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| Product | Description | |
|---|---|---|
| Diminazene aceturate | Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Diminazene diaceturate. CAS No. 908-54-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-12404. |  |
| Diminazene Aceturate | Diminazene aceturate is an ACE activator, inhibiting MAPKs and STAT phosphorylation. Diminazene aceturate is an anti-trypanosome agent for livestock. Synonyms: 1,3-Bis[4-guanylphenyl]triazene diaceturate; 4,4'-(Diazoamino)dibenzamidine Diaceturate; 4,4'-Diamidinodiazoaminobenzene Diaceturate. Grades: >98%. CAS No. 908-54-3. Molecular formula: C22H29N9O6. Mole weight: 515.52. |  |
| Bruceine A | Bruceine A(NSC310616; Dihydrobrusatol) is a natural quassinoid compound extracted from the dried fruits of Brucea javanica (L.); are potential candidates for the treatment of canine babesiosis.IC50 value:Target:Bruceine A inhibited the in vitro growth of Babesia gibsoni in canine erythrocytes at lower concentration compared with the standard antibabesial drug diminazene aceturate and killed the parasites within 24 hr at a concentration of 25 nM. Oral administration of bruceine A at a dosage of 6.4 mg/kg/day for 5 days resulted in no clinical findings in a dog with normal ranges of hematological and biochemical values in the blood. Three dogs were infected with B. gibsoni and two of them were treated with bruceine A at a dosage of 6.4 mg/kg/day for 6 days from day 5 post-infection. Group: Inhibitors. CAS No. 25514-31-2. Molecular formula: C26H34O11. Mole weight: 522.54. Appearance: Powder. Purity: 0.98. Canonical SMILES: CC1=C (C (=O)CC2 (C1CC3C45C2C (C (C (C4C (C (=O)O3)OC (=O)CC (C)C) (OC5)C (=O)OC)O)O)C)O. Catalog: ACM25514312. |  |
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