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Dihydrotachysterol is a synthetic analog of vitamin D. Dihydrotachysterol can be used to for the research of hypocalcemia (lack of calcium in the blood) and hypoparathyroidism (lack of parathyroid hormone in the body) [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 67-96-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-A0245.
Dihydrotachysterol
Dihydrotachysterol is a vitamin D that can be regarded as a reduction product of vitamin D2 activated in the liver. It does not require renal hydroxylation like vitamin D2 and vitamin D3. It could stimulate intestinal calcium absorption and increases renal phosphate excretion. It is widely used for hypocalcemic hypoparathyroidism following surgical removal of parathyroids. Synonyms: HSDB 3314; Hytakerol; Parterol; Tachyrol; Dihydral; (1S,3E,4S)-4-Methyl-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-7a-methyl-1-[(1R,2E,4R)-1,4,5-trimethyl-2-hexen-1-yl]-4H-onden-4-ylidene]ethylidene]cyclohexanol; (3β,5E,7E,10α,22E)-9,10-Secoergosta-5,7,22-trien-3-ol; 24-Methyl-9,10-secocholesta-5,7,22-trien-3β-ol; Antitanil; Calcamine; DHT2; Dichystrolum; Dihidrotaquisterol; (5E,7E,22E)-(3S,10S)-9,10-seco-5,7,22-ergostatrien-3-ol. Grades: 98%. CAS No. 67-96-9. Molecular formula: C28H46O. Mole weight: 398.66.
Dihydrotachysterol (DHT) is a synthetic vitamin D analog activated in the liver that does not require renal hydroxylation like vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). DHT has a rapid onset of action (2 hours), a shorter half-life, and a greater effect on mineralization of bone salts than does vitamin D. The half synthetic Vitamin D analogue dihydrotachysterol (DHT) is widely used for hypocalcaemic hypoparathyroidism following surgical removal of parathyroids. Such treatment generally initiated by surgeons right after surgery has to be continued in clinical practice. Unfortunately, the required careful monitoring of calcium metabolism is often lacking and as demonstrated may lead to life-threatening conditions. In comparison to short acting vitamin-D derivates hypercalcaemic episodes with DHT appear to last longer and may therefore occur with higher incidence. Group: Biochemicals. Alternative Names: (1S, 3E, 4S) -4-Methyl-3- [ (2E) -2- [ (1R, 3aS, 7aR) -octahydro-7a-methyl-1- [ (1R, 2E, 4R) -1, 4, 5-trimethyl-2-hexen-1-yl] -4H-onden-4-ylidene] ethylidene] cyclohexanol; (3 β, 5E, 7E, 10α, 22E)-9, 10-Secoergosta-5, 7, 22-trien-3-ol; 24-Methyl-9,10-secocholesta-5,7,22-trien-3 β-ol; Antitanil; Calcamine; DHT2; Dichystrolum; Dihydral; Tachyrol. Grades: Highly Purified. CAS No. 67-96-9. Pack Sizes: 10mg, 25mg, 50mg. Molecular Formula: C??H??O, Molecular Weight: 398.66. US Biological Life Sciences.
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