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| Product | Description | |
|---|---|---|
| Dihydromonacolin L | Dihydromonacolin L is produced by the strain of Monascus ruber. The IC50 of HMG-CO reductase was 4.1 μmol/L. Synonyms: dihydromonacolin L lactone. CAS No. 86827-77-2. Molecular formula: C19H30O3. Mole weight: 306.44. |  |
| dihydromonacolin L hydroxylase | A heme-thiolate protein (cytochrome P-450). The dehydration of 3α-hydroxy-3,5-dihydromonacolin L acid is believed to be spontaneous. The enzyme from fungi also catalyses the reaction of EC 1.14.13.198, monacolin L hydroxylase. Group: Enzymes. Synonyms: LovA (ambiguous). Enzyme Commission Number: EC 1.14.13.197. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0797; dihydromonacolin L hydroxylase; EC 1.14.13.197; LovA (ambiguous). Cat No: EXWM-0797. |  |
| dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase | Dihydromonacolin L acid is synthesized while bound to an acyl-carrier protein domain of the lovastatin nonaketide synthase (EC 2.3.1.161). Since that enzyme lacks a thioesterase domain, release of the dihydromonacolin L acid moiety from the polyketide synthase requires this dedicated enzyme. Group: Enzymes. Synonyms: LovG. Enzyme Commission Number: EC 3.1.2.31. GUSB. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3565; dihydromonacolin L-[lovastatin nonaketide synthase] thioesterase; EC 3.1.2.31; LovG. Cat No: EXWM-3565. | |
| lovastatin nonaketide synthase | This fungal enzyme system comprises a multi-functional polyketide synthase (PKS) and an enoyl reductase. The PKS catalyses many of the chain building reactions of EC 2.3.1.85, fatty-acid synthase, as well as a reductive methylation and a Diels-Alder reaction, while the reductase is responsible for three enoyl reductions that are necessary for dihydromonacolin L acid production. Group: Enzymes. Synonyms: LNKS; LovB; LovC; acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing). Enzyme Commission Number: EC 2.3.1.161. CAS No. 235426-97-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2101; lovastatin nonaketide synthase; EC 2.3.1.161; 235426-97-8; LNKS; LovB; LovC; acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing). Cat No: EXWM-2101. | |
| monacolin L hydroxylase | A heme-thiolate protein (cytochrome P-450). The enzyme from fungi also catalyses the reaction of EC 1.14.13.197, dihydromonacolin L hydroxylase. Group: Enzymes. Synonyms: LovA (ambiguous). Enzyme Commission Number: EC 1.14.13.198. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0798; monacolin L hydroxylase; EC 1.14.13.198; LovA (ambiguous). Cat No: EXWM-0798. | |
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