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Droloxifene, a Tamoxifen derivative, is an orally active and selective estrogen receptor modulator. Droloxifene shows antiestrogenic and anti-implantation effects. Droloxifene induces p53 expression and apoptosis in MCF-7 cells. Droloxifene prevents bone loss in ovariectomized rats [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 3-Hydroxytamoxifen. CAS No. 82413-20-5. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-121149.
Droloxifene citrate
Droloxifene citrate. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (E)-[2-[4-[1-(3-hydroxyphenyl)-2-phenylbut-1-enyl]phenoxy]ethyl]dimethylammonium dihydrogen 2-hydroxypropane-1,2,3-tricarboxylate;(E)-1-(4'-(2-Dimethylaminoethoxy)phenyl)-1-(3-hydroxyphenyl)-2-phenylbut-1-ene citrate;Droloxifene citrate. Product Category: Heterocyclic Organic Compound. CAS No. 97752-20-0. Molecular formula: C26H29NO2.C6H8O7. Mole weight: 579.64. Product ID: ACM97752200. Alfa Chemistry ISO 9001:2015 Certified.
Droloxifene citrate
(E)-3-hydroxy-tamoxifen. anti-estrogen, anti-hyperlipoproteinemic, reduces bone loss. CAS No. 82413-20-5. Product ID: 1-01037. Molecular formula: C26H29NO2. C6H8O7. Mole weight: 579.65. Properties: solubility in water 0.5mg/mL. Reference: J. Med. Chem. 42, 1, 1999; Bone, 20, 31, 1997; Endocrinology, 136, 2435, 1995; Breast Cancer Res. Treat., 31, 83, 1994; Cancer Lett., 82, 89, 1994.
N-Desmethyl Droloxifene (contains up to 5% Z isomer)
A metabolite of Droloxifene. Group: Biochemicals. Alternative Names: 3-[ (1E) -1-[4-[2- (Methylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol; N-Desmethyldroloxifene; K 106; N-Desmethyl-3-Hydroxytamoxifen. Grades: Highly Purified. CAS No. 83647-33-0. Pack Sizes: 1mg. US Biological Life Sciences.
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N-Desmethyl Droloxifene-d5
A labeled metabolite of Droloxifene. Group: Biochemicals. Alternative Names: 3-[ (1E) -1-[4-[2- (Methylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl-d5]-phenol; N-Desmethyldroloxifene-d5; K 106-d5;N-Desmethyl-3-hydroxytamoxifen-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Acolbifene
Acolbifene, also known as EM-652, or SCH-57068, is a selective estrogen receptor modulator (SERM). Acolbifene is currently being studied in the prevention of breast cancer in women at high risk of breast cancer. EM-652 is the compound having the highest affinity for the estrogen receptor, including estradiol. It has higher affinity for the ER than ICI 182780, hydroxytamoxifen, raloxifene, droloxifene and hydroxytoremifene. EM-652 was also the most potent inhibitor of the percentage of cycling cancer cells. Synonyms: EM-652; SCH 57068; (2S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; (S)-3-(4-Hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-2H-1-benzopyran-7-ol; (S)-3-(4-hydroxyphenyl)-4-methyl-2-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-2H-chromen-7-ol. Grades: ≥98%. CAS No. 182167-02-8. Molecular formula: C29H31NO4. Mole weight: 457.57.
(E)-3-Hydroxy tamoxifen
(E)-3-Hydroxy tamoxifen. Group: Biochemicals. Alternative Names: 3-[ (1E) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol; Droloxifene; E-Droloxifene. Grades: Highly Purified. CAS No. 82413-20-5. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C26H29NO2. US Biological Life Sciences.
Worldwide
(E)-3-Hydroxy Tamoxifen-d5
A labeled Tamoxifen derivative with antitumor effect on estrogen-dependent breast cancer cells. Group: Biochemicals. Alternative Names: 3-[ (1E) -1-[4-[2- (Dimethylamino) ethoxy]phenyl]-2-phenyl-1-buten-1-yl-d5]phenol; Droloxifene-d5; E-Droloxifene-d5; K-060-d5; K060E-d5; K 21.060E-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
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