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| Product | Description | |
|---|---|---|
| Doxorubicin (Adriamycin, 14-Hydroxydaunomycin) | Doxorubicin is the most extensively studied of a family of highly fluorescent anthracycline antibiotics produced by several Streptomyces species, first reported in 1967 and later approved for human therapeutic use as an antitumor agent for the treatment of a wide range of cancers. Doxorubicin has also been reported to exhibit anti-HIV and antibacterial activity. The mode of action of doxorubicin is thought to be due to intercalation of DNA and inhibition of nucleic acid synthesis. Group: Biochemicals. Grades: Highly Purified. CAS No. 23214-92-8. Pack Sizes: 25mg. US Biological Life Sciences. |  Worldwide |
| Doxorubicin EP Impurity B | Doxorubicin EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-bromo-1,1-dimethoxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione. CAS No. 106401-68-7. Molecular formula: C29H34BrNO11. Mole weight: 651.13. Catalog: APB106401687. |  |
| Doxorubicin HCl | Doxorubicin HCl. Group: Biochemicals. Alternative Names: Adriamycin; (8S-cis)10-[(3-Amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy-7,8,9,10-tetrahydro-6,8,11- trihydroxy-8-(hydroacetyl)-1-methoxy-5,12- naphthacenedione. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C27H29NO11·HCl. US Biological Life Sciences. | Worldwide |
| Doxorubicin hydrochloride | 100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Organics, Research Organics & Inorganics. Formula: C27H29NO11 ·HCl. CAS No. 25316-40-9. Prepack ID 57489114-100mg. Molecular Weight 579.98. See USA prepack pricing. |  |
| Doxorubicin hydrochloride | 25mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Organics, Research Organics & Inorganics. Formula: C27H29NO11 ·HCl. CAS No. 25316-40-9. Prepack ID 57489114-25mg. Molecular Weight 579.98. See USA prepack pricing. | |
| Doxorubicin hydrochloride | Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC 50 s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Hydroxydaunorubicin hydrochloride; ADR. CAS No. 25316-40-9. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15142. |  |
| Doxorubicin hydrochloride | Doxorubicin hydrochloride Inhibitor. Uses: Scientific use. Product Category: T1020. CAS No. 25316-40-9. |  |
| Doxorubicin hydrochloride | Doxorubicin (Hydroxydaunorubicin) hydrochloride, a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 25316-40-9. Molecular formula: C27H30ClNO11. Purity: 0.9958. Product ID: ACM25316409-1. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Doxorubicin Hydrochloride | Used as an antineoplastic. Group: Biochemicals. Alternative Names: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Hydrochloride; Adriacin; Adriblastina; Adriamycin; Caelyx. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Doxorubicin, Hydrochloride (Adriacin, Adriblastina, Adriamycin, Caelyx) | The hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity. Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin. Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis. Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage. Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids; the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects. Group: Biochemicals. Alternative Names: Adriacin, Adriblastina, Adriamycin, Caelyx. Grades: Highly Purified. CAS No. 25316-40-9. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences. | Worldwide |
| Doxorubicin, Hydrochloride - CAS 25316-40-9 | Doxorubicin HCl, CAS 25316-40-9, is an antitumor antibiotic that inhibits topoisomerase II (IC?? = 100 nM). Group: Fluorescence/luminescence spectroscopy. | |
| Doxorubicin Impurity 1 | Doxorubicin Impurity 1 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Doxorubicin Impurity; 6,8,10,11-Tetrahydroxy-1-methoxy-5,12-naphthacenedione; 7,8-Desacetyl-9,10-dehydro Daunorubicinone; 5,12-Naphthacenedione, 6,8,10,11-tetrahydroxy-1-methoxy-; Xanthone Impurity 13. Grades: > 95%. CAS No. 1159977-24-8. Molecular formula: C19H12O7. Mole weight: 352.29. |  |
| Doxorubicin Impurity 2 | Doxorubicin Impurity 2 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Doxorubicin Impurity-?; 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione; 5,12-Naphthacenedione, 6,8,11-trihydroxy-1-methoxy-; 7,8-Dehydro-9,10-desacetyldoxorubicinone; 7,8-Dhda-DR; 1-Methoxy-6,8,11-trihydroxynaphthacene-5,12-dione. Grades: >95%. CAS No. 64845-67-6. Molecular formula: C19H12O6. Mole weight: 336.30. | |
| Doxorubicin Impurity 6 | Doxorubicin Impurity 6 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: 9-Carboxy Doxorubicin Impurity; (2S,4S)-4-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-2-carboxylic acid; (2S,4S)-4-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenecarboxylic Acid; 2-Naphthacenecarboxylic acid, 4-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-, (2S-cis)-; 8-Desacetyl-8-carboxy Daunorubicin. Grades: > 95%. CAS No. 69429-21-6. Molecular formula: C26H27NO11. Mole weight: 529.49. | |
| Doxorubicin Impurity 7 | Doxorubicin Impurity 7 is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: 7,8,9,10-Dehydro Doxorubicinone; 8-Glycoloyl-6,10,11-trihydroxy-1-methoxy-5,12-tetracenedione; 5,12-Naphthacenedione, 6,10,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-; 6,10,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxytetracene-5,12-dione. Grades: > 95%. CAS No. 1159977-23-7. Molecular formula: C21H14O8. Mole weight: 394.33. | |
| Doxorubicin Impurity 7 | Doxorubicin Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6,11-dihydroxy-8-(2-hydroxyacetyl)-1-methoxytetracene-5,12-dione. CAS No. 105612-58-6. Molecular formula: C21H14O7. Mole weight: 378.07. Catalog: APB105612586. | |
| Doxorubicin Impurity B | Cas No. 106401-68-7. | |
| Doxorubicin Liposome (PEGylated) | This formulation of doxorubicin liposome is PEGylated, which is only for research purposes and for the injection to laboratory animals. Doxorubicin drug is encapsulated into the liposome using remote loading by ammonium sulfate gradient. The formulation is ready for injection. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. |  |
| Doxorubicinol Citrate (Mixture of Diastereomers) | A metabolite of Doxorubicin as neoplasm inhibitor. Group: Biochemicals. Alternative Names: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-[1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Citrate. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Doxorubicinol hydrochloride | Doxorubicinol hydrochloride (13-Dihydroadriamycin hydrochloride) is a secondary alcohol metabolite of Doxorubicin [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 13-Dihydroadriamycin hydrochloride. CAS No. 63950-05-0. Pack Sizes: 1 mg. Product ID: HY-G0022. | |
| Doxorubicinol hydrochloride | Doxorubicinol is the major metabolite of doxorubicin, which inhibits DNA topoisomerase II by inducing double-stranded DNA breaks. Synonyms: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-[(1S)-1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione Hydrochloride; Adriamycinol Hydrochloride; 13-Dihydrodoxorubicin Hydrochloride; (1S,3S)-3-[(1S)-1,2-Dihydroxyethyl]-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside hydrochloride (1:1); 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-[(1S)-1,2-dihydroxyethyl]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S)-, hydrochloride (1:1). Grades: ≥90%. CAS No. 63950-05-0. Molecular formula: C27H31NO11.HCl. Mole weight: 582.00. | |
| Doxorubicinol Hydrochloride (>90%)(Mixture of diastereomers) | | |
| Doxorubicinol Hydrochloride. (Mixture of diastereomers). | Doxorubicinol Hydrochloride(Mixture of diastereomers). Group: Biochemicals. Grades: Highly Purified. CAS No. 63950-05-0. Pack Sizes: 2mg. US Biological Life Sciences. | Worldwide |
| Doxorubicinolone (Mixture of Diastereomers) | A metabolite of Epirubicin. Group: Biochemicals. Alternative Names: (8S,10S)-. Grades: Highly Purified. CAS No. 56149-23-6. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Doxorubicinolone (Mixture of Diastereomers) | Doxorubicinolone (Mixture of Diastereomers) is a metabolite of Epirubicin, which is an anthracycline topoisomerase inhibitor used as an antineoplastic agent. Synonyms: (8S,10S)-8-(1,2-Dihydroxyethyl)-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-5,12-naphthacenedione; (8S,10S)-8-(1,2-Dihydroxyethyl)-6,8,10,11-tetrahydroxy-1-methoxy-7,8,9,10-tetrahydro-5,12-tetracenedione; 5,12-Naphthacenedione, 8-(1,2-dihydroxyethyl)-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-, (8S,10S)-. Grades: ≥95%. CAS No. 210837-88-0. Molecular formula: C21H20O9. Mole weight: 416.39. | |
| Doxorubicinone | Cas No. 24385-10-2. | |
| Doxorubicinone | Doxorubicinone. Group: Biochemicals. Alternative Names: (8S,10S)-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 24385-10-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C21H18O9. US Biological Life Sciences. | Worldwide |
| Doxorubicinone (Adriamycinone, Doxorubicin aglycone) | Doxorubicinone (Adriamycinone, Doxorubicin aglycone). Group: Biochemicals. Alternative Names: Adriamycinone, Doxorubicin aglycone. Grades: Highly Purified. CAS No. 24385-10-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 11-Deoxydoxorubicin | 11-Deoxydoxorubicin is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-8,11-dihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)-; (1S,3S)-3-Glycoloyl-3,12-dihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; (8S-cis)-10-((3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-8,11-dihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; 11-Deoxyadriamycin. Grades: ≥95%. CAS No. 71800-89-0. Molecular formula: C27H29NO10. Mole weight: 527.52. | |
| 3-N-Carboxylic Acid 1- β -D-Glucuronide-[4- (methyl) phenyl]carbamate Ester Doxorubicin | 3-N-Carboxylic Acid 1- β -D-Glucuronide-[4- (methyl) phenyl]carbamate Ester Doxorubicin. Group: Biochemicals. Alternative Names: (8S,10S)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[4-[[( β -D-glucopyranuronosyloxy) carbonyl] amino] phenyl] methoxy] carbonyl] amino] -α -L-lyxo-hexopyranosyl] oxy] -5, 12-naphthacenedione. Grades: Highly Purified. CAS No. 211364-63-5. Pack Sizes: 1mg. Molecular Formula: C42H44N2O21, Molecular Weight: 912.8. US Biological Life Sciences. | Worldwide |
| 4-O-Des methyl doxorubicinone | Doxorubicinone analogs. Group: Biochemicals. Alternative Names: (8S-cis)-7,8,9,10-Tetrahydro-1,6,8,10,11-pentahydroxy-8-(hydroxyacetyl)-5,12-naphthacenedione; (8S,10S)-7,8,9,10-Tetrahydro-1,6,8,10,11-pentahydroxy-8-(hydroxyacetyl)-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 65446-19-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione (Doxorubicin Impurity) | 6,8,11-Trihydroxy-1-methoxy-5,12-naphthacenedione (Doxorubicin Impurity). Uses: For analytical and research use. Group: Impurity standards. CAS No. 64845-67-6. Molecular formula: C19H12O6. Mole weight: 336.30. Catalog: APS64845676. Format: Neat. | |
| 7,8-Desacetyl-9,10-dehydro Daunorubicinone (~90%) (Doxorubicin Impurity) | 7,8-Desacetyl-9,10-dehydro Daunorubicinone (~90%) (Doxorubicin Impurity). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6,8,10,11-Tetrahydroxy-1-methoxy-5,12-naphthacenedione, 7,8-Desacetyl-9,10-dehydro Daunorubicinone, Doxorubicin Impurity,6,8,10,11-Tetrahydroxy-1-methoxy-5,12-naphthacenedione. CAS No. 1159977-24-8. IUPAC Name: 1,3,6,11-tetrahydroxy-10-methoxytetracene-5,12-dione. Molecular formula: C19H12O7. Mole weight: 352.29. Catalog: APS1159977248. SMILES: COc1cccc2c(O)c3C(=O)c4cc(O)cc(O)c4C(=O)c3c(O)c12. Format: Neat. | |
| 7,8-Desacetyl-9,10-dehydro Daunorubicinone (~90%)(Doxorubicin Impurity) | 7,8-Desacetyl-9,10-dehydro Daunorubicinone (~90%)(Doxorubicin Impurity). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1159977-24-8. Pack Sizes: 5MG. IUPAC Name: 1,3,6,11-tetrahydroxy-10-methoxytetracene-5,12-dione. Molecular formula: C19H12O7. Mole weight: 352.29. Catalog: APS1159977248A. SMILES: COc1cccc2c(O)c3C(=O)c4cc(O)cc(O)c4C(=O)c3c(O)c12. Format: Neat. Shipping: Room Temperature. | |
| 7,8-Desacetyl-9,10-dehydro Daunorubicinone (Doxorubicin Impurity) | Potential degradation product of Doxorubicin. Doxorubicin impurity. Group: Biochemicals. Alternative Names: Doxorubicin Impurity; 6,8,10,11-Tetrahydroxy-1-methoxy-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 1159977-24-8. Pack Sizes: 500ug. Molecular Formula: C??H??O?, Molecular Weight: 352.29. US Biological Life Sciences. | Worldwide |
| 7-Deoxy Doxorubicin Aglycone | A metabolite of Doxorubicin (Dx). Group: Biochemicals. Alternative Names: (8R)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione; 7-Deoxyadriamycin Aglycone; 7-Deoxyadriamycinone; 7-Deoxydoxorubicinone; 7-Deoxyepirubicin Aglycone; NSC 270536. Grades: Highly Purified. CAS No. 38554-25-5. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| 7-Deoxy Doxorubicinol Aglycone (Mixture of Diastereomers) | A metabolite of Doxorubicin. Group: Biochemicals. Alternative Names: (8R)-8-(1,2-Dihydroxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 187105-52-8. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione-d6. (Doxorubicin Impurity) | (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione-d6(Doxorubicin Impurity). Group: Biochemicals. Alternative Names: (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione-d6. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C29H28D6BrNO11, Molecular Weight: 658.52. US Biological Life Sciences. | Worldwide |
| (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione. (Doxorubicin Impurity) | (8S, 10S)-10-[ (3-Amino-2, 3, 6-trideoxy-α -L-lyxo-hexopyranosyl)oxy]-8- (2-bromo-1, 1-dimethoxyethyl)-7, 8, 9, 10-tetrahydro-6, 8, 11-trihydroxy-1-methoxy-5, 12-naphthacenedione (Doxorubicin Impurity). Group: Biochemicals. Alternative Names: (8S-cis)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione. Grades: Highly Purified. CAS No. 106401-68-7. Pack Sizes: 10mg. Molecular Formula: C29H34BrNO11, Molecular Weight: 652.48. US Biological Life Sciences. | Worldwide |
| 9,10-Anhydro doxorubicin | 9,10-Anhydro doxorubicin is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Doxorubicin Impurity 8; 9,10-Anhydroadriamycin; (1S)-3-Glycoloyl-5,12-dihydroxy-10-methoxy-6,11-dioxo-1,2,6,11-tetrahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; 9,10-Anhydrodoxorubicin; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-9,10-dihydro-6,11-dihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (10S)-; (S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-9,10-dihydro-6,11-dihydroxy-8-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione. Grades: ≥95%. CAS No. 80996-23-2. Molecular formula: C27H27NO10. Mole weight: 525.50. | |
| Aldoxorubicin | Aldoxorubicin (INNO-206) is an albumin-binding proagent of Doxorubicin (DNA topoisomerase II inhibitor), which is released from albumin under acidic conditions. Aldoxorubicin (INNO-206) has potent antitumor activities in various cancer cell lines and in murine tumor models. Uses: Scientific research. Group: Signaling pathways. Alternative Names: INNO-206; DOXO-EMCH. CAS No. 1361644-26-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16261. | |
| Amine-Doxorubicin Liposome (PEGylated) | This formulation is Doxorubicin Liposome (PEGylated) with the amine group, which can react with peptides, antibodies and other NHS-containing biomolecules or nanoparticles. The free carboxyl group on the antibody, peptide or protein can be activated by EDC/sulfo-NHS, and then covalently conjugated to the lipids through displacement of sulfo-NHS groups by amine groups of the liposome. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| Azide-Doxorubicin Liposome (PEGylated) | This formulation is Doxorubicin Liposome (PEGylated) with the azide group, which can react with an dibenzocyclooctyne (DBCO) by click chemistry. The conjugation chemistry is based on the reaction of the azide reagent with an DBCO linker to form a stable triazole. DBCO moiety can be on the antibody and azide moiety can be on liposome and vice versa. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| Biotin-Doxorubicin Liposome (PEGylated) | This formulation is Doxorubicin Liposome (PEGylated) with the biotin group. Biotinylated liposome can be conjugated noncovalently with (strept)avidin through either direct interaction with the protein/antibody conjugated to (strept)avidin or by coupling with other biotinylated proteins using (strept)avidin as a bridging molecule. Both avidin and (strept)avidin form strong noncovalent bond with biotin. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| Carboxylic Acid-Doxorubicin Liposome (PEGylated) | This formulation is Doxorubicin Liposome (PEGylated) with the carboxyl group, which can be activated by EDC (1-ethyl-3-[3-dimethylaminopropyl] carbodiimide) and react with sulfo-NHS (N-hydroxysulfosuccinimide) to produce a significantly more stable and more soluble active intermediate (NHS ester). The intermediate can covalently conjugate to the amine group on the proteins, peptides or antibodies through displacement of sulfo-NHS group by amine. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| Control Doxorubicin Liposome (PEGylated) | Control Doxorubicin Liposome (PEGylated) is a control formulation for PEGylated doxorubicin liposome. The formulation is similar to PEGylated doxorubicin liposome in size and lipid composition, but it does not contain doxorubicin drug. It is only for research purposes and for the injection to laboratory animals. The formulation is made in ammonium sulfate gradient and it is ready for injection. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| Cyanur-Doxorubicin Liposome (PEGylated) | This formulation is Doxorubicin Liposome (PEGylated) with the cyanur group. Proteins can be covalently coupled to the liposome via amine-reactive cyanur-groups, either directly to the vesicle surface using cyanuric chloride-activated DSPE (cyanur-DSPE) or to the distal ends of PEG-spacers using activated cyanur-PEG-PE (ammonium salt). Cyanuric chloride at the PEG terminus functions to link peptides, antibodies and other amine-containing biomolecules or nanoparticles via a nucleophilic substitution reaction under basic conditions. Antibodies or other proteins can be conjugated without any previous derivatization. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| Daunorubicin EP Impurity D (Doxorubicin) | Doxorubicin is an anthracycline antibiotic produced in Str. peucetius var. caesinus. Doxorubicin has anti-Gram-positive bacteria activity and has a broad anti-tumor spectrum. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis. Uses: Adcs cytotoxin. Synonyms: (8S,10S)-10-[(3-amino-2,3,6-trideoxy-α-L-lyxohexopyranosyl)oxy]-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Adriamycin; Doxil; Adriablastin; Doxorubicine; Adriblastina; 14-Hydroxydaunomycin; 14-Hydroxydaunorubicine; Caelyx; Hydroxydaunorubicin; NSC-759155; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-; NSC-123127; (1S,3S)-3,5,12-trihydroxy-3-(hydroxyacetyl)-10-(methyloxy)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-1-yl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranoside; Epirubicin EP Impurity C. Grades: >98%. CAS No. 23214-92-8. Molecular formula: C27H29NO11. Mole weight: 543.52. | |
| DBCO-Doxorubicin Liposome (PEGylated) | This formulation is Doxorubicin Liposome (PEGylated) with the dibenzocyclooctyne (DBCO) group, which can react with an azide by click chemistry. The conjugation chemistry is based on the reaction of the DBCO reagent with an azide linker to form a stable triazole. Azide moiety can be on the antibody and DBCO moiety can be on liposome and vice versa. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| Desmethyl doxorubicin (14-Hydroxycarminomycin) | Desmethyl doxorubicin is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(hydroxyacetyl)-5,12-naphthacenedione; Desmethyldoxorubicin; (1S,3S)-3-Glycoloyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(hydroxyacetyl)-, (8S-cis)-; 14-Hydroxy Carminomycin. Grades: > 95%. CAS No. 69401-50-9. Molecular formula: C26H27NO11. Mole weight: 529.51. | |
| Folate-Doxorubicin Liposome (PEGylated) | This formulation is Doxorubicin Liposome (PEGylated) with the folate. Folate binding protein (FBP) is an endogenous protein, which shows a very high affinity for folate. An antibody can be tagged by FBP and an immunoliposome can be formed by non-covalent and high affinity interaction between FBP and folate lipid on the surface of the liposome. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| N- (9-Fluorenyl methoxycarbonyl ) -4, 6, 8, 11-tetra-O-benzoyl Doxorubicin | N- (9-Fluorenyl methoxycarbonyl ) Doxorubicin derivative. Used in the preparation of a modified Doxorubicin (ANG1007) and Etoposide (ANG1009) useful due to their brain penetration ability. Group: Biochemicals. Alternative Names: (8S, 10S) -7, 8, 9, 10-tetrahydro-8-hydroxy-6, 11-dibenzoyloxy-8- (2-benzoyloxyacetyl) -1-methoxy-10-[[2, 3, 6-trideoxy-3-[[ (9H-fluoren-9-ylmethoxy) carbonyl]amino]-4-benzyloxy-α -L-lyxo-hexopyranosyl]oxy]-5, 12-naphthacenedione. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| N- (9-Fluorenyl methoxycarbonyl ) Doxorubicin | Used in the preparation of a modified Doxorubicin (ANG1007) and Etoposide (ANG1009), useful due to their brain penetration ability. Group: Biochemicals. Alternative Names: (8S, 10S) -7, 8, 9, 10-tetrahydro-6, 8, 11-trihydroxy-8- (2-hydroxyacetyl) -1-methoxy-10-[[2, 3, 6-trideoxy-3-[[ (9H-fluoren-9-ylmethoxy) carbonyl]amino]-α -L-lyxo-hexopyranosyl]oxy]-5, 12-naphthacenedione. Grades: Highly Purified. CAS No. 136582-53-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| N-Trifluoroacetyl-4-nitobenzoate-8-(2-acetyloxy) Doxorubicin | Doxorubicin derivative. Group: Biochemicals. Alternative Names: N-Trifluoroacetyl-4-nitobenzoate-8-(2-acetyloxy)adriamycin. Grades: Highly Purified. Pack Sizes: 250ug. US Biological Life Sciences. | Worldwide |
| N-Trifluoroacetyl-8- (2-tert-butyl (dimethyl)silyl]oxy) Doxorubicin | Doxorubicin metabolite. Cytotoxic interaction with DNA. Group: Biochemicals. Alternative Names: N-Trifluoroacetyl-8- (2-tert-butyl (dimethyl) silyl]oxy) adriamycin; (1S, 3S) -2, 3, 6-Trideoxy-3- (2, 2, 2-trifluoroacetamido) -3-ert-butyl (dimethyl) silylglycoloyl-1, 2, 3, 4, 6, 11-hexahydro-3, 5, 12-trihydroxy-10-methoxy-6, 11-dioxo-1-naphthacenyl-α -L-lyxo-hexopyranoside. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-tri fluoroacetyl doxorubicin | Doxorubicin metabolite. Cytotoxic interaction with DNA. Group: Biochemicals. Alternative Names: N-tri fluoroacetyl adriamycin; NSC 283464; (8S-cis) -7, 8, 9, 10-Tetrahydro-6, 8, 11-trihydroxy-8- (hydroxyacetyl) -1-methoxy-10-[[2, 3, 6-trideoxy-3-[ (trifluoroacetyl) amino]-α -L-lyxo-hexopyranosyl]oxy]-5, 12-naphthacenedione; (1S,3S)- α-2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido)-3-glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl L-lyxo-Hexopyranoside. Grades: Highly Purified. CAS No. 26295-56-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| N-Trifluoroacetyl Doxorubicin | N-Trifluoroacetyl Doxorubicin is a metabolite of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: N-Trifluoroacetyladriamycin; NSC 283464; (8S-cis)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione; (1S,3S)-α-2,3,6-trideoxy-3-(2,2,2-trifluoroacetamido)-3-glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl L-lyxo-Hexopyranoside; 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[(2,2,2-trifluoroacetyl)amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-. Grades: >95%. CAS No. 26295-56-7. Molecular formula: C29H28F3NO12. Mole weight: 639.53. | |
| PDP-Doxorubicin Liposome (PEGylated) | This formulation is Doxorubicin Liposome (PEGylated) with the pyridyldithiopropionate (PDP) group. The liposome containing PDP lipids are used to conjugate proteins, antibodies and other molecules containing the reactive moiety. The PDP group contains disulfide, which can react with sulfhydryl or thiolated proteins/antibodies. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| Succinyl-Doxorubicin Liposome (PEGylated) | This formulation is Doxorubicin Liposome (PEGylated) with the carboxyl group, which can be activated by EDC (1-ethyl-3-[3-dimethylaminopropyl] carbodiimide) and react with sulfo-NHS (N-hydroxysulfosuccinimide) to produce a significantly more stable and more soluble active intermediate (NHS ester). The intermediate can covalently conjugate to the amine group on the proteins, peptides or antibodies through displacement of sulfo-NHS group by amine. Group: Drug-loaded liposome. Categories: liposomes, niosomes, ethosomes, and transfersomes. | |
| 1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt | 1,2-Distearoyl-sn-glycero-3-phospho-rac-(1-glycerol) Sodium Salt is used to prepare polyethyleneglycol-modified liposomal doxorubicin for therapies against drug resistant tumors. It is also used in the PEGylated liposomal drug formulation of the anti-cancer agent oxaliplatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 200880-42-8. Pack Sizes: 10mg, 25mg. Molecular Formula: C42H82NaO10P. US Biological Life Sciences. | Worldwide |
| 14-Bromodaunorubicin hydrochloride | 14-Bromodaunorubicin hydrochloride is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. Synonyms: Doxorubicin EP Impurity C hydrochloride; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(bromoacetyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione hydrochloride; L-lyxo-Hexopyranoside, 3-(bromoacetyl)-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-, hydrochloride, (1S,3S)-α-; 14-Bromodaunomycin hydrochloride; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-8-(bromoacetyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S-cis)-, hydrochloride (1:1). Grades: ≥95%. CAS No. 29742-67-4. Molecular formula: C27H29BrClNO10. Mole weight: 642.88. | |
| 14-Bromo-N-trifluoroacetamido Daunorubicin Hydrobromide Salt | 14-Bromo-N-trifluoroacetamido Daunorubicin Hydrobromide Salt is an intermediate in the synthesis of Doxorubicin Dimer Impurity 1which is an is an impurity of Doxorubicin Hydrochloride (D558000), an antineoplastic. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C29H27BrF3NO11. US Biological Life Sciences. | Worldwide |
| 1,4-Di-O-butanoyl-2,3:5,6-di-O-isopropylidene-D-myo-inositol | 1,4-Di-O-butanoyl-2,3:5,6-di-O-isopropylidene-D-myo-inositol is a complex chemical compound widely employed in the pharmaceutical industry. It is an essential building block for a multitude of drugs with diverse antitumor activities, including the potent 4-epi-doxorubicin and daunorubicinone. Impressively, this versatile compound can also facilitate the synthesis of potent antiviral and antibacterial agents, thus making it a vital component for modern-day pharmaceutical research and development. Synonyms: (3AR,4S,4aS,7aS,8S,8aS)-2,2,6,6-tetramethylhexahydrobenzo[1,2-d:4,5-d']bis([1,3]dioxole)-4,8-diyl dibutyrate; [(1S,3R,7S,9S)-8-butanoyloxy-5,5,11,11-tetramethyl-4,6,10,12-tetraoxatricyclo[7.3.0.03,7]dodecan-2-yl] butanoate. CAS No. 1620222-02-7. Molecular formula: C20H32O8. Mole weight: 400.46. | |
| 14-Hydroxy Carminomycin Oxalate | 14-Hydroxy Carminomycin Oxalate is an impurity of Doxorubicin, which is an anthracycline antibiotic with anti-Gram-positive bacterial activity and a broad antitumor spectrum. It is also a semisynthetic analog of Carminomycin with cytostatic activity. Synonyms: (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(hydroxyacetyl)-5,12-naphthacenedione Oxalate; Desmethyldoxorubicin Oxalate; (1S,3S)-3-Glycoloyl-3,5,10,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside Oxalate; 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-1,6,8,11-tetrahydroxy-8-(hydroxyacetyl)-, (8S-cis)-, Oxalate (1:1). Grades: 90%. Molecular formula: C28H29NO15. Mole weight: 619.53. | |
| 2-[2- (Fmoc-amino) ethoxy]ethylamine Hydrochloride | 2-[2- (Fmoc-amino) ethoxy]ethylamine is an intermediate used to synthesize specific probes for human 5-HT4 receptor dimerization studies. It is also used to prepare doxorubicin-formaldehyde peptide conjugates targeting αv β3 integrin with antitumor activities. Group: Biochemicals. Grades: Highly Purified. CAS No. 221352-88-1. Pack Sizes: 25mg, 50mg. Molecular Formula: C19H23ClN2O3, Molecular Weight: 362.85. US Biological Life Sciences. | Worldwide |
| (2S,4S)-4-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenecarboxylic Acid. (90%) | (2S,4S)-4-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-2-naphthacenecarboxylic Acid is an impurity of Doxorubicin (D558000), an antineoplastic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 69429-21-6. Pack Sizes: 25mg, 100mg. Molecular Formula: C26H27NO11. US Biological Life Sciences. | Worldwide |
| 3-Allyloxy-1,2-propanediol | 3-Allyloxy-1,2-propanediol is a useful synthetic intermediate. It is used to prepare doxorubicin analogs. It is also used to synhesize poly(ethylene glycol)-lipid conjugates suitable for use in drug delivery. Group: Biochemicals. Grades: Highly Purified. CAS No. 123-34-2. Pack Sizes: 1g, 5g. Molecular Formula: C6H12O3, Molecular Weight: 132.16. US Biological Life Sciences. | Worldwide |
| 3-Allyloxy-1,2-propanediol-d5 | 3-Allyloxy-1,2-propanediol-d5 is labelled 3-Allyloxy-1,2-propanediol (A569020) which is used to prepare doxorubicin analogs. It is also used to synhesize poly(ethylene glycol)-lipid conjugates suitable for use in drug delivery. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C6H7D5O3, Molecular Weight: 137.19. US Biological Life Sciences. | Worldwide |
| 4'-Acetylchrysomycin B | 4'-Acetylchrysomycin B is a bacterial metabolite of chrysomycin B which has been found in Streptomyces and it has antibacterial and anticancer activities. It is active against strains of B. subtilis, B. cereus, Corynebacterium bovis, and E. faecalis (MICs = 2-64 μg/ml). 4'-Acetylchrysomycin B is also cytotoxic against a panel of human cancer cell lines, including doxorubicin-sensitive or -resistant cells (IC50s = 1.7-14 and 260-370 ng/ml, respectively). Synonyms: 4'-acetylchrysomycin B; Acetylchrysomycin A, 4'-; PD143424. Grades: >95% by HPLC. Molecular formula: C29H30O10. Mole weight: 538.54. | |
| 4-Epi-daunosamine | 4-Epi-daunosamine is an essential compound widely utilized in the biomedical field, holding immense significance in research of a plethora of diseases, particularly cancer. In the realm of chemotherapy, it serves as an indispensable precursor, facilitating the research and development of influential antibiotics, namely daunorubicin and doxorubicin. Synonyms: L-arabino-Hexose, 3-amino-2,3,6-trideoxy- Acosamine. CAS No. 41094-24-0. Molecular formula: C6H11NO3. Mole weight: 145.16. | |
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