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Dimethindene is a selective histamine H1 antagonist. It binds to the histamine H1 receptor. It is an antiallergic drug and is used in hypersensitivity reactions, in rhinitis, for pruritus, and in some common cold remedies. It is an antihistamine/anticholinergic used orally and locally as an antipruritic. It blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine. It has been listed. Uses: Dimethindene is an antiallergic drug and is used in hypersensitivity reactions, in rhinitis, for pruritus, and in some common cold remedies. it is an antihistamine/anticholinergic used orally and locally as an antipruritic. Synonyms: Z 2001; Z2001; Z-2001; Dimethindene; Dimetindene; Dimetindeno; 2-(1-(2-(2-Dimethylaminoethyl)inden-3-yl)ethyl)pyridine; Dimethpyrindene; Forhistal; N, N-Dimethyl-2-(3-[1-(2-pyridinyl)ethyl]-1H-inden-2-yl)ethanamine; Pyridine, 2-(1-(2-(2-(dimethylamino)ethyl)inden-3-yl)ethyl)-. Grades: 98%. CAS No. 5636-83-9. Molecular formula: C20H24N2. Mole weight: 292.42.
Dimethindene-d6 Maleate
Dimethindene-d6 Maleate is labelled Dimethindene Maleate (D460460) which is a salt of Dimethindene, an antihistamine / anticholinergic used orally and locally as an antipruritic. Dimethindene is an H1-antagonist of high potency. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C24H22D6N2O4, Molecular Weight: 414.53. US Biological Life Sciences.
Worldwide
Dimethindene Impurity H (2-[(1RS)-1-(2-ethenyl-1H-Inden-3-yl)ethyl]pyridine)
Dimethindene impurity and a histaminic H1 receptor antagonist. Synonyms: 3-[1-(2-Pyridinyl)ethyl]-2-vinyl-1H-indene; 2-De(dimethylamino)-2-vinyl Dimethindene. Grades: > 95%. CAS No. 1346597-95-2. Molecular formula: C18H17N. Mole weight: 247.33.
Dimethindene maleate
Dimethindene maleate is a selective histamine H1 antagonist with antihistamine effects. Dimethindene maleate can be used for the research of hypersensitivity reactions [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3614-69-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13710A.
Dimethindene Maleate
Dimethindene Maleate is a salt of Dimethindene which is an antihistamine / anticholinergic used orally and locally as an antipruritic. Dimethindene is an H1-antagonist of high potency. Group: Biochemicals. Grades: Highly Purified. CAS No. 3614-69-5. Pack Sizes: 1mg, 10mg. Molecular Formula: C24H28N2O4, Molecular Weight: 408.49. US Biological Life Sciences.
Worldwide
(S)-(+)-Dimethindene maleate
(S)-(+)-Dimethindene maleate, an enantiomer, is a potent M 2 -selective muscarinic receptor antagonist ( pA 2 = 7.86/7.74; pK i = 7.78). (S)-(+)-Dimethindene maleate shows lower affinities for the muscarinic M 1 (pA 2 = 6.83/6.36; pK i = 7.08), the M 3 (pA 2 = 6.92/6.96; pK i = 6.70) and the M 4 receptors (pK i = 7.00), respectively. (S)-(+)-Dimethindene maleate also is a histamine H 1 receptor antagonist ( pA 2 = 7.48) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 136152-65-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107647.
(S)-(+)-Dimethindene maleate
(S)-(+)-Dimethindene maleate. Group: Biochemicals. Grades: Purified. CAS No. 136152-65-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
(S)-(+)-Dimethindene Maleate
The maleate salt form of (S)-(+)-Dimethindene, which has been found to be a subtype-selective mAChR M2 antagonist and histamine H1 receptor antagonist. Synonyms: 1H-Indene-2-ethanamine, N,N-dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-, (2Z)-2-butenedioate (1:1); 1H-Indene-2-ethanamine, N,N-dimethyl-3-[1-(2-pyridinyl)ethyl]-, (+)-, (Z)-2-butenedioate (1:1); N,N-Dimethyl-3-[(1S)-1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine maleate; (+)-Dimethindene maleate; (S)-Dimethindene maleate; (S)-N,N-dimethyl-2-(3-(1-(pyridin-2-yl)ethyl)-1H-inden-2-yl)ethan-1-amine maleate. Grades: ≥99% by HPLC. CAS No. 136152-65-3. Molecular formula: C20H24N2.C4H4O4. Mole weight: 408.50.
Dimetindene maleate
Dimethindene is a histamine H1 antagonist of high potency used orally and locally as an antipruritic. Uses: Antipruritic. Synonyms: Fenistil-retard; Forhistal maleate; U 6518; SU-6518; UNII-6LL60J9E0O; Dimethindene maleate; Dimethpyrindene maleate;Dimetindene maleate; EINECS 222-789-2; Fenistil; Fenistil-retard; Forhistal maleate; NSC 107677; N,N-Dimethyl-3-[1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine maleate; (Z)-but-2-enedioic acid; N,N-dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethanamine. Grades: ≥98%. CAS No. 3614-69-5. Molecular formula: C24H28N2O4. Mole weight: 408.498.
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