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| Product | Description | |
|---|---|---|
| Dynole 34-2 | Dynole 34-2. Group: Biochemicals. Grades: Purified. CAS No. 1128165-88-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Dynole 34-2 | Dynole 34-2 is a dynamin I inhibitor with IC50 value of 1.3 μM. It also inhibits receptor-mediated endocytosis (RME) with IC50 value of 5.0 μM. Synonyms: 2-Cyano-3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-N-octyl-2-propenamide. Grade: ≥99% by HPLC. CAS No. 1128165-88-7. Molecular formula: C25H36N4O. Mole weight: 408.58. |  |
| Dynole 34-2 | Dynole 34-2 is a potent dynamin GTPase inhibitor (IC50s=6.9 and 14.2 μM for dynamin1 and dynamin2 GTPase activity, respectively) with antimitotic effect. Dynole 34-2 induces apoptosis, as revealed by cell blebbing, DNA fragmentation, and PARP cleavage. Dynole 34-2 also potently inhibits receptor mediated endocytosis (RME)[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1128165-88-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107545. |  |
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