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| Product | Description | |
|---|---|---|
| Diroximel fumarate | Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF). Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS). Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ALKS 8700; BIIB098. CAS No. 1577222-14-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100375. |  |
| Diroximel Fumarate | Diroximel Fumarate is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body. It reduces the progressive damage to nerve cells via activating the Nrf2 pathway. It also acts as a NF-kappa B inhibitor. Synonyms: ALKS8700; ALKS 8700; ALKS-8700; 2-(2,5-Dioxopyrrolidin-1-yl)ethyl methyl fumarate; 4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate. Grades: 98%. CAS No. 1577222-14-0. Molecular formula: C11H13NO6. Mole weight: 255.226. |  |
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