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| Product | Description | |
|---|---|---|
| Dynasore | Dynamin GTPase inhibitor. Endocytosis inhibitor. Viral infection inhibitor. Destabilizes actin filaments. Inhibits entry of Trypanosoma into macrophages. Group: Biochemicals. Grades: Highly Purified. CAS No. 304448-55-3. Pack Sizes: 5mg, 25mg. Molecular Formula: C18H14N2O4. 0.5H2O. US Biological Life Sciences. |  Worldwide |
| Dynasore | Dynasore is a cell-permeable and noncompetitive inhibitor of the GTPase activity of dynamin with IC50 value of 15 μM. Synonyms: Dynasore. Grades: >98%. CAS No. 304448-55-3. Molecular formula: C18H14N2O4. Mole weight: 322.31. |  |
| Hydroxy Dynasore | Hydroxy Dynasore. Group: Biochemicals. Grades: Purified. CAS No. 1256493-34-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Hydroxy-Dynasore | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Dynamin Inhibitor V, 34-2 (2-Cyano-N-octyl-3-(1-(3-dimethylaminopropyl)-1H-indol-3-yl)-acrylamide) | A cell-permeable, allosteric Dynamin inhibitor (IC50=6.9uM and 14uM for full length Dynamin I and Dynamin II GTPase activity, respectively, in vitro). 10uM of this compound results in cytokinesis failure at the abscission stage in HeLa cultures, with 82% of cells that enter into mitosis becoming multinucleated, and with 97% resulting in cell death. However, it displays a much reduced effect in NIH3T3 cells at the same concentration. It elicits a dose-dependent reduction in cell growth against SMA-560, SJ-G2, SW480, MCF-7 and A2780 cultures, as being the most sensitive among a panel of other cancer cell lines (GI50=4.0 - 37uM). It was further shown to be 6-fold more active (IC50=5.0uM) than dynamin mediated receptor mediated endocytosis (RME) in U2OS cells, and 15-fold more active (IC50=1.3uM) than Dynasore in another Dynamin I GTPase activity assay. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Dyngo-4a | Dyngo-4a is a potent dynamin inhibitor with IC50 of 0.38 μM, 1.1?μM, and 2.3 μM for DynI (brain), DynI (rec), and DynII (rec), respectively. Synonyms: Hydroxy-Dynasore; 2-Naphthalenecarboxylic acid, 3-hydroxy-, 2-[ (2, 4, 5-trihydroxyphenyl) Methylene]hydrazide; 3-Hydroxy-N'-(2,4,5-trihydroxybenzylidene)-2-naphthohydrazide; Dyngo 49. Grades: ≥96%. CAS No. 1256493-34-1. Molecular formula: C18H14N2O5. Mole weight: 338.31. | |
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