 9047-22-7; APPS; CPSB; cathepsin B1 (obsolete); cathepsin II. CAS No. 9047-22-7. Cathepsin B. Activity: > 10 units/mg protein. Form: Lyophilized powder containing sodium phosphate, sodium chloride and ~6% EDTA as stabilizer. Source: Bovine spleen. Species: Bovine. CTSB; cathepsin B; 9047-22-7; APPS; CPSB; cathepsin B1 (obsolete); cathepsin II. Cat No: NATE-0167. | |
| Native Human Cathepsin B | Cathepsin B has been found to cleave procaspase 1 and procaspase 11 and to induce apoptosis in digitonin-permeabilized cells. Translocation of cathepsin B from the cytoplasm to the nucleus contributes to bile salt induced apoptosis of rat hepatocytes. Levels of cathepsin B in PC12 cells significantly decrease 12 to 24 hours after apoptosis is induced. Group: Enzymes. Synonyms: CTSB; cathepsin B; cathepsin B1; APPS; CPSB; EC 3.4.22.1; 9047-22-7; cathepsin II; CatB. Enzyme Commission Number: EC 3.4.22.1. CAS No. 9047-22-7. Cathepsin B. Activity: > 2 ,000 units/mg protein (E1%/280). Storage: -20°C. Form: buffered aqueous solution. Solution in 50 mM sodium acetate, pH 5.0, with 1 mM EDTA. Source: Human liver. Species: Human. CTSB; cathepsin B; cathepsin B1; APPS; CPSB; EC 3.4.22.1; 9047-22-7; cathepsin II; CatB. Cat No: NATE-0168. | |
| rhodopsin kinase | Requires G-protein for activation and therefore belongs to the family of G-protein-dependent receptor kinases (GRKs). Acts on the bleached or activated form of rhodopsin; also phosphorylates the β-adrenergic receptor, but more slowly. Does not act on casein, histones or phosphvitin. Inhibited by Zn2+ and digitonin (cf. EC 2.7.11.15, β-adrenergic-receptor kinase and EC 2.7.11.16, G-protein-coupled receptor kinase). Group: Enzymes. Synonyms: cone opsin kinase; G-protein-coupled receptor kinase 1; GPCR kinase 1; GRK1; GRK7; opsin kinase; opsin kinase (phosphorylating); rhodopsin kinase (phosphorylating); RK; STK14. Enzyme Commission Number: EC 2.7.11.14. CAS No. 54004-64-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3133; rhodopsin kinase; EC 2.7.11.14; 54004-64-7; cone opsin kinase; G-protein-coupled receptor kinase 1; GPCR kinase 1; GRK1; GRK7; opsin kinase; opsin kinase (phosphorylating); rhodopsin kinase (phosphorylating); RK; STK14. Cat No: EXWM-3133. | |
| Sitamaquine tosylate | Sitamaquine tosylate is a dose-dependent and orally bioactive inhibitor of complex II (succinate dehydrogenase or SDH) of the respiratory chain in digitonin-permeabilized promastigotes. Sitamaquine has the potential for the treatment of life-threatening visceral leishmaniasis (VL) caused by Leishmania donovani (EC50 value 19.8 μM for L. donovani promastigotes in vitro). Synonyms: WR6026 tosylate; WR-6026 tosylate; WR 6026 tosylate. Grades: 99%. CAS No. 1019640-33-5. Molecular formula: C21H33N3O.C7H8O3S. Mole weight: 515.71. | |
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