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| Product | Description | |
|---|---|---|
| Dolutegravir Impurity 25 | Dolutegravir Impurity 25. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4R,12aS)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxylic acid. CAS No. 1246616-73-8. Molecular formula: C13H14N2O6. Mole weight: 294.09. Catalog: APB1246616738. |  |
| Dolutegravir Impurity 7 | Dolutegravir Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4R,12aS)-N-(4-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide. CAS No. 1863916-88-4. Molecular formula: C20H20FN3O5. Mole weight: 401.39. Catalog: APB1863916884. | |
| Dolutegravir Impurity 8 | Dolutegravir Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide. CAS No. 1863916-87-3. Molecular formula: C20H20FN3O5. Mole weight: 401.39. Catalog: APB1863916873. | |
| Dolutegravir Impurity B | An impurity of Dolutegravir. Dolutegravir is an antiretroviral drug belonging to the integrase strand transfer inhibitor (INSTI) class. Synonyms: N-[(2,4-Difluorophenyl)methyl]-1,8-dihydro-9-hydroxy-2-(3-hydroxy-1-methylpropyl)-1,8-dioxo-2H-pyrido[1,2-a]pyrazine-7-carboxamide; Dolutegravir ring open impurity; N-(2,4-Difluorobenzyl)-9-hydroxy-2-(4-hydroxybutan-2-yl)-1,8-dioxo-1,8-dihydro-2H-pyrido[1,2-a]pyrazine-7-carboxamide. Grade: ≥95%. CAS No. 2374716-73-9. Molecular formula: C20H19F2N3O5. Mole weight: 419.38. |  |
| 1-(2,2-Dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester | 1-(2,2-Dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester is an intermediate used in the synthesis of Defluoro Dolutegravir (D228715), which is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Group: Biochemicals. Grades: Highly Purified. CAS No. 1246616-75-0. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H21NO7, Molecular Weight: 327.33. US Biological Life Sciences. |  Worldwide |
| 2-Defluoro Dolutegravir | An impurity of Dolutegravir. Dolutegravir is an antiretroviral drug belonging to the integrase strand transfer inhibitor (INSTI) class. Synonyms: (4R,12aS)-N-[(4-Fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; Defluoro dolutegravir; Dolutegravir Impurity G; 4-Flurobenzyl Imp of Dolutegravir; 4-Fluoro dolutegravir; Dolutegravir 2-desfluoro impurity. Grade: ≥95%. CAS No. 1863916-88-4. Molecular formula: C20H20FN3O5. Mole weight: 401.39. | |
| 3-Bromo-1-(2,2-dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester | 3-Bromo-1-(2,2-dimethoxyethyl)-1,4-dihydro-4-oxo-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester is an intermediate in the synthesis of Defluoro Dolutegravir (D228715). Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Group: Biochemicals. Grades: Highly Purified. CAS No. 1246616-76-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C15H20BrNO7, Molecular Weight: 406.23. US Biological Life Sciences. | Worldwide |
| 3-Bromo-1,4-dihydro-4-oxo-1-(2-oxoethyl)-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester | 3-Bromo-1,4-dihydro-4-oxo-1-(2-oxoethyl)-2,5-pyridinedicarboxylic Acid 2,5-Diethyl Ester is an intermediate in the synthesis of Defluoro Dolutegravir (D228715). Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector. Group: Biochemicals. Grades: Highly Purified. CAS No. 1246616-77-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C13H14BrNO6, Molecular Weight: 360.16. US Biological Life Sciences. | Worldwide |
| 4-Defluoro Dolutegravir | An impurity of Dolutegravir. Dolutegravir is an antiretroviral drug belonging to the integrase strand transfer inhibitor (INSTI) class. Synonyms: Dolutegravir Impurity C; 2-Flurobenzyl Imp of Dolutegravir; 2-Fluoro Dolutegravir; (4R,12aS)-N-[(2-Fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; Dolutegravir 4-desfluoro impurity; (4R,12aS)-N-(2-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide. Grade: ≥95%. CAS No. 1863916-87-3. Molecular formula: C20H20FN3O5. Mole weight: 401.39. | |
| 4-Desfluoro-6-fluoro Dolutegravir | An impurity of Dolutegravir. Dolutegravir is an antiretroviral drug belonging to the integrase strand transfer inhibitor (INSTI) class. Synonyms: 2,6-Difluoro Dolutegravir; 2,6-Flurobenzyl Dolutegravir; (4R,12aS)-N-(2,6-Difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; (4R,12aS)-N-[(2,6-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide; Dolutegravir 2,6-Difluoro Analog; Dolutegravir 4-Desfluoro 6-Fluoro Impurity. Grade: ≥95%. CAS No. 2244161-72-4. Molecular formula: C20H19F2N3O5. Mole weight: 419.38. | |
| Dolutegravir (Sodium Salt) | Dolutegravir (Sodium Salt). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (4R,12aS)-9-((2,4-difluorobenzyl)carbamoyl)-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazin-7-olate. CAS No. 1051375-19-9. Molecular formula: C20H18F2N3O5·Na. Mole weight: 443.38. Catalog: APB1051375199. | |
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