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| Product | Description | |
|---|---|---|
| Dipraglurant | Dipraglurant (ADX48621) is a potent, selective, orally active and brain penetrant mGluR5 negative allosteric modulator (NAM), with an IC 50 of 21 nM. Dipraglurant can reduce Levodopa-induced dyskinesia (LID) in vivo [1] [2]. Dipraglurant is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ADX48621. CAS No. 872363-17-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-14859. |  |
| Dipraglurant | Dipraglurant is a mGlu5 receptor negative allosteric modulator. It is currently in phase II for the treatment of dyskinesia in Parkinson's disease. Synonyms: ADX-48621; ADX48621; ADX 48621; Dipraglurant. Grades: >98%. CAS No. 872363-17-2. Molecular formula: C16H12FN3. Mole weight: 265.29. |  |
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