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| Product | Description | |
|---|---|---|
| Dofequidar | Dofequidar, also known as MS-209, is a quinolone-derived sphingomyelin synthase inhibitor that blocks P-glycoprotein and multidrug resistance-associated protein-1, is under development by Schering for the potential treatment of multidrug resistant tumors. Dofequidar was found to sensitizes cancer stem-like side population cells to chemotherapeutic drugs by inhibiting ABCG2/BCRP-mediated drug export. Uses: Antineoplastic agents. Synonyms: Dofequidar. CAS No. 129716-58-1. Molecular formula: C30H31N3O3. Mole weight: 481.596. |  |
| Dofequidar fumarate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Dofequidar fumarate | Dofequidar fumarate, a quinoline derivative, is a multidrug resistance (MDR)-reversing quinoline derivative by inhibiting ABCB1/P-gp, ABCC1/MDR-associated protein 1, or both. It has potential to treat advanced and recurrent breast cancer and non-small lun. Synonyms: MS-209; MS 209; MS209. CAS No. 153653-30-6. Molecular formula: C34H35N3O7. Mole weight: 597.66. | |
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