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1,6-Dimethanesulfonate-D-mannitol is a reagent used in the preparation of pharmaceutical compounds for tumor diagnosis and treatment. Group: Biochemicals. Grades: Highly Purified. CAS No. 1187-00-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H18O10S2, Molecular Weight: 338.35. US Biological Life Sciences.
(1R,2R)-1,2-Cyclohexanedimethanol 1,2-Dimethanesulfonate. Group: Biochemicals. Alternative Names: (1R-trans)-1,2-Cyclohexanedimethanol Dimethanesulfonate; (1R, 2R) -1, 2-Bis (methanesulfonyloxy methyl ) cyclohexane; (1R, 2R) -1, 2-Bis (methanesulfonyloxy methyl ) cyclohexan. Grades: Highly Purified. CAS No. 186204-35-3. Pack Sizes: 25mg. US Biological Life Sciences.
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2,?2'-?Sulfonylbis-?ethanol Dimethanesulfonate
2,?2'-?Sulfonylbis-?ethanol Dimethanesulfonate is an intermediate in synthesizing Bis (methylsulfinylethyl) sulfone (B494850), a sulfur mustard metabolite found in urine. Group: Biochemicals. Grades: Highly Purified. CAS No. 53629-52-0. Pack Sizes: 25mg, 50mg. Molecular Formula: C6H14O8S3. US Biological Life Sciences.
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3,5-Dimethanesulfonate Thymidine, Methyl-d3
3,5-Dimethanesulfonate Thymidine, Methyl-d3. Group: Biochemicals. Alternative Names: 1-(2-Deoxy-3,5-dimethanesulfonyl- β-D-threopentosyl)-thymine-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Diethylene Glycol Dimethanesulfonate
Intermediate in the production of alkylating agents. Group: Biochemicals. Alternative Names: 2,2'-Oxybis-ethanol 1,1'-Dimethanesulfonate; 2,2'-Oxybis-ethanol Dimethanesulfonate; Bis(2-mesyloxyethyl) Ether; Diethylene Glycol Dimesylate; ENT 61168. Grades: Highly Purified. CAS No. 34604-52-9. Pack Sizes: 5g. US Biological Life Sciences.
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Ethylene dimethanesulfonate
Ethylene dimethane sulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol. Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 4672-49-5. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-129524.
GDC-0941 dimethanesulfonate
GDC-0941 dimethanesulfonate is a potent inhibitor of PI3Kα/δ with modest selectivity against p110β and p110&gamma. It is a novel selective class I phosphatidylinositol-3-kinase (PI3K) inhibitor. It is designed to bind the ATP-binding pocket of PI3K and to prevent formation of phosphatidylinositol-3, 4, 5-triphosphate (PIP3), a second messenger that transmits PI3K downstream signals. It causes growth inhibition in a variety of cancer cell lines, including A2780, MDA-MB-361, PC3, and U87MG. It also inhibits the growth of trastuzumab-sensitive and -resistant HER2-amplied cancer cells which harbor p110( mutations or PTEN loss. It also reduces tumor volume in different xenograft models. Synonyms: GDC-0941 dimethanesulfonate; GDC 0941 dimethanesulfonate; GDC0941 dimethanesulfonate; Pictilisib dimethanesulfonate; GDC-0941 (2 MeSO3H salt). Grades: >98%. CAS No. 957054-33-0. Molecular formula: C25H35N7O9S4. Mole weight: 705.85.
Heptamidine dimethanesulfonate
Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) is a potent Pentamidine-related inhibitor of the calcium-binding protein S100B ( K d =6.9 μM), selectively kills melanoma cells with S100B over those without S100B [1]. Heptamidine is a useful tool for the investigation of Myotonic dystrophy (DM) [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SBi4211 dimethanesulfonate. CAS No. 161374-55-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16918A.
MK-142 dimethanesulfonate
MK-142 is a bioactive agent with antiarrhythmic properties with its content in the skeletal muscles indicates a high affinity of the examined substance to the heart muscle. Uses: Antiarrhytmic. Synonyms: MK142; MK-142; MK 142; 3,3'-(ethane-1,2-diylbis(azanediyl))bis(1-(4-methoxyphenoxy)propan-2-ol). Grades: ≥95%. CAS No. 42794-63-8. Molecular formula: C22H32N2O6. Mole weight: 420.50.
Intermediate in the production of alkylating agents. Group: Biochemicals. Alternative Names: 3,6,9,12-Tetraoxatetradecane-1,14-diol 1,14-Dimethanesulfonate; Pentaethylene Glycol Dimesylate. Grades: Highly Purified. CAS No. 109789-39-1. Pack Sizes: 500mg. US Biological Life Sciences.
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Pictilisib dimethanesulfonate
Pictilisib dimethanesulfonate (GDC-0941 dimethanesulfonate) is a potent inhibitor of PI3Kα/δ with IC 50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0941 dimethanesulfonate; GDC-0941 2 MeSO3H salt. CAS No. 957054-33-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-20180.
Triethylene Glycol Dimethanesulfonate
Intermediate in the production of alkylating agents. Group: Biochemicals. Alternative Names: 2,2'-[1,2-Ethanediylbis(oxy)]bis-ethanol 1,1'-Dimethanesulfonate; Dimesyl Triethylene Glycol; Triethylene Glycol Dimesylate. Grades: Highly Purified. CAS No. 80322-82-3. Pack Sizes: 1g. US Biological Life Sciences.
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1,2-Ethanediyl bismethane thiosulfonate
1,2-Ethanediyl bismethane thiosulfonate. Group: Biochemicals. Alternative Names: 1,2-Ethanedithiol dimethanesulfonate; Preparation 289. Grades: Highly Purified. CAS No. 55-95-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C4H10O4S4. US Biological Life Sciences.
1,2-O-Isopropylidine-3-O-(4-methoxybenzyl)-5-O-methylsulfonyl-4-C-methylsulfonyloxymethyl-a-D-ribofuranose is primarily used in the biomedical field with inherent anti-inflammatory and antiviral properties. Its involvement in antiretroviral drugs research and development. Synonyms: SCHEMBL133350; ((3aR,6S,6aR)-6-((4-Methoxybenzyl)oxy)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole-5,5-diyl)bis(methylene) dimethanesulfonate; 501012-17-5. CAS No. 501012-17-5. Molecular formula: C19H28O11S2. Mole weight: 496.54.
(-)-2,3-O-Isopropylidene-L-threitol-1,4-dimethane sulfonate stands as a cornerstone in the biomedical realm. It exerts its significance in the synthesis of an array of medicinal agents and pharmaceutics. Synonyms: [(4s,5s)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]dimethanediyl dimethanesulfonate; [(4S,5S)-2,2-dimethyl-5-(methylsulfonyloxymethyl)-1,3-dioxolan-4-yl]methyl methanesulfonate; (-)-2,3-O-Isopropylidene-L-threitol-1,4-dimethane sulfonate; (-)-2,3-O-ISOPROPYLIDENE-L-THREITOL 1,4-DIMETHANE SULFONATE; NSC60499; 1,3-Dioxolane-4,5-dimethanol,2,2-dimethyl-, 4,5-dimethanesulfonate, (4S,5S)-1111. CAS No. 4248-74-2. Molecular formula: C9H18O8S2. Mole weight: 318.37.
a,a'-Paraxylyl bismethane thiosulfonate
a,a'-Paraxylyl bismethane thiosulfonate. Group: Biochemicals. Alternative Names: Thio-methanesulfonic acid S,S'-p-phenylenedimethylene ester; p-Xylene-a,a'-dithiol dimethanesulfonate. Grades: Highly Purified. CAS No. 3948-46-7. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C10H14O4S4. US Biological Life Sciences.
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Almitrine dimesylate
Almitrine dimesylate is the dimethanesulfonate salt of almitrine. It acts as an agonist of peripheral chemoreceptors located on the carotid bodies, thereby stimulating respiratory system. Synonyms: Almitrine mesylate; Almitrine bismesylate; Almitrine dimethanesulfonate; Vectarion. Grades: 95%. CAS No. 29608-49-9. Molecular formula: C26H29F2N7.2(CH4O3S). Mole weight: 669.764.
Betahistine mesylate
Betahistine is a structural analog of histamine that acts as a weak partial postsynaptic histamine H1 receptor agonist and presynaptic H3 receptor antagonist, with no effect on postsynaptic H2 receptors. Betahistine, sold under the brand name Serc among others, is an anti-vertigo medication. It is commonly prescribed for balance disorders or to alleviate vertigo symptoms, e.g. those associated with Ménière's disease. Uses: Vasodilator agents. Synonyms: N-methyl-2-pyridineethanamine methanesulfonate (1:2); N-methyl-2-pyridineethanamine Dimethanesulfonate; Merislon. Grades: ≥98%. CAS No. 54856-23-4. Molecular formula: C8H12N2·2CH4O3S. Mole weight: 328.41.
Busulfan
Alkylating agent with antileukemic activity. Antineoplastic. Group: Biochemicals. Alternative Names: 1,4-Butanediol-dimethanesulfonate Esters; Busulphan; CB-2041; GT-41; Busulfex; Misulban; Myleran. Grades: Highly Purified. CAS No. 55-98-1. Pack Sizes: 100mg. US Biological Life Sciences.
Alkylating agent with antileukemic activity. Antineoplastic. Group: Biochemicals. Alternative Names: 1,4-Butanediol-d8-dimethanesulfonate Esters; Busulphan-d8; CB-2041-d8; GT-41-d8; Busulfex-d8; Misulban-d8; Myleran-d8. Grades: Highly Purified. CAS No. 116653-28-2. Pack Sizes: 2.5mg, 10mg. US Biological Life Sciences.
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Busulfan-d8
Heterocyclic Organic Compound. Alternative Names: BUSULFAN-D8 (TETRAMETHYLENE-D8);Busulfan-D8(tetramethylene);1,4-Butanediol-d8-dimethanesulfonate Esters;Busulfan-d8;Busulfex-d8;Busulphan-d8;CB-2041-d8;GT-41-d8. CAS No. 116653-28-2. Molecular formula: C6H6D8O6S2. Mole weight: 254.35. Appearance: White Solid. Purity: 99 atom % D. Catalog: ACM116653282.
Ecamsule.2Na
Ecamsule protect the skin from sunburn and erythema. It causes serious eye damage, so please wear protective gloves/protective clothing/eye protection/face protection. Uses: Sunscreening agents. Synonyms: Sodium ((1, 4-phenylenebis(methanylylidene))bis(7, 7-dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl-3-ylidene))dimethanesulfonate. Grades: ≥ 95.0%. CAS No. 90458-75-6. Molecular formula: C28H32Na2O8S2. Mole weight: 606.66.
Edoxaban Impurity 6
Edoxaban Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N1-((1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide dimethanesulfonate. Molecular Formula: C16H22ClN5O3·2CH4O3S. Mole Weight: 560.05. Catalog: APB01965.
Efinaconazole Impurity 30
Efinaconazole Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diyl dimethanesulfonate. CAS No. 153522-54-4. Molecular Formula: C14H17F2N3O6S2. Mole Weight: 425.43. Catalog: APB153522544.
GZD824 Dimesylate
GZD824 Dimesylate is a novel orally bioavailable Bcr-Abl inhibitor for Bcr-Abl(WT) and Bcr-Abl(T315I) with IC50 of 0.34 nM and 0.68 nM, respectively. Synonyms: Olverembatinib dimesylate; HQP1351 dimesylate; GZD 824 Dimesylate; GZD-824 Dimesylate; 3-((1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamide dimethanesulfonate; Benzamide, 4-methyl-N-(4-((4-methyl-1-piperazinyl)methyl)-3-(trifluoromethyl)phenyl)-3-(2-(1H-pyrazolo(3,4-b)pyridin-5-yl)ethynyl)-, methanesulfonate (1:2). Grades: ≥99%. CAS No. 1421783-64-3. Molecular formula: C29H27F3N6O.2CH4O3S. Mole weight: 724.77.
INCB 3284
INCB 3284 is a potent, selective and orally bioavailable CCR2 antagonist with IC50 of 3.7 nM. Synonyms: N-(2-(((R)-1-((1r,4R)-4-hydroxy-4-(6-methoxypyridin-3-yl)cyclohexyl)pyrrolidin-3-yl)amino)-2-oxoethyl)-3-(trifluoromethyl)benzamide dimethanesulfonate; INCB3284; INCB 3284; INCB-3284; INCB3284 mesylate; INCB3284 dimesylate. CAS No. 887401-92-5. Molecular formula: C26H31F3N4O4. Mole weight: 520.54.
INCB 3284 dimesylate
INCB 3284 dimesylate is a potent, selective and orally bioavailable CCR2 antagonist with IC50 of 3.7 nM. Synonyms: INCB 3284 dimesylate; INCB3284 dimesylate; INCB-3284 dimesylate; N-[2-[[(3R)-1-[trans-4-hydroxy-4-(6-methoxy-3-pyridinyl)cyclohexyl]-3-pyrrolidinyl]amino]-2-oxoethyl]-3-(trifluoromethyl)-benzamide, dimethanesulfonate. CAS No. 887401-93-6. Molecular formula: C26H31F3N4O4.2CH4O3S. Mole weight: 712.76.
IPD Hydrochloride
IPD is an alkylsulfonate DNA crosslinker. Uses: Dna crosslinker. Synonyms: Improsulfan hydrochloride, Improsulfan HCl, Yoshi-864; Yoshi 864; Yoshi864; NSC102627; NSC-102627; NSC 102627azanediylbis(propane-3,1-diyl) dimethanesulfonate hydrochloride; 3-(3-methylsulfonyloxypropylamino)propyl methanesulfonate;hydrochloride. Grades: ≥98%. CAS No. 3458-22-8. Molecular formula: C8H20ClNO6S2. Mole weight: 325.82.
Ipexidine mesylate
Ipexidine mesylate is a bio-active chemical compound. Synonyms: Urea, N,N''-(1,4-Piperazinediylbis(3,1-propanediyliminocarbonimidoyl)bis(N'-hexyl-, dimethanesulfonate; CK-0569; Guanidino propyl piperazine. Grades: 98%. CAS No. 69017-90-9. Molecular formula: C28H62N10O8S2. Mole weight: 730.98.
Lurasidone impurity 38
Lurasidone impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1S,2S)-cyclohexane-1,2-diylbis(methylene) dimethanesulfonate. CAS No. 173658-50-9. Molecular Formula: C10H20O6S2. Mole Weight: 300.39. Catalog: APB173658509.
Lurasidone impurity 39
Lurasidone impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2S)-cyclohexane-1,2-diylbis(methylene) dimethanesulfonate. CAS No. 66347-68-0. Molecular Formula: C10H20O6S2. Mole Weight: 300.39. Catalog: APB66347680.
LY2228820
LY2228820. Group: Biochemicals. Alternative Names: 5-[2-(1,1-Dimethylethyl)-5-(4-fluorophenyl)-1H-imidazol-4-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate. Grades: Highly Purified. CAS No. 862507-23-1. Pack Sizes: 2mg, 5mg, 10mg, 25mg, 50mg. Molecular Formula: C26H37FN6O6S2. US Biological Life Sciences.
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Nafamostat hydrochloride
Nafamostat hydrochloride is a synthetic serine protease inhibitor. It is used as an anticoagulant. It is similar to Tranilast. Uses: Nafamostat hydrochloride is used as an anticoagulant. Synonyms: Benzoic acid,4-[(aminoiminomethyl)amino]-,6- (aminoiminomethyl)-2-naphthalenyl ester,dihydrochloride;Nafamostat mesylate dihydrochloride;6-Amidino-2-naphthyl p-guanidinobenzoate dimethanesulfonate dihydrochloride. Grades: >98%. CAS No. 80251-32-7. Molecular formula: C19H19N5O2Cl2. Mole weight: 420.29.
Nafamostat mesilate
Nafamostat Mesylate is a synthetic serine protease inhibitor and an anticoagulant. It is a fast-acting proteolytic inhibitor and used during hemodialysis to prevent the proteolysis of fibrinogen into fibrin. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: 6-Amidino-2-naphthyl 4-guanidinobenzoate dimethanesulfonate; Nafamostat mesylate; nafamostat mesilate; FUT-175; FUT 175; FUT175. Grades: >98%. CAS No. 82956-11-4. Molecular formula: C21H25N5O8S2. Mole weight: 539.58.
NAS-181
NAS-181 is a 5-HT1B receptor antagonist with Ki value of 47 nM. It can increase synthesis and metabolism of 5-HT in the brain following systemic administration and improve passive avoidance retention performance in vivo. Synonyms: NAS-181; NAS 181; NAS181; (2R)-2-[[[3-(4-Morpholinylmethyl)-2H-1-benzopyran-8-yl]oxy]methyl]morpholine dimethanesulfonate. Grades: ≥97% by HPLC. CAS No. 1217474-40-2. Molecular formula: C19H26N2O4.2CH3SO3H. Mole weight: 538.63.
Necrox-5 (methanesulfonate)
Necrox-5 is a cell permeable necrosis inhibitor with the antioxidant and cardioprotective effects. It localizes mainly in the mitochondria that selectively blocks oxidative stress-induced necrotic cell death (0.1μM NecroX-5 prevented ~50% cell death in H9C2 cells exposed to 400μM t-BuOOH for 2 hours LDH assay used). Necrox-5 was demonstrated that protect cells from oxidative stress, hypoxia, cold shock, CCl4-induced liver injury and chronic liver fibrosis. Uses: A cell permeable necrosis inhibitor with the antioxidant and cardioprotective effects. Synonyms: NecroX-5 mesylate; 5-[(1,1-dioxido-4-thiomorpholinyl)methyl]-2-phenyl-N-[(tetrahydro-2H-pyran-4-yl)methyl]-1H-indol-7-amine dimethanesulfonate; Necrosis Inhibitor 5; 1H-Indol-7-amine, 5-[(1,1-dioxido-4-thiomorpholinyl)methyl]-2-phenyl-N-[(tetrahydro-2H-pyran-4-yl)methyl]-, methanesulfonate (1:2). Grades: ≥98%. CAS No. 1383718-29-3. Molecular formula: C25H31N3O3S.2CH4O3S. Mole weight: 645.81.
NSC 109555
NSC 109555. Group: Biochemicals. Alternative Names: 4,4'-Diacetyldiphenylurea bis(guanylhydrazone) Bismethanesulfonate; 2, 2'- [Carbonyl bis (imino-4, 1-phenyl ene ethyl idyne ) ] bis-hydrazinecarboximidam ide Dimethanesulfonate. Grades: Highly Purified. CAS No. 15427-93-7. Pack Sizes: 10mg. Molecular Formula: C21H32N10O7S2, Molecular Weight: 600.669999999999. US Biological Life Sciences.
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NSC 109555 dimesylate
NSC 109555 is a potent and selective inhibitor of checkpoint kinase 2 (Chk2), displaying no effect against other kinases. It inhibits H1 phosphorylation and attenuates mitochondrial ATP synthesis. NSC 109555 can be used in cancer therapy. Synonyms: DDUG; NCI C04808; Carbanilide, 4,4'-diacetyl-, 4,4'-bis(amidinohydrazone), dimethanesulfonate. CAS No. 15427-93-7. Molecular formula: C19H24N10O·2CH3SO3H. Mole weight: 600.7.
Prochlorperazine-d3 Dimesylate
Antiemetic, antipsychotic; used in treatment of vertigo. Group: Biochemicals. Alternative Names: 2-Chloro-10-[3-(4-methyl-d3-1-piperazinyl)propyl]-10H-phenothiazine Dimethanesulfonate; 3-Chloro-10-[3- (4-methyl-d3-1-piperazinyl) propyl]phenothiazine Dimesylate; Novamin-d3; Tementyl-d3. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Prochlorperazine Dimesylate
Antiemetic, antipsychotic; used in treatment of vertigo. Group: Biochemicals. Alternative Names: 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine Dimethanesulfonate; 3-Chloro-10-[3- (4-methyl-1-piperazinyl) propyl]phenothiazine Dimesylate; Novamin; Tementil. Grades: Highly Purified. CAS No. 51888-09-6. Pack Sizes: 5mg. US Biological Life Sciences.
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(R,cis)-7-Methyl Atracurium dibesylate
(R,cis)-7-Methyl Atracurium dibesylate is an impurity of Cisatracurium, an enantiomer of a neuromuscular blocking agent. Synonyms: (1R,2R,1'R,2'R)-2,2'-{(3-Methyl-1,5-pentanediyl)bis[oxy(3-oxo-3,1-propanediyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium] dimethanesulfonate; (1R,1'R,2R,2'R)-2,2'-(((3-Methylpentane-1,5-diyl)bis(oxy))bis(3-oxopropane-3,1-diyl))bis(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium)Dibesylate. CAS No. 1193104-80-1. Molecular formula: C56H80N2O18S2. Mole weight: 1133.37.
Treosulfan is the prodrug of a bifunctional sulfonate alkylating agent with myeloablative, immunosuppresive, and antineoplastic activities. Under physiological conditions, treosulfan converts nonenzymatically to L-diepoxybutane via a monoepoxide intermediate. The monoepoxide intermediate and L-diepoxybutane alkylate DNA at guanine residues and produce DNA interstrand crosslinks, resulting in DNA fragmentation and apoptosis. In escalated doses, this agent also exhbits myeloablative and immunosuppressive activities. Synonyms: NSC 39069; NSC39069; NSC-39069; Treosulfan; (2S,3S)-2,3-Dihydroxybutane-1,4-diyl dimethanesulfonate. CAS No. 299-75-2. Molecular formula: C6H14O8S2. Mole weight: 278.29.
TRX-0237 mesylate
TRX-0237 mesylate is a second-generation tau protein aggregation inhibitor applicated for the treatment of AD (Alzheimer's disease) and frontotemporal dementia. TRX-0237 is the purified form of Methylene Blue, an old drug that has being widely used in Africa for the treatment of malaria, methemoglobinemia and other conditions for a long time. TRX-0237 is the stabilized, reduced form of methylthioninium chloride to improve the drug's absorption, bioavailability, and tolerability. TRX-0237 is in Phase I for Parkinson's disease, Phase II for Progressive supranuclear palsy and Phase III for Alzheimer's disease and Dementia. Uses: Parkinson's disease; progressive supranuclear palsy; alzheimer's disease; dementia. Synonyms: TRX-0237 mesylate; TRX 0237 mesylate; TRX0237 mesylate; Leucomethylene blue (Mesylate); AKOS026750731; CS-5553; AK-499443; HY-19948; CS 5553; AK 499443; HY 19948; CS5553; AK499443; HY19948; N3,N3,N7,N7-Tetramethyl-10H-phenothiazine-3,7-diamine dimethanesulfonate. Grades: 98%. CAS No. 1236208-20-0. Molecular formula: C18H27N3O6S3. Mole weight: 477.6.