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| Product | Description | |
|---|---|---|
| DQP-1105 | DQP-1105 is a potent noncompetitive NMDA receptor antagonist. DQP-1105 inhibits GluN2C- and GluN2D-containing receptors ( IC 50 =7.0 and 2.7 μM, respectively). The IC 50 values are at least 50-fold lower than those for recombinant GluN2A-, GluN2B-, GluA1-, or GluK2-containing receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 380560-89-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-107711. |  |
| NMDAR2C/2D Inhibitor, DQP-1105 | The NMDAR2C/2D Inhibitor, DQP-1105 controls the biological activity of NMDAR2C/2D. This small molecule/inhibitor is primarily used for Neuroscience applications. Group: Fluorescence/luminescence spectroscopy. |  |
| NMDAR2C/2D Inhibitor, DQP-1105 (DQP-1105, NMDA Antagonist IV) | A dihydroquinilone-pyrazoline NMDA antagonist, which is selective for NMDA receptors that are comprised of recombinant subunits GluN1/GluN2C (IC50 = 5.4uM) and GluN1/GluN2D (2.2uM) over GluN1/GluN2B (206uM) and GluN1/ClucN2A (undetectable) in Xenopus oocytes. Similar selectivity is observed in whole-cell HEK patch-clamp assays with IC50 values for GluN2C and GluN2D that are at least 50-fold lower than those for recombinant GluN2A, GluN2B, GluA1, or GluK2-containing receptors. It inhibits NMDA by blocking a conformational change necessary for channel opening and is non-competitive with co-agonists, glutamate and glycine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-Pyrazole-1-butanoic Acid | 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-Pyrazole-1-butanoic Acid. Group: Biochemicals. Alternative Names: 4-(5-(4-bromophenyl)-3-(6-methyl-2-oxo-4-phenyl-1,2-dihydroquinolin-3-yl)-4,5-dihydro-1H-pyrazol-1-yl)-4-oxobutanoic Acid; DC 060015; DQP-1105. Grades: Highly Purified. CAS No. 380560-89-4. Pack Sizes: 10mg. Molecular Formula: C29H24BrN3O4, Molecular Weight: 558.419999999999. US Biological Life Sciences. | Worldwide |
| DQP 1105 | DQP 1105 has been found to be a NMDA receptor antagonist and could exhibit potential activities in the treatment of neurological disability. Synonyms: DQP-1105; DQP 1105; DQP1105; 5-(4-Bromophenyl)-3-(1,2-dihydro-6-methyl-2-oxo-4-phenyl-3-quinolinyl)-4,5-dihydro-γ-oxo-1H-pyrazole-1-butanoic acid. Grades: ≥97% by HPLC. CAS No. 380560-89-4. Molecular formula: C29H24BrN3O4. Mole weight: 558.42. |  |
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