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| Product | Description | |
|---|---|---|
| (11bS) -2, 6-Bis[bis[3, 5-bis (trifluoromethyl) phenyl]hydroxymethyl]-3, 5-dihydrospiro[4H-dinaphth[2, 1-c: 1', 2'-e]azepine-4, 4'-morpholinium] Bromide | (11bS) -2, 6-Bis[bis[3, 5-bis (trifluoromethyl) phenyl]hydroxymethyl]-3, 5-dihydrospiro[4H-dinaphth[2, 1-c: 1', 2'-e]azepine-4, 4'-morpholinium] Bromide. Group: Biochemicals. Grades: Highly Purified. CAS No. 1197922-04-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. US Biological Life Sciences. |  Worldwide |
| 2', 3'-Dihydrospiro [cyclopropane-1, 1'-inden]-2-amine Hydrochloride | 2', 3'-Dihydrospiro [cyclopropane-1, 1'-inden]-2-amine Hydrochloride is a building block for the preparation of fluorescent and phosphorescent phenylcycloprpane derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 1423030-97-0. Pack Sizes: 5mg, 50mg. Molecular Formula: C11H14ClN, Molecular Weight: 195.69. US Biological Life Sciences. | Worldwide |
| 2', 3'-Dihydrospiro [cyclopropane-1, 4' (1'H) -isoquinolin]-1'-one | 2', 3'-Dihydrospiro [cyclopropane-1, 4' (1'H) -isoquinolin]-1'-one is a derivative of 1-Indanone (I499900); an oxidation product of Indan (I508000) and a component of fuels, solvents, and varnishes. Group: Biochemicals. Grades: Highly Purified. CAS No. 1782267-00-8. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C11H11NO, Molecular Weight: 173.21. US Biological Life Sciences. | Worldwide |
| Drospirenone (6b,7b,15b,16b-Dimethylene-3-oxo-4-androstene-[17(b-1)-spiro-5]perhydrofuran-. 2-one, Dihydrospirorenone, Drospirenona, ZK 30595) | Synthetic progestogen exhibiting antimineralocorticoid and antiandrogenic activity. Group: Biochemicals. Alternative Names: 6b,7b,15b,16b-Dimethylene-3-oxo-4-androstene-[17(b-1)-spiro-5]perhydrofuran-2-one; Dihydrospirorenone; Drospirenona; ZK 30595. Grades: Highly Purified. CAS No. 67392-87-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| tert-Butyl 6-fluoro-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate | tert-Butyl 6-fluoro-2,3-dihydrospiro[indene-1,4'-piperidine]-1'-carboxylate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AKOS015900964, AM804977, DB-060832, I14-16014, tert-Butyl6-fluoro-2,3-dihydrospiro[indene-1,4-piperidine]-1-carboxylate, tert-butyl 6-fluoro-2,3-dihydrospiro[indene-1,4-piperidine]-1-carboxylate, 1160247-31-3. Product Category: Heterocyclic Organic Compound. CAS No. 1160247-31-3. Molecular formula: C18H24FNO2. Mole weight: 305.387063 [g/mol]. Purity: 0.96. IUPACName: tert-butyl 5-fluorospiro[1,2-dihydroindene-3,4-piperidine]-1-carboxylate. Canonical SMILES: CC(C)(C)OC(=O)N1CCC2(CCC3=C2C=C(C=C3)F)CC1. Product ID: ACM1160247313. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 10,11-Dihydro-2'-methylspiro[5h-dibenzo[a,d]cycloheptene-5,1'-[1h]isoindole]-3'(2'h)-one | 10,11-Dihydro-2'-methylspiro[5h-dibenzo[a,d]cycloheptene-5,1'-[1h]isoindole]-3'(2'h)-one. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AC1Q3XQJ, AC1MC4A3, EINECS 252-798-7, 10,11-Dihydro-2-methylspiro(5H-dibenzo(a,d)cycloheptene-5,1-(1H)isoindole)-3(2H)-one, 2-methyl-2,3-dihydrospiro[isoindole-1,2-tricyclo[9.4.0.0^{3,8}]pentadecane]-1(11),3(8),4,6,12,14-hexaen-3-one, 35926-77-3. Product Category: Heterocyclic Organic Compound. CAS No. 35926-77-3. Molecular formula: C23H19NO. Mole weight: 325.40306. Purity: 0.96. IUPACName: 2'-methylspiro[5,6-dihydrodibenzo[1,2-a:1',2'-e][7]annulene-11,3'-isoindole]-1'-one. Canonical SMILES: CN1C(=O)C2=CC=CC=C2C13C4=CC=CC=C4CCC5=CC=CC=C35. Density: 1.26g/cm³. ECNumber: 252-798-7. Product ID: ACM35926773. Alfa Chemistry ISO 9001:2015 Certified. Categories: SP5YAT3OQ4. | |
| 1'-Boc-1,2-dihydro-2-oxo-spiro[4h-3,1-benzoxazine-4,4'-piperidine] | 1'-Boc-1,2-dihydro-2-oxo-spiro[4h-3,1-benzoxazine-4,4'-piperidine]. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1'-Boc-1,2-Dihydro-2-oxo-spiro[4H-3,1-benzoxazine-4,4'-piperidine];tert-Butyl 2-oxo-1,2-dihydrospiro[benzo[d][1,3]oxazine-4,4'-piperidine]-1'-carboxylate;1,2-Dihydro-2-oxo-spiro[4H-3,1-benzoxazine-4,4'-piperidine]-1'-carboxylic acid 1,1-dimethyl ethyl est. Product Category: Heterocyclic Organic Compound. CAS No. 84060-08-2. Molecular formula: C17H22N2O4. Mole weight: 318.371. Purity: 0.96. IUPACName: tert-butyl 2-oxospiro[1H-3,1-benzoxazine-4,4-piperidine]-1-carboxylate. Canonical SMILES: CC(C)(C)OC(=O)N1CCC2(CC1)C3=CC=CC=C3NC(=O)O2. Density: 1.25g/cm³. Product ID: ACM84060082. Alfa Chemistry ISO 9001:2015 Certified. | |
| 1'-Boc-6-fluoro-1,2-dihydro-2-oxospiro[4h-3,1-benzoxazine-4,4'-piperidine] | 1'-Boc-6-fluoro-1,2-dihydro-2-oxospiro[4h-3,1-benzoxazine-4,4'-piperidine]. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1'-Boc-6-Fluoro-1,2-dihydro-2-oxospiro[4H-3,1-benzoxazine-4,4'-piperidine];tert-Butyl 6-fluoro-2-oxo-1,2-dihydrospiro[benzo[d][1,3]oxazine-4,4'-piperidine]-1'-carboxylate. Product Category: Heterocyclic Organic Compound. CAS No. 345938-08-1. Molecular formula: C17H21FN2O4. Mole weight: 336.361. Purity: 0.96. IUPACName: tert-butyl 6-fluoro-2-oxospiro[1H-3,1-benzoxazine-4,4-piperidine]-1-carboxylate. Canonical SMILES: CC(C)(C)OC(=O)N1CCC2(CC1)C3=C(C=CC(=C3)F)NC(=O)O2. Density: 1.3g/cm³. Product ID: ACM345938081. Alfa Chemistry ISO 9001:2015 Certified. | |
| (1R, 2R, 3R) -3- [N- (4-Methoxybenzyl) imido methyl thiomethoxy] -1, 2-dihydroxy-4-cyclopropene 1,2-Cyclohexyl Ketal | Mannostatin intermediate. Group: Biochemicals. Alternative Names: (1R, 2R, 3R) - [ (4-Methoxyphenyl) methyl] carbonimidothioic Acid O- (3'a, 6'a-Dihydrospiro [cyclohexane-1, 2'- [4H]cyclopenta [1, 3]dioxol]-4'-yl) S-Methyl Ester. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 6'-Fluoro-2',3'-dihydro-2H,5H-spiro[imidazolidine-4,4'-thiochromene]-2,5-dione 1',1'-dioxide | 6'-Fluoro-2',3'-dihydro-2H,5H-spiro[imidazolidine-4,4'-thiochromene]-2,5-dione 1',1'-dioxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ZINC02635396, CID2098019, 66892-63-5. Product Category: Heterocyclic Organic Compound. CAS No. 66892-63-5. Molecular formula: C11H9FN2O4S. Mole weight: 284.263563 [g/mol]. Purity: 0.96. IUPACName: (4R)-6-fluoro-1,1-dioxospiro[2,3-dihydrothiochromene-4,5-imidazolidine]-2,4-dione. Canonical SMILES: C1CS(=O)(=O)C2=C(C13C(=O)NC(=O)N3)C=C(C=C2)F. Density: 1.68g/cm³. Product ID: ACM66892635. Alfa Chemistry ISO 9001:2015 Certified. Categories: 6-fluoro-2,3-dihydrospiro[1lambda6-benzothiopyran-4,4'-imidazolidine]-1,1,2',5'-tetrone. | |
| 8a-oxo-eprinomectin B1a | 8a-oxo-eprinomectin B1a is an impurity of eprinomectin, a broad-spectrum endectocide used to control various species and stages of internal and external parasites. Synonyms: N-[(3S,4S,6S)-6-{[(3S,4S,6R)-6-{[(1R,2'R,2R,3'S,5R,6'S,8S,12R,14E,16S,17S,18E,20Z,24S)-2'-[(2S)-but-2-yl]-2,24-dihydroxy-3,3',15,17-tetramethyl-6,22-dioxo-2',3'-dihydrospiro[7,11,23-trioxatetracyclo[19.2.1.18,12.05,24]pentacosa-3,14,18,20-tetraene-10,6'-pyran]-16-yl]oxy}-4-methoxy-2-methyl-3,4,5,6-tetrahydro-2H-pyran-3-yl]oxy}-4-methoxy-2-methyl-3,4,5,6-tetrahydro-2H-pyran-3-yl]acetamide. Molecular formula: C50H73NO15. Mole weight: 928.13. |  |
| A-485 | A-485 is a potent and selective HAT inhibitor of p300/CBP in vitro with an IC50 of 10 nM in a p300 TR-FRET assay and 3 nM in a CBP TR-FRET assay with selectivity > 1000-fold over closely related HATs. SPR data indicates potent binding to p300 (KD=15 nM). In PC-3 cells A-485 reduces H3K27ac with IC50 of 73 nM while not affecting H3K9ac levels. Inhibition of cellular proliferation is observed in several cancer cell types, most notably AR+ prostate, multiple myeloma, and NHL. A-486 is a suitable control with 1000-fold higher IC50 in the p300 TR-FRET assay. Uses: Designed for use in research and industrial production. Additional or Alternative Names: A-485; A 485; A485. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1889279-16-6. Molecular formula: C25H24F4N4O5. Mole weight: 536.48. Purity: >98%. IUPACName: N-(4-fluorobenzyl)-2-((R)-5-(3-methylureido)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-3'-yl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide. Canonical SMILES: O=C(N1CC(N([C@H](C(F)(F)F)C)CC2=CC=C(F)C=C2)=O)[C@@]3(OC1=O)CCC4=CC(NC(NC)=O)=CC=C43. Product ID: ACM1889279166. Alfa Chemistry ISO 9001:2015 Certified. Categories: A485 road. | |
| CBP/p300-IN-12 | CBP/p300-IN-12 is a potent and selective covalent histone acetyltransferases p300 (IC50 = 166 nM) and CBP inhibitor that reduces H3K27Ac levels in PC-3 cells (EC50 = 37 nM). CBP/p300-IN-12 forms a covalent adduct with C1450. Synonyms: N-(3-(3-((R)-3'-(2-((4-fluorobenzyl)((S)-1,1,1-trifluoropropan-2-yl)amino)-2-oxoethyl)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-5-yl)ureido)phenyl)acrylamide. Molecular formula: C33H29F4N5O6. Mole weight: 667.61. | |
| CBP/p300-IN-5 | P300/CBP-IN-5 is a potent inhibitor of p300/CBP histone acetyltransferase with an IC50 of 18.8 nM. (Extracted from patent WO2016044770A1, Example 715). Synonyms: CBP/p300-IN-5; 2-[4-[(3'R,4S)-3'-fluoro-1-[2-[(4-fluorophenyl)methyl-[(1S)-2,2,2-trifluoro-1-methyl-ethyl]amino]-2-oxo-ethyl]-2,5-dioxo-spiro[imidazolidine-4,1'-indane]-5'-yl]pyrazol-1-yl]-N-methylacetamide; 2-((3'R,4S)-3'-Fluoro-5'-(1-(2-(methylamino)-2-oxoethyl)-1H-pyrazol-4-yl)-2,5-dioxo-2',3'-dihydrospiro[imidazolidine-4,1'-inden]-1-yl)-N-(4-fluorobenzyl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide; N-(4-Fluorobenzyl)-2-[(3'R,4S)-3'-fluoro-5'-{1-[2-(methylamino)-2-oxoethyl]-1H-pyrazol-4-yl}-2,5-dioxo-2',3'-dihydro-1H-spiro[imidazolidine-4,1'-inden]-1-yl]-N-[(2S)-1,1,1-trifluoro-2-propanyl]acetamide. Grade: ≥95%. CAS No. 1889284-33-6. Molecular formula: C29H27F5N6O4. Mole weight: 618.55. | |
| Drospirenone | Drospirenone (Dihydrospirorenone) is an orally active fourth-generation progestin that interacts with the progesterone receptor (PR) and androgen receptor (AR). Drospirenone significantly decreases both plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator (tPA) via the AR. Drospirenone can produce DNA damage in bone marrow cells of female mice. [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Dihydrospirorenone. CAS No. 67392-87-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0111. |  |
| Drospirenone | Drospirenone is a synthetic hormone used in birth control pills and postmenopausal hormone replacement therapy pills. Synonyms: Drospirenone; dihydrospirorenone; drospirenone; ZK 3059; ZK30595; 67392-87-4; Drospirenona; Drospirenonum; Dehydrospirorenone. Grade: >98%. CAS No. 67392-87-4. Molecular formula: C24H30O3. Mole weight: 366.49. | |
| Drospirenone | Drospirenone. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ZK 3059; 6b,7b; dihydrospirorenone; arbolactone; Drospirenona; Drospirenone; Dorospirenone; Drospirenon. Product Category: Steroidal Compounds. Appearance: white to off-white crystalline powder. CAS No. 67392-87-4. Molecular formula: C24H30O3. Mole weight: 366.49. Purity: 0.98. IUPACName: drospirenone. Canonical SMILES: CC12CCC(=O)C=C1C3CC3C4C2CCC5(C4C6CC6C57CCC(=O)O7)C. Density: 1.26 g/cm³. ECNumber: 266-679-2. Product ID: ACM67392874. Alfa Chemistry ISO 9001:2015 Certified. | |
| Drospirenone-d4 | Labeled Drospirenone. Synthetic progestogen exhibiting antimineralocorticoid and antiandrogenic activity. Group: Biochemicals. Alternative Names: 6 β,7 β,15 β,16 β-Dimethylene-3-oxo-4-androstene-[17( β-1)-spiro-5]perhydrofuran-2-one-d4; Dihydrospirorenone-d4; Drospirenona-d4; ZK 30595-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| GB 83 | GB 83 is a selective antagonist of human protease activated receptor 2 (PAR2) (IC50 = 2 mM). Synonyms: GB83; GB 83; GB-83; N-((S)-3-Cyclohexyl-1-((2S,3S)-1-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)-3-methyl-1-oxopentan-2-ylamino)-1-oxopropan-2-yl)isoxazole-5-carboxamide. Grade: 99%. CAS No. 1252806-86-2. Molecular formula: C32H44N4O4. Mole weight: 548.72. | |
| HAT-IN-1 | HAT-IN-1 is an inhibitor of HAT, used in cancer research. Synonyms: 2-(5'-Bromo-2,3',5-trioxo-2',3'-dihydro-1H-spiro[imidazolidine-4,1'-inden]-1-yl)-N-(4-fluorobenzyl)-N-[(2S)-1,1,1-trifluoro-2-propanyl]acetamide; Spiro[imidazolidine-4,1'-[1H]indene]-1-acetamide, 5'-bromo-N-[(4-fluorophenyl)methyl]-2',3'-dihydro-2,3',5-trioxo-N-[(1S)-2,2,2-trifluoro-1-methylethyl]-; 2-(5'-Bromo-2,3',5-trioxo-2',3'-dihydrospiro[imidazolidine-4,1'-inden]-1-yl)-N-(4-fluorobenzyl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide. CAS No. 1889281-94-0. Molecular formula: C23H18BrF4N3O4. Mole weight: 556.30. | |
| Illudin S | Illudin S is a fungal sesquiterpene that, through their unique DNA alkylating actions, have anticancer potential. Illudin S is a cytotoxic illudin that is converted, intracellularly, to metabolites that cause a complete block of cell cycling at the G1-S phase interface, particularly in myeloid and T-lymphocyte leukemia cells (IC50 = 6-11 nM). T-lymphocyte leukemia CEM cells that are resistant to doxorubicin (Item No. 15007), epipodophyllotoxins, and 1-β-D-arabinofuranosylcytosine display only 2-fold increased resistance to illudin S. Illudin S metabolites induce DNA damage that is not repaired by the processes that counter conventional DNA alkylating agents. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Illudin S; DR-15978; DR 15978; DR15978; NSC 626369; NSC-626369; NSC626369; Lunamycin; Lampterol. Product Category: Others. Appearance: Solid powder. CAS No. 1149-99-1. Molecular formula: C15H20O4. Mole weight: 264.32. Purity: 0.98. IUPACName: (2'S,3'R,6'R)-3',6'-dihydroxy-2'-(hydroxymethyl)-2',4',6'-trimethyl-2',3'-dihydrospiro[cyclopropane-1,5'-inden]-7'(6'H)-one. Canonical SMILES: CC1=C2[C@H]([C@](CO)(C=C2C([C@](O)(C13CC3)C)=O)C)O. Product ID: ACM1149991. Alfa Chemistry ISO 9001:2015 Certified. | |
| Spiro[cyclohexane-1,3'-[3h]indol]-2'(1'h)-one,5'-bromo- | Spiro[cyclohexane-1,3'-[3h]indol]-2'(1'h)-one,5'-bromo-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 304468-42-6, 5-BROMOSPIRO[CYCLOHEXANE-1,3-INDOLIN]-2-ONE, 5-bromo-1,2-dihydrospiro[cyclohexane-1,3-indole]-2-one, SureCN61843, AGN-PC-009RZ0, CTK4G5214, MolPort-008-696-820, ZINC40448519, AKOS005073422, AG-L-22860, LD-0097, MCULE-7462432173, RP15463, AK-29117, FT-0646109, EN300-79335, 5-Bromospiro[cyclohexane-1,3-indol]-2(1H)-one, 5-bromo-1H-spiro[cyclohexane-1,3-indole]-2-one, Spiro[cyclohexane-1,3-[3H]indol]-2(1H)-one, 5-bromo-, Spiro[cyclohexane-1,3-[3H]indol]-2(1H)-one,5-bromo-. Product Category: Heterocyclic Organic Compound. CAS No. 304468-42-6. Molecular formula: C13H14BrNO. Mole weight: 280.17. Purity: 0.96. IUPACName: 5-bromospiro[1H-indole-3,1-cyclohexane]-2-one. Canonical SMILES: C1CCC2(CC1)C3=C(C=CC(=C3)Br)NC2=O. Density: 1.512g/cm³. Product ID: ACM304468426. Alfa Chemistry ISO 9001:2015 Certified. Categories: 5'-bromo-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one. | |
| Spiro[indoline-3,4'-piperidine] | Spiro[indoline-3,4'-piperidine]. Group: Biochemicals. Alternative Names: 1,2-Dihydrospiro[3H-indole-3,4'-piperidine]. Grades: Highly Purified. CAS No. 171-75-5. Pack Sizes: 250mg. Molecular Formula: C12H16N2, Molecular Weight: 188.27. US Biological Life Sciences. | Worldwide |
| tert-Butyl 3-amino-2,3-dihydro-1'h-spiro[indene-1,4'-piperidine]-1'-carboxylate | tert-Butyl 3-amino-2,3-dihydro-1'h-spiro[indene-1,4'-piperidine]-1'-carboxylate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: TERT-BUTYL 3-AMINO-2,3-DIHYDROSPIRO[INDENE-1,4'-PIPERIDINE]-1'-CARBOXYLATE;3-AMINO-4'-N-BOC-SPIRO-INDANE-PIPERIDINE;TERT-BUTYL 3-AMINO-2,3-DIHYDRO-1'H-SPIRO[INDENE-1,4'-PIPERIDINE]-1'-CARBOXYLATE. Product Category: Heterocyclic Organic Compound. CAS No. 185527-11-1. Molecular formula: C18H26N2O2. Mole weight: 302.41124. Product ID: ACM185527111. Alfa Chemistry ISO 9001:2015 Certified. | |
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