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| Product | Description | |
|---|---|---|
| DSM265 | DSM265 is a long-duration inhibitor of P. falciparum dihydroorotate dehydrogenase ( Pf DHODH ) with an IC 50 of 8.9 nM. DSM265 can also inhibit the growth of Pf 3D7 parasites with an EC 50 of 4.3 nM [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1282041-94-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-100184. |  |
| DSM265 | DSM265 is a selective DHODH (dihydroorotate dehydrogenase) inhibitor used for prevention and treatment of malaria. DSM265 is highly selective toward DHODH of the malaria parasite Plasmodium. It is efficacious against both blood and liver stages of P. falciparum and active against drug-resistant parasite isolates. Treatment for malaria was in phase II clinical trials. Uses: Malaria. Synonyms: DSM265; DSM-265; DSM 265; UNII-0Q42P4YI6B; 0Q42P4YI6B; CHEMBL1956285; SCHEMBL14053411;2-(1,1-difluoroethyl)-5-methyl-N-[4-(pentafluoro-$l^{6}-sulfanyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine. Grades: 98%. CAS No. 1282041-94-4. Molecular formula: C14H12F7N5S. Mole weight: 415.34. |  |
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