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| Product | Description | |
|---|---|---|
| DL-TBOA | DL-TBOA is a competitive and non-transportable inhibitor of excitatory amino acid transporters (IC50 = 70, 6, and 6 μM for EAAT1, EAAT2 and EAAT3, respectively). DL-TBOA also inhibits EAAT4 and EAAT5 (Ki = 4.4 and 3.2 μM, respectively). DL-TBOA is a glutamate uptake inhibitor. Synonyms: DL-threo-β-Benzyloxyaspartic acid; (2S,3S)-2-amino-3-phenylmethoxybutanedioic acid. Grade: ≥98% by HPLC. CAS No. 205309-81-5. Molecular formula: C11H13NO5. Mole weight: 239.23. |  |
| DL-TBOA | DL-TBOA is a potent non-transportable inhibitor of excitatory amino acid transporters with IC50s of 70 ?M, 6 ?M and 6 ?M for excitatory amino acid transporter-1 (EAAT1), EAAT2 and EAAT3, respectively. DL-TBOA inhibits the uptake of [14C]glutamate in COS-1 cells expressing the human EAAT1 and EAAT2 with Ki valuesof 42 ?M and 5.7 ?M, respectively. DL-TBOA blocks EAAT4 and EAAT5 in a competitive manner with Ki values of 4.4 ?M and 3.2 ?M, respectively[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 205309-81-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-107522. |  |
| DL-TBOA ammonium | DL-TBOA ammonium is a potent non-transportable EAATs inhibitor with IC50s of 70, 6 and 6 μM for excitatory amino acid transporter-1 (EAAT1), EAAT2 and EAAT3, respectively. It competitively blocks EAAT4 and EAAT5 with Kis of 4.4 and 3.2 μM, respectively. It inhibits the uptake of [14C]glutamate in COS-1 cells expressing the human EAAT1 and EAAT2 with Kis of 42 and 5.7 μM, respectively. Synonyms: DL-threo-beta-benzyloxyaspartate ammonium salt; (3S)-3-(Phenylmethoxy)-L-aspartic acid aammonium salt; (2S,3S)-2-amino-3-(benzyloxy)succinic acid, ammonium salt; (3S)-3-(Benzyloxy)-L-aspartic acid ammoniate (1:1); D-Aspartic acid, 3-(phenylmethoxy)-, ammonium salt (1:1), (3R)-rel-. Grade: ≥95%. CAS No. 2093503-71-8. Molecular formula: C11H16N2O5. Mole weight: 256.26. | |
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