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Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body [1]. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptor s to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis [1]. Uses: Scientific research. Group: Natural products. Alternative Names: ASL279. CAS No. 62-31-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0451A.
Dopamine Hydrochloride
Endogenous catecholamine with α and β-adrenergic activity. Cardiotonic; antihypotensive. Group: Biochemicals. Alternative Names: 4-(2-Aminoethyl)-1,2-benzenediol Hydrochloride; 4- (2-Aminoethyl) pyrocatechol Hydrochloride. Grades: Highly Purified. CAS No. 62-31-7. Pack Sizes: 1g. US Biological Life Sciences.
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6-Hydroxy Dopamine Hydrochloride
6-Hydroxydopamine is a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson's disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells. Group: Biochemicals. Alternative Names: 2, 4, 5-Trihydroxyphene thylamine Hydrochloride; 5-(2-Aminoethyl)-1,2,4-benzenetriol Hydrochloride; 6-Hydroxydopamine Hydrochloride; Oxidopamine Hydrochloride; Topamine Hydrochloride. Grades: Highly Purified. CAS No. 28094-15-7. Pack Sizes: 2.5mg. US Biological Life Sciences.
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Bupropion Hydrochloride (Dopamine and Noradrenalin Transporter Inibitor, Bupropion)
A non-selective inhibitor of dopamine and noradrenalin transporters (Ki = 1.4, 2.8 and 45uM for dopamine, noradrenalin, and serotonin transporters respectively). Also an antagonist for neuronal nicotinic acetylcholine receptors (nAChrs) (IC50 = 1.8uM at alpha2beta2 receptor). Clinically used as an antidepressant and smoking cessation drug. Used in nicotinic addiction and depression studies. Group: Biochemicals. Grades: Highly Purified. CAS No. 31677-93-7. Pack Sizes: 50mg. Molecular Formula: C??H??ClNO·HCl. US Biological Life Sciences.
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Dopamine-d3 hydrochloride
Dopamine-d 3 (hydrochloride) is the deuterium labeled Dopamine hydrochloride (ASL279)-[1]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: ASL279-d3. CAS No. 53587-30-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0451AS4.
Dopamine-d5 hydrochloride
Dopamine-d 5 (hydrochloride) is the deuterium labeled Dopamine (hydrochloride). Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body[1]. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 2193106-55-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-B0451AS7.
A neurotoxin that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism. Widely used in research to induce Parkinson's disease models in primates. Group: Biochemicals. Grades: Highly Purified. CAS No. 23007-85-4. Pack Sizes: 10mg. Molecular Formula: C??H??N·HCl. US Biological Life Sciences.
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Oxidopamine hydrochloride
Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride is a widely used neurotoxin and selectively destroys dopaminergic neurons. Oxidopamine hydrochloride promotes COX-2 activation, leading to PGE 2 synthesis and pro-inflammatory cytokine IL-1β secretion. Oxidopamine hydrochloride can be used for the research of Parkinsons disease (PD), attention-deficit hyperactivity disorder (ADHD), and Lesch-Nyhan syndrome [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 6-Hydroxydopamine Hydrochloride. CAS No. 28094-15-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1081.
Oxidopamine hydrochloride
Oxidopamine hydrochloride, also called as 6-OHDA, is a selective catecholaminergic neurotoxin that selectively destroy dopaminergic and noradrenergic neurons in the brain. Synonyms: 5-(2-aminoethyl)benzene-1,2,4-triol;hydrochloride 6 Hydroxydopamine 6-Hydroxydopamine 6-OHDA Hydrobromide, Oxidopamine Hydrochloride, Oxidopamine Oxidopamine Oxidopamine Hydrobromide Oxidopamine Hydrochloride. CAS No. 28094-15-7. Molecular formula: C8H12ClNO3. Mole weight: 205.64.
Selective dopamine D3 receptor agonist (Ki = 2.3nM) with an 18-fold selectivity over long dopamine receptors (D2L) and exhibited only weak affinity for D4.2 receptors (Ki = 169nM). Commonly used to reproduce cocaine's discriminative stimulus effects and also in peripheral systemic studies of hypertension. Group: Biochemicals. Grades: Highly Purified. CAS No. 112960-16-4. Pack Sizes: 5mg. Molecular Formula: C??H??NO? HCl. US Biological Life Sciences.
A potent, selective dopamine D2 receptor agonist with a Ki value of 4.8nM. Some D3(Ki = 24nM) and D4 (Ki = 30nM) receptor agonistic action has also been reported. In rat striatum studies in vitro, application of quinpriole inhibited single pulse dopamine overflow in a concentration-dependent manner (IC50 = 32.5nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 85798-08-9. Pack Sizes: 10mg. US Biological Life Sciences.
A highly potent non-ergoline dopamine D2 and D3 receptor agonist (Ki = 13 and 0.71nM for D2 and D3 respectively). Also displays significant affinity for 5-HT1A and adrenergic alpha2B receptors. Transdermally used in treatment of Parkinson's disease and restless legs syndrome. Group: Biochemicals. Grades: Highly Purified. CAS No. 125572-93-2. Pack Sizes: 10mg. Molecular Formula: C??H??NOS HCl. US Biological Life Sciences.
A benzazepine derivative that acts as a selective Dopamine D1/D5 receptor partial agonist. Examination of the isomers in several in vitro and in vivo tests for both central and peripheral dopaminergic activity revealed that activity resided almost exclusively in the R isomer. The results suggest that the properly oriented 1-phenyl substituent of 1 is important for dopamine-like activity. Reported to have stimulant and anorectic effects. Group: Biochemicals. Grades: Highly Purified. CAS No. 81702-42-3. Pack Sizes: 5mg. Molecular Formula: C16H??NO? HCl. US Biological Life Sciences.
A highly potent and selective dopamine D1-like receptor antagonist with a Ki of 0.2 and 0.3nM for the D1 and D5 dopamine receptor subtypes, respectively. Also an agonist at 5-HT1C and 5-HT2C receptors in vitro (Ki values are 6.3nM and 9.3nM respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 125941-87-9. Pack Sizes: 10mg. Molecular Formula: C??H??ClNO HCl. US Biological Life Sciences.
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(S)-Duloxetine Hydrochloride (Potent 5-HT and NA Reuptake Inhibitor, Blocks Dopamine Reuptake, (+)-(S)-N-Methyl-3-(1-naphthyloxy)- 3-(2-thienyl)propanamine hydrochloride)
High affinity, competitive 5-HT and norepinephrine (NE) re-uptake inhibitor (Ki values are 8.5 and 45nm for 5-HT and NE reuptake respectively in cortical synaptosomes; IC50 values are 28 and 46nm for 5-HT and NE reuptake respectively in rat hippocampal slices). Also blocks dopamine reuptake (Ki=300nm in striatal synaptosomes). Exhibits antidepressant and anxiolytic effects. Orally bioavailable. Group: Biochemicals. Grades: Highly Purified. CAS No. 136434-34-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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1-Methyl-4-imidazoleacetic Acid Hydrochloride
1-Methyl-4-imidazoleacetic Acid Hydrochloride is a metabolite of histamine (H436500), which is produced by mast cells and involved with the inflammatory response. 1-Methyl-4-imidazoleacetic Acid Hydrochloride can also be used to synthesize N- [1- (9, 10-methano-9-anthracenylmethyl) -4-piperidinyl] alkanamides and analogs as dopamine D2 receptor antagonists. Group: Biochemicals. Grades: Highly Purified. CAS No. 35454-39-8. Pack Sizes: 10mg, 50mg. Molecular Formula: C6H9ClN2O2, Molecular Weight: 176.6. US Biological Life Sciences.
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1-Morpholinocyclopentene
1-Morpholinocyclopentene is used as a reagent to synthesize cis- and trans-2- (3, 4-dimethoxybenzyl) cyclopentylamine hydrochlorides, compounds that display antagonistic effects against dopamine-induced vasodepression. Group: Biochemicals. Grades: Highly Purified. CAS No. 936-52-7. Pack Sizes: 2.5g, 10g. Molecular Formula: C9H15NO, Molecular Weight: 153.22. US Biological Life Sciences.
(1R,2S)-erythro-Dihydro Bupropion-d9 Hydrochloride is labelled (1R,2S)-erythro-Dihydro Bupropion Hydrochloride which is a metabolite of Bupropion, a selective inhibitor of dopamine uptake. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C13H12D9Cl2NO, Molecular Weight: 287.27. US Biological Life Sciences.
(1R-trans)- 1,2,3,4-Tetrahydro-7-methoxy-2-(propylamino)-1-naphthalenol is an intermediate in the synthesis of Naxagolide Hydrochloride (N379800), which is a dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 111056-74-7. Pack Sizes: 25mg, 50mg. Molecular Formula: C14H21NO2. US Biological Life Sciences.
(1R-trans)-2-Chloro-N-propyl-N-(1,2,3,4-tetrahydro-1-hydroxy-7-methoxy-2-naphthalenyl)-acetamide is an intermediate in the synthesis of Naxagolide Hydrochloride (N379800), which is a dopamine D2-receptor agonist. Used for treatment of extrapyramidal disorders. Antiparkinsonian drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 110936-07-7. Pack Sizes: 10mg, 25mg. Molecular Formula: C16H22ClNO3, Molecular Weight: 311.8. US Biological Life Sciences.
(1S,2R)-erythro-Dihydro Bupropion-d9 Hydrochloride is labelled (1S,2R)-erythro-Dihydro Bupropion Hydrochloride (D448295) which is a metabolite of Bupropion (B689625), a selective inhibitor of dopamine uptake. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 10mg. Molecular Formula: C13H12D9Cl2NO, Molecular Weight: 287.27. US Biological Life Sciences.
2,10-Dimethoxy-6-propyl-6a β-noraporphin-11-ol Hydrochloride is an intermediate in the synthesis of R(-)-2-Hydroxy-N-propylnorapomorphine Hydrobromide Salt (R701253), which is a potent and selective D2 dopamine receptor agonist (2). The dopamine receptors play important role in cognition, memory, learning, and motor control (1). These receptors have been implicated as a therapeutic target for many psychiatric and neurological disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 126874-87-1. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C21H25NO3; (HCl), Molecular Weight: 339.433646. US Biological Life Sciences.
2-[ (1-Methyl-2-phenylethyl) amino]acetonitrile Hydrochloride is an intermediate in the synthesis of metabolite of Mesocarb (M225650), a CNS stimulant that acts as a dopamine reuptake inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 30825-15-1. Pack Sizes: 10mg, 25mg. Molecular Formula: C11H15ClN2. US Biological Life Sciences.
2-(2-(2-(Methylthio)-10H-phenothiazin-10-yl)ethyl)piperidine-1-carbaldehyde is a metabolite of the extensively biotransformed piperidine type phenothiazine antipsychotic agent and dopamine receptor blocker, thioridazine hydrochloride (T368800). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 100mg. Molecular Formula: C21H24N2OS2. US Biological Life Sciences.
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2- (2-Chloroethyl) -1-piperidinecarboxalde hyde
2- (2-Chloroethyl) -1-piperidinecarboxalde hyde is an constituent in the synthesis of phenothiazine antipsychotic agent and dopamine receptor blocker, thioridazine hydrochloride (T368800). Group: Biochemicals. Grades: Highly Purified. CAS No. 128183-77-7. Pack Sizes: 50mg, 250mg. Molecular Formula: C8H14ClNO. US Biological Life Sciences.
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2- (2- hydroxyethyl) -1-piperidinecarboxalde hyde
2- (2- hydroxyethyl) -1-piperidinecarboxalde hyde is an constituent in the synthesis of phenothiazine antipsychotic agent and dopamine receptor blocker, thioridazine hydrochloride (T368800). Group: Biochemicals. Grades: Highly Purified. CAS No. 84681-79-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C8H15NO2. US Biological Life Sciences.
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2-(3,4-Dihydroxyphenyl)ethyl-1-13C-amine-15N HCl
2-(3,4-Dihydroxyphenyl)ethyl-1-13C-amine-15N HCl. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Dopamine HCl; 3-Hydroxytyramine HCl; 3,4-Dihydroxyphenethylamine HCl. Product Category: Heterocyclic Organic Compound. CAS No. 369656-74-6. Molecular formula: (HO)2C6H3CH213CH215NH2·HCl. Mole weight: 191.66. Purity: 99 atom % 13C 99 atom % 15N. IUPACName: 4-(2-azanylethyl)benzene-1,2-diol;hydrochloride. Canonical SMILES: C1=CC(=C(C=C1CCN)O)O.Cl. Product ID: ACM369656746. Alfa Chemistry ISO 9001:2015 Certified.
3-(2-Chloroethyl)-9-hydroxy-2-methyl-4H-Pyrido[1,2-a]pyrimidin-4-one Hydrochloride is an intermediate in the synthesis of analog of Paliperidone (P141000), a combined serotonin and dopamine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 849727-62-4. Pack Sizes: 25mg, 250mg. Molecular Formula: C11H12Cl2N2O2. US Biological Life Sciences.
3-(3,4-Dimethylphenyl)-1-propyl-piperidine Hydrochloride is a highly selective ligand for the D4 dopamine receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 219704-16-2. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H25N HCl, Molecular Weight: 231.383646. US Biological Life Sciences.
3,4-Dihydroxyphenylethylamine-8-14c hydrochloride-8-14c. Uses: Designed for use in research and industrial production. Additional or Alternative Names: DOPAMINE-8-14C HYDROCHLORIDE;3,4-DIHYDROXYPHENYLETHYLAMINE-8-14C HYDROCHLORIDE-8-14C;3-HYDROXYTYRAMINE-8-14C HYDROCHLORIDE-8-14C;3,4-Dihydroxyphenylethylamine, 3-Hydroxytyramine. Product Category: Heterocyclic Organic Compound. CAS No. 60109-35-5. Molecular formula: C8H12ClNO2. Mole weight: 191.66. Product ID: ACM60109355. Alfa Chemistry ISO 9001:2015 Certified.
A potent inhibitor of dopamine uptake and transport (Ki = 11.8 nM). Synonyms: 3-[bis(4-fluorophenyl)methoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride. CAS No. 202646-03-5. Molecular formula: C21H23F2NO.HCl. Mole weight: 379.88.
3-CPMT
3-CPMT, a cocaine analogue, is a dopamine transporter blocker and has been found to be a weak psychomotor stimulant. Synonyms: 3-CPMT; 3 CPMT; 3CPMT; 3α-[(4-Chlorophenyl)phenylmethoxy] tropane hydrochloride. Grades: ≥99% by HPLC. CAS No. 14008-79-8. Molecular formula: C21H24ClNO.HCl. Mole weight: 378.34.
3-Deschloro-2-chloro Bupropion Hydrochloride
An positional isomeric impurity of the selective dopamine uptake inhibior Bupropion. Group: Biochemicals. Alternative Names: 1-(2-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone Hydrochloride; 2-(tert-Butylamino)-2-chloropropiophenone Hydrochloride. Grades: Highly Purified. CAS No. 1049718-57-1. Pack Sizes: 25mg. US Biological Life Sciences.
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3-Methoxy-p-tyramine Hydrochloride
3-Methoxy-p-tyramine is a major metabolite of Dopamine. Synonyms: 4-(2-Aminoethyl)-2-methoxyphenol Hydrochloride; 4-(2-Aminoethyl)guaiacol Hydrochloride; 2-Methoxytyramine Hydrochloride; 3-Methoxy-4-hydroxy-phenethylamine Hydrochloride; 3-O-Methyldopamine Hydrochloride; 4-(2-Aminoethyl)-2-methoxyphenol Hydrochloride; 4-. Grades: > 95%. CAS No. 1477-68-5. Molecular formula: C9H14ClNO2. Mole weight: 203.67.
3-Methoxytyramine-d4 hydrochloride
3-Methoxytyramine-d 4 (hydrochloride) is the deuterium labeled 3-Methoxytyramine hydrochloride. 3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1)[1][2]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: 3-O-methyl Dopamine-d4 hydrochloride. CAS No. 1216788-76-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-103638S.
3-Methoxytyramine hydrochloride
3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 ( TAAR1 ). Uses: Scientific research. Group: Natural products. Alternative Names: 3-O-methyl Dopamine hydrochloride. CAS No. 1477-68-5. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-103638.
3-Oxo Ropinirole HCl (Ropinirole Related Compound B)
An impurity of Ropinirole.Ropinirole acts as a D2, D3, and D4 dopamine receptor agonist with highest affinity for D2. It is weakly active at the 5-HT2, and α2 receptors and is said to have virtually no affinity for the 5-HT1, GABA, mAChRs, α1, and β-adrenoreceptors. Synonyms: 4-[2-(Dipropylamino)ethyl]-1H-indole-2,3-dione Hydrochloride; 4-[2-(Dipropylamino)ethyl]isatin Hydrochloride; SKF 96266 Hydrochloride; Ropinirole Impurity C, Impurity III, Ropinirole Related Compound B. Grades: > 95%. CAS No. 221264-21-7. Molecular formula: C16H22N2O2. Mole weight: 310.83.
The active metabolite of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) , N-Methyl-4-phenylpyridinium (MPP+), selectively destroys the dopaminergic neurons and induces the symptoms of Parkinson's disease. Group: Biochemicals. Alternative Names: 4-(4-Fluorophenyl)-1,2,3,6-tetrahydro-1-methylpyridine Hydrochloride. Grades: Highly Purified. CAS No. 1012886-75-7. Pack Sizes: 25mg. US Biological Life Sciences.
4,9-Diacetyl (+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol is a derivative of (+)-3,4,4a,5,6,10b-Hexahydro-2H-naphtho[1,2-b][1,4]oxazin-9-ol Hydrochloride (H294075), a dopamine agonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Sigma-LIGAND-1, also called as NPC 16377, is a selective sigma receptor ligand developed for the treatment of neurological disorders and psychotic disorders in the past. NPC 16377 has receptor IC50s of 16 nM at the DTG site, 19 nM at the PPP site, and a Ki of 4000 nM at the dopamine D2 receptor. Synonyms: 6-[6-(4-hydroxypiperidin-1-yl)hexoxy]-3-methyl-2-phenylchromen-4-one; 6-(6-(4-hydroxypiperidinyl)hexyloxy)-3-methylflavone hydrochloride; NPC 16377; NPC-16377; NPC16377. CAS No. 139652-01-0. Molecular formula: C27H33NO4. Mole weight: 435.56.
4-Methoxy Tryamine HCl
4-Methoxy Tryamine HCl is a derivative of Dopamine with α and β-adrenergic activity. 4-Methoxy Tryamine HCl is commonly used as cardiotonic and antihypotensive. Synonyms: 3-Hydroxy-4-methoxyphenethylamine Hydrochloride; 4-O-Methyldopamine Hydrochloride; 5-(2-Aminoethylguaiacol Hydrochloride; 5-(2-Aminoethyl)-2-methoxyphenol Hydrochloride; 2-(3-Hydroxy-4-methoxyphenyl)ethanamine Hydrochloride 3-Hydroxy-4-methoxy-β-phenethylamine Hydrochloride 3-Hydroxy-4-methoxyphenethylamine Hydrochloride. CAS No. 645-33-0. Molecular formula: C9H13NO2.HCl. Mole weight: 207.63.
5,6-Dihydroxy-N-methyl-N-propyl-Aminotetraline hydrochloride is a dopamine receptor agonist. Synonyms: Aminotetraline hydrochloride, 5,6-Dihydroxy-N-methyl-N-propyl-; 6-[methyl(propyl)amino]-5,6,7,8-tetrahydronaphthalene-1,2-diol;hydrochloride. Grades: 98%. CAS No. 55218-13-8. Molecular formula: C14H21NO2.HCl. Mole weight: 271.78.
5-Iodo-A-85380 dihydrochloride
5-Iodo-A-85380 dihydrochloride is the dihydrochloride salt of 5-Iodo-A-85380, which is a highly potent and subtype-selective agonist for α4β2 and α6β2 nicotinic acetylcholine receptors. It activates α-CTx-MII-sensitive and -insensitive components of [3H]dopamine release from rat striatal synaptosomes. Synonyms: Pyridine, 3-[(2S)-2-azetidinylmethoxy]-5-iodo-, hydrochloride (1:2); (S)-3-(Azetidin-2-ylmethoxy)-5-iodopyridine dihydrochloride; 3-[(2S)-2-Azetidinylmethoxy]-5-iodopyridine dihydrochloride. Grades: ≥99% by HPLC. CAS No. 1217837-17-6. Molecular formula: C9H13IN2OCl2. Mole weight: 363.03.
5-Methoxy-2-aminotetraline hydrochloride
5-Methoxy-2-Aminotetraline hydrochloride is a dopamine receptor agonist. Synonyms: 2-amino-5-methoxytetralin HCl; 2-amino-5-methoxytetralin Hydrochloride; Aminotetraline hydrochloride, 5-Methoxy-2-; AK209995; 5-Methoxy-1,2,3,4-tetrahydro-naphthalen-2-yl amine HCl. Grades: 98%. CAS No. 3880-88-4. Molecular formula: C11H15NO.HCl. Mole weight: 213.7.
A 68930 hydrochloride
A 68930 hydrochloride is a potent and selective dopamine D1-like receptor agonist (EC50 = 2.1 and 3910 nM for D1-like and D2-like receptors, respectively). Synonyms: A-68930 hydrochloride; A 68930 hydrochloride; A68930 hydrochloride; cis-(±)-1-(Aminomethyl)-3,4-dihydro-3-phenyl-1H-2-benzopyran-5,6-diol hydrochloride; (1R,3S)-1-(aminomethyl)-3-phenyl-3,4-dihydro-1H-isochromene-5,6-diol hydrochloride. Grades: ≥98% by HPLC. CAS No. 130465-39-3. Molecular formula: C16H17NO3.HCl. Mole weight: 307.78.
A68930 hydrochloride
A68930 hydrochloride, as a dopamine D1 receptor agonist, can be used for the research of bronchiectasis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 130465-39-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg. Product ID: HY-103431.
A 77636 hydrochloride
A 77636 hydrochloride is a potent and selective dopamine D1-like receptor agonist (pEC50 = 8.97 and < 5 for D1-like and D2-like receptors, respectively). A 77636 exhibits anti-Parkinsonian activity following oral administration in vivo. Uses: Potential treatment of neurological disorders. Synonyms: A-77636 hydrochloride; A77636 hydrochloride; A77636 hydrochloride; (1R-cis)-1-(Aminomethyl)-3,4-dihydro-3-tricyclo[3.3.1.13,7]dec-1-yl-[1H]-2-benzopyran-5,6-diol hydrochloride. Grades: ≥98% by HPLC. CAS No. 145307-34-2. Molecular formula: C20H27NO3.HCl. Mole weight: 365.9.
A-77636 hydrochloride
A-77636 hydrochloride is a potent, orally active, selective and long acting dopamine D1 receptor agonist ( pK i =7.40; K i =39.8 nM) with antiparkinsonian activity. A-77636 hydrochloride is functionally inactive at dopamine D2 receptor [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 145307-34-2. Pack Sizes: 5 mg. Product ID: HY-103416.
ACR 16 hydrochloride
ACR 16 hydrochloride is a dopaminergic stabilizer (Ki values 17550 nM and 7521 for D2(low) and D2(high), respectively) that state-dependently stabilizes psychomotor activity by the dual actions of functional dopamine D2 receptor antagonism and strengthening of cortical glutamate functions in various settings of perturbed neurotransmission. ACR 16 hydrochloride is used for ameliorating several neurological and psychiatric disorders, including Huntington's disease. Uses: The treatment of neurological and psychiatric disorders. Synonyms: ACR 16 hydrochloride; ACR16 hydrochloride; ACR-16 hydrochloride; Pridopidine Hydrochloride; 4-(3-methylsulfonylphenyl)-1-propylpiperidine hydrochloride. Grades: 99%. CAS No. 882737-42-0. Molecular formula: C15H23NO2S.HCl. Mole weight: 317.87.
Adrenalone hydrochloride
Adrenalone hydrochloride is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone hydrochloride is an inhibitor of dopamine β oxidase. Adrenalone hydrochloride is chemically similar to known norepinephrine transporter (NET) ligands with an IC 50 of 36.9 μM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 62-13-5. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-B1308.
Adrogolide hydrochloride
Adrogolide hydrochloride (ABT-431 hydrochloride) is a chemically stable prodrug that can convert to the dopamine D1 receptor agonist A-86929. Adrogolide hydrochloride ameliorates the MPTP (HY-15608)-induced Parkinson's Disease in marmoset model, reduces the dyskinesias tendency. Adrogolide hydrochloride reverses Risperidone (HY-11018)-induced cognitive deficits in monkey [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ABT-431 hydrochloride; DAS-431 hydrochloride. CAS No. 166591-11-3. Pack Sizes: 1 mg. Product ID: HY-118956.
(+)-AJ 76 hydrochloride
The hydrochloride salt form of (+)-AJ 76, which is a dopamine receptor antagonist. Synonyms: (+)-AJ 76 hydrochloride; (+)-AJ76 hydrochloride; (+)-AJ-76 hydrochloride; (1S,2R)-cis-5-Methoxy-1-methyl-2-(N-propylamino)tetralin hydrochloride. Grades: ≥95% by HPLC. CAS No. 85378-82-1. Molecular formula: C15H23NO.HCl. Mole weight: 269.81.
Alizapride hydrochloride
Alizapride is a dopamine antagonist with prokinetic and antiemetic effects used in the treatment of nausea and vomiting, including postoperative nausea and vomiting. Synonyms: 6-Methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide Hydrochloride; Limican; Nausilen; Plitican; Vergentan; N-[(1-Allyl-2-pyrrolidinyl)methyl]-5-methoxy-1H-benzotriazole-6-carboxamide hydrochloride (1:1). Grades: >98%. CAS No. 59338-87-3. Molecular formula: C16H22ClN5O2. Mole weight: 351.83.
Alizapride Hydrochloride
Alizapride is a dopamine antagonist with prokinetic and antiemetic effects. Alizapride is used in t he treatment of post-operative nausea and vomitting. Group: Biochemicals. Alternative Names: 6-Methoxy-N-[[1-(2-propenyl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide Hydrochloride; Limican; Nausilen; Plitican; Vergentan. Grades: Highly Purified. CAS No. 59338-87-3. Pack Sizes: 100mg. US Biological Life Sciences.
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Amantadine Hydrochloride
Amantadine Hydrochloride is a NMDA-receptor antagonist acts as an antiviral and an antiparkinsonian drug. Uses: Dopaminergic agent. antiviral. Synonyms: 1-Adamantanamine hydrochloride; adamantan-1-amine;hydrochloride. Grades: 95%. CAS No. 665-66-7. Molecular formula: C10H18ClN. Mole weight: 187.71.
Amisulpride hydrochloride
Amisulpride hydrochloride could inhibit radioligand binding to native dopamine D2 receptor in membranes from the rat striatum with an IC50 value of 21nM. It has been revealed to displace [3H]raclopride binding in vivo with an ED50 value of 17.3±1.86mg/kg in the rat limbic system. It has been noted to inhibit quinpirole-induced [3H]thymidine with an IC50 value of 22±3nM. It is used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. It has been approved in February 2002 by FDA. Uses: Amisulpride hydrochloride is used to treat psychosis in schizophrenia and episodes of mania in bipolar disorder. Synonyms: DAN 2163 hydrochloride; DAN2163 hydrochloride; DAN-2163 hydrochloride; 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide;hydrochloride. Grades: >98%. CAS No. 81342-13-4. Molecular formula: C17H28N3O4SCl. Mole weight: 405.94.
Amisulpride hydrochloride
Amisulpride hydrochloride is a dopamine D 2 /D 3 receptor antagonist with K i s of 2.8 and 3.2 nM for human dopamine D 2 and D 3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DAN 2163 hydrochloride. CAS No. 81342-13-4. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14545A.
Amitifadine hydrochloride
Amitifadine hydrochloride is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) , with IC 50 s of 12, 23, 96 nM for serotonin, norepinephrine and dopamine in HEK 293 cells , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DOV-21947 hydrochloride; EB-1010 hydrochloride. CAS No. 410074-74-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-18332A.
Amitifadine hydrochloride
A Serotonin-Preferring Triple Reuptake Inhibitor for the Treatment of Major Depression, with the IC50 values for serotonin, norepinephrine and dopamine reuptake are 12/23/96 nM. Uses: A triple reuptake inhibitor (tri) or serotonin-norepinephrine-dopamine reuptake inhibitor (sndri). Synonyms: (1R, 5S)-1-(3, 4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane; hydrochloride; 1-(3,4-dichlorophenyl)-3-azabicyclo-(3.1.0)hexane hydrochloride. Grades: ≥98%. CAS No. 410074-74-7. Molecular formula: C11H12Cl3N. Mole weight: 264.57.
Amitriptyline-d3 hydrochloride
Amitriptyline-d3 hydrochloride is the deuterium labeled Amitriptyline (hydrochloride). Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET) , with K i s of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a K i of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic , muscarinic , histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity [1] [2] [3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 342611-00-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-135096.
Amitriptyline hydrochloride
Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET) , with K i s of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a K i of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic , muscarinic , histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 549-18-8. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-B0527A.
Amitriptyline (hydrochloride) (Standard)
Amitriptyline (hydrochloride) (Standard) is the analytical standard of Amitriptyline (hydrochloride). This product is intended for research and analytical applications. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET) , with K i s of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a K i of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic , muscarinic , histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 549-18-8. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0527AR.
Ampreloxetine hydrochloride
Ampreloxetine (TD-9855) hydrochloride is an orally active and CNS-penetrant inhibitor of Norepinephrine transporter (NET) and Serotonin 5-HT uptake transporter (SERT), but not Dopamine transporter (DAT). Ampreloxetine hydrochloride binds norepinephrine transporters (NET) and serotonin transporters (SERT) with EC 50 values of 11.7 ng/mL and 50.8 ng/mL, respectively, in plasma [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TD-9855 hydrochloride. CAS No. 1227056-87-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107128.
Ansofaxine hydrochloride
Ansofaxine hydrochloride is a triple reuptake inhibitor of serotonin (IC50 = 723 nM), dopamine (IC50 = 491 nM) and norepinephrine (IC50 = 763 nM). Synonyms: Ansofaxine HCl; LY-03005 hydrochloride; LY-03005 HCl; LY 03005 hydrochloride; LY 03005 HCl; LY03005 hydrochloride; LY03005 HCl. CAS No. 916918-84-8. Molecular formula: C24H32ClNO3. Mole weight: 417.97.
Ansofaxine hydrochloride
Ansofaxine hydrochloride (LY03005; LPM570065) is a triple reuptake inhibitor; inhibits serotonin , dopamine and norepinephrine reuptake with IC 50 values of 723, 491 and 763 nM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: LY03005; LPM570065. CAS No. 916918-84-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00096.
Asenapine hydrochloride
Asenapine hydrochloride, an antipsychotic, is a 5-HT (1A, 1B, 2A, 2B, 2C, 5A, 6, 7) and Dopamine (D 2 , D 3 , D 4 ) receptor antagonist with K i values of 0.03-4.0 nM for 5-HT and 1.3, 0.42, 1.1 nM for Dopamine receptor, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 1412458-61-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16567.
Atomoxetine hydrochloride
Atomoxetine (Tomoxetine) hydrochloride is a selective noradrenaline reuptake inhibitor with K i values of 5 nM, 77 nM and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine hydrochloride is a potent Na + channels (VGSCs) blocker. Atomoxetine hydrochloride can be used for attention-deficit hyperactivity disorder (ADHD) research [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Tomoxetine hydrochloride; (R)-Tomoxetine hydrochloride; LY 139603. CAS No. 82248-59-7. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-17385.